Background
: The new Bethesda System terminology has opened a series of problems about the atypical squamous cells of undetermined significance and low grade squamous intraepithelial lesion categories, particularly on their follow up.

Methods : We observe 12300 Pap smear examination, from Jan 1995 to Dec 1999, in the Health Promotion Center in a university hospital. Subjects were defined at the Health Promotion Center in a university hospital by electrical record and chart review.

Results : We find 48 cases of ASCUS and 33 cases of LSIL. When it is followed up by Pap smear, 34 cases of ASCUS are confirmed normal 19 cases (55.9%), benign cellular change 6 cases (17.6%), ASCUS 5 cases (14.7%), HSIL 4 cases (11.8%) and 27 cases of LSIL are confirmed normal 11 cases (40.7%), benign cellular change 3 cases (11.1%), ASCUS 3 cases (11.1%), LSIL 8 cases (29.6%), HSIL 2 cases (7.4%). 14 cases of ASCUS and 23 cases of LSIL are diagnosed by biopsy. Histologic results of 14 cases of ASCUS are confirmed cervicitis 10 cases (71.4%), moderate dysplasia 2 cases (14.3%), carcinoma in situ 2 cases (14.3%) and histologic results of 23 cases of LSIL are confirmed cervicitis 15 cases (65.2%), mild dysplasia 3 cases (13%), moderate dysplasia 3 cases (13%), severe dysplasia 1 case (4.3%), carcinoma in situ 1 case (4.3%), Pap smear only was used for follow-up at family medicine clinic and 14 cases (29.2%), 4 cases (12.1%) are follow-up loss.

Conclusion : After it is diagnosed ASCUS or LSIL lesion of Pap smear in healthy care visitors, Follow-up loss is high in only follow-up Pap smear examination and follow-up results are presented more severe lesions. To reduce follow-up loss, aggressive diagnosis and managements may be needed more than Pap smear follow-up examination.