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Volume 40(6); November 2019

Editorial

The Current Status and Challenges of National Smoking Cessation Support Program in Korea
Seung-Won Oh
Korean J Fam Med 2019;40(6):351-352.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.40.6E

Citations

Citations to this article as recorded by  
  • Associations between Nicotine Dependence, Smartphone Usage Patterns, and Expected Compliance with a Smoking Cessation Application among Smokers
    Oh Beom Kwon, Chihoon Jung, Auk Kim, Sang Won Park, Gihwan Byeon, Seung-Joon Lee, Woo Jin Kim
    Healthcare Informatics Research.2024; 30(3): 224.     CrossRef
  • Factors Associated with Smokers Attending More Than One Smoking Cessation Clinic Visit
    Oh Beom Kwon, Chihoon Jung, Auk Kim, Gihwan Byeon, Seung-Joon Lee, Woo Jin Kim
    Journal of Clinical Medicine.2023; 12(23): 7222.     CrossRef
  • Effects of education methods on self-efficacy of smoking cessation counseling among medical students
    Ara Cho, Jeonggyu Lee, YunJin Kim, Byung Mann Cho, Sang Yeoup Lee, Eunhee Kong, Minjeong Kim, Jinseung Kim, Dong Sik Jung, Seongho Han
    PeerJ.2021; 9: e11408.     CrossRef
  • Sex- and Age-Specific Trends in Cardiovascular Health in Korea, 2007–2018
    So Mi Jemma Cho, Hokyou Lee, Hyeon Chang Kim
    Korean Circulation Journal.2021; 51(11): 922.     CrossRef
  • 5,853 View
  • 74 Download
  • 6 Web of Science
  • 4 Crossref

Review Article

Cancer Survivorship in Primary Care
Jihun Kang, Eun Ju Park, Jungkwon Lee
Korean J Fam Med 2019;40(6):353-361.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.19.0108
With the early detection of cancer and improvement in cancer therapy, the number of cancer survivors is rapidly increasing. This number is expected to reach 2 million by the end of 2019. Cancer survivors struggle with not only cancer-related health problems but also diverse acute and chronic diseases. These health issues make cancer survivorship more complex, and proper care coordination is necessary. This study aimed to summarize the definition of cancer experience and management of cancer survivors, specifically focused on gastric, colorectal, lung, breast, thyroid, prostate, and cervical cancers. Furthermore, it aimed to discuss the role of primary care in cancer survivorship and survivorship care models and the National Policy for Cancer Survivors and Future Challenges.

Citations

Citations to this article as recorded by  
  • Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial
    Wonyoung Jung, Alice Ahn, Genehee Lee, Sunga Kong, Danbee Kang, Dongok Lee, Tae Eun Kim, Young Mog Shim, Hong Kwan Kim, Jongho Cho, Juhee Cho, Dong Wook Shin
    JMIR Research Protocols.2024; 13: e54707.     CrossRef
  • It’s Not Always Easy: Cancer Survivorship Care in Primary Care Settings
    Mirna Becevic, Allison B. Anbari, Jane A. McElroy
    Journal of Cancer Education.2023; 38(5): 1592.     CrossRef
  • Factors Associated with Sleep Disorder among Korean Cancer Survivors: A Cross-Sectional Study
    Hyeonjin Cho, Wonyoung Jung, Dong Wook Shin, Jinyoung Shin, Yun-Mi Song
    Korean Journal of Family Medicine.2023; 44(4): 224.     CrossRef
  • Exploring socio-demographic, physical, psychological, and quality of life-related factors related with fear of cancer recurrence in stomach cancer survivors: a cross-sectional study
    Jinyoung Shin, Dong Wook Shin, Jungkwon Lee, JiHye Hwang, Ji Eun Lee, BeLong Cho, Yun–Mi Song
    BMC Cancer.2022;[Epub]     CrossRef
  • Interdisciplinary Approaches to Survivorship with a Focus on the Low-grade and Benign Brain Tumor Populations
    Stacey L. Worrell, Michelle L. Kirschner, Rhonna S. Shatz, Soma Sengupta, Melissa G. Erickson
    Current Oncology Reports.2021;[Epub]     CrossRef
  • 7,643 View
  • 149 Download
  • 6 Web of Science
  • 5 Crossref

