• KAFM
  • Contact us
  • E-Submission
ABOUT
ARTICLE CATEGORY
BROWSE ARTICLES
AUTHOR INFORMATION

Page Path

5
results for

"Hyun-Young Shin"

Filter

Article category

Keywords

Publication year

Authors

Funded articles

"Hyun-Young Shin"

Clinical Practice Guideline

Clinical Practice Guidelines for Managing Frailty in Community-Dwelling Korean Elderly Adults in Primary Care Settings
Hyo-Sun You, Yu-Jin Kwon, Sunyoung Kim, Yang-Hyun Kim, Ye-seul Kim, Yonghwan Kim, Yong-kyun Roh, Byoungjin Park, Young Kyu Park, Chang-Hae Park, Joung Sik Son, Jinyoung Shin, Hyun-Young Shin, Bumjo Oh, Jae-woo Lee, Jae Yong Shim, Chang Won Won, Ji Won Yoo, Sang-Hyun Lee, Hee-Taik Kang, Duk Chul Lee
Korean J Fam Med 2021;42(6):413-424.   Published online November 20, 2021
DOI: https://doi.org/10.4082/kjfm.21.0162
Aging has become a global problem, and the interest in healthy aging is growing. Healthy aging involves a focus on the maintenance of the function and well-being of elderly adults, rather than a specific disease. Thus, the management of frailty, which is an accumulated decline in function, is important for healthy aging. The adaptation method was used to develop clinical practice guidelines on frailty management that are applicable in primary care settings. The guidelines were developed in three phases: preparation (organization of committees and establishment of the scope of development), literature screening and evaluation (selection of the clinical practice guidelines to be adapted and evaluation of the guidelines using the Korean Appraisal of Guidelines for Research and Evaluation II tool), and confirmation of recommendations (three rounds of Delphi consensus and internal and external reviews). A total of 16 recommendations (five recommendations for diagnosis and assessment, 11 recommendations for intervention of frailty) were made through the guideline development process. These clinical practice guidelines provide overall guidance on the identification, evaluation, intervention, and monitoring of frailty, making them applicable in primary care settings. As aging and “healthy aging” become more and more important, these guidelines are also expected to increase in clinical usefulness.

