Korean Journal of Family Medicine

Changes in Diagnostic Performance of Thyroid Cancer Screening before and after the Korean Thyroid Imaging Reporting and Data System Revision: Na Hyun Kim, Jong Soo Han, Woo Kyung Bae, Joo Young Kim, Kiheon Lee, Hyejin Lee, Kee Hyuck Lee, Se Young Jung, HanKyung Lee, Hee-Yeong Jeong, Young A Kim, Suyoun Sim, Ji-Won Kang; Korean J Fam Med 2022;43(4):225-230. Published online July 19, 2022; DOI: https://doi.org/10.4082/kjfm.21.0168

Abstract
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Background
Since the era of “thyroid cancer epidemic,” many Korean academic societies discouraged the use of ultrasonography in healthy individuals and revised the Korean Thyroid Imaging Reporting and Data System to address the overscreening and overdiagnosis issues. This study aimed to evaluate the change in the diagnostic effectiveness of thyroid cancer screening over the last decade.
Methods
This single-center, retrospective observational study analyzed the data of 125,962 thyroid nodules obtained during cancer screening at the health promotion center of Seoul National University Bundang Hospital from 2010 to 2019. Only 327 thyroid cancer cases pathologically confirmed by fine-needle aspiration (FNA) were included in the study. The strength of the association between the number of FNA and (1) the number of thyroid cancer diagnoses, (2) the positive predictive values (PPVs), and (3) the difference in PPV from the previous year were evaluated using Pearson’s correlation analysis.
Results
The number of thyroid FNA biopsies as well as the thyroid cancer diagnoses decreased from 2010 to 2019 (166 to 48 [-71.1%] vs. 43 to 22 [-48.8%]). The PPV of FNA biopsies increased from 25.9% to 45.8% (+76.8%) and was negatively correlated with the number of FNA biopsies performed (R=-0.87, P<0.001). The difference in PPV from the previous year increased similarly but without statistical significance (R=-0.59, P=0.09).
Conclusion
The diagnostic efficiency of thyroid cancer screening has increased over the last decade, as evidenced by the increasing PPV of FNA biopsies.

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Global trends and socioeconomic disparities in cancer burden among adolescents and young adults, 1990–2021
Runhua Li, Stephanie F. Smith, Flavia Pennisi, Eun-Hye Park, Lingbin Du
International Journal of Surgery.2026;[Epub] CrossRef
Impact of Incretin Mimetics on Thyroid Cancer Among Patients with Type 2 Diabetes: A Retrospective Cohort Time-to-Event Analysis
Michael W. Strand, Daniel Chow, Weining Shen, Jonathan H. Watanabe
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Fruit Intake and Changes of Cardio-Metabolic Risk Factors in People with Obesity: Shiao Shih Liu, Ju Young Kim, Jung Ha Park, Sohye Kim, Kiheon Lee, Woo Kyung Bae, Kee Hyuck Lee, Jong Soo Han, Hyejin Lee, Se Young Jung; Korean J Fam Med 2021;42(5):382-389. Published online September 20, 2021; DOI: https://doi.org/10.4082/kjfm.20.0205

Abstract
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Background
This study aimed to explore the relationship between fruit intake, changes in fruit intake, and changes in cardiometabolic factors in people with obesity.
Methods
A total of 21,270 subjects (8,718 men, 12,552 women) aged 40 years and over, from the Korean-based Genome and Epidemiology Study, were followed up for an average of 4.4 years. Fruit intake was assessed using a food frequency questionnaire at baseline and the second follow-up. The beta coefficient and confidence intervals for changes in cardiometabolic risk factors according to fruit consumption were calculated using a linear regression model.
Results
In men, the abdominal circumference decreased with changes in fruit intake (P=0.029). Fruit intake and increased fruit intake in men were associated with a lower systolic blood pressure (P=0.012 and P=0.02, respectively) and lower triglyceride levels (P=0.002 and P<0.001, respectively). In women, abdominal circumference decreased with both fruit intake and increased fruit intake (P<0.001 and P=0.013, respectively). Systolic blood pressure and triglycerides tended to decrease only with fruit intake (P=0.048 and P<0.001, respectively). Unlike in men, fasting blood glucose tended to decrease in women with both fruit intake and increased fruit intake (P=0.011 and P=0.005, respectively).
Conclusion
Fruit intake and increased fruit intake may have beneficial effects on cardiometabolic risk factors among individuals who are obese.

