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"Eung-Du Kim"

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"Eung-Du Kim"

Original Articles
Relationship between Smoking and Abdominal Aorta Calcification on Computed Tomography
Jin-Gyu Jung, Li-Tzy Wu, Jong-Sung Kim, Eung-Du Kim, Seok-Joon Yoon
Korean J Fam Med 2019;40(4):248-253.   Published online January 4, 2019
DOI: https://doi.org/10.4082/kjfm.17.0098
Background
Cigarette smoking increases the risk of atherosclerosis, which often develops as vascular calcification on radiologic examinations. This study evaluated the relationship between smoking-related factors and incidental abdominal aorta calcification (AAC) detected by computed tomography (CT) among middle-aged and elderly men.
Methods
We assessed the abdominal CT findings of 218 men aged 40 to 81 years who underwent health checkups. The associations between smoking factors and AAC were analyzed using logistic regression analysis to adjust for confounding variables such as age, lifestyle factors, and chronic diseases.
Results
Adjusting for confounding variables, the risk of AAC was significantly increased in association with smoking for at least 20 years (adjusted odds ratio [AOR], 5.22; 95% confidence interval [CI], 1.82–14.93), smoking 10+ pack-years (10–20 pack-years: AOR, 4.54; 95% CI, 1.07–5.68; >20 pack-years: AOR, 5.28; 95% CI, 2.10–13.31), and a history of smoking (former smoker: AOR, 2.10; 95% CI, 1.07–5.68; current smoker: AOR, 5.05; 95% CI, 2.08–12.26). In terms of the daily smoking amount, even a low smoking level increased the risk of AAC.
Conclusion
These findings suggest that smoking for 20+ years, smoking 10+ pack-years, and even a low level of smoking daily increases the likelihood of developing AAC. Clinicians should recommend that patients quit smoking and stress the importance of smoking duration when promoting health in middle-aged and elderly patients.