Citations

Citations to this article as recorded by  
  • Promoting an international consensus on frailty assessment: An urgent call to address the challenges of perioperative management in an aging population
    Ying Xia, Wei Tang
    BioScience Trends.2026;[Epub]     CrossRef
  • International landscape of guidelines for perioperative frailty assessment and barriers to clinical translation
    Ya-nan Ma, Kenji Karako, Ying Xia, Peipei Song, Xiqi Hu
    BioScience Trends.2026;[Epub]     CrossRef
  • Effect of a wearable-sensor-assisted multicomponent exercise program on physical fitness, cognition and quality of life in frail older adults
    Genghong Tu, Lining Liu, Huiyi Tang, Weizhong Chen, Bagen Liao
    Translational Exercise Biomedicine.2025; 2(3): 201.     CrossRef
  • Frailty assessment utilization around the globe–a systematic review
    Samantha Gaston, Elle Billman, Lichy Han, David Drover
    The Journal of Frailty & Aging.2025; 14(6): 100088.     CrossRef
  • Exercise Prescription for Frail Older Adults: Impact on Handgrip Strength and Gait Speed – A Systematic Review
    Andreia Carvalho, Vânia Cerqueira Palma, Maria Teresa Tomás
    Physical & Occupational Therapy In Geriatrics.2025; : 1.     CrossRef
  • Summary of best evidence for prevention and management of frailty
    Yinning Guo, Xueyi Miao, Jieman Hu, Li Chen, Yimeng Chen, Kang Zhao, Ting Xu, Xiaoman Jiang, Hanfei Zhu, Xinyi Xu, Qin Xu
    Age and Ageing.2024;[Epub]     CrossRef
  • Frailty: Assessment and Intervention
    Hana Moon, Geon Ho Lee, DaeHyun Kim
    Keimyung Medical Journal.2024; 43(2): 100.     CrossRef
  • Clinical practice guidelines for frailty vary in quality but guide primary health care: a systematic review
    Huaxin Si, Jiaqi Yu, Qinqin Liu, Yanyan Li, Yaru Jin, Yanhui Bian, Xiaoxia Qiao, Wenyu Wang, Lili Ji, Yan Wang, Jian Du, Cuili Wang
    Journal of Clinical Epidemiology.2023; 161: 28.     CrossRef
  • Yaşlılarda Kırılganlığın Önlenmesi ve Yönetiminde Kanıta Dayalı Yaklaşımlar
    Ayşe Buket DOĞAN, Özlem CANBOLAT
    Sağlık Bilimlerinde Değer.2023; 13(3): 501.     CrossRef
  • Validation of the Korean Academy of Geriatric Dentistry screening questionnaire and oral frailty diagnostic criteria in community-dwelling older adults
    Jeong-Hyun Kang, Seong-Chan Park, Hoi-In Jung, Sun Jae Jung, Hye-Jin Park, Soo-Min Kim, Min-Ji Jo, Yun-Seon Lee, Sun-Young Han
    Epidemiology and Health.2023; 46: e2024008.     CrossRef
  • Up-to-date knowledge of frailty
    Chang Won Won
    Journal of the Korean Medical Association.2022; 65(2): 108.     CrossRef
  • Current status of nutrient intake in Korea: focused on macronutrients
    Seung-Won Oh
    Journal of the Korean Medical Association.2022; 65(12): 801.     CrossRef
  • 11,861 View
  • 226 Download
  • 10 Web of Science
  • 12 Crossref
Original Articles
Background
Several studies have suggested that breastfeeding has a positive effect on long-term obesity, diabetes, hypertension, and hyperlipidemia. This study aimed to examine maternal bone health, muscle mass, and obesity based on breastfeeding duration.
Methods
This study was based on the Korea National Health and Nutrition Examination Survey 2010–2011. We selected 2,027 elderly women by screening survey participants with a history of delivery. Multivariate logistic regression analyses were performed to estimate the odds ratios (ORs) of sarcopenia, osteoporosis, and obesity among four breastfeeding groups.
Results
The OR of sarcopenia significantly decreased with increasing breastfeeding duration (OR, 0.27; 95% confidence interval [CI], 0.11–0.65; P for trend <0.001), whereas the OR of obesity significantly increased with increasing breastfeeding duration (OR, 2.56; 95% CI, 1.43–4.60; P for trend=0.009) after adjusting for potential confounding variables. We also found a positive correlation between the duration since last delivery and sarcopenia.
Conclusion
Our results suggest a negative correlation between prolonged breastfeeding and the prevalence of sarcopenia, and a positive correlation between prolonged breastfeeding and the prevalence of obesity. Further studies are needed to clarify the relationship between breastfeeding and sarcopenia in the future.

Citations

Citations to this article as recorded by  
  • Association of breastfeeding duration with longitudinal changes in vertebral bone marrow, paraspinal muscle composition, and metabolic parameters in premenopausal women over five years
    N. Hesse, Y. Stohldreier, S. Schlaeger, S. Theuerl, O. Dietrich, H. Hermann, I. Kaiser, J. Seissler, E. Pappa, U. Ferrari, A.S. Gersing
    European Journal of Radiology.2026; 195: 112514.     CrossRef
  • Interventions and Programs to Promote Breastfeeding in Arabic-Speaking Countries: A Scoping Review
    Basil H. Aboul-Enein, Elizabeth Dodge, Nada Benajiba, Ruth M. Mabry
    Maternal and Child Health Journal.2023; 27(5): 774.     CrossRef
  • Breastfeeding Duration Is Associated with the Risk of Tooth Loss, Chewing Difficulty, and Undernutrition among Older Korean Women: Results of the Korea National Health and Nutrition Examination Survey (KNHANES) 2013–2015
    Ye Rang Jo, Yoo Kyoung Park, Hee-Sook Lim
    Nutrients.2023; 15(24): 5024.     CrossRef
  • Association of total lifetime breastfeeding duration with midlife handgrip strength: findings from Project Viva
    Irasema C. Paster, Pi-i D. Lin, Sheryl L. Rifas-Shiman, Wei Perng, Jorge E. Chavarro, Emily Oken
    BMC Women's Health.2022;[Epub]     CrossRef
  • Breastfeeding and Sarcopenia in Later Life
    Jungun Lee
    Korean Journal of Family Medicine.2019; 40(3): 133.     CrossRef
  • 8,507 View
  • 122 Download
  • 5 Web of Science
  • 5 Crossref
Background

We investigated the association between socioeconomic status and adherence to health check-ups in a Korean population aged 40 years or older.