Original Articles

Comparison of Vitex agnus-castus Extracts with Placebo in Reducing Menopausal Symptoms: A Randomized Double-Blind Study
Rozita Naseri, Vahid Farnia, Katayoun Yazdchi, Mostafa Alikhani, Behrad Basanj, Safora Salemi
Korean J Fam Med 2019;40(6):362-367.   Published online May 9, 2019
DOI: https://doi.org/10.4082/kjfm.18.0067
Background
Menopausal symptoms have remarkable negative effects on women’s quality of life, justifying the need to assess various therapeutic options. This research aimed to determine the effectiveness of Vitex agnus-castus extracts in alleviating menopausal symptoms in comparison with that of placebo.
Methods
This study was a randomized controlled double-blind clinical trial with a study group of 52 women referred to a clinic in Kermanshah in 2017. The participants were randomly divided into two groups: Vitex group (26 subjects) and placebo group (26 subjects). Menopausal symptoms were assessed using the Greene Scale before and 8 weeks after the intervention.
Results
After the intervention, the mean scores for total menopausal disorder, anxiety, and vasomotor dysfunction were significantly lower in the Vitex group than in the placebo group (P<0.05). The mean scores of the variables of somatic complications, depression, and sexual dysfunction did not show significant differences between the Vitex and placebo groups (P>0.05).
Conclusion
Administration of Vitex agnus-castus extracts as a phytoestrogenic medicine can alleviate menopausal symptoms in women.