Citations

Citations to this article as recorded by  
  • Association of Smoking and Alcohol with Abdominal Aortic Calcification in the General Middle-Aged and Elderly Populations
    Yinze Ji, Naqiang Lv, Aimin Dang
    Reviews in Cardiovascular Medicine.2025;[Epub]     CrossRef
  • Vascular calcification in kidney stone formers: the impact of age and stone composition
    Alon Bnaya, Ilan Z Kafka, Hezi Barhoum, Linda Shavit
    Urolithiasis.2024;[Epub]     CrossRef
  • Association of Life's Essential 8 with abdominal aortic calcification and mortality among middle‐aged and older individuals
    Gehui Ni, Qinfeng Jia, Ying Li, Iokfai Cheang, Xu Zhu, Haifeng Zhang, Xinli Li
    Diabetes, Obesity and Metabolism.2024; 26(11): 5126.     CrossRef
  • Can smoking cause impotence? a radiological retrospective cohort study comparing internal pudendal artery calcification on CT in male smokers versus non-smokers
    Emma Tong, Caoimhe McDonnell, Kate Hunter, Kevin Sheahan, William C. Torreggiani
    Irish Journal of Medical Science (1971 -).2023; 192(1): 377.     CrossRef
  • Imaging Early Life Cardiovascular Phenotype
    Vinithra Varadarajan, Samuel S. Gidding, Colin Wu, J. Jeffrey Carr, Joao A.C. Lima
    Circulation Research.2023; 132(12): 1607.     CrossRef
  • Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells
    Ploingarm Petsophonsakul, Mathias Burgmaier, Brecht Willems, Sylvia Heeneman, Nadina Stadler, Felix Gremse, Sebastian Reith, Kathrin Burgmaier, Florian Kahles, Nikolaus Marx, Ehsan Natour, Elham Bidar, Michael Jacobs, Barend Mees, Chris Reutelingsperger,
    Cardiovascular Research.2022; 118(9): 2196.     CrossRef
  • Calcified Abdominal aortic occlusion: Treatment using Intravascular Lithotripsy
    Pratik Shah, Vimal Someshwar, Krishna Mundada, Abhijit Raut
    Journal of Clinical Interventional Radiology ISVIR.2022; 06(02): 141.     CrossRef
  • Relationship between blood cadmium and abdominal aortic calcification: NHANES 2013–2014
    Nuozhou Liu, Ying Feng, Yuejuan Zhan, Fang Ma
    Journal of Trace Elements in Medicine and Biology.2022; 72: 126975.     CrossRef
  • Prevalence and Predictors of Abdominal Aorta Calcification in Patients With Psoriasis—A Case Control Study
    Sofia Ramos, Sheetal Daya, Nigel J. Crowther, Lushen Pillay, Mohammed Tikly, Nasrin Goolam Mahyoodeen
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Association between body mass index and fragility fracture in postmenopausal women: a cross-sectional study using Korean National Health and Nutrition Examination Survey 2008–2009 (KNHANES IV)
    Jihan Kim, Sami Lee, Sung Soo Kim, Jong-Pyo Lee, Jong Sung Kim, Jin Gyu Jung, Seok Jun Yoon, Kyu Pil Kim, Chan-Keol Park, Yong-Hwan Kim
    BMC Women's Health.2021;[Epub]     CrossRef
  • Modified effect of active or passive smoking on the association between age and abdominal aortic calcification: a nationally representative cross-sectional study
    Luyan Lv, Shixian Wu, Yungui Yang, Xiongli Yue
    BMJ Open.2021; 11(10): e047645.     CrossRef
  • Association Between Serum Cotinine and Severe Abdominal Aortic Calcification in US Adults
    Xiaoxiao Wen, Yanjie Xia, Min Guo, Liancheng Zhao, Long Zhou
    Angiology.2020; 71(4): 333.     CrossRef
  • Role of Advanced Glycation End Products on Aortic Calcification in Patients with Type 2 Diabetes Mellitus
    Pilar Sanchis, Rosmeri Rivera, Regina Fortuny, Carlos Río, Miguel Mas-Gelabert, Marta Gonzalez-Freire, Felix Grases, Luis Masmiquel
    Journal of Clinical Medicine.2020; 9(6): 1751.     CrossRef
  • 5,297 View
  • 89 Download
  • 11 Web of Science
  • 13 Crossref
Association of Abdominal Aortic Calcification with Lifestyle and Risk Factors of Cardiovascular Disease
Eung-Du Kim, Jong Sung Kim, Sung-Soo Kim, Jin-Gyu Jung, Seok-Jun Yun, Ji-Young Kim, Jung-Sun Ryu
Korean J Fam Med 2013;34(3):213-220.   Published online May 24, 2013
DOI: https://doi.org/10.4082/kjfm.2013.34.3.213
Background

Abdominal aortic calcification (AAC) is a marker of subclinical atherosclerotic disease and an independent predictor of subsequent vascular morbidity and mortality. This study was conducted to investigate the association of AAC with lifestyle and risk factors of cardiovascular disease.

Methods

The results of the abdominal computed tomography of 380 patients who visited Chungnam National University Hospital for a health checkup from January 1, 2008 to December 31, 2009 were reviewed. A six-point scale was used in grading the overall severity of the calcification in three areas of the abdominal aorta, including the area superior to the renal artery, the upper-half area inferior to the renal artery, and the lower-half area inferior to the renal artery, in addition to the common iliac artery. The association of the AAC severity with the age, lifestyle factors, and risk factors of cardiovascular disease was analyzed via multiple linear regression analysis.

Results

In the male subjects, the age, presence of dyslipidemia and smoking were positively related to AAC, but exercising was negatively related to AAC (total R2 = 0.563). In the female subjects, the age and presence of diabetes mellitus, hypertension, and dyslipidemia were positively related to AAC, but exercising was negatively related to AAC (total R2 = 0.547).

