Background Several studies have suggested that breastfeeding has a positive effect on long-term obesity, diabetes, hypertension, and hyperlipidemia. This study aimed to examine maternal bone health, muscle mass, and obesity based on breastfeeding duration.
Methods This study was based on the Korea National Health and Nutrition Examination Survey 2010–2011. We selected 2,027 elderly women by screening survey participants with a history of delivery. Multivariate logistic regression analyses were performed to estimate the odds ratios (ORs) of sarcopenia, osteoporosis, and obesity among four breastfeeding groups.
Results The OR of sarcopenia significantly decreased with increasing breastfeeding duration (OR, 0.27; 95% confidence interval [CI], 0.11–0.65; P for trend <0.001), whereas the OR of obesity significantly increased with increasing breastfeeding duration (OR, 2.56; 95% CI, 1.43–4.60; P for trend=0.009) after adjusting for potential confounding variables. We also found a positive correlation between the duration since last delivery and sarcopenia.
Conclusion Our results suggest a negative correlation between prolonged breastfeeding and the prevalence of sarcopenia, and a positive correlation between prolonged breastfeeding and the prevalence of obesity. Further studies are needed to clarify the relationship between breastfeeding and sarcopenia in the future.
Citations
Citations to this article as recorded by
Association of breastfeeding duration with longitudinal changes in vertebral bone marrow, paraspinal muscle composition, and metabolic parameters in premenopausal women over five years N. Hesse, Y. Stohldreier, S. Schlaeger, S. Theuerl, O. Dietrich, H. Hermann, I. Kaiser, J. Seissler, E. Pappa, U. Ferrari, A.S. Gersing European Journal of Radiology.2026; 195: 112514. CrossRef
Interventions and Programs to Promote Breastfeeding in Arabic-Speaking Countries: A Scoping Review Basil H. Aboul-Enein, Elizabeth Dodge, Nada Benajiba, Ruth M. Mabry Maternal and Child Health Journal.2023; 27(5): 774. CrossRef
Breastfeeding Duration Is Associated with the Risk of Tooth Loss, Chewing Difficulty, and Undernutrition among Older Korean Women: Results of the Korea National Health and Nutrition Examination Survey (KNHANES) 2013–2015 Ye Rang Jo, Yoo Kyoung Park, Hee-Sook Lim Nutrients.2023; 15(24): 5024. CrossRef
Association of total lifetime breastfeeding duration with midlife handgrip strength: findings from Project Viva Irasema C. Paster, Pi-i D. Lin, Sheryl L. Rifas-Shiman, Wei Perng, Jorge E. Chavarro, Emily Oken BMC Women's Health.2022;[Epub] CrossRef
Breastfeeding and Sarcopenia in Later Life Jungun Lee Korean Journal of Family Medicine.2019; 40(3): 133. CrossRef
Background Previous observational epidemiological studies have shown inconsistent results on the relationship between hypnotics use and risk of cancer. To determine the association between hypnotics use and risk of cancer, we conducted a meta-analysis of available literature.
Methods We searched databases PubMed, EMBASE, and the bibliographies of relevant articles to locate additional publications in February 2016. Three evaluators independently reviewed and selected eligible studies based on pre-determined selection criteria.
Results A total of six observational epidemiological studies including three case-control studies and three cohort studies, which involved 1,830,434 participants (202,629 hypnotics users and 1,627,805 non-users), were included in the final analyses. In a random-effects meta-analysis, compared with non-use of hypnotics, the odds ratio for overall hypnotics use was 1.29 for various cancers (95% confidence interval, 1.08–1.53). Subgroup meta-analyses by various factors such as study design, type of case-control study, study region, and methodological quality of study revealed consistent findings.
Conclusion Our findings from a meta-analysis of low-biased epidemiological studies suggested evidence linking the use of hypnotics to an increased risk of cancers. The results should be cautiously interpreted because of considerable heterogeneity with a high I square value.
Citations
Citations to this article as recorded by
Benzodiazepine Use and Long-Term Mortality in South Korean Adult Population: A Cohort Study Tak Kyu Oh, Hye Youn Park, In-Ae Song Yonsei Medical Journal.2021; 62(6): 528. CrossRef
Hypnotics and Risk of Cancer: A Meta-Analysis of Observational Studies Tzu-Rong Peng, Li-Jou Yang, Ta-Wei Wu, You-Chen Chao Medicina.2020; 56(10): 513. CrossRef
Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit Daniel F. Kripke F1000Research.2018; 5: 918. CrossRef
First
Prev
