Background
: There are very few cohort studies on the hypertension in family practice. In order to investigate epidemiological characteristics of hypertensive patients and assess the safety and tolerabiliy of newly prescribed antihypertensive monotherapies in Korean patients, a prospective study was carried out.

Methods : A total of 1,181 patients were observed from July 1997 to August 1999. At 2,4,8 and 12 weeks after initiation of antihypertensive monotherapy, the patients were evaluated for whether treatment is continued and development of any adverse reactions.

Results : Calcium channel blockers(CCBs) were the most commonly prescribed initial drug class(44.2%) in family practice, followed by angiotensin converting enzyme inhibitors(ACEI) (21.0%), angiotensin II receptor antagonists(ARA) (11.8%), B-blockers(9.6%), a-blockers(3.9%), and diuretics(3.6%), During the first 12 weeks, the percentage of subjects continuing their initial ACEIs(40.7%) was substantially lower than the percentages that of subjects continuing ARAs(66.2%), a- blockers*(63.0%), CCBs(61.3%), B-blockers(55.8%), and diuretics(53.5%), respectively(P<0.001), The following adverse reactions were detected: cough(7.5%), headache(6.1%), dizziness(3.9%), flushing(3.7%), and impotence(2.4%). The incidence of cough associated with ACEI(27.9%), was higher than those of other classes(P<0.01)

Conclusion : CCBs were the most commonly prescribed initial drug class in family practice, followed by ACEIs, ARAs, B-blockers, a-blockers, and diuretics. The tolerability of antihypertensive medication was the highest in Korean patients treated with ARAs, followed by CCBs, B-blockers, diuretic, a-blocker, and ACEIs.

Background
: With improvement of Medicine, prevalence of acute, infectious disease declined and Incidence of Coronary artery disease increased, in Korea. The causes of this finding are bad lifestyles, for example eating habit, insufficient physical activity and fitness, smoking and these are the major risk factors of chronic disease. Recent data suggest the important effect of physical activity and fitness on prevention of chronic disease. This study will show the frequency of leisure time physical activity and characteristics of people in Seoul according to physical activity.
Method: A modified version of Minnesota Leisure Time Physical Activity Assessment was adminis-tered to the people selected by Randm Digit Dialing, Mitofsky-Waksberg method from May to August, 1995. This report focused on time spent in specific activities during previous month and questions asked included frequency per month of engaging in activities.
Participiants were asked about cigarette smoking, alcohol, blood pressure, age, sex, periodic health examination, education. Responses were differentiated to create four categories of physical activity status ; inactive, regular active, irregular active.

Results : The final response rate was 136 persons(30.8%), for a total 441 persons. Among them, Man was 51 persons(37.5%) and aged 20 years and older. Proportion of people who reported being inactive, irregular active, regular active are 21, 83 and 32 persons. Women were more likely to report being inactive than men. The proportion of people in Seoul who reported an inactive status increased with increasing age, and shorter, less smoker, less drinker. The three most commonly repor-ted physical activities for both men and women are Calisthenics, Walking with pleasure, Climbing stairs.

Conclusion : We studied people in Seoul, selected by Random Digit sampling. The most commonly reported physical activities for both men and women was Calisthenics. The Proportion of people in Seoul reported an active status increased with decresing age and increasing height.