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Original Articles

Effects of the COVID-19 Pandemic on the Medical Use of Elderly Patients with Hypertension: A Nationwide Cohort Study in Korea
Eunbyul Cho, Sujeong Han, Jae-ryun Lee, Hyejin Lee, Bumjo Oh
Korean J Fam Med 2024;45(5):283-289.   Published online March 4, 2024
DOI: https://doi.org/10.4082/kjfm.23.0129
Background
The coronavirus disease 2019 (COVID-19) pandemic has disrupted healthcare services, including chronic disease management, for vulnerable groups, such as older individuals with hypertension. This study aimed to evaluate hypertension management in South Korea’s elderly population during the pandemic using treatment consistency indices such as the continuity of care (COC), modified, modified continuity index (MMCI), and most frequent provider continuity (MFPC).
Methods
This study used the Korea Disease Control and Prevention Agency-COVID-19-National Health Insurance Service cohort (K-COV-N cohort) from the National Health Insurance Service between 2017 and 2021. The research included a total of 4,097,299 hypertensive patients aged 65 years or older. We defined 2018 and 2019 as the baseline period before the COVID-19 pandemic and 2020 and 2021 as the COVID-19 period and calculated the indices of medical continuity (number of visits, COC, MMCI, and MFPC) on a yearly basis.
Results
The number of visits decreased during the COVID-19 period compared to the baseline period (59.64±52.75 vs. 50.49±50.33, P<0.001). However, COC, MMCI, and MFPC were not decreased in the baseline period compared to the COVID-19 period (0.71±0.21 vs. 0.71±0.22, P<0.001; 0.97±0.05 vs. 0.96±0.05, P<0.001; 0.8±0.17 vs. 0.8±0.17, P<0.001, respectively).
Conclusion
COVID-19 had no significant impact on the continuity of care but affected the frequency of outpatient visits for older patients with hypertension. However, this study highlights the importance of addressing healthcare inequalities, especially in older patients with hypertension, during pandemics and advocates for policy changes to ensure continued care for vulnerable populations.

Citations

Citations to this article as recorded by  
  • Reflecting on progress and challenges: the Korean Journal of Family Medicine in 2024
    Seung-Won Oh
    Korean Journal of Family Medicine.2025; 46(2): 55.     CrossRef
  • The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study)
    Aleksandra Ostrowska, Wiktoria Wojciechowska, Marek Rajzer, Thomas Weber, Michael Bursztyn, Alexandre Persu, George Stergiou, Grzegorz Kiełbasa, Marzena Chrostowska, Michaelis Doumas, Gianfranco Parati, Grzegorz Bilo, Guido Grassi, Giuseppe Mancia, Andrze
    European Journal of Internal Medicine.2024;[Epub]     CrossRef
  • 2,683 View
  • 61 Download
  • 1 Web of Science
  • 2 Crossref
Background
Osteoporosis is one of the inevitable diseases affecting an aging society, substantially impacting the quality of life of its population. Protein intake has been shown to be beneficial in reducing the incidence of osteoporosis, and the effects of both animal and vegetable proteins have been studied. However, the relationship between processed meat consumption and osteoporosis has not been studied in Korea. Therefore, we aimed to analyze the correlation between processed meat consumption and incident osteoporosis in adults.
Methods
Our analysis included 1,260 adults aged 50 years and older from the Korean Genome and Epidemiology Study (KoGES), recruited between 2005 and 2020. Participants were categorized into two groups according to their processed meat intake, assessed using a semi-quantitative 103-food item food frequency questionnaire. Diagnosis of osteoporosis was based on questionnaire answers. Multiple Cox hazard regression analyses were conducted to examine the association between processed meat intake and incident osteoporosis.
Results
During an average follow-up period of 8.8 years, 230 participants developed osteoporosis. According to the Cox proportional regression models, the hazard ratio (95% confidence interval) of incident osteoporosis in the high intake group was 0.62 (0.41–0.94), compared to the low intake group after adjusting for confounding variables.
Conclusion
These findings reveal that processed meat protein intake is inversely related to the incidence of osteoporosis in adults aged 50 years and older. This in turn suggests that processed meat intake can be proposed as an additional strategy to prevent osteoporosis.
  • 2,925 View
  • 84 Download

Review Article

Global Mapping of Potentially Inappropriate Prescribing for Older Adults in Community Settings: An Umbrella Review
Nafiseh Ghassab-Abdollahi, Haidar Nadrian, Fatemeh Saadati, Fariba ashazadeh, Elnaz Shaseb, Mina Hashemiparast, Hamid Allahverdipour
Korean J Fam Med 2023;44(4):189-204.   Published online July 18, 2023
DOI: https://doi.org/10.4082/kjfm.23.0032
Potentially inappropriate prescribing (PIP) is a major public health concern with several undesirable health consequences for older adults. In this overview, we aimed to map and gather information from existing literature to provide a better insight into the prevalence of PIP among community dwellers. Electronic databases were searched from their inception to April 2022. The quality of the included systematic reviews (SRs) was assessed using the assessment of multiple systematic reviews checklist. The degree of overlap within the SRs was also evaluated (2% overlap). All SRs on the prevalence of PIP in older individuals in community settings were included, and a narrative approach was used to synthesize data. Nineteen SRs comprising 548 primary studies met the inclusion criteria, and the average quality of the included SRs was moderate. More than half (50.5%) of the primary studies were conducted in Europe, followed by the United States (22.8%), and Asia (18.9%). Thirty different criteria were used in the primary studies to estimate the prevalence of PIP. The most widely used criteria were those presented in Beers (41.8%) and STOPP (Screening Tool of Older Persons’ Prescriptions)/START (Screening Tool to Alert to Right Treatment) (21.8%) criteria. Benzodiazepines, nonsteroidal anti-inflammatory drugs, and antidepressants were the most frequently reported PIPs. A considerable variation in the prevalence of PIP ranging from 0% to 98% was reported by SRs. However, there is a high degree of uncertainty regarding the extent of PIP in community settings. To identify knowledge-to-action gaps, SR authors should consider the differences in prevalence of PIP according to settings, applied tools, data sources, geographical areas, and specific pathologies. There is also a need for primary and SR studies from low- and middle-income countries regarding the prevalence of PIP.
  • 2,403 View
  • 94 Download

Original Articles

Background
Previous studies have shown a close relationship between skipping breakfast and nutritional deficiency. However, the impact of regular eating, including lunch and dinner, has not been studied well. We explored the correlation between regularity and frequency of daily meals and nutritional status.
Methods
We analyzed Korea National Health and Nutrition Examination Surveys between 2016 and 2018. A total of 7,725 adults aged 19–49 years were classified into four groups according to the regularity of meal intake: three-meal regular diet (3MRD), two-meal regular diet, one-meal regular diet, and irregular diet (IRD). Food and nutrient intake was assessed using the 24-hour recall method and estimated by a generalized linear model in complex sample weight variables.
Results
In IRD, there were relatively more females who were not married, lived alone, or reported low levels of education. As subjects ate more meals, more people felt thinner and healthier by themselves. Dietary intake of cereal, vegetables, seaweed, and fiber was directly proportional to the number of regular meals as well as essential components such as water, carbohydrates, protein, fat, and micronutrients. Contrarily, alcohol and beverage consumption was inversely proportional to the number of regular meals. Intake level of legumes, fish, fruits, seasonings, milk, oils, sugars, and cholesterol was consistent regardless of meal frequency.
Conclusion
Our findings suggest that 3MRD showed nutrient adequacy and a healthier profile on body weight, body mass index, waist circumference, blood pressure, serum fasting glucose, total cholesterol, and triglyceride.

Citations

Citations to this article as recorded by  
  • Eating patterns in Korean adults, 1998–2018: increased energy contribution of ultra-processed foods in main meals and snacks
    Sukyoung Jung, Jee Young Kim, Sohyun Park
    European Journal of Nutrition.2024; 63(1): 279.     CrossRef
  • Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019–2021)
    Jin-Ah Seok, Yeon-Kyung Lee
    Nutrition Research and Practice.2024; 18(2): 239.     CrossRef
  • Guidelines for nutrition counseling in primary healthcare clinics
    Gyeongsil Lee, Seung-Won Oh
    Journal of the Korean Medical Association.2024; 67(4): 278.     CrossRef
  • A national cross-sectional study on breakfast skipping-related factors and comparison of nutritional status according to breakfast skipping in older adults based on the 8th Korea National Health and Nutrition Examination Survey (KNHANES, 2020)
    Anna Han, Yean Jung Choi
    The Journal of nutrition, health and aging.2024; 28(9): 100335.     CrossRef
  • The Association between Personality Factors and Metabolic Parameters among Patients with Non-Alcoholic-Fatty Liver Disease and Type 2 Diabetes Mellitus—A Cross-Sectional Study
    Marcin Kosmalski, Rafał Frankowski, Monika Różycka-Kosmalska, Kasper Sipowicz, Tadeusz Pietras, Łukasz Mokros
    Journal of Clinical Medicine.2023; 12(13): 4468.     CrossRef
  • Nutrition fact label (NFL) use is related to meeting the requirements for vitamins and minerals not listed on NFLs: Data from the Korea National Health and Nutritional Examination Survey VIII (2019–2021) for the prepandemic and pandemic periods
    Jung Min Cho, Niravkumar Joshi
    PLOS ONE.2023; 18(12): e0296268.     CrossRef
  • Association between Prediabetes and Meal Patterns Related to Meal Sharing among Korean Young Adults: Eighth Korean National Health and Nutrition Examination Survey, 2019–2020
    Saebom Kim, Sehee Kim, Youngmin Kim, Seonmi Seo, Yu Jin Chung, Sam Cheol Kim
    Korean Journal of Family Practice.2023; 13(3): 179.     CrossRef
  • Meal Frequency, Metabolic Health, and Social Norms
    Young Gyu Cho
    Korean Journal of Family Medicine.2022; 43(5): 275.     CrossRef
  • 4,231 View
  • 107 Download
  • 7 Web of Science
  • 8 Crossref
Risk Factors Related to Serious Adverse Drug Reactions Reported through Electronic Submission during Hospitalization in Elderly Patients
Seon-Hye Won, Sang-Yeon Suh, Eunji Yim, Hong-Yup Ahn
Korean J Fam Med 2022;43(2):125-131.   Published online March 17, 2022
DOI: https://doi.org/10.4082/kjfm.21.0086
Background
Many studies have assessed the risk factors for adverse drug reactions (ADRs) in elderly patients. However, most of these studies have focused on risk factors for ADRs, not serious ADRs (s-ADRs). s-ADRs are commonly found in hospitalized patients. s-ADRs warrant imminent but thorough investigations, given their critical impact on patient health. Therefore, this retrospective study aimed to assess the associated risk factors for s-ADRs in elderly hospitalized patients.
Methods
In-patients aged >65 years having ADRs during hospitalization at a university hospital in Korea between 2010 and 2012 were included. Medical professionals spontaneously reported ADRs using an electronic submission system at the study hospital. Further, all descriptions of ADRs were characterized and categorized through the screening of electronic medical records. We compared the characteristics of patients having s-ADRs with those of patients not having s-ADRs.
Results
There were 353 cases of ADRs, 67 of which were s-ADRs. Patients taking more than eight concomitant drugs showed the highest odds ratio (OR, 11.99; 95% confidence interval [CI], 3.42–42.03). The ratio of aspartate aminotransferase (AST)/alanine aminotransferase (ALT) was also significantly related to s-ADRs (OR, 2.78; 95% CI, 1.33–5.81). The use of antibiotics (OR, 2.39; 95% CI, 1.13–5.02) and antineoplastics (OR, 4.17; 95% CI, 1.09–15.94) were significant risk factors.
Conclusion
Our findings highlight the importance of polypharmacy. Liver function tests (AST/ALT ratio) must be monitored carefully within high-risk groups for ADRs.