Citations

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  • Treatment of Menopausal Symptoms with Herbal Medicines: A Review
    Pranay Wal, Indu Singh, Deependra Singh, Manju Rawat Singh, Ankita Wal
    Current Women s Health Reviews.2025;[Epub]     CrossRef
  • Scabiosa artropurperea var.maritima aqueous extracts improve in vivo fertility parameters and in vitro granulosa cell steroidogenesis in Ewe
    Wijden Niama, Samia Ben Said, Christelle Rame, Kahena Bouzid, Ahlem Bartakiz, Pascal Froment, Mokhtar Mahouachi, Joëlle Dupont
    Theriogenology.2025; 235: 9.     CrossRef
  • Exploring the Efficacy and Safety of Black Cohosh (Cimicifuga racemosa) in Menopausal Symptom Management
    Kritiksha Hedaoo, Ankit K. Badge, Yugeshwari R. Tiwade, Nandkishor J. Bankar, Vaishnavi H. Mishra
    Journal of Mid-life Health.2024; 15(1): 5.     CrossRef
  • Vitex agnus-castus (VAC) plant commonly used in Aydın province, Turkey: women's menstrual and menopausal symptoms
    Serpil Abalı Çetin, Fatma Mutlu
    Journal of Herbal Medicine.2024; 46: 100900.     CrossRef
  • Unlocking nature’s secrets: Medicinal plants for enhanced female fertility
    Karishma Singh, Roger Coopoosamy, Alabi David, Kuben Naidoo
    Journal of Medicinal Plants for Economic Development.2024;[Epub]     CrossRef
  • Effects of nutritional interventions on the severity of depressive and anxiety symptoms of women in the menopausal transition and menopause: a systematic review, meta-analysis, and meta-regression
    Ruth B. Grigolon, Gilciane Ceolin, Yan Deng, Alexander Bambokian, Elena Koning, Jennifer Fabe, Maiara Lima, Fernando Gerchman, Claudio N. Soares, Elisa Brietzke, Fabiano A. Gomes
    Menopause.2023; 30(1): 95.     CrossRef
  • Sexual dysfunction: an interdisciplinary problem of classical gynecology
    Natalia M. Podzolkova, Liliana V. Sumyatina
    Gynecology.2023; 25(1): 95.     CrossRef
  • A hypothesis to explain the potential influence of hormones on the severity of autism spectrum conditions in women
    Rosita Dangmann
    Medical Hypotheses.2023; 178: 111136.     CrossRef
  • Does Vitex Agnus-Castus L. Have Deleterious Effect on Fertility and Pregnancy Outcome? An Experimental Study on Rats for Prediction of Its Safety
    Fateme Sadat Najib, Tahereh Poordast, Monireh Sufi Mahmudi, Zahra Shiravani, Niloofar Namazi, Gholamhossein Ranjbar Omrani
    Journal of Pharmacopuncture.2022; 25(2): 106.     CrossRef
  • Traditional Medicinal Uses, Phytochemistry, Biological Properties, and Health Applications of Vitex sp.
    Nurkhalida Kamal, Nurul Syahidah Mio Asni, Ivana Nur Allisya Rozlan, Muhammad Aniq Hamzah Mohd Azmi, Noor Wini Mazlan, Ahmed Mediani, Syarul Nataqain Baharum, Jalifah Latip, Suvik Assaw, Ru Angelie Edrada-Ebel
    Plants.2022; 11(15): 1944.     CrossRef
  • Menopause symptoms in women and its relation with using complementary and alternative medicines: A survey in southeast Iran
    Mahlagha Dehghan, Zahra Isari, Mohammad Hossein Abbaszadeh, Asma Ghonchehpour
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Perimenopause and Mental Health
    Nicole Leistikow, Milena H. Smith
    Advances in Psychiatry and Behavioral Health.2022; 2(1): 107.     CrossRef
  • Comparison of Cinnamon and Vitex on Improving Sexual Function in Postmenopausal Women: A Triple-blind Randomized Clinical Trial
    Tanya Koliji, Zohrah Keshavarz, Faraz Mojab, Malihe Nasiri, Elham Zare
    Jundishapur Journal of Natural Pharmaceutical Products.2022;[Epub]     CrossRef
  • Global survey of medicinal plants during lactation and postpartum recovery: Evolutionary perspectives and contemporary health implications
    Lindiwe Sibeko, Timothy Johns
    Journal of Ethnopharmacology.2021; 270: 113812.     CrossRef
  • The Effect of Jazar Supplement on Quality of Life and Sexual Function in Postmenopausal Women: A Double-Blind, Randomized, Placebo-Controlled Trial
    Sousan Hafizi, Alireza Abbassian, Malihe Tabarrai, Deborah A. Kennedy
    Evidence-Based Complementary and Alternative Medicine.2021; 2021: 1.     CrossRef
  • Investigation of the role of herbal medicine, acupressure, and acupuncture in the menopausal symptoms: An evidence-based systematic review study
    Abed Ebrahimi, Naeimeh Tayebi, Ahmadinezhad Fatemeh, Marzieh Akbarzadeh
    Journal of Family Medicine and Primary Care.2020; 9(6): 2638.     CrossRef
  • Vitex agnus-castus L.: Main Features and Nutraceutical Perspectives
    Eliana B. Souto, Alessandra Durazzo, Amirhossein Nazhand, Massimo Lucarini, Massimo Zaccardelli, Selma B. Souto, Amelia M. Silva, Patricia Severino, Ettore Novellino, Antonello Santini
    Forests.2020; 11(7): 761.     CrossRef
  • 15,273 View
  • 348 Download
  • 14 Web of Science
  • 17 Crossref
A Comparative Study on the Effectiveness of Individual and Group Play Therapy on Symptoms of Oppositional Defiant Disorder among Children
Narges Morshed, Mohammad Babamiri, Mehdi Zemestani, Nasim Alipour
Korean J Fam Med 2019;40(6):368-372.   Published online January 9, 2019
DOI: https://doi.org/10.4082/kjfm.18.0045
Background
This research compared the effectiveness of play therapy provided individually or in groups for oppositional defiant disorder (ODD) symptoms among children.
Methods
This was a randomized controlled trial that used a multi-stage random sampling method. Participants included 45 children aged 6 to 10 years old with ODD, all of whom had been referred to medical consultation centers in Ahvaz, Iran in 2012. Experimental groups consisted of 15 children receiving individual play therapy and 15 receiving group play therapy, while the control group consisted of 15 randomly selected children. Data were collected using the child behavior checklist parent report form and teacher report form, along with clinical interviews with the parents. Play therapy took place weekly for eight total sessions; individual sessions lasted 45 minutes each, while group sessions were each 60 minutes in duration. Participants were assessed in three stages, including preintervention, post-intervention, and at 2-month follow-up. PASW SPSS ver. 18.0 software (SPSS Inc., Chicago, IL, USA) and analysis of covariance analysis methods were used to analyze data.
Results
Results showed meaningful decreases in ODD symptoms in the experimental groups in comparison with the control group, based on parent reporting (P≤0.001 and F=129.40) and the teacher reports additionally showed meaningful decreases in ODD symptoms in the experimental groups compared to the control group, (P≤0.001 and F=93.14). Furthermore, the effects were maintained after 2 months.
Conclusion
This research supports the efficacy of individual and group play therapy for the treatment of ODD in children, as well as the consistency of the effects at 2-month follow-up.