Methods

This cross-sectional study included 12,311 participants who participated in the 2010–2012 Korean National Health and Nutrition Examination Survey. Self-reported questionnaires were used to assess each participant's socioeconomic status (household income, occupation, and education) and adherence to health check-ups.

Results

Men with a higher income (highest vs. lowest: odds ratio [OR], 1.799; 95% confidence interval [CI], 1.296–2.497) and men with a higher education level (≥12 vs. <6 years: OR, 1.488; 95% CI, 1.078–2.054) and office workers compared with manual workers (men: OR, 1.431; 95% CI, 1.077–1.902; women: OR, 1.783; 95% CI, 1.256–2.532) appeared to undergo more health check-ups. In particular, men and women with a higher income and education appeared more likely to undergo opportunistic health check-ups (men: highest vs. lowest income: OR, 2.380; 95% CI, 1.218–4.653; ≥12 vs. <6 years education: OR, 2.121; 95% CI, 1.142–3.936; women: highest vs. lowest income: OR, 4.042; 95% CI, 2.239–7.297; ≥12 vs. <6 years education: OR, 2.475; 95% CI, 1.283–4.775).

Conclusion

A higher socioeconomic status was associated with a higher rate of participation in health check-ups. More efforts are needed to identify the factors associated with disparity in adherence to health check-ups.