Citations

Citations to this article as recorded by  
  • Effect of Epstein–Barr virus on macrophage M2/M1 migration and EphA2 expression in adverse drug reactions
    Ran An, Dong‐Jie Sun, Hao‐Xue Lei, Ang‐Ran He, Ying Tu, Jun‐Ting Tang
    The Journal of Dermatology.2025; 52(1): 87.     CrossRef
  • Risk factors for severe adverse drug reactions in hospitalized patients
    Nemanja Z. Petrović, Ana V. Pejčić, Miloš N. Milosavljević, Slobodan M. Janković
    Open Medicine.2025;[Epub]     CrossRef
  • Drug-Induced Serious Cutaneous Reactions in Hospitalized Patients: A Cross-Sectional Study
    Warisara Jiamsathit, Kansuda Bunarong, Sonthiya Papenkort, Anthony R. Cox, Narumol Jarernsiripornkul
    Journal of Clinical Medicine.2025; 14(3): 857.     CrossRef
  • Epidemiology of reported serious adverse drug reactions due to anti-infectives using nationwide database of Thailand
    Sopit Sittiphan, Apiradee Lim, Haris Khurram, Nurin Dureh, Kwankamon Dittakan, Obed Kwabena Offe Amponsah
    PLOS ONE.2025; 20(2): e0318597.     CrossRef
  • Potential inappropriate medications and drug–drug interactions in adverse drug reactions in the elderly: a retrospective study in a pharmacovigilance database
    Huaqiao Jiang, Yanhua Lin, Weifang Ren, Lina Lu, Xiaofang Tan, Xiaoqun Lv, Ning Zhang
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Drug Related Problems among Older Inpatients at a Tertiary Care Setting
    Porrawee Pramotesiri, Krongtong Putthipokin, Sirasa Ruangritchankul
    Journal of Clinical Medicine.2024; 13(6): 1638.     CrossRef
  • Exploring the community pharmacist’s knowledge, attitude, and practices regarding adverse drug reactions and its reporting in the United Arab Emirates: a survey-based cross-sectional study
    Javedh Shareef, Sathvik Belagodu Sridhar, Mullaicharam Bhupathyraaj, Atiqulla Shariff, Sabin Thomas
    Therapeutic Advances in Drug Safety.2024;[Epub]     CrossRef
  • Severe Adverse Drug Reactions in Korean Elderly Patients
    Jungun Lee
    Korean Journal of Family Medicine.2022; 43(2): 91.     CrossRef
  • 4,754 View
  • 94 Download
  • 7 Web of Science
  • 8 Crossref
Cultural Adaption and Psychometric Analysis of Family APGAR Scale in Iranian Older People
Zeinab Karimi, Zahra Taheri-Kharameh, Fatemeh Sharififard
Korean J Fam Med 2022;43(2):141-146.   Published online March 17, 2022
DOI: https://doi.org/10.4082/kjfm.21.0028
Background
Family function is a necessary factor that influences older people’s health. The Family APGAR has been widely used to study family functions. However, there has been no Persian version of this instrument to assess family function in older people. The aim of this study was to determine the psychometric properties of the Persian version of the Family APGAR Scale to evaluate the perception of family functions.
Methods
The “forward-backward” procedure was applied to translate the scale from English into Persian. The translated version was checked in terms of validity and reliability, with a sample of 281 older people selected from retirement centers. The factor structure of the scale was also tested using a confirmatory factor analysis. To test reliability, internal consistency and test–retest analyses were performed.
Results
The results of the confirmatory factor analysis indicated a good structural model. Criterion-related validity was strongly supported by the pattern of association between the APGAR Scale and the social support survey. Cronbach’s α of the scale was 0.88 and test–retest reliability ranged from 0.96 to 0.98, indicating a good range of reliability.
Conclusion
The findings of this study suggest that the Iranian version of the Family APGAR is a valid and reliable scale to evaluate family functions in health intervention programs.

Citations

Citations to this article as recorded by  
  • Advance care planning readiness among older adults in aged service centers: A cross-sectional study
    Kalok Wong, Haobin Yuan, Stephen Tee, Sinkei Cheong
    International Journal of Nursing Sciences.2025; 12(1): 59.     CrossRef
  • Psychosocial distress in people with overweight and obesity: the role of weight stigma and social support
    Vladimira Timkova, Pavol Mikula, Iveta Nagyova
    Frontiers in Psychology.2025;[Epub]     CrossRef
  • ‘Let the System Do Its Job and Families Handle the Rest’? Protective and Risk Factors Contributing to Pandemic Crisis Parental Burnout
    Roman Ryszard Szałachowski, Wioletta Tuszyńska-Bogucka, Jacek Bogucki
    Journal of Clinical Medicine.2025; 14(2): 617.     CrossRef
  • Homogeneity, dimensionality, convergent and nomological validity of the family APGAR among primary care users in Bucaramanga, Colombia
    Julián Andrés Jaimes-Grimaldos, Carlos Arturo Cassiani-Miranda, Andrés Felipe Tirado-Otálvaro, German Díaz Buitrago, Adalberto Campo-Arias, Sandra Milena Velásquez-Vergara, Andrea Carolina Duran-Bedoya
    Journal of Family Social Work.2025; 28(2): 72.     CrossRef
  • Risk factors and a nomogram for predicting cognitive frailty in Chinese patients with lung cancer receiving drug therapy: A single‐center cross‐sectional study
    Jinping Li, Yan Wang, Minfeng Zhai, Mengyuan Qin, Dandi Zhao, Qian Xiang, Zaoyuan Shao, Panrong Wang, Yan Lin, Yiting Dong, Yan Liu
    Thoracic Cancer.2024; 15(11): 884.     CrossRef
  • Psychometric adequacy of the persian adapted version of the tilburg frailty indicator (P-TFI)
    Maryam Safarnavadeh, Leili Salehi
    BMC Geriatrics.2024;[Epub]     CrossRef
  • Risk Factors Associated with Suicidal Ideation in Students of the Faculty of Medicine and Surgery, URSE
    Iván Antonio García-Montalvo, Diana Matías-Pérez, Silvia Lois López-Castellanos, Enrique López-Ramírez, Moisés Martínez-López
    Psychiatry International.2024; 5(3): 544.     CrossRef
  • Relación de la capacidad funcional y la funcionalidad familiar con la fragilidad en adultos mayores con riesgo cardiovascular en el suroccidente colombiano
    Clara Inés Paz , Betsy Mercedes Ledezma , Diana María Rivera, Mabel Lorena Salazar , María Verónica Torres , Franklin René Patiño, Andry Yasmid Mera-Mamián
    Biomédica.2024; 44(4): 537.     CrossRef
  • Analysis of the Functioning of Families of Children with Autism Spectrum Disorder: A Psychometric Study of the Family APGAR Scale
    Laura Serrano, Esther Vela, Laura Martín
    International Journal of Environmental Research and Public Health.2023; 20(23): 7106.     CrossRef
  • The family dynamics of children on the streets of Ibadan, Southwest Nigeria
    Abimbola M. Obimakinde, Moosa Shabir
    South African Family Practice.2023;[Epub]     CrossRef
  • Nomogram reliability for predicting potential risk in postgraduate medical students with anxiety symptoms
    Zewen Huang, Lejun Zhang, Junyu Wang, Tingting Wang, Lu Xu, Xialing Yang, Heli Lu
    Heliyon.2022; 8(10): e10803.     CrossRef
  • Riesgo familiar total y funcionalidad familiar en hogares de una agrupación familiar de San Juan de Lurigancho, 2021.
    Rocio Miriam Bravo Rojas, Cecilia Olga Martinez Ramos
    Revista Cuidado y Salud Pública.2022; 2(1): 22.     CrossRef
  • 4,609 View
  • 109 Download
  • 10 Web of Science
  • 12 Crossref
Factors that Predict Smoking Cessation among Older Koreans: Based on the Korea National Health and Nutrition Examination Survey 2016–2018
Han Kyul Lim, Yong Soon Park, Jeong Hyeon Kim, Jeong Hyun Kim
Korean J Fam Med 2021;42(5):363-368.   Published online September 20, 2021
DOI: https://doi.org/10.4082/kjfm.20.0203
Background
Tobacco smoking is associated with several diseases and deaths in older Koreans. This study aimed to evaluate the factors associated with smoking cessation in older Koreans.
Methods
We selected 579 subjects who started smoking before the age of 65 years from the Korea National Health and Nutrition Examination Survey 2016–2018. We excluded the subjects who quit smoking before the age of 65 years, and then categorized the rest of subjects into those who stopped smoking after the age of 65 years and those who are constant smokers. Multivariable logistic analysis was performed to evaluate the factors related to smoking cessation among older Koreans.
Results
Among the participants, 66.1% were persistent smokers. After multivariable analysis, the factors significantly associated with smoking cessation were as follows: being in the age group of 75–79 years (adjusted odds ratio [aOR], 4.07; 95% confidence interval [CI], 2.12–7.83), being in the age group of 70–74 years (aOR, 3.10; 95% CI, 1.72–5.61), a family history of ischemic heart disease (aOR, 3.36; 95% CI, 1.09–10.35), and having had no cancer screening (aOR, 0.36; 95% CI, 0.18–0.70).
Conclusion
Further efforts to identify the factors related to smoking cessation will help formulate a smoking cessation policy.

Citations

Citations to this article as recorded by  
  • Current status of health promotion in Korea
    Soo Young Kim
    Journal of the Korean Medical Association.2022; 65(12): 776.     CrossRef
  • 3,850 View
  • 89 Download
  • 1 Web of Science
  • 1 Crossref
Trajectories of Handgrip Strength and Their Associations with Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging
Kyung Hyun Bae, Yong Ho Jo, Dong Ryul Lee, Jungun Lee
Korean J Fam Med 2021;42(1):38-46.   Published online May 27, 2020
DOI: https://doi.org/10.4082/kjfm.19.0140
Background
Handgrip strength (HGS) is a good predictor of adverse health outcomes in later life. This prospective study aimed to investigate whether HGS trajectory patterns were associated with all-cause mortality among older adults in Korea.
Methods
This study used the database of the 2006–2016 Korean Longitudinal Study of Aging. Study participants included 3,069 adults aged ≥65 years without a previous history of cancer. The trajectory model was developed to identify different homogeneous trajectory patterns of HGS according to study period. Cox proportional hazards models were then applied to investigate the association between HGS and all-cause mortality.
Results
The survival probability according to HGS during the follow-up period decreased as base HGS weakened. We identified four distinct trajectory groups of HGS among men and three among women. The risk of mortality increased as the HGS of both males and females decreased. Compared with the highest HGS group, the adjusted hazard ratios for all-cause mortality of the lowest, lower-mid, and upper-mid HGS groups among males were 3.46 (95% confidence interval [CI], 2.17–6.69), 2.26 (95% CI, 1.47–3.48), and 1.58 (95% CI, 1.07–2.32). Those of the low and mid HGS groups among females were 2.69 (95% CI, 1.39–5.21) and 1.97 (95% CI, 1.05–3.69).
Conclusion
The faster HGS declined over time, the greater the all-cause mortality risk increased compared with the slowly decreasing or maintained HGS groups among men and women. HGS measurement among older adults will be helpful in assessing their health statuses and pre-assessing disease-associated morbidity.

