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"Yeon Ji Lee"

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"Yeon Ji Lee"

Original Articles
The Association between Low Vitamin D Status and Autoimmune Thyroid Disease in Korean Premenopausal Women: The 6th Korea National Health and Nutrition Examination Survey, 2013–2014
Choon-Young Kim, Yeon Ji Lee, Ji-Ho Choi, Soo Yeon Lee, Hye Young Lee, Da Hye Jeong, Yeon Jun Choi
Korean J Fam Med 2019;40(5):323-328.   Published online September 3, 2019
DOI: https://doi.org/10.4082/kjfm.18.0075
Background
This study aimed to analyze the association of low vitamin D status with thyroid autoimmunity and dysfunction in the Korean population according to sex and menopausal status in women.
Methods
This study was based on the data acquired from the 6th Korea National Health and Nutrition Examination Survey. We enrolled 4,356 subjects who had data of thyroid function, antithyroid peroxidase antibody (TPOAb), and serum 25-hydroxyvitamin D (25[OH]D) levels. We excluded subjects who were pregnant and who had a history of thyroid disease or thyroid cancer, and those with transient thyroid dysfunction who tested negative for TPOAb (TPOAb[-]).
Results
TPOAb positivity (TPOAb[+]) with thyroid dysfunction (subclinical and overt hypothyroidism) was more prevalent in the vitamin D deficient group than in the vitamin D insufficient and sufficient groups including premenopausal (P=0.046) and postmenopausal women (P=0.032), although no significant differences were observed in men. The mean serum 25(OH)D level was significantly lower in the TPOAb(+) with thyroid dysfunction group than in the TPOAb(+) with euthyroidism and TPOAb(-) groups of premenopausal women (P=0.001), although no significant differences were observed in men and postmenopausal women. Multivariate binary logistic regression analysis, adjusted for age, body mass index, and current smoking status, showed that vitamin D insufficiency and deficiency were significantly associated with TPOAb(+) with thyroid dysfunction in premenopausal women (P<0.001), although no significant associations were observed in men and postmenopausal women.
Conclusion
Low vitamin D status was significantly associated with thyroid autoimmunity and dysfunction in the Korean population, especially in premenopausal women.