Citations

Citations to this article as recorded by  
  • Development of a machine learning model for hepatic steatosis screening using non-invasive Traditional Chinese Medicine diagnostics and clinical variables: a health checkup study with community screening potential
    Ke Zhu, Lihua Li, Zhihui Zhao, Sheng Zheng, Bing Lin, Wenjun Tang, Weihong Li
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • Income-related disparities in sudden cardiac arrest among young adults: a nationwide cohort study
    Joo Hee Jeong, Kyung-Do Han, Seung-Young Roh, Chang-Ok Seo, Hyoung Seok Lee, Yun Gi Kim, Jaemin Shim, Young-Hoon Kim, Jong-Il Choi
    Heart.2026; : heartjnl-2025-326763.     CrossRef
  • Cancer incidence near nuclear facilities in Korea (2005–2022): implications of regional socioeconomic status and industrial context
    Ga Bin Lee, Kyungsik Kim, Eun-Shil Cha, Soojin Park, Dalnim Lee, Minsu Cho, Sue K. Park, Songwon Seo
    BMC Public Health.2026;[Epub]     CrossRef
  • Socioeconomic Status and Self-Rated Health in Older Adults with Disabilities: A Mediation Analysis of Reserve Capacity Using the Korea Welfare Panel Study
    Sanghyun Park, Joonhee Ahn
    Social Sciences.2026; 15(2): 144.     CrossRef
  • Long-term impact of socioeconomic status after acute myocardial infarction in Korea
    Hoyoun Won, Yong-Hoon Kim, Jeongsook Kim, Yonghwan Kim, Hee-Taik Kang
    Nutrition, Metabolism and Cardiovascular Diseases.2025; 35(3): 103729.     CrossRef
  • Exploring pharmacy students’ comfort levels with peer-conducted blood pressure examinations
    Fahamina Ahmed, Meva Beganovic, Fatima Zeini, Candice Smith, Amne Borghol
    Discover Education.2025;[Epub]     CrossRef
  • Predictors of vision screening among Saudis at primary healthcare settings in Riyadh, Saudi Arabia: findings from a cross-sectional survey
    Ashraf Elmetwally, Mamdouh Shubair, Ibtehaj Alshdoukhi, Rasha Alhazzaa, Faris Fatani, Aljohrah Aldubikhi, Dr Badr Alkhateeb, Naif Alhawiti, Raed Aldahash, Jumanaa Masoudi, Hanan Al Kadri
    PeerJ.2025; 13: e20239.     CrossRef
  • Association between the utilization of senior centers and participation in health check-ups
    Ah Jung Ko, Jinhyun Kim, Eun-Cheol Park, Min Jin Ha
    Scientific Reports.2024;[Epub]     CrossRef
  • Body mass index is associated with clinical outcomes in idiopathic pulmonary fibrosis
    Hee-Young Yoon, Hoseob Kim, Yoonjong Bae, Jin Woo Song
    Scientific Reports.2024;[Epub]     CrossRef
  • Association between life satisfaction, self-esteem, and health checkup participation: A population-based longitudinal study in South Korea
    Seong-Uk Baek, Jin-Ha Yoon
    Preventive Medicine.2024; 189: 108127.     CrossRef
  • Risk Factors Associated With a Large Vertical Cup-to-Disc Ratio: Korean National Health and Nutritional Examination Survey
    Moon Hyung Lee, Hong Kyu Kim, Sung Soo Kim
    Journal of Glaucoma.2023; 32(3): 221.     CrossRef
  • Impact of health disparities on national breast cancer screening participation rates in South Korea
    Fatima Nari, Juwon Park, Nayeon Kim, Dong Jin Kim, Jae Kwan Jun, Kui Son Choi, Mina Suh
    Scientific Reports.2023;[Epub]     CrossRef
  • Socioeconomic Disparities in the Association Between All-Cause Mortality and Health Check-Up Participation Among Healthy Middle-Aged Workers: A Nationwide Study
    Byungyoon Yun, Juyeon Oh, Jaesung Choi, Laura S. Rozek, Heejoo Park, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Factors associated with awareness and passage of medical screening in hypertensive persons: data from the Know Your Heart study
    M. I. Kashutina, A. V. Kontsevaya, A. V. Kudryavtsev, S. K. Malyutina, P. V. Ipatov, O. M. Drapkina
    Cardiovascular Therapy and Prevention.2022; 21(3): 3156.     CrossRef
  • Letter: cervicocerebral atherosclerosis and its hepatic and coronary risk factors in patients with liver cirrhosis
    Yi-Chun Huang, Chih-Wei Chen, James Chun-Chung Wei