Citations

Citations to this article as recorded by  
  • Longitudinal trajectories of handgrip strength and their association with motoric cognitive risk syndrome in older adults
    Hui Chang, Yu Zhao
    Archives of Gerontology and Geriatrics.2024; 120: 105334.     CrossRef
  • Association of absolute and relative hand grip strength with all-cause mortality among middle-aged and old-aged people
    Wonjeong Jeong, Jong Youn Moon, Jae-Hyun Kim
    BMC Geriatrics.2023;[Epub]     CrossRef
  • Analysis of the association between osteoporosis and muscle strength in Korean adults: a national cross-sectional study
    Ji-Young Choi, Young-Mo Yang
    Journal of Health, Population and Nutrition.2023;[Epub]     CrossRef
  • Grip Strength Measurement in the Right Hand Better Predicts Mortality Regardless of Dominant Hand
    Yun-A Shin, Won-Ho Choi, Jae-Hyun Kim
    Exercise Science.2022; 31(1): 110.     CrossRef
  • Longitudinal association of handgrip strength with all-cause and cardiovascular mortality in older adults using a causal framework
    Rubén López-Bueno, Lars Louis Andersen, Joaquín Calatayud, José Casaña, Lee Smith, Louis Jacob, Ai Koyanagi, José Francisco López-Gil, Borja del Pozo Cruz
    Experimental Gerontology.2022; 168: 111951.     CrossRef
  • Importance of Handgrip Strength as a Health Indicator in the Elderly
    Soo Young Kim
    Korean Journal of Family Medicine.2021; 42(1): 1.     CrossRef
  • Grip Strength as a Cardiometabolic Marker
    Jungun Lee
    Korean Journal of Family Medicine.2020; 41(5): 271.     CrossRef
  • 4,880 View
  • 128 Download
  • 5 Web of Science
  • 7 Crossref
Fear of Falling and Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging
Ari Lee, Jungun Lee, Gyumin Lee, Dong Ryul Lee
Korean J Fam Med 2020;41(4):243-249.   Published online May 12, 2020
DOI: https://doi.org/10.4082/kjfm.18.0128
Background
The fear of falling (FOF) has been reported in a high percentage of elderly people. An excessive FOF is a major concern among the elderly because it can lead to permanent disability. However, the impact of FOF on mortality has been insufficiently studied. The aim of this study was to investigate the impact of FOF on mortality among the elderly in Korea.
Methods
This was a prospective study carried out using the database of the Korean Longitudinal Study of Aging, a nationwide study of community-dwelling adults in Korea. Study participants included 3,421 adults, aged 65 years or older, without either severe cognitive impairment (Korean version of Mini-Mental Status Examination ≥10), or previous history of cancer. We used Cox proportional hazards models to investigate the association between FOF and all-cause mortality.
Results
This study included 1,474 men and 1,947 women. Cox regression showed that participants with FOF had an increased risk of mortality (mild: hazard ratio [HR], 1.25; 95% confidence interval [CI], 1.01−1.54; moderate: HR, 1.59; 95% CI, 1.23−2.05) after adjusting for confounding variables. In a subgroup analysis, FOF was still a significant risk factor of mortality for patients with no previous history of falling after adjusting for other risk factors, as in the full model, except for history of falling (HR, 1.65; 95% CI, 1.27−2.13).
Conclusion
We found that FOF was a significant risk factor for mortality in the elderly in Korea. Further studies on the effects and mechanism of FOF on mortality are needed.

Citations

Citations to this article as recorded by  
  • Association between fear of falling and mortality in middle-aged and older adults: A systematic review and meta-analysis
    Wenlian Ma, Xiaoli Liang, Hongyan Wang, Zhifei Wen, Linfeng Liu, Liangliang Fan, Xiangeng Zhang
    Geriatric Nursing.2024; 59: 113.     CrossRef
  • Factors Associated with Fear of Falling by Fall Experience in the Community-dwelling Elderly
    Yeong Mi Seo, Eun Sook Lee
    Research in Community and Public Health Nursing.2023; 34: 12.     CrossRef
  • Bidirectional relationship between fear of falling and frailty among community-dwelling older adults: A longitudinal study
    Cen Mo, Wenting Peng, Yuqian Luo, Siyuan Tang, Minhui Liu
    Geriatric Nursing.2023; 51: 286.     CrossRef
  • Fear of falling and all-cause mortality among young-old community-dwelling adults: a 6-year prospective study
    Giulia Belloni, Christophe Büla, Brigitte Santos-Eggimann, Yves Henchoz, Sarah Fustinoni, Laurence Seematter-Bagnoud
    European Journal of Ageing.2022; 19(2): 293.     CrossRef
  • A comparison of the prevalence of Fear of Falling between older patients with Lewy body dementia, Alzheimer's disease, and without dementia
    Pinar Soysal, Semen Gokce Tan, Lee Smith
    Experimental Gerontology.2021; 146: 111248.     CrossRef
  • 4,380 View
  • 101 Download
  • 4 Web of Science
  • 5 Crossref
The Impact of Depression on Cardiovascular Disease: A Nationwide Population-Based Cohort Study in Korean Elderly
Dong Han Park, Jung Jin Cho, Jong Lull Yoon, Mee Young Kim, Young Soo Ju
Korean J Fam Med 2020;41(5):299-305.   Published online May 8, 2020
DOI: https://doi.org/10.4082/kjfm.18.0134
Background
Depression is suggested to be associated with cardiovascular disease, including ischemic heart disease and cerebrovascular disease. This study investigated the impact of depression on cardiovascular disease in the elderly population in Korea.
Methods
This retrospective cohort study was performed using the Senior Cohort database released by the Korean National Health Insurance Services from January 1, 2008 to December 31, 2012, or January 1, 2009 to December 31, 2013. The study group constituted participants newly diagnosed with depression, but not cardiovascular disease. The control group constituted participants with no past history of depression or cardiovascular disease, and were not diagnosed with depression during the follow-up period. During the 5-year follow-up period, development of ischemic heart disease or cerebrovascular disease was assessed. Depression and cardiovascular disease were identified using the International Classification of Diseases, 10th revision, Clinical Modification codes. The data was analyzed using Cox proportional hazards model.
Results
The hazard ratio (HR) between depression and ischemic heart disease was 1.38 (95% confidence interval [CI], 1.23 to 1.55) and the HR between depression and cerebrovascular disease was 1.46 (95% CI, 1.32 to 1.62), after adjusting all confounding variables.
Conclusion
Independent of other cardiovascular risk factors, depression increased the risk of ischemic heart disease by 38% and cerebrovascular disease by 46% among older adults in Korea. Since depression may increase the risk of cardiovascular disease, future research should focus on the diagnosis and prevention of cardiovascular disease in people with depression.

Citations

Citations to this article as recorded by  
  • The effect of scutellaria baicalensis and its active ingredients on major depressive disorder: a systematic review and meta-analysis of literature in pre-clinical research
    Ying Ma, Xun Zhou, Feng Zhang, Cuiyun Huang, Hong Yang, Wansheng Chen, Xia Tao
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Factors Associated with the Intention to Quit Smoking in Elderly Korean Men: The Korea National Health and Nutrition Examination Survey 2010-2015
Inho Lee, Yong Soon Park, Jeong Hyeon Kim, Seung Hyeok Han
Korean J Fam Med 2020;41(4):237-242.   Published online April 24, 2020
DOI: https://doi.org/10.4082/kjfm.18.0124
Background
Tobacco smoking is the most preventable cause of diseases and death in older adults. This study aimed to evaluate the factors associated with the intention to quit smoking in elderly Korean men.
Methods
We investigated 813 male smokers aged 65 years or more from the 5th and 6th Korea National Health and Nutrition Examination Survey 2010–2015. Multiple logistic regression analysis was performed to identify factors related with smoking cessation intention.
Results
Of the respondents, 26.3% had the intention to quit smoking. After adjustment for confounding factors, the intention to quit smoking was significantly associated with a history of ischemic heart disease (adjusted odds ratio, 1.88; 95% confidence interval, 1.02–3.48).
Conclusion
Identifying the factors related to the intention to quit smoking among older adults can help in developing effective smoking cessation strategies for this section of the population.

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  • Factors Associated with Quit Intentions among Adult Smokers in South Korea: Findings from the 2020 ITC Korea Survey
    Minjung Han, Donghee Seo, Yeol Kim, Hong Gwan Seo, Sung-il Cho, Sungkyu Lee, Sujin Lim, Susan C. Kaai, Anne C. K. Quah, Mi Yan, Steve S. Xu, Geoffrey T. Fong
    International Journal of Environmental Research and Public Health.2022; 19(17): 10839.     CrossRef
  • Factors that Predict Smoking Cessation among Older Koreans: Based on the Korea National Health and Nutrition Examination Survey 2016–2018
    Han Kyul Lim, Yong Soon Park, Jeong Hyeon Kim, Jeong Hyun Kim
    Korean Journal of Family Medicine.2021; 42(5): 363.     CrossRef
  • 4,088 View
  • 96 Download
  • 2 Web of Science
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Association between Falls and Nutritional Status of Community-Dwelling Elderly People in Korea
Ah-Ra Jo, Mi-Jeong Park, Byung-Gue Lee, Young-Gyun Seo, Hong-Ji Song, Yu-Jin Paek, Kyung-Hee Park, Hye-Mi Noh
Korean J Fam Med 2020;41(2):111-118.   Published online March 19, 2020
DOI: https://doi.org/10.4082/kjfm.18.0112
Background
Malnutrition is a well-known risk factor of falls, although studies examining the association between nutritional status and falls are rare. We aimed to investigate the association between nutritional status and falls according to gender among Korean older adults.
Methods
The study included 10,675 participants (4,605 men and 6,070 women) aged 65 years and older and used data from the 2011 Survey of Living Conditions and Welfare Needs of Korean Older Persons. Nutritional status of the participants was assessed using the Nutritional Screening Initiative checklist, and the participants were categorized into the following groups: “good,” “moderate nutritional risk,” and “high nutritional risk.” Odds ratios (OR) of fall risk in the above groups based on gender were evaluated using multivariate logistic regression analyses.
Results
Fallers in both genders showed significant association with older age, lower household income, inadequate exercise, and poor nutritional status compared with non-fallers. Considering the good nutritional status group as the reference group, the high nutritional risk group showed a higher risk of falls in men (OR, 1.59; 95% confidence interval [CI], 1.26–1.99); both moderate and high nutritional risk groups showed a higher risk of falls after adjusting for confounding factors in women (OR, 1.39; 95% CI, 1.19–1.62 and OR, 1.90; 95% CI, 1.61–2.24, respectively).
Conclusion
The risk of falls was associated with poor nutritional status, and statistical significance of the association between nutritional status and falls was stronger in women than in men.