Citations

Citations to this article as recorded by  
  • Behavioural interventions targeting the prevention and treatment of young children’s mental health problems in low- and middle-income countries: a scoping review
    Getachew Mullu Kassa, Zhiyuan Yu, Fentahun Minwuyelet, Deborah Gross
    Journal of Global Health.2025;[Epub]     CrossRef
  • The effect of child-centered play therapy (CCPT) on the symptoms of oppositional defiant disorder in preschool children
    Rasoul Heshmati, Khalil Esmailpour, Rasoul Hajsaghati, Fereshteh Azizi Barenji
    International Journal of Play.2023; 12(2): 193.     CrossRef
  • A systematic review of evidence-based interventions for child and adolescent mental health problems in low- and middle-income countries
    Wagner Silva Ribeiro, Antônio José Grande, Mauricio Scopel Hoffmann, Carolina Ziebold, David McDaid, Andra Fry, Clayton Peixoto, Cláudio Miranda, Derek King, Cristiane Damiani Tomasi, Christine Faustino, Sandra Leone, Silvia Moraes, Antonio Augusto Schäfe
    Comprehensive Psychiatry.2022; : 152358.     CrossRef
  • Comparison of the Effectiveness of Individual and Group Play Therapy on Coping Behaviors in Primary School Students with Attention Deficit Hyperactivity Disorder
    Elahe Nayebi, Reza Pasha, Saeed Bakhtiyarpour, Zahra Eftekhar Saadi
    Quarterly Journal of Child Mental Health.2020; 7(2): 120.     CrossRef
  • 6,814 View
  • 259 Download
  • 4 Web of Science
  • 4 Crossref
Short-Term Success Rates of Smoking Cessation Support Programs and Factors Predicting Smoking Relapse: Using Data from a Smoking Cessation Clinic in a Hospital
Seung-Hyun Yu, Myeong-Jun Kim, Jin Jeon, Hoon-Ki Park, Hwan-Sik Hwang, Kye-Yeung Park
Korean J Fam Med 2019;40(6):373-379.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.18.0094
Background
Although the number of medical institutions running a smoking cessation clinic is on the rise, there remains a paucity of research on the long- and short-term success rates of smoking cessation programs, as well as on smoking relapse rates, before and after project implementation. This study assessed the general characteristics of patients visiting the smoking cessation clinic, success rate of smoking cessation in the short term, and risks of relapse.
Methods
Medical records from March 2015 to April 2017 were analyzed and telephone surveys were conducted with 151 smokers who visited a hospital smoking cessation clinic from March 2015 to April 2017.
Results
Of the 139 smokers who were eligible for follow-up, 22 (15.8%) failed to quit smoking initially. The clinic’s 6-month success rate of smoking cessation was 64.83%. Those with higher medication compliance had a lower risk of primary failure (odds ratio, 0.056; 95% confidence interval, 0.005–0.609), whereas those with higher age (hazard ratio [HR], 0.128; P=0.0252) and a greater number of visits to the clinic (HR, 0.274; P=0.0124) had a lower risk of relapsing.
Conclusion
The risk of primary failure to quit was higher with low medication compliance, and that of relapsing was higher with lower age and fewer number of clinic visits. Various evaluation and analysis methods can be carried out in the future based on the accumulated data for maintenance of smoking cessation and relapse prevention.

