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"Su-Mi Kim"

Original Article
Relationship of Simple Renal Cyst to Hypertension
Su-Mi Kim, Tae-Heum Chung, Myoung-Soon Oh, Sung-Gul Kwon, Sung-Jin Bae
Korean J Fam Med 2014;35(5):237-242.   Published online September 24, 2014
DOI: https://doi.org/10.4082/kjfm.2014.35.5.237
Background

Simple renal cyst is the most common cystic deformation found in adults. However, there were a few systematic Korean reports for the clinical symptoms and complications of simple renal cysts. The author's purpose was to determine the relationship between simple renal cysts diagnosed by abdominal ultrasonography and hypertension.

Methods

Among 13,482 persons who took a routine physical examination at Ulsan University Hospital in 2002, 5,127 persons who took medical examinations again in 2010 were selected. We excluded persons who had renal cyst, hypertension, diabetes, liver cirrhosis, kidney disease, thyroid disease, and cancer in 2002. Analysis was conducted for 505 subjects with newly diagnosed simple renal cyst and 2,744 subjects without renal cyst in 2010. The simple renal cyst group was compared to a control group without renal cyst.

Results

Among 3,249 subjects, simple renal cyst and hypertension were newly diagnosed in 505 subjects and 503 subjects. The subjects who had simple renal cysts had significantly higher hypertension incidence (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.20 to 1.94). Significant hypertension incidence was observed especially when the subjects had cysts located on both kidneys (OR, 3.48; 95% CI, 2.12 to 5.71), two (OR, 3.08; 95% CI, 1.84 to 5.15) or more cysts (OR, 3.12; 95% CI, 1.38 to 7.04), and larger cysts more than 1 cm in diameter (OR, 1.55; 95% CI, 1.16 to 2.07).

Conclusion

The presence of simple renal cysts was significantly positively related to the incidence of hypertension. Bilateral distribution, two or more number, and larger size than 1 cm diameter were the characteristics of simple renal cyst related to hypertension.

Citations

Citations to this article as recorded by  
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    Frontiers in Molecular Biosciences.2025;[Epub]     CrossRef
  • Relationship Between Simple Renal Cysts and Hypertension: A Systematic Review and Meta-Analysis
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    European Journal of Endocrinology.2023; 189(1): 58.     CrossRef
  • Prevalence, risk factors and clinical characteristics of renal dysfunction in Chinese outpatients with growth simple renal cysts
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    International Urology and Nephrology.2022; 54(7): 1733.     CrossRef
  • The presence of simple renal cysts is associated with an increased risk of albuminuria in young adults
    Hyo Jin Boo, Jung Eun Lee, Son Mi Chung, Hye Ryoun Jang, Wooseong Huh, Dae Joong Kim, Yoon-Goo Kim
    The Korean Journal of Internal Medicine.2022; 37(2): 425.     CrossRef
  • Simple renal cyst as an independent risk factor for hypertension
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    The Journal of Clinical Hypertension.2022; 24(7): 898.     CrossRef
  • Retrospective Evaluation of the Clinical Values of Minimally Invasive Marsupialization of Symptomatic Giant Renal Cysts
    Wael Y. Khoder, Markus Grabbert, August Sigle, Sophie Astheimer, Stefan Vallo, Christian Gratzke
    Journal of Laparoendoscopic & Advanced Surgical Techniques.2021; 31(3): 279.     CrossRef
  • The association between simple renal cyst and aortic diseases: A systematic review and meta‐analysis of observational studies
    Api Chewcharat, Rikuta Hamaya, Charat Thongprayoon, Liam D. Cato, Michael A. Mao, Wisit Cheungpasitporn
    Journal of Evidence-Based Medicine.2020; 13(4): 265.     CrossRef
  • The Novel Use of Flexible Ureteroscopy and Holmium: YAG Laser in the Management of Parapelvic Renal Cysts
    Shaogang WANG
    Urology & Nephrology Open Access Journal.2016;[Epub]     CrossRef
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