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  • Mapping sex and gender differences in falls among older adults: A scoping review
    Crista Sebastiani, Jamie Yee Xin Wong, Amandeep Litt, Julia Loewen, Karly Reece, Nicole Conlin, Tessa Dunand, Manuel Montero Odasso, Cassandra D'Amore, Stephanie Saunders, Marla Beauchamp
    Journal of the American Geriatrics Society.2024; 72(3): 903.     CrossRef
  • Temporal trends and the association between self-rated oral health and falls in community-dwelling older adults in South Korea: a secondary analysis of survey data
    Hyun-Ju Seo, Soon-Ki Ahn, Min-Jung Choi
    BMJ Open.2024; 14(4): e081549.     CrossRef
  • Age and Gender Differences in Fall-Related Factors Affecting Community-Dwelling Older Adults
    Minhee SUH, Da Hye KIM, Insook CHO, Ok Kyung HAM
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    Thitima Phodhichai, Warapone Satheannoppakao, Mathuros Tipayamongkholgul, Carol Hutchinson, Siriphan Sasat
    Public Health Nutrition.2022; 25(3): 565.     CrossRef
  • Current status of nutrient intake in Korea: focused on macronutrients
    Seung-Won Oh
    Journal of the Korean Medical Association.2022; 65(12): 801.     CrossRef
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  • 112 Download
  • 5 Web of Science
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Association between Serum-Ferritin Levels and Sleep Duration, Stress, Depression, and Suicidal Ideation in Older Koreans: Fifth Korea National Health and Nutrition Examination Survey 2010–2012
Kyung Mi Kim, Hye Rim Hwang, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Sung In Chung
Korean J Fam Med 2019;40(6):380-387.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.18.0097
Background
Serum-ferritin levels may be associated with psychiatric symptoms among the elderly; however, this association has not been extensively studied. The aim of this study was to evaluate the association between serumferritin levels and mental health issues in older Koreans.
Methods
This cross-sectional study included large-scale national data from the Korea National Health and Nutrition Examination Survey 2010–2012. In total, 1,802 older Koreans (≥65 years old) were included. The assessed psychiatric symptoms included short sleep duration, stress, depressed mood, and suicidal ideation. Any association between serum-ferritin levels and mental health issues according to sex was examined using logistic regression analysis.
Results
The prevalence of short sleep duration, stress, depressed mood, and suicidal ideation was 50.9%, 21.7%, 18.2%, and 22.5%, respectively. In men, suicidal ideation decreased with increased serum-ferritin levels after multivariate adjustment for sociodemographic and lifestyle factors and comorbidities. The odds ratios (OR) and 95% confidence interval (CI) of suicidal ideation by quartiles of serum-ferritin level were 1 (reference), 1.132 (95% CI, 0.569–2.252), 0.453 (95% CI, 0.217–0.945), and 0.608 (95% CI, 0.295–1.253), respectively, (P for trend=0.039). In women, no trend was observed. However, compared to the lowest quartile, short sleep duration (<7 h) and stress perception were significantly decreased in the third quartile, with odds ratios of 0.601 (95% CI, 0.461–0.888), and 0.606 (95% CI, 0.386–0.952), respectively.
Conclusion
Moderate serum-ferritin levels were associated with decreased risk for suicide ideation in men, and were associated with decreased short sleep duration and stress perception in women.

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    Jie Li, Lan Wang, Ziyi Wang, Fengxue Zhao, Yadi Sun, Ying Lu, Lei Yang
    BMC Geriatrics.2024;[Epub]     CrossRef
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    Acır Ibrahim, Atay Zeynep Vildan Okudan , Atay Mehmet , Yayla Vildan
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    Irma Clemente, Gaia Sinatti, Antonio Cirella, Silvano Junior Santini, Clara Balsano
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    Journal of Clinical Medicine.2022; 11(21): 6554.     CrossRef
  • Suicidal Ideation in Major Depressed Individuals: Role of Type D Personality
    Mokhtar Abdelhakim Laoufi, Benjamin Wacquier, Tristan Lartigolle, Gwenolé Loas, Matthieu Hein
    Journal of Clinical Medicine.2022; 11(22): 6611.     CrossRef
  • 10,443 View
  • 129 Download
  • 4 Web of Science
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Unintentional Injuries among the Elderly in Rural Areas and Their Related Behaviors
Forouzan Rezapur-Shahkolai, Nasrin Sayfian, Babak Moeini, Ghodratollah Roshanaei
Korean J Fam Med 2019;40(2):80-86.   Published online February 28, 2019
DOI: https://doi.org/10.4082/kjfm.17.0124
Background
Although the role of unintentional injuries as a cause of death in adults is known, there is limited knowledge about such adults’ behaviors. This study aims to investigate the frequency of and factors affecting unintentional injuries among the elderly living in rural areas and their related behaviors.
Methods
A cross-sectional study was carried out in the rural areas of Hamadan County, Iran, in 2016. The sample consists of randomly selected 445 adults aged 60–75 years. Data collection was conducted through face-to-face interviews, using questionnaires.
Results
One hundred and forty-three participants (34.7%) experienced 166 injury occurrences. The injuries occurred more in females than in males. There were more mild and severe injuries (48.2% and 31.3%, respectively) than moderate ones (20.5%). The most frequent mechanism of injuries was accidental falls (64.5%). There was a significant relationship between using aid devices and injuries (P=0.001). Among the most applied injury preventive measures as reported by the elderly, crossing streets safely and the use of proper lighting at night had the highest percentages (81.5% and 69.7%, respectively). However, the use of protective handles and plastic flooring in bathrooms in order to prevent slipping had the lowest percentages (less than 1.0%).
Conclusion
The injuries among the elderly in this study were important health concerns. Injury-related factors should be considered in the development of injury prevention programs.
  • 5,088 View
  • 97 Download
Mild Anemia and Risk for All-Cause, Cardiovascular and Cancer Deaths in Apparently Healthy Elderly Koreans
Sil Vi Han, Minseon Park, Young-Min Kwon, Hyung-Jin Yoon, Yoosoo Chang, Ho Kim, Youn-Hee Lim, Su Gyeong Kim, Ahryoung Ko
Korean J Fam Med 2019;40(3):151-158.   Published online January 17, 2019
DOI: https://doi.org/10.4082/kjfm.17.0089
Background
Being common, mild anemia is sometimes considered a mere consequence of aging; however, aging alone is unlikely to lead to anemia. Therefore, this study aimed to investigate the association between mild anemia and total mortality and cause-specific mortality in apparently healthy elderly subjects.
Methods
A retrospective cohort study was conducted on 10,114 apparently healthy elderly individuals who underwent cancer screening and routine medical check-ups at one Health Promotion Center between May 1995 and December 2007. We defined mild anemia as a hemoglobin concentration between 10.0 g/dL and 11.9 g/dL in women and between 10.0 g/dL and 12.9 g/dL in men. We assessed the relationship between the overall, cardiovascular (CV), and cancer mortality and mild anemia using Cox proportional hazard models.
Results
Mild anemia was present in 143 men (3.1%) and 246 women (6.1%). During an average follow-up of 7.6 years, 495 deaths occurred, including 121 CV and 225 cancer deaths. After adjustments, mild anemia was associated with a 128% increase in the risk of all-cause mortality hazard ratio (HR, 2.28; 95% confidence interval [CI], 1.54– 3.37) in men and cancer-related mortality (HR, 2.25; 95% CI, 1.22–4.13), particularly lung cancer (HR, 2.70; 95% CI, 1.03–7.08) in men, but not in women. In the subgroup analyses based on smoking status, obesity, and age, the associations were more prominent in never or former smoker groups and the older group.
Conclusion
The present study shows that overall and cancer-related mortality was associated with mild anemia in elderly men. Future prospective studies are needed to consolidate our findings.

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    Gerontology.2024; 70(10): 1023.     CrossRef
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    Advances in Pharmacological and Pharmaceutical Sciences.2022; 2022: 1.     CrossRef
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    Iranian Biomedical Journal.2022; 26(5): 389.     CrossRef
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    BMJ Open.2022; 12(12): e056674.     CrossRef
  • ASSOCIATION OF ANEMIA WITH EXTRASYSTOLIA IN PATIENTS WITH SENIOR ASTHENIA
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  • A patient with cardiovascular disease and anaemia: fatal combination or consistent pattern?
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  • High anemia prevalence in Korean older adults, an advent healthcare problem: 2007–2016 KNHANES
    Hee Won Chueh, Hye Lim Jung, Ye Jee Shim, Hyoung Soo Choi, Jin Yeong Han
    BMC Geriatrics.2020;[Epub]     CrossRef
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  • 8 Web of Science
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The Association between Family Mealtime and Depression in Elderly Koreans
Yunhwa Kang, Soyeon Kang, Kyung Jung Kim, Hyunyoung Ko, Jinyoung Shin, Yun-Mi Song
Korean J Fam Med 2018;39(6):340-346.   Published online October 31, 2018
DOI: https://doi.org/10.4082/kjfm.17.0060
Background
Several studies have revealed the frequency of family mealtimes to be inversely associated with depressive symptoms in adolescents. However, there have been few studies in older populations. This cross-sectional study investigated the association between family mealtime frequency and depressive symptoms in elderly Koreans.
Methods
This study analyzed 4,959 elderly men and women (aged 65 years or older) who participated in the Korea National Health and Nutrition Examination Survey. Self-administered questionnaires were used to assess depressive status, family mealtime frequency, and covariates. Multiple logistic regression analysis was performed to evaluate the association using the eating alone group as a reference.
Results
After adjusting for all covariates, participants who had family meals 3 times a day had fewer depressive symptoms than the eating alone group; adjusted odds ratios (ORs) (95% confidence intervals [CIs]) were 0.72 (0.58– 0.89) for point depressiveness/anxiety and 0.73 (0.56–0.94) for depressiveness lasting for at least 2 weeks. In suicidal ideation, the OR (95% CI) of eating with family twice a day was significant after full adjusting for covariates at 0.67 (0.50–0.88).
Conclusion
Family mealtimes were closely associated with depressive symptoms in elderly Koreans, which suggests that maintaining intrafamilial bonding is important for mental health in an older population.