    Clinical and Molecular Hepatology.2022; 28(2): 265.     CrossRef
  • Current Status of the National Health Screening Programs in South Korea
    Hee-Taik Kang
    Korean Journal of Family Medicine.2022; 43(3): 168.     CrossRef
  • The Effect of Health Check-Ups on Health Among the Elderly in China: Evidence From 2011–2018 Longitudinal Data
    Dantong Zhao, Zhongliang Zhou, Chi Shen, Xiaohui Zhai, Yaxin Zhao, Dan Cao, Qiwei Deng, Guanping Liu, Jeremy Fung Yen Lim
    International Journal of Public Health.2022;[Epub]     CrossRef
  • Effect of income level on stroke incidence and the mediated effect of simultaneous diagnosis of metabolic syndrome diseases; a nationwide cohort study in South Korea
    Seungmin Jeong, Sung-il Cho, So Yeon Kong
    Diabetology & Metabolic Syndrome.2022;[Epub]     CrossRef
  • The Association between New-Onset Depressive Symptoms and Participating in Medical Check-Ups among Elderly Individuals
    Heejoo Park, Juho Sim, Juyeon Oh, Jongmin Lee, Chorom Lee, Yangwook Kim, Byungyoon Yun, Jin-ha Yoon
    International Journal of Environmental Research and Public Health.2022; 19(18): 11509.     CrossRef
  • Effect of Income Level on Stroke Incidence and Mediated Effects of Medication Adherence in Newly Diagnosed Hypertensive Patients: A Causal Mediation Analysis Using a Nationwide Cohort Study in South Korea
    Seungmin Jeong, So Yeon Kong, Seung-sik Hwang, Sung-il Cho
    Journal of Health Informatics and Statistics.2022; 47(4): 268.     CrossRef
  • Factors related to mammography adherence among women in Brazil: A scoping review
    Camila Brasil Moreira, V. Susan Dahinten, A. Fuchsia Howard, Ana Fátima Carvalho Fernandes, Janine Schirmer
    Nursing Open.2021; 8(5): 2035.     CrossRef
  • Adherence Improvement in Glaucoma Patients: Effects of Educational Intervention Using an Eye Drop Chart
    Woo Seok Choi, Jong Heon Kim, Chang Hoon Lee, Chong Eun Lee, Sam Seo
    Journal of the Korean Ophthalmological Society.2021; 62(12): 1617.     CrossRef
  • Association between nutrients and metabolic syndrome in middle-aged Korean women
    Sul Lee, Hyun Joo Lee, Seung Chul Kim, Jong Kil Joo
    Archives of Endocrinology and Metabolism.2020; 64(3): 298.     CrossRef
  • Pure Tone Audiometry Threshold Changes for 10 Years in the Same Individuals of General Population: A Retrospective Cohort Study
    Hantai Kim, Jungho Ha, Hun Yi Park
    Annals of Otology, Rhinology & Laryngology.2019; 128(5): 433.     CrossRef
  • Eye Drop Chart for Improvement of Topical Eye Drops Administration and Adherence
    Kyu Young Shim, Sam Seo, Soo Jin Lee, Chong Eun Lee
    Journal of the Korean Ophthalmological Society.2019; 60(2): 160.     CrossRef
  • Importance of Opportunistic Health-Checks among Lower Socioeconomic Groups
    Hyun S. Lee
    Korean Journal of Family Medicine.2019; 40(3): 199.     CrossRef
  • Associations of occupation, employment type and company size with actions related to health examinations among Japanese employees
    Rumi SEKO, Miyuki KAWADO, Sayana SAITO, Takuma SHIBUYA, Miho MIYAMOTO, Hiroya YAMADA, Hiroshige TANIWAKI, Shuji HASHIMOTO
    Industrial Health.2019; 57(4): 537.     CrossRef
  • Health Inequality in Health Checkups
    Jungun Lee
    Korean Journal of Family Medicine.2018; 39(2): 65.     CrossRef
  • Impact of Socioeconomic Status on 30-Day and 1-Year Mortalities after Intensive Care Unit Admission in South Korea: A Retrospective Cohort Study
    Tak Kyu Oh, Jihoon Jo, Young-Tae Jeon, In-Ae Song
    Acute and Critical Care.2018; 33(4): 230.     CrossRef
  • 11,805 View
  • 85 Download
  • 29 Web of Science
  • 29 Crossref
Mental Health of the People with Hearing Impairment in Korea: A Population-Based Cross-Sectional Study
Hyun-Young Shin, Hee-Jin Hwang
Korean J Fam Med 2017;38(2):57-63.   Published online March 22, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.2.57
Background