Citations

Citations to this article as recorded by  
  • Development of a Risk Score to Predict Short-term Smoking Relapse Following an Inpatient Smoking Cessation Intervention
    Hwang Sik Shin, Yoon Hyung Park, Sung Soo Lee, Yong Jin Cho, Jun Tack Kwon, Youngs Chang, Mee-Ri Lee, Young Hwangbo
    Asia Pacific Journal of Public Health.2024; 36(4): 329.     CrossRef
  • Associations between Nicotine Dependence, Smartphone Usage Patterns, and Expected Compliance with a Smoking Cessation Application among Smokers
    Oh Beom Kwon, Chihoon Jung, Auk Kim, Sang Won Park, Gihwan Byeon, Seung-Joon Lee, Woo Jin Kim
    Healthcare Informatics Research.2024; 30(3): 224.     CrossRef
  • The Current Status and Challenges of National Smoking Cessation Support Program in Korea
    Seung-Won Oh
    Korean Journal of Family Medicine.2019; 40(6): 351.     CrossRef
  • 5,727 View
  • 106 Download
  • 3 Web of Science
  • 3 Crossref
Association between Serum-Ferritin Levels and Sleep Duration, Stress, Depression, and Suicidal Ideation in Older Koreans: Fifth Korea National Health and Nutrition Examination Survey 2010–2012
Kyung Mi Kim, Hye Rim Hwang, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Sung In Chung
Korean J Fam Med 2019;40(6):380-387.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.18.0097
Background
Serum-ferritin levels may be associated with psychiatric symptoms among the elderly; however, this association has not been extensively studied. The aim of this study was to evaluate the association between serumferritin levels and mental health issues in older Koreans.
Methods
This cross-sectional study included large-scale national data from the Korea National Health and Nutrition Examination Survey 2010–2012. In total, 1,802 older Koreans (≥65 years old) were included. The assessed psychiatric symptoms included short sleep duration, stress, depressed mood, and suicidal ideation. Any association between serum-ferritin levels and mental health issues according to sex was examined using logistic regression analysis.
Results
The prevalence of short sleep duration, stress, depressed mood, and suicidal ideation was 50.9%, 21.7%, 18.2%, and 22.5%, respectively. In men, suicidal ideation decreased with increased serum-ferritin levels after multivariate adjustment for sociodemographic and lifestyle factors and comorbidities. The odds ratios (OR) and 95% confidence interval (CI) of suicidal ideation by quartiles of serum-ferritin level were 1 (reference), 1.132 (95% CI, 0.569–2.252), 0.453 (95% CI, 0.217–0.945), and 0.608 (95% CI, 0.295–1.253), respectively, (P for trend=0.039). In women, no trend was observed. However, compared to the lowest quartile, short sleep duration (<7 h) and stress perception were significantly decreased in the third quartile, with odds ratios of 0.601 (95% CI, 0.461–0.888), and 0.606 (95% CI, 0.386–0.952), respectively.
Conclusion
Moderate serum-ferritin levels were associated with decreased risk for suicide ideation in men, and were associated with decreased short sleep duration and stress perception in women.

