Background This study aimed to evaluate the association between complementary and alternative medicine (CAM) use and fear of cancer recurrence (FCR) among breast cancer survivors, using a validated multidimensional FCR-assessing instrument. Despite the debate over its medical effects, the use of CAM in breast cancer survivors is increasing.
Methods We recruited 326 breast cancer survivors who had completed the primary cancer treatment. Information on CAM use was obtained using a self-administered questionnaire, and FCR was assessed using the Korean version of the FCR Inventory (FCRI). Multivariate linear regression analysis was performed to evaluate the association between CAM use and FCR.
Results CAM users had higher total FCR scores than CAM non-users after covariate adjustment (CAM users: 74.6 vs. CAM non-users: 68.7; P=0.047). Among the FCRI subscales, CAM users showed higher coping strategy scores (CAM users: 22.3 vs. CAM non-users: 20.6; P=0.034) in the multivariable adjusted analysis. The use of multiple types of CAM was associated with increased FCR in a dose-dependent manner (P=0.002).
Conclusion Breast cancer survivors who used CAM had a higher FCR than CAM non-users. The dose-response relationship between the use of multiple types of CAM and FCR suggests that breast cancer survivors who use multiple types of CAM should be provided with appropriate psychological interventions to decrease FCR.
Citations
Citations to this article as recorded by
Use of complementary health approaches and research interests among older adults in the COSMOS trial Dennis Muñoz-Vergara, Yan Ma, EunMee Yang, Sarah Jaehwa Park, Wren M. Burton, Eunjung Kim, JoAnn E. Manson, Gloria Y. Yeh, Peter M. Wayne, Howard D. Sesso The American Journal of Medicine.2026; 139(8): 1065. CrossRef
Associations between Fear of Cancer Recurrence and Health-Related Quality of Life, Psychological Distress, and Health Behaviors in Cancer Survivors Seo-Hee CHOI, Yeol KIM, Yu-Ri CHOE Korean Journal of Health Promotion.2025; 25(3): 99. CrossRef
Critical Considerations Regarding the Article “Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors” Niloufar Johari Varnoosfaderani, Ehsan Amiri-Ardekani Korean Journal of Family Medicine.2023; 44(1): 66. CrossRef
Use of complementary and alternative medicine for reducing fear of cancer recurrence among cancer survivors: Does it work? Heliang Wu, Adnan Rashid Aziz, Mahlagha Dehghan, Leyla Ahmadi Lari, Rasmieh Al-Amer, Mohammad Ali Zakeri Asia-Pacific Journal of Oncology Nursing.2023; 10(10): 100278. CrossRef
Adherence to lifestyle recommendations among Norwegian cancer survivors and the impact of traditional and complementary medicine use: the Tromsø Study 2015–2016 Kiwumulo Nakandi, Faith O. Benebo, Laila A. Hopstock, Trine Stub, Agnete E. Kristoffersen BMC Complementary Medicine and Therapies.2023;[Epub] CrossRef