Conclusion

AAC was related to both the male and female subjects' age, presence of dyslipidemia, and exercising, to smoking in the male subjects and to the presence of diabetes mellitus and hypertension in the female subjects.

Citations

Citations to this article as recorded by  
  • Associations between per- and polyfluoroalkyl chemicals and abdominal aortic calcification in middle-aged and older adults
    Jijingru Yang, Tian Wang, Kai Li, Yán Wāng
    Journal of Advanced Research.2025; 70: 203.     CrossRef
  • Association between oxidative balance scores and severe abdominal aortic calcification in American adults: National health and nutrition examination survey
    Liya Pan, Wujie Xia, Jing Song, Suqin Zhang
    Nutrition, Metabolism and Cardiovascular Diseases.2025; 35(2): 103697.     CrossRef
  • Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service
    Irma J. A. de Bruin, Caroline E. Wyers, Lisanne Vranken, John T. Schousboe, Robert Y. van der Velde, Heinrich M. J. Janzing, Frederik O. Lambers Heerspink, Piet P. M. M. Geusens, Joop P. van den Bergh
    Osteoporosis International.2025; 36(1): 103.     CrossRef
  • Evaluation of the relationship between visceral obesity and abdominal aorta calcified plaques with computed tomography
    İsmail Taşkent, Ali Küpeli
    Journal of Health Sciences and Medicine.2025; 8(1): 4.     CrossRef
  • Klotho mediates the association between serum testosterone and severe abdominal aortic calcification: a cross-sectional study from the NHANES database
    Shengwei Lai, Handai Qin, Xinhao Wang, Guanchao Sun, Long Cao, Zheqi Fan, Hongpeng Zhang, Wei Guo
    Naunyn-Schmiedeberg's Archives of Pharmacology.2025;[Epub]     CrossRef
  • Association between cardiovascular health and abdominal aortic calcification: Analyses of NHANES 2013–2014
    Sijie He, Li Wan, Yunyi Ding, Ya Zhang, Mingjiang Liu, Ruijie Xie
    International Journal of Cardiology.2024; 403: 131878.     CrossRef
  • Abdominal aortic calcification among gastroenterological and transplant surgery
    Yuki Imaoka, Masahiro Ohira, Miho Akabane, Kazunari Sasaki, Hideki Ohdan
    Annals of Gastroenterological Surgery.2024; 8(6): 987.     CrossRef
  • Association of Life's Essential 8 with abdominal aortic calcification and mortality among middle‐aged and older individuals
    Gehui Ni, Qinfeng Jia, Ying Li, Iokfai Cheang, Xu Zhu, Haifeng Zhang, Xinli Li
    Diabetes, Obesity and Metabolism.2024; 26(11): 5126.     CrossRef
  • The essential role of dual-energy x-ray absorptiometry in the prediction of subclinical cardiovascular disease
    Sisi Yang, Qin Chen, Yang Fan, Cuntai Zhang, Ming Cao
    Frontiers in Cardiovascular Medicine.2024;[Epub]     CrossRef
  • Study of the Association Between Diets Containing Nuts and Seeds and the Degree of Abdominal Aortic Calcification
    Larry A. Tucker
    Nutrients.2024; 16(24): 4325.     CrossRef
  • Imaging Early Life Cardiovascular Phenotype
    Vinithra Varadarajan, Samuel S. Gidding, Colin Wu, J. Jeffrey Carr, Joao A.C. Lima
    Circulation Research.2023; 132(12): 1607.     CrossRef
  • The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification
    Chang Sheng, Weihua Huang, Wei Wang, Guoqiang Lin, Mingmei Liao, Pu Yang
    Journal of Translational Medicine.2023;[Epub]     CrossRef
  • Massive Calcified Abdominal Aortic Aneurysm Presenting as Low Back Pain
    Oxana Ushakova, Keyvan Ravakhah
    Cureus.2023;[Epub]     CrossRef