Citations

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  • Association between suicide attempts and anemia in late-life depression inpatients
    Jie Li, Lan Wang, Ziyi Wang, Fengxue Zhao, Yadi Sun, Ying Lu, Lei Yang
    BMC Geriatrics.2024;[Epub]     CrossRef
  • Sleep quality and Laboratory Findings in Patients with Varicose Vein Leg Pain
    Acır Ibrahim, Atay Zeynep Vildan Okudan , Atay Mehmet , Yayla Vildan
    Journal of Neuroscience and Neurological Disorders.2023; 7(1): 022.     CrossRef
  • Alteration of Inflammatory Parameters and Psychological Post-Traumatic Syndrome in Long-COVID Patients
    Irma Clemente, Gaia Sinatti, Antonio Cirella, Silvano Junior Santini, Clara Balsano
    International Journal of Environmental Research and Public Health.2022; 19(12): 7103.     CrossRef
  • Psychological and Cognitive Effects of Long COVID: A Narrative Review Focusing on the Assessment and Rehabilitative Approach
    Rosaria De Luca, Mirjam Bonanno, Rocco Salvatore Calabrò
    Journal of Clinical Medicine.2022; 11(21): 6554.     CrossRef
  • Suicidal Ideation in Major Depressed Individuals: Role of Type D Personality
    Mokhtar Abdelhakim Laoufi, Benjamin Wacquier, Tristan Lartigolle, Gwenolé Loas, Matthieu Hein
    Journal of Clinical Medicine.2022; 11(22): 6611.     CrossRef
  • 10,464 View
  • 129 Download
  • 4 Web of Science
  • 5 Crossref
Prevalence of and Risk Factors for Diseases in Korean Americans and Native Koreans Undergoing Health Checkup
So Young Jo, Hyojin Park, Byoung Kwon Lee, Su Jung Baik, Hyun Ju Lee, Yoo Mi Park
Korean J Fam Med 2019;40(6):388-394.   Published online October 23, 2019
DOI: https://doi.org/10.4082/kjfm.18.0093
Background
Korean Americans constitute the fifth largest subgroup in the Asian American population. Despite their increasing population, research and guidelines regarding their health status assessment and disease screening are lacking. This study aimed to compare the prevalence of diseases in Korean Americans and native Koreans to determine the risk factors and guidelines for disease screening.
Methods
Patients who visited the Gangnam Severance Hospital from February 2010 to May 2015 for a health checkup were enrolled in this study. Baseline characteristics, laboratory data, and the organs (stomach, colon, thyroid, brain, prostate, lung, liver, kidney, pancreas, adrenal gland, and heart) of patients were examined. Data regarding patients’ dietary patterns were also obtained. Overall, 1,514 Korean Americans (group 1) and 1,514 native Koreans (group 2) were enrolled.
Results
The following diseases were more prevalent in group 1 than in group 2: reflux esophagitis (12.9% vs. 10%), gastric ulcer (3.0% vs. 5.5%), colorectal polyp (37.7% vs. 28.7%), hemorrhoids (32.2% vs. 29.9%), and benign prostatic hyperplasia (30.2% vs. 14.3%). Although not statistically significant, coronary artery disease has a high prevalence rate of >20% in both groups. Dietary patterns were not significant between the two groups.
Conclusion
This study showed that the prevalence of several diseases in Korean Americans differed from that observed in native Koreans. Therefore, a foundation for setting up new guidelines for disease screening among Korean Americans is established.

Citations

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  • The Relationship Between the Incidence of Coronary Heart Disease and Ethnic Minorities
    Yerdan Maidyrov, Salim Berkinbayev, Kairat Karibayev, Shynar Tanabayeva, Ildar Fakhradiyev, Gani Tulepbergenov, Aizat Aimakhanova, Aliya Alimbayeva
    Experimental and Applied Biomedical Research (EABR).2023; 24(2): 125.     CrossRef
  • Association between haemorrhoids and Graves’ disease: a retrospective cohort study using data from Taiwan’s Longitudinal Health Insurance Database
    Shang-Rong Zhong, Hsin-Hung Chen, Chun-Cheng Liao, Chun-Hung Su, Hei-Tung Yip, Chia-Hung Kao
    BMJ Open.2021; 11(12): e053442.     CrossRef
  • Association of Hemorrhoids With Hashimoto's Thyroiditis and Associated Comorbidities: A Nationwide Population-Based Cohort Study
    Sheng-Pang Hsu, Hsin-Hung Chen, Tzu-Yuan Wang, Chun-Wei Ho, Ming-Chia Hsieh, Hei-Tung Yip, Chia-Hung Kao
    Frontiers in Endocrinology.2020;[Epub]     CrossRef
  • 6,744 View
  • 88 Download
  • 2 Web of Science
  • 3 Crossref
Association between Abdominal Obesity and Oxidative Stress in Korean Adults
Im Jeong Na, Jae Sun Park, Sat Byul Park
Korean J Fam Med 2019;40(6):395-398.   Published online October 31, 2019
DOI: https://doi.org/10.4082/kjfm.18.0086
Background
Obesity causes several changes in the body and is associated with both inflammation and oxidative stress. However, the relationship between abdominal obesity, diacron-reactive oxygen metabolites (d-ROMs), and biological antioxidant potential (BAP) levels in Korean adults has not yet been proved. The aim of this study was to evaluate the association between d-ROMs, BAP levels, and abdominal obesity in the Korean adult population using clinical data.
Methods
A total of 2,367 individuals, aged 18–86 years, were identified from health check-up examination records at a university hospital, between January 2015 and August 2016. Clinical and biochemical parameters, including waist circumference, lipid profile, alcohol drinking status, and smoking status, were investigated. Oxidative stress levels, viz., d-ROM concentration and antioxidant capacity, viz., BAP, were measured.
Results
Subjects with abdominal obesity presented significantly higher levels of d-ROMs compared to those with a normal waist circumference (P<0.001). After adjusting for age, sex, alcohol drinking status; smoking status; and triglyceride, low-density lipoprotein levels were found to have a significant positive correlation with abdominal obesity (P<0.001). BAP did not significantly correlate with abdominal obesity.
Conclusion
We observed a positive association between abdominal obesity and d-ROM concentration. This result indicates that abdominal obesity can increase oxidative stress and may affect the pathways involved in obesity, such as the inflammatory pathway. Such correlation analyses were helpful in revealing the causes, as well as methods to reduce, oxidative stress.