The prevalence of hearing impairment is increasing and an association between hearing impairment and mental health has been reported. Our study aimed to determine the association between hearing impairment and mental health in Korea.

Methods

This was a cross-sectional study of data from the Korean National Health and Nutrition Examination Survey 2010–2013, with a sample size of 18,563 individuals (6,395 with hearing impairment and 12,168 without hearing impairment), aged ≥20 years.

Results

The female group with hearing impairment tended to have a higher rate of stress (odds ratio [OR], 1.32; 95% confidence interval [CI], 1.11 to 1.56). The association between hearing impairment and depressive symptoms was higher in elderly males (OR, 1.60; 95% CI, 1.10 to 2.32), while the association of hearing impairment with suicide ideation was higher in elderly females (OR, 1.32; 95% CI, 1.00 to 1.75).

Conclusion

Elderly individuals with hearing impairment are easily susceptible to poor mental health status. Early targeted intervention to address mental health problems is recommended for people with hearing impairment.

Citations

Citations to this article as recorded by  
  • The Relationship Between Self-Reported Hearing Loss and Depression Among Older Adults: The Moderating Effect of Digital Device Use
    Jayeong Kim, Yeji Hwang
    Clinical Gerontologist.2026; 49(1): 206.     CrossRef
  • Suicidality in Individuals With Hearing Loss: A Systematic Review and Meta‐Analysis
    Isabelle J. Chau, Anuja H. Shah, Shaun A. Nguyen, Habib G. Rizk, Robert F. Labadie, Ted A. Meyer
    Otolaryngology–Head and Neck Surgery.2026; 174(3): 613.     CrossRef
  • Executive functions and cognitive emotion regulation in adults with deaf and hard-of-hearing: The mediating role of quality of life
    Ghithan Saleh Alamri
    Applied Neuropsychology: Adult.2026; : 1.     CrossRef
  • Effect of Emotional Intelligence on the General Health and Life Orientation of Adolescents Who Have a Hearing Impairment
    Mohammad Ashori
    International Journal of Disability, Development and Education.2025; 72(2): 282.     CrossRef
  • Association of hearing loss with cognitive function and mental health in Africa: A systematic review
    Abdulazeez Ahmed, Fatimah Tsiga-Ahmed, Nafisatu Bello-Muhammad, Abdulrazaq Ajiya, Mustapha Gudaji, Denes Stefler
    BMC Public Health.2025;[Epub]     CrossRef
  • Gender-specific relationships between hearing loss, its rehabilitation, and quality of life in middle-aged and older adults
    Sang-Yoon Han, Soomi Choi, Young Ho Kim
    Acta Oto-Laryngologica.2025; 145(11): 1019.     CrossRef
  • Emotional intelligence: Behavioral emotion regulation and health-related quality of life in students with hearing loss
    Mohammad Ashori, Seyyedeh Somayyeh Jalil-Abkenar
    Current Psychology.2024; 43(3): 2124.     CrossRef
  • Effect of cognitive remediation on cognitive and behavioral emotion regulation of female deaf and hard-of-hearing students
    Mohammad Ashori
    Current Psychology.2024; 43(10): 8740.     CrossRef
  • Association between hearing loss and suicidal ideation: Discrepancy between pure tone audiometry and subjective hearing level
    Jeong Hyun Ahn, Ji Su Yang, Jinsei Jung, Sunghyuk Kang, Sun Jae Jung
    Journal of Affective Disorders.2024; 344: 495.     CrossRef
  • Effects of emotion regulation training on social problem-solving in hard-of-hearing adolescents
    Mehrshid Danadel, Mohammad Ashori
    Current Psychology.2024; 43(17): 15366.     CrossRef
  • Association of sensory impairment with cognitive function and mental health among the older adults in China
    Lele Chen, Renlai Zhou
    Current Psychology.2023; 42(18): 15061.     CrossRef
  • Association Between Hearing Impairment and Incident Depression: A Nationwide Follow‐up Study
    Hye Jun Kim, Seogsong Jeong, Kyung Jin Roh, Yun Hwan Oh, Michelle J. Suh
    The Laryngoscope.2023; 133(11): 3144.     CrossRef
  • Association between hearing loss and suicidal ideation among middle-aged and older adults
    Junghyun Park, Othelia Lee, Michael McKee
    Aging & Mental Health.2022; 26(6): 1287.     CrossRef
  • Visual and hearing impairment and their association with depression among middle‐aged and older individuals in India: Evidence from a cross‐sectional study
    Trupti Meher, Shivani Gharge
    International Journal of Geriatric Psychiatry.2022;[Epub]     CrossRef
  • The effectiveness of group play therapy with cognitive-behavioral approach on anxiety and social skills of deaf students
    Ahmad Mahmoodi, Maryam Mashayekh, Fatemeh Zam, Mehdi Shahnazari, Javid Peymani
    Alborz University Medical Journal.2022; 12(1): 23.     CrossRef
  • İşitme Kayıplı Yetişkinlerde Sosyal Kaygı ve Saldırganlık Arasındaki İlişkinin Araştırılması
    Mert Kılıç, Filiz Yağcı, Zahra Polat
    Hacettepe University Faculty of Health Sciences Journal.2022; 9(2): 344.     CrossRef
  • Emotional intelligence: Quality of life and cognitive emotion regulation of deaf and hard-of-hearing adolescents
    Mohammad Ashori, Seyyedeh Somayyeh Jalil-Abkenar
    Deafness & Education International.2021; 23(2): 84.     CrossRef
  • Risk of new-onset depressive disorders after hearing impairment in adults: A nationwide retrospective cohort study
    Jae Woo Choi, Euna Han
    Psychiatry Research.2021; 295: 113351.     CrossRef
  • Age and sex differences in hearing loss association with depressive symptoms: analyses of NHANES 2011–2012
    Franco Scinicariello, Jennifer Przybyla, Yulia Carroll, John Eichwald, John Decker, Patrick N. Breysse
    Psychological Medicine.2019; 49(6): 962.     CrossRef
  • Depressive and Anxiety Symptoms in Older Adults With Auditory, Vision, and Dual Sensory Impairment
    Adam Simning, Meghan L. Fox, Steven L. Barnett, Silvia Sorensen, Yeates Conwell
    Journal of Aging and Health.2019; 31(8): 1353.     CrossRef
  • A Review of Hearing Loss Associated with Zika, Ebola, and Lassa Fever
    Samuel C. Ficenec, John S. Schieffelin, Susan D. Emmett
    The American Journal of Tropical Medicine and Hygiene.2019; 101(3): 484.     CrossRef
  • 19,709 View
  • 68 Download
  • 25 Web of Science
  • 21 Crossref
Adiponectin in Women with Polycystic Ovary Syndrome
Hyun-Young Shin, Duk-Chul Lee, Ji-Won Lee
Korean J Fam Med 2011;32(4):243-248.   Published online May 31, 2011
DOI: https://doi.org/10.4082/kjfm.2011.32.4.243
Background

