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"Caffeine"

Original Articles
Relationship between Dry Eye Syndrome and Frequency of Coffee Consumption in Korean Adults: Korea National Health and Nutrition Examination Survey V, 2010–2012
Kwon-Jin Jeong, Jong-Gi Choi, Eun-Joo Park, Hyo-Eun Kim, Sun-Mi Yoo, Seung-Guk Park
Korean J Fam Med 2018;39(5):290-294.   Published online July 27, 2018
DOI: https://doi.org/10.4082/kjfm.17.0047
Background
Dry eye syndrome is a common health problem in the adult population. Many risk factors including age, sex, prior eye surgery, various chronic diseases, and lifestyle factors can affect its development. We have evaluated the risk of dry eye syndrome based on the frequency of coffee consumption among Korean adult population.
Methods
A total of 9,752 adults with age 19 years and older were randomly selected between 2010 and 2012. They have all participated in the National Health and Nutrition Examination Survey V of Korea. Dry eye syndrome was being diagnosed by the physicians at some points in the participant’s lifetime. The average daily coffee intake was divided into the following: less than 1 cup, 1 to 2 cups, and 3 cups or more. Various physio-environmental factors and medical conditions were used as correction variables to assess the risk of dry eye syndrome in relation to the frequency of coffee consumption.
Results
The prevalence of dry eye syndrome decreased to 9.2%, 8.8%, and 6.3% as coffee consumption increased from less than 1 cup to 1–2 cups and more than 3 cups, respectively. However, there was no significant relationship between the frequency of coffee consumption and the risk of dry eye syndrome after adjusting various risk factors.
Conclusion
There is no relationship between the frequency of coffee consumption and risk of dry eye syndrome.

Citations

Citations to this article as recorded by  
  • The Relationship Between Caffeine Intake and Dry Eye Disease
    Morten Schjerven Magno, Tor P. Utheim, Mathias Kaurstad Morthen, Harold Snieder, Nomdo M. Jansonius, Christopher J. Hammond, Jelle Vehof
    Cornea.2023; 42(2): 186.     CrossRef
  • TFOS Lifestyle: Impact of societal challenges on the ocular surface
    Fiona Stapleton, Juan Carlos Abad, Stefano Barabino, Anthea Burnett, Geetha Iyer, Kaevalin Lekhanont, Tianjing Li, Yang Liu, Alejandro Navas, Chukwuemeka Junior Obinwanne, Riaz Qureshi, Danial Roshandel, Afsun Sahin, Kendrick Shih, Anna Tichenor, Lyndon J
    The Ocular Surface.2023; 28: 165.     CrossRef
  • TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface
    Anat Galor, Alexis Ceecee Britten-Jones, Yun Feng, Giulio Ferrari, David Goldblum, Preeya K. Gupta, Jesus Merayo-Lloves, Kyung-Sun Na, Shehzad A. Naroo, Kelly K. Nichols, Eduardo M. Rocha, Louis Tong, Michael T.M. Wang, Jennifer P. Craig
    The Ocular Surface.2023; 28: 262.     CrossRef
  • TFOS Lifestyle: Impact of nutrition on the ocular surface
    Maria Markoulli, Sumayya Ahmad, Jayashree Arcot, Reiko Arita, Jose Benitez-del-Castillo, Barbara Caffery, Laura E. Downie, Katie Edwards, Judith Flanagan, Marc Labetoulle, Stuti L. Misra, Malgorzata Mrugacz, Sumeer Singh, John Sheppard, Jelle Vehof, Piera
    The Ocular Surface.2023; 29: 226.     CrossRef
  • Modifiable lifestyle risk factors for dry eye disease
    Michael T.M. Wang, Alex Muntz, Brinda Mamidi, James S. Wolffsohn, Jennifer P. Craig
    Contact Lens and Anterior Eye.2021; 44(6): 101409.     CrossRef
  • 7,554 View
  • 133 Download
  • 5 Web of Science
  • 5 Crossref
The Relationship of Caffeine Intake with Depression, Anxiety, Stress, and Sleep in Korean Adolescents
Mi-Joo Jin, Chang-Ho Yoon, Hae-Jin Ko, Hyo-Min Kim, A-Sol Kim, Ha-Na Moon, Seung-Pi Jung
Korean J Fam Med 2016;37(2):111-116.   Published online March 25, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.2.111
Background

