Background : In recent years, the incidence of obesity increased in Koreans. The main cause suggested is the diet style of Korean changed to that of Western. It has been proved that obesity is a risk factor of an aggravating factor of hypertension and diabetes mellitus, cardiovascular disease, etc. Primary physician has been interested in the correlation of blood pressure with relative body weight and aging. The purpose of this study was to focus on the influence of age and relative body weight on blood pressure.
Methods : Subjects were collected from 2,068 adults who had received Adult Health Examination. That subjects were divided according to age, relative body weight and then the relation of blood pressure with age according to relative body weight and relation with relative body weight according to age were investigated.
Results : Systolic blood pressure increased significantly according to age in all male and female three weight groups and then increased significantly according to relative body weight in all male and female three age group except male seventh decade group. Diastolic blood pressure increased significantly according to age in all make and female three weight groups except male obesity group and then increased significantly according to the relative body weight in all make and female three age groups except male and female seventh decade groups. Systolic blood pressure has higher correlation with age than relative body weight and diastolic blood pressure has higher correlation with relative body weight in male. In female, systolic and diastolic blood pressure have higher correlations with age.
Conclusion : It can be suggested that blood pressure increase significantly according to aging process and relative body weight. These two factors have a little different effects to systolic and diastolic blood pressure according to sex. Relative body weight has more effect to diastolic blood pressure than systolic blood pressure in male.
Background : The mortality of coronary artery disease and cerebral vascular disease is increasing. The risk factors in the development of coronary artery disease is known as tobacco, hypertension, obesity, cholesterol, hyperlipidemia etc. The importance of lipoprotein(a) in the development of coro-nary artery disease is supported by the recent studies. The purpose of this study was to investigate the association of Lp(a) concentration and the other risk factor of coronary artery disease.
Methods : The concentration of Lp(a) was measured in 507 cases, free of disease and medications known to affect the lipid levels. Plasma Lp(a) concentration were measured by immunonephelometry.
Results : In men, Lp(a) were not associated with age. In women, Lp(a) concentration increased with age. If postmenopausal women were excluded, the relation between age and Lp(a) disappeared. Lp(a) levels had no relations with smoking, obesity, and hypertension.
Conclusion : These results suggested that Lp(a) level was a significant independent risk factor for coronary artery disease.