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    Experimental Gerontology.2023; 172: 112072.     CrossRef
  • Longitudinal association between eating alone and deterioration in frailty status: The Korean Frailty and Aging Cohort Study
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    Experimental Gerontology.2023; 172: 112078.     CrossRef
  • Modeling suicidal ideation in Korean older adults based on their social relationships and mental health: a meta-analytic path analysis
    Sin-Hyang Kim, Sihyun Park
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    International Journal of Environmental Research and Public Health.2022; 19(8): 4692.     CrossRef
  • Association between Dining with Companions and Depression among Korean Adults
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  • Eating alone and depressive symptoms among the Japanese working population: The Furukawa nutrition and health study
    Takako Miki, Masafumi Eguchi, Takeshi Kochi, Shamima Akter, Yosuke Inoue, Miwa Yamaguchi, Akiko Nanri, Rie Akamatsu, Isamu Kabe, Tetsuya Mizoue
    Journal of Psychiatric Research.2021; 143: 492.     CrossRef
  • Gender and age group differences in nutrition intake and dietary quality of Korean adults eating alone: based on Korean National Health and Nutrition Examination Survey Data, 2013–2016
    Yoonjin Ahn, Youngmi Lee, Haeryun Park, Kyunghee Song
    Nutrition Research and Practice.2021; 15(1): 66.     CrossRef
  • Association between commensality with depression and suicidal ideation of Korean adults: the sixth and seventh Korean National Health and Nutrition Examination Survey, 2013, 2015, 2017
    Yoon Hee Son, Sarah Soyeon Oh, Sung-In Jang, Eun-Cheol Park, So-Hee Park
    Nutrition Journal.2020;[Epub]     CrossRef
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  • 13 Web of Science
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Factors Associated with Dry Eye Symptoms in Elderly Koreans: the Fifth Korea National Health and Nutrition Examination Survey 2010–2012
Kyong In Kim, Yong Soon Park, Ryoung Hee Kim, Jeong Hyeon Kim
Korean J Fam Med 2019;40(1):22-30.   Published online October 29, 2018
DOI: https://doi.org/10.4082/kjfm.17.0058
Background
Dry eye disease is an aging-related ophthalmic disease that not only affects the daily activities but also causes deterioration in the quality of life. This study aimed to evaluate the factors associated with dry eye symptoms in elderly Koreans.
Methods
We investigated 4,185 subjects (men=1,787 and women=2,398) aged ≥65 years from the fifth Korea National Health and Nutrition Examination Survey 2010−2012. Data were analyzed using multiple logistic regressions to identify the relationships between dry eye symptoms and other factors.
Results
The prevalence of dry eye symptoms was 17.9%. After adjustment for confounding factors, dry eye symptoms were significantly associated with female sex (adjusted odds ratio [aOR], 1.806; 95% confidence interval [CI], 1.410−2.313), a history of cataract (aOR, 1.683; 95% CI, 1.255−2.255), suicidal ideation (aOR, 1.414; 95% CI, 1.070−1.870), hypercholesterolemia (aOR, 1.289; 95% CI, 1.025−1.621), age ≥80 years (aOR, 0.538; 95% CI, 0.337−0.859), and sleep duration ≥9 h/d (aOR, 0.524; 95% CI, 0.330−0.834).
Conclusion
Among elderly Koreans, female sex, a history of cataract, suicidal ideation, and hypercholesterolemia may be the risk factors for dry eye symptoms, whereas sleep duration ≥9 h/d can be a protective factor against dry eye symptoms.

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    Hao Zeng, Xue Yang, Kai Liao, Xin Zuo, Lihong Liang, Dalian He, Rong Ju, Bowen Wang, Jin Yuan
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    Kuiliang Yang, Shangcao Wu, Lan Ke, Han Zhang, Shanshan Wan, Mingzhi Lu, Jiewen Mao, Yuelan Gao, Yanning Yang, Yiqiao Xing, Wanju Yang
    Medicine.2024; 103(52): e41019.     CrossRef
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    Qinxiang Zheng, Saiqing Li, Feng Wen, Zhong Lin, Kemi Feng, Yexiang Sun, Jie Bao, Hongfei Weng, Peng Shen, Hongbo Lin, Wei Chen
    Frontiers in Medicine.2022;[Epub]     CrossRef
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    Muhammad Ali Tariq, Hamza Amin, Bilal Ahmed, Uzair Ali, Ashar Mohiuddin
    Indian Journal of Ophthalmology.2022; 70(6): 1892.     CrossRef
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    Kyung Wook Kim, Jin Sun Hwang, Jiwon Chang, Young Joo Shin
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    Hyungoo Kang, Yuyeon Jung
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  • 105 Download
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Case Report

Acquired Hemophilia in a Patient Presenting with Swollen Left Limb
George Wong Pah Kiam
Korean J Fam Med 2019;40(2):129-132.   Published online July 13, 2018
DOI: https://doi.org/10.4082/kjfm.17.0126
Acquired hemophilia is a rare, potentially life-threatening disease that usually remains under-recognized especially in a primary setting; thus, diagnosing this disease is very challenging. Given its prevalence in elderly patients, awareness and diagnosis of this condition in the aging population (particularly those with unexplained bleeding or prolonged activated partial thromboplastin time) should be improved and better managed by the clinicians. Early diagnosis and prompt treatment are usually effective in preventing the adverse outcomes of this disease. In this report, we discuss a case of an elderly patient with acquired hemophilia who initially presented with swelling of his lower left limb. The diagnosis of acquired hemophilia was made a month after the appearance of symptoms. Early diagnosis with proper treatment could have been provided to this patient, if the initial assessment had been thoroughly conducted.

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    Ali Taher, Layal Al Mahmasani, Abdallah Aadra, Patricia Yazbeck, Georges Abi Saad, Fadi Nasr, Rita Habib, Amal Chalfoun, Fadi Haddad
    Hematology.2021; 26(1): 83.     CrossRef
  • 6,158 View
  • 71 Download
  • 1 Web of Science
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Original Articles

Association of High-Risk Drinking with Metabolic Syndrome and Its Components in Elderly Korean Men: The Korean National Health and Nutrition Examination Survey 2010–2012
Ji-Hyun Kim, Jeong-Im Ha, Jae-Min Park, Ji Sun Lee, Ah-Leum Ahn, Eun-Jung Oh, Jae-Kyung Choi, Hyuk-Jung Kweon, Dong-Yung Cho
Korean J Fam Med 2018;39(4):233-238.   Published online July 6, 2018
DOI: https://doi.org/10.4082/kjfm.17.0024
Background
Previous studies have examined the association between alcohol consumption and metabolic syndrome (MetS) in adults, but studies in the elderly are lacking. We examined the relationship between high-risk alcohol consumption and MetS in elderly Korean men using the Alcohol Use Disorders Identification Test (AUDIT) questionnaire from the 2010–2012 Korean National Health and Nutrition Examination Survey.
Methods
Among 25,534 subjects, 2,807 were men >60 years of age; after exclusions, we included 2,088 men in the final analysis. We categorized the study participants into three groups according to AUDIT score: low risk (0–7), intermediate risk (8–14), and high risk (≥15 points).
Results
Among the study population, 17.0% of the men were high-risk drinkers, who had the highest mean waist circumference, systolic and diastolic blood pressure (BP), fasting plasma glucose (FPG), and triglyceride (TG) levels. The overall prevalence of MetS was 41.9% in the elderly men, and it was significantly higher in the group with high (48.3%) versus low (31.9%) AUDIT scores. The prevalence of MetS components (elevated BP, high FPG, high TG, and low high-density lipoprotein cholesterol) was associated with a high AUDIT score. The odds ratios (95% confidence interval) of the high-risk group for MetS, elevated BP, and high TG were 1.40 (1.03–1.89), 1.82 (1.28– 2.60), and 1.77 (1.30–2.41) after adjustment for confounding variables.
Conclusion
AUDIT score was correlated with most MetS components in elderly Korean men.

Citations

Citations to this article as recorded by  
  • Sex-Specific Energy Intakes and Physical Activity Levels According to the Presence of Metabolic Syndrome in Korean Elderly People: Korean National Health and Nutrition Examination Survey 2016–2018
    Won-Sang Jung, Hun-Young Park, Sung-Woo Kim, Kiwon Lim
    International Journal of Environmental Research and Public Health.2020; 17(15): 5416.     CrossRef
  • Cardiovascular effects of alcohol: A double-edged sword / how to remain at the nadir point of the J-Curve?
    Theodora A. Manolis, Antonis A. Manolis, Antonis S. Manolis
    Alcohol.2019; 76: 117.     CrossRef
  • High-Risk Drinking in the Elderly
    Seung-Won Oh
    Korean Journal of Family Medicine.2018; 39(4): 209.     CrossRef
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  • 130 Download
  • 3 Web of Science
  • 3 Crossref
Relationship between Marital Status and Metabolic Syndrome in Korean Middle-Aged Women: The Sixth Korea National Health and Nutrition Examination Survey (2013–2014)
Young-Ah Jung, Li-Ly Kang, Ha-Nui Kim, Hoon-Ki Park, Hwan-Sik Hwang, Kye-Yeung Park
Korean J Fam Med 2018;39(5):307-312.   Published online July 6, 2018
DOI: https://doi.org/10.4082/kjfm.17.0020
Background
This study aimed to investigate the relationship between marital status and the incidence of metabolic syndrome in Korean middle-aged women.
Methods
Based on data from the sixth Korea National Health and Nutrition Examination Survey (2013–2014), 3,225 women aged 40–69 years were subjected to the analysis. Marital status was categorized as married, unmarried, separated, widowed, or divorced. The odds ratios (ORs) for metabolic syndrome were calculated based on marital status. After adjustment for age, income level, education level, alcohol intake, smoking status, leisure physical activity, menopause status, daily calories, and fat intake, changes in the OR for metabolic syndrome based on marital status were examined by multivariate logistic regression analysis.
Results
The OR for metabolic syndrome in the widowed group to the married group was 4.818 (95% confidence interval [CI], 3.861–6.002; P<0.001) and that after adjustment of age, economic level, education level, alcohol intake, smoking status, physical activity, menopause status, total daily calories, and fat intake was 2.141 (CI, 1.432–3.199; P<0.001), both of which were statistically significant. The OR for metabolic syndrome in the unmarried group to the married group was 0.246 (CI, 0.141–0.431; P<0.001) after adjustment of all components. On the contrary, the ORs of the separated group and the divorced group to the married group were not significant.
Conclusion
In comparison with the married middle-aged group, the widowed middle-aged group tended to have a higher risk of metabolic syndrome, which is speculated to be related to socioeconomic factors and health behavior.

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    Cardiovascular Diabetology.2024;[Epub]     CrossRef
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    SN Comprehensive Clinical Medicine.2023;[Epub]     CrossRef
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    Aileen R. de Juras, Wan-Chen Hsu, Susan C. Hu
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    Dilnessa Fentie, Tariku Derese, Bekele Yazie, Yibeltal Getachew
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The Association between Social Support and Happiness among Elderly in Iran
Babak Moeini, Majid Barati, Maryam Farhadian, Milad Heydari Ara
Korean J Fam Med 2018;39(4):260-265.   Published online July 4, 2018
DOI: https://doi.org/10.4082/kjfm.17.0121
Background
Elderly people’s life is affected by multiple factors including social support, which is of the utmost importance. This study aimed to explore the association between social support and happiness as well as the impact of types of social support on happiness among elders.
Methods
This descriptive and analytical study was carried out on 411 elderly men and women referred to the retirement, cultural, and rehabilitation centers in Hamadan, west of Iran. Participants were selected by a multi-stage random sampling method. The research instrument included a questionnaire consisting of three parts: demographic information, the Oxford Argyle Happiness Inventory, and a Questionnaire derived from Social Support Theory. The questionnaire was completed through a self-report study. The collected data were analyzed using Pearson correlation coefficients, multiple linear regression, independent t-tests, and one-way analysis of variance in IBM SPSS Software ver. 22.0.
Results
The mean for happiness was reported as 41.17±15.2. The values given for social support were 29.40±11.95 and for its dimensions were 7.53±3.89 and 13.70±4.90 for informational support and emotional support, respectively. Moreover, the mean value for appraisal support was 3.48±2.37 and was 4.70±2.56 for instrumental support. Multiple linear regression analysis revealed that social support and demographic variables could account for approximately 25% (R2 =0.25) of changes in the variable of happiness.
Conclusion
High social support could increase happiness among elders. The quality and quantity of social support can be taken into account as proper determinants and predictors of happiness among elders.