Citations

Citations to this article as recorded by  
  • Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study
    Xiaoqiang Li, Xiangmao Zhou, Hui Du, Hui Wang, Zhijian Tan, Yaqing Zeng, Zhibin Song, Guifeng Zhang
    Frontiers in Public Health.2025;[Epub]     CrossRef
  • J-Shaped Relationship Between Weight-Adjusted-Waist Index and Cardiovascular Disease Risk in Hypertensive Patients with Obstructive Sleep Apnea: A Cohort Study
    Jianwen Zhao, Xintian Cai, Junli Hu, Shuaiwei Song, Qing Zhu, Di Shen, Wenbo Yang, Qin Luo, Xiaoguang Yao, Delian Zhang, Jing Hong, Nanfang Li
    Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 2671.     CrossRef
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    Basmah N. Aldosari, Hesham M. Tawfeek, Ahmed A. H. Abdellatif, Alanood Sunhat Almurshedi, Iman Mohammed Alfagih, Bushra Tawfeeq AlQuadeib, Asmaa Youssef A. Abbas, Heba M. Mohammed, Yasser A. Hassan, Mohamed H. Fayed, Nahla Sameh Tolba
    Drug Development and Industrial Pharmacy.2024; 50(7): 605.     CrossRef
  • Weight-adjusted waist index and cardiovascular disease: a population-based study in Ravansar, Iran
    Sepehr Sadafi, Ali Azizi, Ebrahim Shakiba, Yahya Pasdar
    Archives of Public Health.2024;[Epub]     CrossRef
  • Association between the weight-adjusted waist index and stroke: a cross-sectional study
    Jiayi Ye, Yanjie Hu, Xinrong Chen, Zhe Yin, Xingzhu Yuan, Liping Huang, Ka Li
    BMC Public Health.2023;[Epub]     CrossRef
  • Associations of oxidative balance score with total abdominal fat mass and visceral adipose tissue mass percentages among young and middle-aged adults: findings from NHANES 2011–2018
    Kai Wang, Minggang Deng, Jinyi Wu, Lingli Luo, Rui Chen, Fang Liu, Jiaqi Nie, Fengxi Tao, Qingwen Li, Xin Luo, Fang Xia
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • The Effects of Antioxidants from Natural Products on Obesity, Dyslipidemia, Diabetes and Their Molecular Signaling Mechanism
    Chindiana Khutami, Sri Adi Sumiwi, Nur Kusaira Khairul Ikram, Muchtaridi Muchtaridi
    International Journal of Molecular Sciences.2022; 23(4): 2056.     CrossRef
  • A Comparison Study on the Therapeutic Effect of High Protein Diets Based on Pork Protein versus Soybean Protein on Obese Mice
    Songsong Jiang, Shanshan Ji, Xinlei Tang, Tao Wang, Hengpeng Wang, Xiangren Meng
    Foods.2022; 11(9): 1227.     CrossRef
  • Association between oxidative balance score and neck circumference in Korean adults
    Jina Yeo, In Cheol Hwang, Hong Yup Ahn
    Obesity Research & Clinical Practice.2022; 16(4): 343.     CrossRef
  • Factors of Obesity and Metabolically Healthy Obesity in Asia
    Bryan J. Mathis, Kiyoji Tanaka, Yuji Hiramatsu
    Medicina.2022; 58(9): 1271.     CrossRef
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  • 99 Download
  • 10 Web of Science
  • 10 Crossref
Relationship between Alcohol Consumption and Ocular Pressure according to Facial Flushing in Korean Men with Obesity
Sami Lee, Jong-Sung Kim, Sung Soo Kim, Jin-Gyu Jung, Seok-Joon Yoon, Yuri Seo, Jihan Kim, Yoon Kyung Bae, Ja Young Lee
Korean J Fam Med 2019;40(6):399-405.   Published online October 31, 2019
DOI: https://doi.org/10.4082/kjfm.18.0131
Background
This study aimed to examine the relationship between alcohol consumption and intraocular pressure (IOP) according to facial flushing in Korean men with obesity.
Methods
The study included 479 Korean men with a body mass index of ≥25 kg/m2 (75 non-drinkers, 174 with drinking-related facial flushing, and 230 without facial flushing) who underwent health check-ups between October 1, 2016 and March 31, 2017. Multivariate logistic regression was used to assess the relationship between alcohol consumption and high IOP (≥21 mm Hg).
Results
Flushers consuming ≤16 drinks per week had a significantly higher risk of high IOP than non-drinkers, depending on alcohol consumption (≤8 standard drinks: odds ratio [OR], 4.49; 95% confidence interval [CI], 1.05– 19.25; >8 but ≤16 standard drinks: OR, 8.14; 95% CI, 1.37–48.45). However, when the consumption was >16 drinks per week, the high IOP risk did not significantly increase (OR, 0.71; 95% CI, 0.05–10.69). In addition, there was no significant relationship between alcohol consumption and high IOP among non-flushers consuming ≤8 drinks per week (OR, 2.07; 95% CI, 0.52–8.19). However, a significantly increased risk of high IOP was observed among nonflushers consuming >8 drinks per week, depending on alcohol consumption (>8 but ≤16 standard drinks: OR, 4.84; 95% CI, 1.14–20.61; >16 standard drinks: OR, 4.08; 95% CI, 1.02–16.26).
Conclusion
This study suggests that obese men with alcohol flush reactions may have an increased risk of high IOP with the consumption of smaller amounts of alcohol than non-flushers.