In various studies in adults, caffeine may increase wakefulness and relieve pain, but caffeine overdose can cause many adverse serious effects on health. Caffeine intake has recently been increasing in adolescents. In spite of importance of caffeine effects on Korean adolescents, there are lack of scientific and systematic studies. The purpose of our study was to identify the relationship between caffeine consumption and effects on adolescents.

Methods

We performed study on 234 middle school students at one middle school in Daegu using a self-report questionnaire. We divided students to quartiles according to amount of caffeine intake. We used Beck Depression Inventory (BDI) to evaluate the degree of depression and Beck Anxiety Inventory (BAI) to evaluate the degree of anxiety. We also used Insomnia Severity Scale (ISI) to evaluate the degree of insomnia and Global Assessment of Recent Stress (GARS) to evaluate the stress in students. We used logistic regression analysis to identify the relationship between caffeine consumption and effects.

Results

Higher caffeine intake was associated with higher weight, height, lower academic achievement, and higher score in BDI, BAI, ISI, and GARS (P for trend <0.005). Higher caffeine intake quartile was associated with greater odds of having significant depression (BDI ≥10, P for trend=0.011), and insomnia (ISI ≥8, P for trend=0.015) after adjustment for factors that can affect the psychological status.

Conclusion

We found that caffeine intake is associated weight, height, academic achievement, and higher score in BDI, BAI, ISI, and GARS. Caffeine intake was positively associated with the severity of depression and the severity of insomnia among adolescents in Korean.