Though adiponectin has been associated with insulin resistance and cardiovascular risk factors, the relationship between adiponectin and polycystic ovary syndrome (PCOS) remains controversial. The aim of this study was to compare adiponectin level in women with PCOS and without PCOS, and to investigate the relationship between adiponectin level and metabolic variables including insulin resistance.

Methods

60 women with PCOS were enrolled along with a control group of 80 healthy women, matched for age and body mass index (BMI). We measured hormonal and metabolic parameters, as well as the plasma adiponectin concentration of each participant. We estimated the insulin sensitivity according to the quantitative insulin sensitivity check index (QUICKI).

Results

The PCOS group displayed significantly lower level of adiponectin (P < 0.001) after adjustment for age, BMI, mean blood pressure, fasting glucose, fasting insulin, and several metabolic parameters. Adiponectin levels were positively correlated with QUICKI in the PCOS group (P < 0.001) and the control group (P = 0.03). Following step-wise multiple regression analysis, however, adiponectin level was positively correlated with QUICKI in the control group only (P = 0.03). In addition, adiponectin level was found to be independently associated with HDL-cholesterol level (P < 0.001) and BMI (P = 0.02) in the PCOS group and independently associated with HDL-cholesterol (P = 0.02) in the control group.

Conclusion

We report decreased adiponectin level in PCOS patients in relation to controls independently of insulin resistance or other metabolic factors. And adiponectin is associated with both lipid metabolism and obesity, which, in turn, is related to insulin resistance in PCOS. Further studies are needed to clarify the mechanism of adiponectin in PCOS.