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Associations of cMIND Diet with depressive and anxiety symptoms among old people in China: a nationwide study
Tengfei Niu, Yu Zhang, Xilin Zhou, Kun Shen, Xinyan Ji, Juan Zhu, Ouxiang Wu, Xiaobing Xian
European Journal of Nutrition.2025;[Epub] CrossRef
Fruits and the Risk of Type 2 Diabetes: The Korean Genome and Epidemiology Study Cohort
Hojun Yu, Cheol Min Lee, Seung-Won Oh
Korean Journal of Family Medicine.2024; 45(1): 44. CrossRef
Association between cMIND diet and hypertension among older adults in China: a nationwide survey
Yazhu Wang, Yu Zhang, Xinrong Zeng, Xiaobing Xian, Jingyu Chen, Tengfei Niu
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Impact of fruits and vegetables consumption on metabolic health: a case–control study
Azza Abd El-Shaheed, Nermine N. Mahfouz, May M. Abdel Hamid
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Effects of Semaglutide on Cardiac Protein Expression and Cardiac Function of Obese Mice
Xiaoyu Pan, Lin Yue, Jiangli Ban, Lin Ren, Shuchun Chen
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Current status of nutrient intake in Korea: focused on macronutrients
Seung-Won Oh
Journal of the Korean Medical Association.2022; 65(12): 801. CrossRef
Current status of health promotion in Korea
Soo Young Kim
Journal of the Korean Medical Association.2022; 65(12): 776. CrossRef

7,604 View
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Risk Factors of Cardiovascular Disease according to Alcohol Behavioral Change after Cancer Diagnosis: Eun Mi Bae, In Young Cho, Ji-Hye Jun, Kiheon Lee, Ju Young Kim, Woo Kyung Bae, Hyejin Lee, Jong Soo Han, Se Young Jung, Kee Hyuck Lee, Sarah Kim, Hye Yeon Koo, Sang Jin Cho, Houbuem Lee, Chuelmin Paek; Korean J Fam Med 2020;41(4):222-228. Published online April 22, 2020; DOI: https://doi.org/10.4082/kjfm.18.0119

Background
Problem drinking increases the incidence of all-cause mortality and specific cancers, and persistent drinking is associated with cardiovascular disease in certain cancer survivors. This study analyzed the cardiovascular risk factors before and after diagnosis in Korean cancer survivors.
Methods
Data for the period between 2002 and 2013 were collected from the National Health Insurance Service Health-Examinee Cohort Database. Among the 27,835 patients included, those with moderate alcohol consumption before and after cancer diagnosis were excluded. Problem drinking was defined as males under 65 years consuming over 14 glasses a week, and males over 65 years or females consuming over seven glasses a week. A t-test, chi-square test, and linear regression analysis were performed for differences in cardiovascular risk factors and differences according to cancer types.
Results
There was a difference in the body mass index, systolic and diastolic blood pressure, and total cholesterol among patients who became moderate drinkers after diagnosis, but fasting blood glucose did not show any significant changes. Risk factors for cardiovascular disease were analyzed in patients with liver, stomach, rectal, and breast cancer with improved drinking behavior, and there were significant differences in body mass index, systolic and diastolic blood pressure, fasting blood glucose, and total cholesterol in stomach cancer patients.
Conclusion
Moderate drinking can lower cardiovascular risk in cancer survivors, and among the many drinking-related cancers, stomach cancer patients demonstrated significantly reduced cardiovascular risk factors.