Citations

Citations to this article as recorded by  
  • Dysregulated vitamin D signaling in Hashimoto’s thyroiditis: an integrated transcriptomic study in a Korean cohort
    Dong-Woo Lim, Ho-Jung Jeong, Jin Seok Lee, Min-Seo Choi, Sungsoon Fang, Jing-Hua Wang, Hojun Kim, Seok-Mo Kim
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Impact of Subclinical Hypothyroidism on Lipid Profile in Jeddah: A Retrospective Cohort Study
    Mahmoud A Alzahrani, Fatemah S Baqar, Basil A Alzahrani, Ziyad A Badri, Rayan Alshamrani, Jamal Aljuhani
    Cureus.2024;[Epub]     CrossRef
  • Vitamin D and the Thyroid: A Critical Review of the Current Evidence
    Mirjana Babić Leko, Iva Jureško, Iva Rozić, Nikolina Pleić, Ivana Gunjača, Tatijana Zemunik
    International Journal of Molecular Sciences.2023; 24(4): 3586.     CrossRef
  • The importance of vitamin d in the thyroid autoimmune diseases
    Milan Jovanović
    Galenika Medical Journal.2023; 2(5): 87.     CrossRef
  • Effectiveness of Maternal Vitamin D Supplementation in Preventing Respiratory Tract Infections in Children
    Soo Young Kim
    Korean Journal of Family Medicine.2022; 43(3): 155.     CrossRef
  • Clinical Study on Vitamin D deficiency in Hypothyroidism
    NEHA PRIYA, RINA KUMARI, SURAJ P WAGH
    Asian Journal of Pharmaceutical and Clinical Research.2022; : 161.     CrossRef
  • The influence of vitamin D and iron on thyroid function and thyroid autoimmunity
    Jasmina Aleksić
    Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma.2022; 27(87): 64.     CrossRef
  • The Interactive Effects of Severe Vitamin D Deficiency and Iodine Nutrition Status on the Risk of Thyroid Disorder in Pregnant Women
    Wei Lu, Zhengyuan Wang, Zhuo Sun, Zehuan Shi, Qi Song, Xueying Cui, Liping Shen, Mengying Qu, Shupeng Mai, Jiajie Zang
    Nutrients.2022; 14(21): 4484.     CrossRef
  • Genetic Susceptibility to Joint Occurrence of Polycystic Ovary Syndrome and Hashimoto’s Thyroiditis: How Far Is Our Understanding?
    Natalia Zeber-Lubecka, Ewa E. Hennig
    Frontiers in Immunology.2021;[Epub]     CrossRef
  • ASSOСIATION BETWEEN VITAMIN D STATUS AND METABOLIC DISORDERS IN PREMENOPAUSAL WOMEN WITH AUTOIMMUNE HYPOTHYROID DISEASE
    Oksana O. Chukur, Nadiya V. Pasyechko, Anzhela O. Bob, Iryna V. Smachylo, Liudmyla V. Radetska
    Wiadomości Lekarskie.2021; 74(7): 1612.     CrossRef
  • Association between vitamin D deficiency and hypothyroidism: results from the National Health and Nutrition Examination Survey (NHANES) 2007–2012
    Sandeep Appunni, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Raees Tonse, Emir Veledar, Peter McGranaghan
    BMC Endocrine Disorders.2021;[Epub]     CrossRef
  • Low Normal TSH Levels and Thyroid Autoimmunity are Associated with an Increased Risk of Osteoporosis in Euthyroid Postmenopausal Women
    Libo Yang, Hongmei Wang, Jinying Guo, Guanlin Zheng, Dailin Wei, Tie Zhang
    Endocrine, Metabolic & Immune Disorders - Drug Targets.2021; 21(5): 859.     CrossRef
  • Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases
    Mattia Bellan, Laura Andreoli, Chiara Mele, Pier Paolo Sainaghi, Cristina Rigamonti, Silvia Piantoni, Carla De Benedittis, Gianluca Aimaretti, Mario Pirisi, Paolo Marzullo
    Nutrients.2020; 12(3): 789.     CrossRef
  • Immunomodulatory Effects of Vitamin D in Thyroid Diseases
    Chiara Mele, Marina Caputo, Alessandro Bisceglia, Maria Teresa Samà, Marco Zavattaro, Gianluca Aimaretti, Loredana Pagano, Flavia Prodam, Paolo Marzullo
    Nutrients.2020; 12(5): 1444.     CrossRef
  • Vitamin D and Autoimmune Thyroid Disease—Cause, Consequence, or a Vicious Cycle?
    Inês Henriques Vieira, Dírcea Rodrigues, Isabel Paiva
    Nutrients.2020; 12(9): 2791.     CrossRef
  • Prospective role of thyroid disorders in monitoring COVID-19 pandemic
    Kanchan Kumari, Gagan B.N. Chainy, Umakanta Subudhi
    Heliyon.2020; 6(12): e05712.     CrossRef
  • 9,608 View
  • 126 Download
  • 15 Web of Science
  • 16 Crossref
Survey of Potentially Inappropriate Prescription Using STOPP/START Criteria in Inha University Hospital
Sang-Jin Lee, Se-Wook Cho, Yeon Ji Lee, Ji-Ho Choi, Hyuk Ga, You-Hoi Kim, So-Yun Woo, Woo-Suc Jung, Dong-Yop Han
Korean J Fam Med 2013;34(5):319-326.   Published online September 26, 2013
DOI: https://doi.org/10.4082/kjfm.2013.34.5.319
Background

Prescribing potentially harmful drugs and omitting essential drugs to older patients is a common problem because they take so many medications. In this study, our goal was to identify potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) using Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) and Screening Tool to Alert doctors to the Right Treatment (START) criteria to improve proper prescription and reduce improper prescription.

Methods

Enrolled in this study were 117 patients older than 65 years old who were hospitalized at Inha University Hospital in Incheon due to pneumonia from January 2012 to March 2012. Patient data, including medical histories, current diagnoses, current medications, and biochemical data were recorded from electronic records. STOPP and START were applied to their clinical datasheets.

Results

STOPP criteria identified 24 patients who had 29 PIMs. Most potential inappropriate prescribing was of cardiovascular medications, followed by drugs whose primary effect is on the urogenital system and gastrointestinal system. START criteria identified 31 patients who had 46 PPOs. The cardiovascular system drugs comprised most of the PPOs. No PPOs were identified under the central nervous system criteria.

Conclusion

Given the current Korean medical system conditions and considering the many clinically important situations when prescribing drugs, STOPP/START criteria are not absolute criteria to prevent improper prescription, but sagacious usage of these standards can help physicians to prescribe properly in clinical practice.