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Brief Communication

Background

Protein intake in South Korea is generally considered to be adequate; however, there is concern that it may be inadequate among the elderly. This study evaluated the adequacy of protein intake, the source of protein, and the distribution of protein intake in daily meals in the Korean elderly population.

Methods

Data were obtained from 1,484 men and 2,028 women aged 60 years or older who had participated in the nutrition survey of the 2013–2014 Korea National Health and Nutrition Examination Survey. One-day (24-hour) recall data were used to estimate the daily protein intake.

Results

The mean protein intake was 65.3±1.0 g/d (13.1%±0.1% of energy) and 49.7±0.7 g/d (12.6%±0.1% of energy) for men and women, respectively. The protein intake was less than the estimated average requirement in 30.8%±1.4% of men and 42.6%±1.3% of women, and 47.9%±1.6% and 60.1%±1.4%, respectively, consumed less than the recommended daily allowance. The protein intake was relatively evenly distributed among meals; however, the absolute amount of protein consumption per meal was very low. Only one-third of the protein intake came from animal sources.

Conclusion

The quantity and quality of protein intake were inadequate in the elderly Korean population.

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    Hye-Mi Noh, Yi Hwa Choi, Soo Kyung Lee, Hong Ji Song, Yong Soon Park, Namhyun Kim, Jeonghoon Cho
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    Hyunji Ham, Kyungho Ha
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    Eunseo Heu, Yunjung Lee, Donghyun Kim, Yong-Chan Ha, Yongsoon Park
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    Seon-Joo Park, Junghyun Park, Chang Won Won, Hae-Jeung Lee
    Nutrients.2022; 14(7): 1375.     CrossRef
  • The Association Between Total Protein Intake and All-Cause Mortality in Middle Aged and Older Korean Adults With Chronic Kidney Disease
    Yu-Jin Kwon, Hye Sun Lee, Go Eun Park, Hyung-Mi Kim, Jung Joo Lee, Woo Jeong Kim, Ji-Won Lee
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • Frequency of steamed food consumption and risk of metabolic syndrome in Korean females: data from Korean Genome and Epidemiology Study
    Young-Ran Heo, Jeong-Hwa Choi
    Journal of Nutrition and Health.2022; 55(2): 309.     CrossRef
  • Low-protein diet is inversely related to the incidence of chronic kidney disease in middle-aged and older adults: results from a community-based prospective cohort study
    Yu-Jin Kwon, Kyongmin Park, Jun-Hyuk Lee
    European Journal of Nutrition.2022; 61(7): 3795.     CrossRef
  • Associations between the quality of life in sarcopenia measured with the SarQoL® and nutritional status
    Yongtaek Kim, Ki Soo Park, Jun Il Yoo
    Health and Quality of Life Outcomes.2021;[Epub]     CrossRef
  • Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity
    Minjeong Chae, Hyoung Su Park, Kyong Park
    Nutrition Research and Practice.2021; 15(2): 203.     CrossRef
  • Adequate protein intake in older adults in the context of frailty: cross-sectional results of the Nutrition and Health Survey in Taiwan 2014–2017
    Szu-Yun Wu, Nai-Hua Yeh, Hsing-Yi Chang, Chi-Fen Wang, Shu-Yi Hung, Shin-Jiuan Wu, Wen-Harn Pan
    The American Journal of Clinical Nutrition.2021; 114(2): 649.     CrossRef
  • Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults
    Seonghee Park, Minjeong Chae, Hyoungsu Park, Kyong Park
    Nutrients.2021; 13(5): 1522.     CrossRef
  • Dairy protein intake is inversely related to development of non-alcoholic fatty liver disease
    Jun-Hyuk Lee, Hye Sun Lee, Sang Bong Ahn, Yu-Jin Kwon
    Clinical Nutrition.2021; 40(10): 5252.     CrossRef
  • Dietary Protein Intake Dynamics in Elderly Chinese from 1991 to 2018
    Yifei Ouyang, Tingyi Tan, Xiaoyun Song, Feifei Huang, Bing Zhang, Gangqiang Ding, Huijun Wang
    Nutrients.2021; 13(11): 3806.     CrossRef
  • Macronutrient Intake in Adults Diagnosed with Metabolic Syndrome: Using the Health Examinee (HEXA) Cohort
    Hyerim Park, Anthony Kityo, Yeonjin Kim, Sang-Ah Lee
    Nutrients.2021; 13(12): 4457.     CrossRef
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    Yongjun Jang, Sun Im, Yeonjae Han, Hyunjung Koo, Donggyun Sohn, Geun-Young Park
    Journal of Clinical Neuroscience.2020; 71: 113.     CrossRef
  • Association of milk consumption frequency on muscle mass and strength: an analysis of three representative Korean population studies
    Jun-Hyuk Lee, Hye Sun Lee, Hyungmi Kim, Yu-Jin Kwon, Ji-Won Lee
    European Journal of Nutrition.2020; 59(7): 3257.     CrossRef
  • Estimation of Dietary Amino Acid Intake and Independent Correlates of Skeletal Muscle Mass Index among Korean Adults
    Minjeong Chae, Hyoungsu Park, Kyong Park
    Nutrients.2020; 12(4): 1043.     CrossRef
  • Socio-Economic Factors are Associated with Risk of Inadequate Protein Intake among Korean Elderly: Based on the Seventh Korean National Health and Nutrition Examination Survey (KNHANES Ⅶ), 2016-2018
    Won Jang, Ho Kyung Ryu
    The Korean Journal of Community Living Science.2020; 31(2): 215.     CrossRef
  • Protein intake and osteosarcopenic adiposity in Korean adults aged 50 years and older
    M.-K. Choi, Y.-J. Bae
    Osteoporosis International.2020; 31(12): 2363.     CrossRef
  • Effect of Dairy Protein Intake on Muscle Mass among Korean Adults: A Prospective Cohort Study
    Eunjin So, Hyojee Joung
    Nutrients.2020; 12(9): 2537.     CrossRef
  • Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study


    Hyejin Chun, Gi Dae Kim, Miae Doo
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 3601.     CrossRef
  • Animal Protein Intake Is Positively Associated with Metabolic Syndrome Risk Factors in Middle-Aged Korean Men
    Sangwon Chung, Min-Yu Chung, Hyo-Kyoung Choi, Jae Ho Park, Jin-Taek Hwang, Hyojee Joung
    Nutrients.2020; 12(11): 3415.     CrossRef
  • Different Associations of Socioeconomic Status on Protein Intake in the Korean Elderly Population: A Cross-Sectional Analysis of the Korea National Health and Nutrition Examination Survey
    Du Ho Kwon, Hyun Ah Park, Young Gyu Cho, Kyoung Woo Kim, Na Hee Kim
    Nutrients.2019; 12(1): 10.     CrossRef
  • Animal and Plant Protein Intake and Body Mass Index and Waist Circumference in a Korean Elderly Population
    Ki-Byeong Park, Hyun Ah Park, Jae-Heon Kang, Kyoungwoo Kim, Young Gyu Cho, Jinyoung Jang
    Nutrients.2018; 10(5): 577.     CrossRef
  • Protein Intake Recommendation for Korean Older Adults to Prevent Sarcopenia: Expert Consensus by the Korean Geriatric Society and the Korean Nutrition Society
    Hee-Won Jung, Sun-Wook Kim, Il-Young Kim, Jae-Young Lim, Hyoung-Su Park, Wook Song, Hyung Joon Yoo, Hak- Chul Jang, Kirang Kim, Yongsoon Park, Yoon Jung Park, Soo Jin Yang, Hae-Jeung Lee, Chang Won Won
    Annals of Geriatric Medicine and Research.2018; 22(4): 167.     CrossRef
  • 6,715 View
  • 187 Download
  • 26 Web of Science
  • 33 Crossref

Original Article

Association between Female Urinary Incontinence and Geriatric Health Problems: Results from Korean Longitudinal Study of Ageing (2006)
Kyungjin Sohn, Chang Ki Lee, Jinyoung Shin, Jungkwon Lee
Korean J Fam Med 2018;39(1):10-14.   Published online January 23, 2018
DOI: https://doi.org/10.4082/kjfm.2018.39.1.10
Background

Urinary incontinence (UI) is highly prevalent in the aging population. UI is one of the most common geriatric syndromes and affects overall health, quality of life, and economical burden in patients. The aims of this study were to investigate the characteristics of patients with UI and to assess its association with other geriatric health problems.

Methods

We used data from the Korean Longitudinal Study of Ageing obtained in 2006. Among the 10,254 individuals aged 45 years and older, we analyzed data from 2,418 women aged 65 years and older. Data were obtained using questionnaires for UI, comorbidities, and lifestyle factors.

Results

Among the 2,418 women aged 65 years and older, 506 (20.9%) had UI. Cerebrovascular disease (odds ratio [OR], 2.02; 95% confidence interval [CI], 1.26 to 3.23), arthritis (OR, 1.44; 95% CI, 1.18 to 1.77), and fear of falling (OR, 1.62; 95% CI, 1.18 to 2.22) were significantly associated with UI, while chronic lung disease, psychiatric disease, difficulty in daily living due to visual and hearing problems, and experiencing a fall in the last 2 years were not associated with UI.

Conclusion

Cerebrovascular disease, arthritis, and especially fear of falls were significantly associated with UI in elderly Korean women.