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Case Report
Epileptic Seizure Due to Disulfiram Treatment
Habib Erensoy, Ahmet Emre Sargin
Korean J Fam Med 2019;40(6):406-408.   Published online January 7, 2019
DOI: https://doi.org/10.4082/kjfm.18.0014
Disulfiram has been used for the treatment of alcohol dependence for nearly 65 years and is approved by the Food and Drug Administration. It causes negative reinforcement by accumulating toxic acetaldehyde due to irreversible inhibition of aldehyde dehydrogenase. Disulfiram has very few side effects when taken without alcohol. Epileptic seizure induction is a rare side effect in therapeutic doses, and its mechanism is unknown. We present a patient with a single epileptic seizure which was thought to be due to disulfiram used in the treatment of alcohol dependence. We did not find it ethical to administer disulfiram again because the patient discontinued alcohol use and was afraid of epileptic seizures.

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    American Journal of Therapeutics.2024; 31(4): e422.     CrossRef
  • Anticancer Effects of New Disulfiram Analogs
    Omeima Abdullah, Christopher A. Beaudoin, Ziad Omran
    Biological and Pharmaceutical Bulletin.2024; 47(11): 1804.     CrossRef
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    Violeta Nogueira, Mafalda Azevedo Mendes, Inês Pereira, Joana Teixeira
    BMJ Case Reports.2021; 14(3): e236296.     CrossRef
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