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Problem Drinking in Cancer Survivors
Seung-Won Oh
Korean Journal of Family Medicine.2020; 41(4): 205. CrossRef

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Implementation of a Videoconferencing System between Multiple Family Medicine Departments: Kee Hyuck Lee, Ju Young Kim, Kiheon Lee, Belong Cho, Jeong Hee Yang, Eurah Goh, Woo Kyung Bae; Korean J Fam Med 2011;32(5):311-316. Published online July 28, 2011; DOI: https://doi.org/10.4082/kjfm.2011.32.5.311

Abstract
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Attending conferences is important for doctors and residents in family medicine. Nevertheless, departments of family medicine at many hospitals find it difficult to hold regular conferences. Holding joint videoconferences between Family Medicine Departments of several hospitals through a videoconferencing system could solve this problem. Therefore, Family Medicine Departments of Seoul National University Hospital, Seoul National University Bundang Hospital, and Kangwon National University Hospital decided to hold regular joint videoconferences via a videoconferencing system. Eighty-one joint videoconferences were held from April 1 to October 29, 2010. PowerPoint slideshows were transferred to the other two locations in the same resolution as presenter's monitor. Image and voice of the speaker were transferred in real time and in acceptable quality. Joint videoconferences are feasible, satisfactory and useful for medical education, especially when individual family medicine departments are small and lack resources to hold face-to-face conferences. We expect that more family medicine departments will choose to participate in implementing similar joint videoconferencing systems in the future.

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Rebecca Randell, Michael R. Backhouse, E. Andrea Nelson
Informatics for Health and Social Care.2016; 41(4): 362. CrossRef
Experience of a Videoconference System with Medical Information Desktop Sharing for Radiation Therapy and Evaluation of Its Usefulness
Shohei Kawashiro, Yasuhito Hagiwara, Ibuki Ota, Mayumi Ichikawa, Misako Miwa, Yuuki Kuroda, Kenji Nemoto
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology.2014; 03(01): 20. CrossRef
Satisfaction and Difficulties of Korean Family Medicine Resident Training Faculty
Jung-Ha Kim, Ju Young Kim, Kil Young Kwon, Chul-Min Lee, Tae-Hee Jeon, Seung Soo Hyun
Korean Journal of Family Medicine.2013; 34(5): 357. CrossRef
Satisfaction and Effectiveness of a Videoconference System for Family Physicians
Jong-Soo Han, Kee Hyuck Lee, Hyun-Hee Noh, Belong Cho, Jeong-Hee Yang, Dong-Ryul Lee, Soshin Ke, Woo-Kyung Bae
The Journal of the Institute of Webcasting, Internet and Telecommunication.2013; 13(3): 79. CrossRef

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Association of Proteinuria with Metabolic Syndrome in Korean Adults.: Myung Ju Oh, Mi Ji Lee, Kee Hyuck Lee, Min Seon Park, Jeong Ah Ko; Korean J Fam Med 2010;31(6):437-443. Published online June 20, 2010; DOI: https://doi.org/10.4082/kjfm.2010.31.6.437

Abstract
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Background
Proteinuria is a predictor of chronic kidney disease and a common risk factor for cardiovascular disease. Previous studies have reported that a urinary albumin-creatinine ratio and a glomerular filtration rate was related to the metabolic syndrome. However, there have been few studies on association between the metabolic syndrome and proteinuria by the urine dip-stick test. We examined the association between the metabolic syndrome and the proteinuria by the urine dip-stick test. Methods: The subject of this study included 20,075 adults aged more than 18 years old who visited the Health Promotion Center of the Seoul National University Hospital from April 2001 to March 2007. The metabolic syndrome was defined according to the criteria of the American Heart Association and National Heart, Lung and Blood Institute, and proteinuria was defined as a dipstick test above the '1+' level. The crude and multivariated-adjusted odds ratios of proteinuria were calculated by using logistic regression models with each component of the metabolic syndrome.Results: Proteinuria was noticed in 5.7% of the subjects with metabolic syndrome, and 2.7% without metabolic syndrome. The multivariate-adjusted odds ratios of proteinuria in participants with elevated blood pressure level, elevated plasma glucose level and high triglyceride level were 2.23 (95% confidence interval [CI], 1.95 to 2.55), 2.33 (95% CI, 2.06 to 2.62), 1.64 (95% CI, 1.45 to 1.84). The multivariate-adjusted odds ratio of proteinuria in participants with the metabolic syndrome compared with participants without the metabolic syndrome was 2.30 (95% CI, 1.91 to 2.76), respectively.Conclusion: These findings suggest that proteinuria by the urine dip-stick test might be an important predictor in the metabolic syndrome.

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