Citations

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    Nutrients.2025; 17(7): 1155.     CrossRef
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    Nutrients.2025; 17(7): 1153.     CrossRef
  • Comparative Study of Middle and High School Students on the Relationship between High-Caffeine Drinks and Mental Health
    Jeeyeon PARK, Haesun YUN
    Korean Journal of Health Promotion.2025; 25(1): 29.     CrossRef
  • Fear/Anxiety and Sleep Deprivation Combine to Predict Courage
    Jeffrey A. Gibbons, Brenna E. McManus, Ella C. White, Akihaya M. Gibbons
    Behavioral Sciences.2025; 15(5): 634.     CrossRef
  • Patterns and prevalence of depression, tobacco, and caffeine use among university students from different majors in Lebanon: a cross-sectional study
    Afife El Hashem, Angela Bou Saba, Anna Maria Bou Madi, Caroline Mahfouz, Clara Derian, Elie El Husseiny, Jeanne-Marie Hanna, Maguy El Hayek, Shafika Assaad
    Frontiers in Public Health.2025;[Epub]     CrossRef
  • The association of dietary components with depression and anxiety symptoms: findings from a cross-sectional survey
    Kerri M. Gillespie, Eva Kemps, Melanie J. White, Selena E. Bartlett
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Energy drinks, depression, insomnia and stress among Palestinians: The mediating role of cigarettes smoking, electronic cigarettes and waterpipe
    Fayez Mahamid, Dana Bdier, Basma Damiri
    Journal of Ethnicity in Substance Abuse.2024; 23(4): 823.     CrossRef
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    Mashta Ikram, Hafiz Muhammad Shahbaz, Waqas Ahmed, Zahra Khan, Sajid Khan Tahir, Kashif Akram
    Topics in Clinical Nutrition.2024; 39(1): 33.     CrossRef
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    MoezAlIslam E. Faris, Eman Rashid Saif, Eman Ali Turki, Dana N. Abdelrahim, Salma Abu-Qiyas, Katia Abi Shihab, Falak Zeb, Haydar Hasan, Mona S. Hashim, Hadia M. Radwan, Farah Naja, Leila Cheikh Ismail, Tareq M. Osaili, Hanin Kassem, Radhiya Al Rajaby, Kha
    European Journal of Nutrition.2024; 63(2): 549.     CrossRef
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    Chen Liu, Licheng Wang, Chi Zhang, Ziyi Hu, Jiayi Tang, Junxian Xue, Wenchun Lu
    Frontiers in Psychology.2024;[Epub]     CrossRef
  • The caffeine dilemma: unraveling the intricate relationship between caffeine use disorder, caffeine withdrawal symptoms and mental well-being in adults
    Mahmut Bodur, Seda Kaya, Merve Ilhan-Esgin, Funda Pınar Çakiroğlu, Ayşe Özfer Özçelik
    Public Health Nutrition.2024;[Epub]     CrossRef
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    Journal of Functional Foods.2024; 115: 106101.     CrossRef
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    Naciye Çınar, Mustafa Topkafa
    Fullerenes, Nanotubes and Carbon Nanostructures.2024; 32(10): 953.     CrossRef
  • Excessive caffeine use and its consequence on mental illness: a cross-sectional study in Indonesia
    M Marthoenis, M Jannah
    IOP Conference Series: Earth and Environmental Science.2024; 1356(1): 012046.     CrossRef
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    Ashten R. Duncan, Sarah Beth Bell, Chan M. Hellman
    Current Psychology.2023; 42(26): 22301.     CrossRef
  • Trigger Factors of Consuming Tea and Coffee in University Students
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    Pakistan BioMedical Journal.2023; : 22.     CrossRef
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    JMIR Public Health and Surveillance.2023; 9: e46289.     CrossRef
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    Mediterranean Journal of Nutrition and Metabolism.2022; 15(2): 253.     CrossRef
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    Sleep Medicine Reviews.2022; 62: 101587.     CrossRef
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    Subin Park, Yeeun Lee, Junghyun H. Lee
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Caffeine Consumption and Its Related Symptoms in University Students.
Byung Hun Lee, Yong Soon Park, Jun Su Kim, Jun Hyun Yoo, Jung Kwon Lee
J Korean Acad Fam Med 2007;28(1):9-16.   Published online January 10, 2007
Background
: Although caffeine is commonly consumed substance and not seriously harmful as compared to alcohol and nicotine, Korea is planning to mark on the products which contain caffeine above a definite level with "containing large amounts caffeine". At this point in time, the study concerning caffeine related symptoms is in need.

Methods : After surveying university students by using self-administered questionnaires based on DSM-IV substance related disorder, healthy 810 subjects were assessed for socio-demographic characteristics and features of caffeine intake and its dependence, withdrawal, and intoxication.

Results : The mean amount of caffeine consumption in 810 subjects was 120.49 mg (median=93.0) per day. The major features of caffeine dependence were as follows: tolerance (61.1%), withdrawal (46.3%), using more or longer than intended (46.0%), and unsuccessful attempt to cut down or control use (12.6%). The prevalence was increased by daily caffeine consumption. Among 711 subjects who had experienced no caffeine consumption over 24 hours {amount of daily caffeine consumption was 116.0 mg (median=86.5)}, 6.19% showed significant distress in usual activity, and 22.1% used caffeine contents to avoid withdrawal symptoms. The prevalence of caffeine withdrawal based on DSM-IV research criteria was 2.67% and the frequency for symptoms were as follows: fatigue (37.7%), drowsiness (17.6%), headache (14.5%), an anxiety (8.3%). In addition, the prevalence of caffeine intoxication was 2.1% and the frequency for symptoms were as follows: insomnia (41.9%), diuresis (35.8%), tachycardia (26.7%), and gastrointestinal disturbance (23.3%).

Conclusion : The unwanted symptoms related to caffeine withdrawal or intoxication were common in students using caffeine. Therefore, major features of caffeine-related symptoms should be considered in primary care practice.
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