Citations

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  • Health risks associated with urinary incontinence among older Korean Americans living in subsidized senior housing
    Yuri Jang, Juyoung Park, Jung In Park, Hi-Woo Lee, Soondool Chung, Sunmin Lee
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    Eda Yakit Ak, Mehmet Ali Şen, Abdulkadir Aydin
    International Journal of Urological Nursing.2025;[Epub]     CrossRef
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    Qinggang Liu, Linna Wang, Limin Liao, Huiling Cong, Yi Gao
    Neurourology and Urodynamics.2024; 43(4): 951.     CrossRef
  • Older women with urinary incontinence have higher prevalence of dynapenia: A cross-sectional study
    Luis Fernando Ferreira, Jéssica Roda Cardoso, Priscilla Dalenogare, Cislaine Machado de Souza, Gabriela Tomedi Leites, Luis Henrique Telles da Rosa, Patrícia Viana da Rosa
    MOJ Gerontology & Geriatrics.2024; 9(1): 17.     CrossRef
  • The relationship between serum alpha-klotho levels and urinary incontinence in middle-aged and older females: insights from NHANES
    Xiaoyan Tang, Yanhua Song, Hao Liang, Wenjin He, Zili Chen, Li Yang, Cheng Yang, Rui Du
    Scientific Reports.2024;[Epub]     CrossRef
  • Prevalence of urinary incontinence and its associated predictor and Self-care behavior among the elderly females in Chaiyaphum Province, Thailand: Cross-sectional study
    Patchareepon Chompoowisate, Sumattana Glangkarn, Chaloemporn Namyota
    Journal of Education and Health Promotion.2024;[Epub]     CrossRef
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    Danielle Scharp, Sarah E. Harkins, Maxim Topaz
    Geriatric Nursing.2023; 53: 280.     CrossRef
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    Eda Yakit Ak, Umran Oskay
    International Journal of Urological Nursing.2022; 16(2): 157.     CrossRef
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    Marciane Kessler, Pâmela Moraes Volz, Janaína Duarte Bender, Bruno Pereira Nunes, Karla Pereira Machado, Mirelle de Oliveira Saes, Mariangela Uhlmann Soares, Luiz Augusto Facchini, Elaine Thumé
    Ciência & Saúde Coletiva.2022; 27(6): 2259.     CrossRef
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    Sedighe Batmani, Rostam Jalali, Masoud Mohammadi, Shadi Bokaee
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    Shinje Moon, Hye Soo Chung, Yoon Jung Kim, Sung Jin Kim, Ohseong Kwon, Young Goo Lee, Jae Myung Yu, Sung Tae Cho, Peter F.W.M. Rosier
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    Jungun Lee
    Korean Journal of Family Medicine.2020; 41(1): 1.     CrossRef
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    Isabel C. R. V. Santos, Jair L. dos Santos Júnior, Tayne F. L. da Silva, Natália M. S. de Albuquerque, Jabiael C. da Silva Filho, Marilia P. Valença
    International Journal of Urological Nursing.2019; 13(3): 99.     CrossRef
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Case Report

A Brief Psychotic Episode with Depressive Symptoms in Silent Right Frontal Lobe Infarct
Salziyan Badrin, Noraini Mohamad, Nor Akma Yunus, Maryam Mohd Zulkifli
Korean J Fam Med 2017;38(6):380-382.   Published online November 14, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.6.380

Psychiatric symptoms may be related to a silent cerebral infarct, a phenomenon that has been described previously in literature. Acute psychosis or other neuropsychiatric symptoms including depression may present in stroke patients and patients with lesions either within the prefrontal or occipital cortices, or in subcortical areas such as the basal ganglia, thalamus, mid-brain, and brainstem. Psychosis in clinical stroke or in silent cerebral infarction is uncommon and not well documented in the literature. Neurological deficits are the most common presentation in stroke, and nearly a third of patients that suffer a stroke may experience psychological disorders such as depression and anxiety, related to physical disability. The present case report describes an elderly female patient who presented with hallucinations and depressive symptoms, and was discovered to have a recent right frontal brain infarction, without other significant neurological deficits.

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  • Influence of Evidence-Based Nursing on Psychological Status, Neurological Function, and Life Quality of Patients with Acute Poststroke Depression
    Yan Song, Fei Wang, Yakun Yang, Xing Liu, Chenghong Zhu, Zhongjie Shi
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    Tuğba İlkem KURTOĞLU ÖZÇAĞLAYAN, Demet ÖZKARAMANLI GÜR, Ömer ÖZÇAĞLAYAN, Birol TOPCU, Aysun ÜNAL
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    Firas Ido, Reina Badran, Brandon Dmytruk, Zain Kulairi
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Original Articles
Association of Coffee Consumption with Sarcopenia in Korean Elderly Men: Analysis Using the Korea National Health and Nutrition Examination Survey, 2008–2011
Hyewon Chung, Ji Hyun Moon, Ju Il Kim, Mi Hee Kong, Jung Sik Huh, Hyeon Ju Kim
Korean J Fam Med 2017;38(3):141-147.   Published online May 23, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.3.141
Background

Sarcopenia is an age-related loss of muscle mass and strength. Coffee has antioxidant and anti-inflammatory properties that have been shown to be inversely related to the mechanism of sarcopenia. While there have been some studies on the effect of coffee on sarcopenia in animals, studies on the topic in humans are rare. Therefore, we investigated this relationship in elderly Korean men.

Methods

The cross-sectional data were derived from the 2008–2011 Korea National Health and Nutrition Examination Survey. After applying the exclusion criteria, the study sample consisted of 1,781 men who were at least 60 years of age. Study participants were identified as having sarcopenia if their appendicular skeletal muscle mass divided by height squared was less than two standard deviations below the gender-specific mean of this value for young adults. Daily coffee consumption amounts were categorized as <1 cup, 1 cup, 2 cups, and ≥3 cups.

Results

Compared to the group of individuals who drank less than one cup of coffee a day, people who consumed at least 3 cups (adjusted odds ratio, 0.43; 95% confidence interval, 0.20 to 0.94) showed significantly decreased sarcopenia; however, the decrease was not significant when the daily coffee consumption was 1 or 2 cups. In multivariate logistic regression models, significant associations were observed between sarcopenia and coffee consumption (P for trend=0.039).

Conclusion

The results of this study suggest that consuming at least 3 cups of coffee per day was associated with a lower prevalence of sarcopenia in elderly Korean elderly men.

Citations

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  • Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia
    Mathieu Membrez, Eugenia Migliavacca, Stefan Christen, Keisuke Yaku, Jennifer Trieu, Alaina K. Lee, Francesco Morandini, Maria Pilar Giner, Jade Stiner, Mikhail V. Makarov, Emma S. Garratt, Maria F. Vasiloglou, Lucie Chanvillard, Emilie Dalbram, Amy M. Eh
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    D. P. Kurmaev, S. V. Bulgakova, E. V. Treneva
    Experimental and Clinical Gastroenterology.2024; (2): 141.     CrossRef
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    Huangyi Yin, Wei Zhu, Liuqing Guo, Weishan Li, Min Liang
    Frontiers in Nutrition.2024;[Epub]     CrossRef
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    Cátia R. Lopes, Rodrigo A. Cunha
    Ageing Research Reviews.2024; 102: 102581.     CrossRef
  • Coffee consumption and skeletal muscle mass: WASEDA’S Health Study
    Ryoko Kawakami, Kumpei Tanisawa, Tomoko Ito, Chiyoko Usui, Kaori Ishii, Isao Muraoka, Katsuhiko Suzuki, Shizuo Sakamoto, Mitsuru Higuchi, Koichiro Oka
    British Journal of Nutrition.2023; 130(1): 127.     CrossRef
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    Niloufar Rasaei, Rasool Ghaffarian-Ensaf, Fatemeh Gholami, Farideh Shiraseb, Alireza Khadem, Seyedeh Fatemeh Fatemi, Khadijeh Mirzaei
    BMC Endocrine Disorders.2023;[Epub]     CrossRef
  • Association of habitual coffee consumption with obesity, sarcopenia, bone mineral density and cardiovascular risk factors: A two-year follow-up study in kidney transplant recipients
    Mariana Silva da Costa, Karine Scanci da Silva Pontes, Marcella Rodrigues Guedes, Maria Inês Barreto Silva, Márcia Regina Simas Torres Klein
    Clinical Nutrition.2023; 42(10): 1889.     CrossRef
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    Christian Göbl, Andrea Tura
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    Simon Mazeaud, Fabio Castellana, Hélio Coelho-Junior, Francesco Panza, Mariangela Rondanelli, Federico Fassio, Giovanni De Pergola, Roberta Zupo, Rodolfo Sardone
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    Anna Izzo, Elena Massimino, Gabriele Riccardi, Giuseppe Della Pepa
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    L. de Freitas Lima, F. de Faria Ghetti, H. H. M. Hermsdorff, D. G. de Oliveira, G. Teixeira, L. E. V. V. de Castro Ferreira, A. P. B. Moreira
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    Jungun Lee
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Potentially Inappropriate Medications by Beers Criteria in Older Outpatients: Prevalence and Risk Factors
Yeon-Jung Lim, Ha-Yeon Kim, Jaekyung Choi, Ji Sun Lee, Ah-Leum Ahn, Eun-Jung Oh, Dong-Yung Cho, Hyuk-Jung Kweon
Korean J Fam Med 2016;37(6):329-333.   Published online November 18, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.6.329
Background

Prescription of inappropriate medicine to elderly patients is a major public health care concern. The Beers criteria have been commonly employed as a screening tool to identify the use of potentially inappropriate medications (PIMs). The present study investigated the prevalence of PIM use according to the Beers criteria as well as factors related to PIM use.

Methods

Data obtained from a retrospective survey included 25,810 outpatients aged ≥65 years from a university medical center in Seoul, Korea. PIMs were defined using the Beers criteria. Factors associated with PIM use were evaluated using multiple regression analysis.

Results

Of all participants, 7,132 (27.6%) were prescribed at least one PIM. The most commonly prescribed PIMs were alprazolam (11.2%), clonazepam (10.8%), zolpidem (8.7%), quetiapine (8.4%), and hydroxyzine (5.4%). In multivariate logistic regression analysis, having five or more prescription medicines (odds ratio [OR], 11.32; 95% confidence interval [CI], 9.38 to 13.66) and five or more prescribing doctors (OR, 4.40; 95% CI, 3.59 to 5.39) were strongly associated with PIM. In a likelihood ratio test for trend, an increasing number of medications and prescribing doctors were both significantly associated with PIM.

Conclusion

At a university medical center, the number of medications and the number of prescribing doctors was associated with PIM in older outpatients.