  • Magnesium and Zinc Intake Ratio Mediates the Increase of Coronary Artery Calcification through Upregulating Interleukin 6
    Abdulhakim Al-Qaridhi, Sounak Ghosh, Dongling Luo, Hui Huang
    Libyan Journal of Medicine.2022;[Epub]     CrossRef
  • Abdominal aortic calcification is associated with Fibrosis‐4 index and low body mass index in type 2 diabetes patients: A retrospective cross‐sectional study
    Yu Togashi, Daisuke Miyashita, Takahiro Tsuno, Ryota Inoue, Tomoko Okuyama, Mayu Kyohara, Kuniyuki Nishiyama, Masanori Arai, Kenta Kanematsu, Soichiro Kanataki, Yasuo Terauchi, Jun Shirakawa
    Journal of Diabetes Investigation.2022; 13(11): 1861.     CrossRef
  • Abdominal aortic calcification in patients with inflammatory bowel disease: does anti-tumor necrosis factor α use protect from chronic inflammation-induced atherosclerosis?
    Aikaterini Mantaka, Nikolaos Galanakis, Dimitrios Tsetis, Ioannis E. Koutroubakis
    Intestinal Research.2022; 20(4): 495.     CrossRef
  • Abdominal aortic calcification: from ancient friend to modern foe
    Jonas W Bartstra, Willem P Th M Mali, Wilko Spiering, Pim A de Jong
    European Journal of Preventive Cardiology.2021; 28(12): 1386.     CrossRef
  • What Causes the Discrepancy between Quantitative Computed Tomography and Dual Energy X-Ray Absorptiometry?
    Hong Yoon, Jung-Ho Kim, Dal-Sung Ryu, Seung-Hwan Yoon
    The Nerve.2021; 7(2): 64.     CrossRef
  • Rapid Progression of Aortic Calcification in Older Men with Low Appendicular Lean Mass and Poor Physical Function
    Pawel Szulc, R. Chapurlat
    The Journal of nutrition, health and aging.2021; 25(10): 1217.     CrossRef
  • Evolution of Fibro-Calcific Plaque in Different Segments of the Pulmonary Trunk
    Kavita Pahuja, Amardeep Bissa
    Advances in Human Biology.2021; 11(2): 195.     CrossRef
  • CT-Based Evaluation of Diffuse Idiopathic Skeletal Hyperostosis in Adult Population; Prevalence, Associations and Interobserver Agreement
    Hatem Adel, Sohail Ahmed Khan, Syed Omair Adil, Farheen Huda, Usman Khanzada, Murli Manohar, Kamran Masood
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  • Relationship between Smoking and Abdominal Aorta Calcification on Computed Tomography
    Jin-Gyu Jung, Li-Tzy Wu, Jong-Sung Kim, Eung-Du Kim, Seok-Joon Yoon
    Korean Journal of Family Medicine.2019; 40(4): 248.     CrossRef
  • Relationship of Riboflavin and Niacin with Cardiovascular Disease
    Ji Yeong Ahn, In Sik Kim, Ji-Sook Lee
    The Korean Journal of Clinical Laboratory Science.2019; 51(4): 484.     CrossRef
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    Emilie Frey Bendix, Eskild Johansen, Thomas Ringgaard, Martin Wolder, Jakob Starup-Linde
    Current Osteoporosis Reports.2018; 16(1): 42.     CrossRef
  • Sex difference in the association of androgens with aortic calcification
    Tsuyoshi Hashizume, Bo‐Kyung Son, Taro Kojima, Michiko Nanao‐Hamai, Yusuke Asari, Yumi Umeda‐Kameyama, Sumito Ogawa, Masahiro Akishita
    Geriatrics & Gerontology International.2018; 18(7): 1137.     CrossRef
  • The impact of abdominal fat on abdominal aorta calcification measured on non-enhanced CT
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    Medicine.2018; 97(49): e13233.     CrossRef
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  • 4,786 View
  • 34 Download
  • 35 Crossref
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