Citations

Citations to this article as recorded by  
  • Enhancing medication appropriateness: Insights from the STOPP (Screening Tool of Older Persons’ Prescriptions) criteria version 3 on prescribing practices among the older adults in Pakistan
    Halima Sadia, Safila Naveed, Hina Rehman, Shazia Jamshed, Huma Dilshad
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • The impact of a multifaceted intervention to reduce potentially inappropriate prescribing among discharged older adults: a before-and-after study
    Muhammad Eid Akkawi, Mohamad Haniki Nik Mohamed, Mohd Aznan Md Aris
    Journal of Pharmaceutical Policy and Practice.2020;[Epub]     CrossRef
  • Evaluation of potentially inappropriate medication utilization in elderly patients with cancer at outpatient oncology unit
    Ceylan Paksoy, Öznur Özkan, Bala BÖ Ustaalioğlu, Mesut Sancar, Refik Demirtunç, Fikret V Izzettin, Betul Okuyan
    Journal of Oncology Pharmacy Practice.2019; 25(6): 1321.     CrossRef
  • Usefulness of STOPP/START criteria to assess appropriateness of medicines prescribed to older adults in a resource-limited setting
    U. G. S. Siripala, S. P. K. Premadasa, N. R. Samaranayake, C. A. Wanigatunge
    International Journal of Clinical Pharmacy.2019; 41(2): 525.     CrossRef
  • Potentially inappropriate prescribing and associated factors in elderly patients at hospital discharge in Brazil: a cross-sectional study
    Ana Luiza Pereira Moreira Mori, Renata Cunha Carvalho, Patricia Melo Aguiar, Maria Goretti Farias de Lima, Magali da Silva Pacheco Nobre Rossi, José Fernando Salvador Carrillo, Egídio Lima Dórea, Sílvia Storpirtis
    International Journal of Clinical Pharmacy.2017; 39(2): 386.     CrossRef
  • Evaluation of polypharmacy and appropriateness of prescription in geriatric patients: A cross-sectional study at a tertiary care hospital
    K. B. Rakesh, Mukta N. Chowta, Ashok K. Shenoy, Rajeshwari Shastry, Sunil B. Pai
    Indian Journal of Pharmacology.2017; 49(1): 16.     CrossRef
  • Examining potentially inappropriate prescribing in residential care using the STOPP/START criteria
    N.J. Ailabouni, P.S. Nishtala, J.M. Tordoff
    European Geriatric Medicine.2016; 7(1): 40.     CrossRef
  • Prevalence of inappropriate medication prescription in the elderly in Nigeria: A comparison of Beers and STOPP criteria
    Joseph O. Fadare, Olufemi O. Desalu, Abimbola M. Obimakinde, Adekunle O. Adeoti, Segun M. Agboola, Felix O. Aina
    International Journal of Risk & Safety in Medicine.2015; 27(4): 177.     CrossRef
  • Difficulty in managing polypharmacy in the elderly: Case report and review of the literature
    Rhita Bennis Nechba, Moncif El M'barki Kadiri, Mounia Bennani-Ziatni, Amine Ali Zeggwagh, Abdelhalim Mesfioui
    Journal of Clinical Gerontology and Geriatrics.2015; 6(1): 30.     CrossRef
  • Consensus Validated List of Potentially Inappropriate Medication for the Elderly and Their Prevalence in South Korea
    Seong-Ok Kim, Sunmee Jang, Chul-Min Kim, Yu-Ri Kim, Hyun Soon Sohn
    International Journal of Gerontology.2015; 9(3): 136.     CrossRef
  • 6,039 View
  • 35 Download
  • 10 Crossref
The Effect of Lifestyle Modification Program for Medical Students' Personal Health Practices.
Si Won Hur, Hyun Su Kim, Ji Young Son, Woo Kyoung Bae, Tae Woo Yoo, Yeon Ji Lee
Korean J Fam Med 2009;30(4):277-284.   Published online April 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.4.277
Background
Lifestyle is an important risk factor for many diseases. We need to educate medical students for advocating health promoting behaviors to their patients. Teaching knowledge, however, was not enough for medical students to change their health-related lifestyle. In this study, we investigated health promoting behaviors of medical students, and the improvement of their health behaviors after competitive lifestyle modifi cation program.Methods: All sophomores of medical college in Seoul National University were included in this study. We performed lifestyle modifi cation program consisting of lecture, group competition, and feedback. We focused on reforming health behaviors like smoking, drinking, exercise, stress management and eating habits. And we also checked common symptoms of functional diseases, medication frequency for relieving these symptoms and general life satisfaction.Results: After 2 months of lifestyle modifi cation program, the obese (P = 0.0455) and the average value of BMI (P < 0.001) were decreased and two of smokers quitted smoking. Numbers of medical students with health related habits such as regular exerciser (P = 0.027), frequent user of symptom-relief medication (P < 0.001), breakfast skipper (P = 0.005) were signifi cantly changed in positive way, and the average value of general life satisfaction score (P = 0.003) was improved.Conclusion: Lifestyle modification program improved medical students' health habits and enhanced general life satis-faction.

Citations

Citations to this article as recorded by  
  • What Kind of Mentoring Do We Need? A Review of Mentoring Program Studies for Medical Students
    Yera Hur, Sun Kim, Keumho Lee
    Korean Journal of Medical Education.2013; 25(1): 5.     CrossRef
  • Happiness of Medical Students and Tasks in Medical Education
    Eun Bi Lim
    Korean Medical Education Review.2011; 13(2): 25.     CrossRef
  • 3,123 View
  • 23 Download
  • 2 Crossref
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