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    Soojung Hong, Ju Hyun Lee, Eun Kyeong Chun, Kwang-Il Kim, Jin Won Kim, Se Hyun Kim, Yun-Gyoo Lee, In Gyu Hwang, Jin Young Kim, Su-Jin Koh, Yoon Ho Ko, Seong Hoon Shin, In Sook Woo, Tae-Yong Kim, Ji Yeon Baek, Hyun Jung Kim, Hyo Jung Kim, Myung Ah Lee, Jun
    The Oncologist.2020; 25(3): e502.     CrossRef
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    Samah Alshehri, Mohannad Alshibani, Ghaydaa Magboul, Albandari Albandar, Roaa Nasser, Roaya M. Yaqoub, Jumana Alzuhayri, Ahmed Aljabri
    Geriatrics.2020; 5(4): 97.     CrossRef
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    Betty Poot, Katherine Nelson, Rebecca Zonneveld, Mark Weatherall
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  • Association of Geriatric Syndromes with Urinary Incontinence according to Sex and Urinary-Incontinence–Related Quality of Life in Older Inpatients: A Cross-Sectional Study of an Acute Care Hospital
    Kyoung Jin Kim, Jinyoung Shin, Jaekyung Choi, Jae-Min Park, Hyoung Keun Park, Jongmin Lee, Seol-Heui Han
    Korean Journal of Family Medicine.2019; 40(4): 235.     CrossRef
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    Sule Ajibola Saka, Frasia Oosthuizen, Manimbulu Nlooto
    International Journal of Clinical Pharmacy.2019; 41(1): 207.     CrossRef
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    BongKyoo Choi, Hi Gin Sung, Jin Hyun Nam, Ju‐Young Shin
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    Tariq M. Alhawassi, Wafa Alatawi, Monira Alwhaibi
    BMC Geriatrics.2019;[Epub]     CrossRef
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    Benjamin S. Walker, Bryan R. Collier, Katie L. Bower, Daniel I. Lollar, Emily R. Faulks, Miguel Matos, Michael S. Nussbaum, Mark E. Hamill
    The American Surgeon™.2019; 85(8): 877.     CrossRef
  • Prevalence and predictors of potentially inappropriate prescribing of central nervous system and psychotropic drugs among elderly patients: A national population study in Korea
    Hyeonseok Cho, Junjeong Choi, Young-Sang Kim, Sang Joon Son, Kang Soo Lee, Hee-Jin Hwang, Hye-Young Kang
    Archives of Gerontology and Geriatrics.2018; 74: 1.     CrossRef
  • Use of the Frailty Index and FRAIL-NH Scale for the Assessment of the Frailty Status of Elderly Individuals Admitted in a Long-term Care Hospital in Korea
    Hyuk Ga, Chang Won Won, Hee-Won Jung
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  • Inappropriate Prescribing in Older Hospitalized Adults: A Comparison of Medical Specialties
    Ana Carmen dos Santos Ribeiro Simoes Juliano, Alessandra Lamas Granero Lucchetti, Jéssica Teixeira Santos da Silva, Letícia Gomes Santos, Jéssica Borges Taranto Nunes, Guilherme Cortes Fernandes, Giancarlo Lucchetti
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  • Potentially inappropriate medications in community-dwelling older adults undertaken as a comprehensive geriatric risk assessment
    Sharmin S. Bala, Sujita W. Narayan, Prasad S. Nishtala
    European Journal of Clinical Pharmacology.2018; 74(5): 645.     CrossRef
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Body Mass Index and Mortality according to Gender in a Community-Dwelling Elderly Population: The 3-Year Follow-up Findings from the Living Profiles of Older People Surveys in Korea
Seon Yeong Yu, Byung Sung Kim, Chang Won Won, Hyunrim Choi, Sunyoung Kim, Hyung Woo Kim, Min Joung Kim
Korean J Fam Med 2016;37(6):317-322.   Published online November 18, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.6.317
Background

Body mass index is widely regarded as an important predictor of mortality. The purpose of this study was to investigate the relationship between body mass index and mortality and to compare community-dwelling elderly people in South Korea according to sex.

Methods

Data were collected from the 2008 and 2011 Living Profiles of Older People Surveys, which comprised 10,613 community-living South Korean men and women aged 65 years or older. The participants were stratified into five groups according to body mass index as defined by the World Health Organization guidelines. The sociodemographic characteristics of participants and mortality rates were compared across the body mass index groups.

Results

The highest survival rates were observed in men with a body mass index of 25.0–29.9 kg/m2. A similar trend was observed in women, but it was not statistically significant. After adjusting for covariates, this association was also found in men across all BMI index groups, but not in women.

Conclusion

This study supports previous findings that overweight or mild obesity is associated with the lowest mortality and suggests that the current categories of obesity require revision. Furthermore, the absence of statistically significant findings in the female cohort suggests that body mass index is not a suitable predictor of mortality in women and that an alternative is required.

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  • Prognostic effect of body mass index to mortality in Korean older persons
    Haksun Kim, Jong L Yoon, Aeyoung Lee, Yujin Jung, Mee Y Kim, Jung J Cho, Young S Ju
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Association between Living Arrangements and Influenza Vaccination Rates among Elderly South Korean People: The Fifth Korea National Health and Nutrition Examination Survey (KNHANES V-2)
Hye Min Cho, Joo-Yeon Kim, Seo Eun Hwang, Jae Chul Kim, Moo-Young Kim, Soo Hyoung Lee
Korean J Fam Med 2015;36(4):186-190.   Published online July 17, 2015
DOI: https://doi.org/10.4082/kjfm.2015.36.4.186
Background

This study aimed to investigate the association between living arrangements and influenza vaccination among elderly South Korean subjects.

Methods

We used data from the fifth Korean National Health and Nutrition Examination Survey. Participants older than 65 years were included and categorized into 4 groups according to the type of living arrangement as follows: (1) living alone group; (2) living with a spouse group; (3) living with offspring (without spouse) group; and (4) living with other family members group. A total of 1,435 participants were included in this cross-sectional analysis.

Results

A lower vaccination rate was observed in the living with offspring (without spouse) group, whereas the living with a spouse group had higher rates of both seasonal and H1N1 influenza vaccination. After adjusting for age, sex, region, education level, income level, and number of comorbidities, the living with offspring (without spouse) group had a higher H1N1 vaccination non-receipt rate than the living alone group (odds ratio, 2.03; 95% confidence interval, 1.08-3.82).

Conclusion

Influenza vaccination rates differed according to the type of living arrangement. Particularly, those living with offspring (without spouse) had the lowest H1N1 influenza vaccination rate compared to those with other living arrangements, and this difference was significant. Interventions to improve influenza vaccination coverage should target not only elderly persons who live alone, but also those living with offspring.

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  • Understanding Factors Contributing to Vaccine Hesitancy in a Large Metropolitan Area
    Paolo Montuori, Immanuela Gentile, Claudio Fiorilla, Michele Sorrentino, Benedetto Schiavone, Valerio Fattore, Fabio Coscetta, Alessandra Riccardi, Antonio Villani, Ugo Trama, Francesca Pennino, Maria Triassi, Antonio Nardone
    Vaccines.2023; 11(10): 1558.     CrossRef
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    Min Kim, Bumhee Yang, Seonhye Gu, Eung-Gook Kim, So Rae Kim, Kyeong Seok Oh, Woong-Su Yoon, Dae-Hwan Bae, Ju Hee Lee, Sang Min Kim, Woong Gil Choi, Jang-Whan Bae, Kyung-Kuk Hwang, Dong-Woon Kim, Myeong-Chan Cho, Hyun Lee, Dae-In Lee
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
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    Jung Keun Park, Soo Lee, Ji Eun Lee, Kyung-Do Han, Ji Hyun Kim, Jin Hee Yoon, Suk Won Park, Yang-Hyun Kim, Kyung-Hwan Cho
    Korean Journal of Family Medicine.2018; 39(2): 90.     CrossRef
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    Kyeong Hyang Byeon, Jaiyong Kim, Boyoung Choi, Bo Youl Choi
    Epidemiology and Health.2018; 40: e2018034.     CrossRef
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    Gyeong-Ran Byeon, Yang-Im Hur, Jae-Heon Kang, Hyun-Ah Park, Kyoung-Woo Kim, Young-Gyu Cho, Koh-Eun Shin, Bong-Hee Kang
    Korean Journal of Health Promotion.2016; 16(1): 20.     CrossRef
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Association between Muscle Loss and Urinary Incontinence in Elderly Korean Women
Hyun-Jung Park, Se-Ryung Choo, Sang-Hyuk Kim, Hyun-Ki Lee, Ki Young Son
Korean J Fam Med 2015;36(1):22-34.   Published online January 31, 2015
DOI: https://doi.org/10.4082/kjfm.2015.36.1.22
Background

Incontinence and muscle loss are important senior health issues. Nevertheless, there are no available domestic or international studies on the association between urinary incontinence and muscle loss. The aim of this study was to investigate the association between muscle loss and urinary incontinence in elderly Korean woman.

Methods

Korean women (1,313) ≥65 years of age whose complete body composition data were collected using dual X-ray absorptiometry were analyzed from the Fourth Korean National Health and Nutritional Examination Surveys. Class I and II losses of the appendicular, truncal, and total muscle mass were defined using adjustments for weight and height. Each participant's incontinence status was collected using constructed questionnaires. Multiple logistic regression was performed to examine the association between muscle loss and incontinence.

Results

On the basis of physician-diagnosed incontinence, weight- and height-adjusted muscle loss showed no association with urinary incontinence (weight-adjusted muscle loss: class I adjusted odds ratio [aOR], 0.77; 95% confidence interval [CI], 0.34 to 1.73; class II aOR, 1.37; 95% CI, 0.59 to 3.18; height-adjusted muscle loss: class I aOR, 0.51; 95% CI, 0.18 to 1.51; class II aOR, 1.86; 95% CI, 0.22 to 15.79). Similar results were observed for truncal muscle and total muscle mass as well as self-reported urinary incontinence.

Conclusion

Our study found no association between urinary incontinence and appendicular, truncal, and total muscle loss in elderly Korean women.

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Survey of Potentially Inappropriate Prescription Using STOPP/START Criteria in Inha University Hospital
Sang-Jin Lee, Se-Wook Cho, Yeon Ji Lee, Ji-Ho Choi, Hyuk Ga, You-Hoi Kim, So-Yun Woo, Woo-Suc Jung, Dong-Yop Han
Korean J Fam Med 2013;34(5):319-326.   Published online September 26, 2013
DOI: https://doi.org/10.4082/kjfm.2013.34.5.319
Background

Prescribing potentially harmful drugs and omitting essential drugs to older patients is a common problem because they take so many medications. In this study, our goal was to identify potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) using Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) and Screening Tool to Alert doctors to the Right Treatment (START) criteria to improve proper prescription and reduce improper prescription.

Methods

Enrolled in this study were 117 patients older than 65 years old who were hospitalized at Inha University Hospital in Incheon due to pneumonia from January 2012 to March 2012. Patient data, including medical histories, current diagnoses, current medications, and biochemical data were recorded from electronic records. STOPP and START were applied to their clinical datasheets.

Results

STOPP criteria identified 24 patients who had 29 PIMs. Most potential inappropriate prescribing was of cardiovascular medications, followed by drugs whose primary effect is on the urogenital system and gastrointestinal system. START criteria identified 31 patients who had 46 PPOs. The cardiovascular system drugs comprised most of the PPOs. No PPOs were identified under the central nervous system criteria.

Conclusion

Given the current Korean medical system conditions and considering the many clinically important situations when prescribing drugs, STOPP/START criteria are not absolute criteria to prevent improper prescription, but sagacious usage of these standards can help physicians to prescribe properly in clinical practice.

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  • The impact of a multifaceted intervention to reduce potentially inappropriate prescribing among discharged older adults: a before-and-after study
    Muhammad Eid Akkawi, Mohamad Haniki Nik Mohamed, Mohd Aznan Md Aris
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    Ceylan Paksoy, Öznur Özkan, Bala BÖ Ustaalioğlu, Mesut Sancar, Refik Demirtunç, Fikret V Izzettin, Betul Okuyan
    Journal of Oncology Pharmacy Practice.2019; 25(6): 1321.     CrossRef
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    International Journal of Clinical Pharmacy.2019; 41(2): 525.     CrossRef
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    International Journal of Clinical Pharmacy.2017; 39(2): 386.     CrossRef
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    N.J. Ailabouni, P.S. Nishtala, J.M. Tordoff
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    Joseph O. Fadare, Olufemi O. Desalu, Abimbola M. Obimakinde, Adekunle O. Adeoti, Segun M. Agboola, Felix O. Aina
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    Seong-Ok Kim, Sunmee Jang, Chul-Min Kim, Yu-Ri Kim, Hyun Soon Sohn
    International Journal of Gerontology.2015; 9(3): 136.     CrossRef
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