Citations

Citations to this article as recorded by  
  • Evaluation of serum adiponectin as a marker of insulin resistance in women with polycystic ovarian syndrome: a comparative cross-sectional study
    Olugbenga Ojatokunbo Runsewe, Abiodun Adeniyi Adewunmi, Gbenga Olorunfemi, Abimbola Tawaqualit Ottun, Ayokunle Moses Olumodeji, Babalola Ogungbemile, Tamramat Iyabo Runsewe-Abiodun
    Reproductive Biology and Endocrinology.2024;[Epub]     CrossRef
  • A Study of Serum Adiponectin Levels in Patients with Polycystic Ovarian Syndrome and its Correlation with Various Cardiometabolic Risk Markers
    G. Surendra Prasad, Uma Kaimal Saikia, Ashok Krishna Bhuyan, Abhamoni Baro
    Journal of Human Reproductive Sciences.2023; 16(4): 299.     CrossRef
  • Influence of hsCRP Parameter on the Occurrence of Metabolic Syndrome in Patients with Polycystic Ovary Syndrome
    Katarzyna Lejman-Larysz, Dominika Pietrzyk, Adrianna Ćwiertnia, Mateusz Kozłowski, Sebastian Kwiatkowski, Iwona Szydłowska, Jolanta Nawrocka-Rutkowska, Jacek Brodowski, Elżbieta Sowińska-Przepiera, Aneta Cymbaluk-Płoska, Agnieszka Brodowska
    Biomedicines.2023; 11(7): 1953.     CrossRef
  • Markers of insulin resistance in Polycystic ovary syndrome women: An update
    Chantal Anifa Amisi
    World Journal of Diabetes.2022; 13(3): 129.     CrossRef
  • Plasma Complement C1q/tumor necrosis factor-related protein 15 concentration is associated with polycystic ovary syndrome
    Akram Vatannejad, Reza Fadaei, Fouzieh Salimi, Fatima Zahraa Fouani, Behnam Habibi, Somayeh Shapourizadeh, Samira Eivazi, Sadegh Eivazi, Asie Sadeghi, Nariman Moradi, Clemens Fürnsinn
    PLOS ONE.2022; 17(6): e0263658.     CrossRef
  • Serum visfatin and adiponectin – markers in women with polycystic ovarian syndrome
    Doddappa Mallappa Bannigida, Shivananda B. Nayak, Vijayaragavan R.
    Archives of Physiology and Biochemistry.2020; 126(4): 283.     CrossRef
  • Systemic adiponectin treatment reverses polycystic ovary syndrome-like features in an animal model
    Anusha Singh, Puran Bora, Amitabh Krishna
    Reproduction, Fertility and Development.2018; 30(4): 571.     CrossRef
  • The preliminary association study of ADIPOQ, RBP4, and BCMO1 variants with polycystic ovary syndrome and with biochemical characteristics in a cohort of Polish women
    Ewa Czeczuga-Semeniuk, Marzenna Galar, Katarzyna Jarząbek, Piotr Kozłowski, Nela A. Sarosiek, Sławomir Wołczyński
    Advances in Medical Sciences.2018; 63(2): 242.     CrossRef
  • Lower circulating levels of CTRP12 and CTRP13 in polycystic ovarian syndrome: Irrespective of obesity
    Mehrnoosh Shanaki, Nariman Moradi, Reza Fadaei, Zahra Zandieh, Parisa Shabani, Akram Vatannejad, Andrew Wolfe
    PLOS ONE.2018; 13(12): e0208059.     CrossRef
  • The high-molecular weight multimer form of adiponectin is a useful marker of polycystic ovary syndrome in Bahraini Arab women
    Amina M. Al-Awadi, Sameh Sarray, Mona R. Arekat, Layal R. Saleh, Naeema Mahmood, Wassim Y. Almawi
    Clinical Nutrition ESPEN.2016; 13: e33.     CrossRef
  • Focus on metabolic and nutritional correlates of polycystic ovary syndrome and update on nutritional management of these critical phenomena
    Mariangela Rondanelli, Simone Perna, Milena Faliva, Francesca Monteferrario, Erica Repaci, Francesca Allieri
    Archives of Gynecology and Obstetrics.2014; 290(6): 1079.     CrossRef
  • Low circulating adiponectin levels in women with polycystic ovary syndrome: an updated meta-analysis
    Shan Li, Xiamei Huang, Huizhi Zhong, Qiliu Peng, Siyuan Chen, Yantong Xie, Xue Qin, Aiping Qin
    Tumor Biology.2014; 35(5): 3961.     CrossRef
  • Adipokines in reproductive function: a link between obesity and polycystic ovary syndrome
    Xinwang Chen, Xiao Jia, Jie Qiao, Youfei Guan, Jihong Kang
    Journal of Molecular Endocrinology.2013; 50(2): R21.     CrossRef
  • 5,435 View
  • 24 Download
  • 13 Crossref
TOP