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"Gender Difference"

Original Articles
Low bone mineral density is associated with high-frequency hearing impairment in women over 50: an observational study in Korea
Sang-Hoon Lee, Seung-Soo Lee, Hun-Yi Park, Bom-Taeck Kim
Korean J Fam Med 2025;46(6):418-425.   Published online November 14, 2024
DOI: https://doi.org/10.4082/kjfm.23.0130
Background
Osteoporosis and hearing impairment are known to be associated, but specific data regarding gender, bone mineral density (BMD) measurement sites, and hearing frequency ranges remain unclear. This study aimed to clarify the relationship between hearing loss and BMD in adults over the age of 50. Additionally, the study sought to determine the frequency ranges of pure tone audiometry (PTA) related to osteoporosis, identify BMD measurement sites, and investigate gender differences.
Methods
A total of 1,523 adults (651 men and 872 women) over the age of 50, who participated in a medical health check-up at a university hospital, were included. PTA was conducted to assess hearing, and BMD was measured using dual-energy X-ray absorptiometry at the lumbar vertebrae (LV) and femur.
Results
In women over the age of 50, a significant association was observed between hearing impairment and osteoporosis (P<0.01), but no such association was found in men. Lumbar BMD (L1–4) in women was significantly associated with hearing loss at 4,000 and 8,000 Hz (both P<0.05), whereas femoral neck and total femur BMD showed no significant relationship. In multiple logistic regression analysis, the odds ratio (OR) between osteoporosis and hearing threshold at 4,000 Hz (OR, 2.078; 95% confidence interval [CI], 1.092–3.954) and 8,000 Hz (OR, 2.648; 95% CI, 1.543–4.544) remained statistically significant in women after adjusting for age and other risk factors.
Conclusion
In women over the age of 50, low BMD at the LV is significantly associated with hearing impairment, particularly at the high frequencies of 4,000 and 8,000 Hz.

Citations

Citations to this article as recorded by  
  • Towards early detection and prevention: proactive screening strategies in primary care
    Su Hwan Cho
    Korean Journal of Family Medicine.2025; 46(6): 379.     CrossRef
  • 2,818 View
  • 75 Download
  • 1 Web of Science
  • 1 Crossref
Background
Diet and physical activity are key factors related to depressive mood. Previous studies have demonstrated the effects of diet and physical activity on depression. However, the effect of energy intake-expenditure balance (EIEB) on mental health has not been fully evaluated. This study aimed to analyze the association between EIEB and depression.
Methods
A total of 13,460 participants (5,660 men and 7,800 women) aged ≥19 years were obtained from the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey (KNHANES). EIEB was defined as the difference between the daily energy intake and energy expenditure. Energy intake was calculated and provided by the KNHANES using a 24-hour recall survey. Energy expenditure was estimated as the sum of basal metabolic rate and physical activity. Logistic regression analyses were used to investigate the association between sex-specific quartile groups (Q1–Q4) of EIEB and depression after adjusting for socioeconomic status, body mass index, lifestyle factors, and underlying diseases.
Results
Women in Q3 of EIEB (211–669 kcal) had a significantly lower risk of depression (odd ratio [OR], 0.78; 95% confidence interval [CI], 0.67–0.92) than those in Q1 of EIEB (<-167 kcal). The adjusted ORs of depression were 0.87 (95% CI, 0.75–1.02) in Q2 and 0.86 (95% CI, 0.74–1.01) in Q4, with P for trend=0.030. There were no significant associations between the EIEB quartile groups and depression in men after adjusting for potential confounders (P for trend=0.564).
Conclusion
Our results suggested that the EIEB is negatively associated with depression in Korean women.

Citations

Citations to this article as recorded by  
  • A Lower Energy Balance is Associated With Higher Severity and Odd of Depression Based on the Beck Depression Inventory‐13 (BDI‐13) in a Retiring Age Population: A Population‐Based Cross‐Sectional Study
    Mohammad Reza Shadmand Foumani Moghadam, Mostafa Shahraki Jazinaki, Zohre Hosseini, Fatemeh Rajabi, Sharif Etemdi, Melika Hadizadeh, Parnian Pezeshki, Mohammad Amushahi, Reza Rezvani
    Health Science Reports.2025;[Epub]     CrossRef
  • Dietary patterns of Filipino older adults and associated factors: analysis of the 2013 National nutrition survey and 2018–2019 expanded National nutrition survey
    Robby Carlo Tan, Kyler Kenn Castilla, Michael Serafico, Marco Mensink, Lisette CPGM de Groot
    BMC Geriatrics.2025;[Epub]     CrossRef
  • Women’s Health and Primary Care
    Seung-Won Oh
    Korean Journal of Family Medicine.2024; 45(1): 1.     CrossRef
  • Gender Difference in the Impact of Total Energy Intake on the Association between Low Fiber Intake and Mental Health in Middle-Aged and Older Adults
    Sinyoung Cho, Minseon Park
    Nutrients.2024; 16(16): 2583.     CrossRef
  • 5,146 View
  • 108 Download
  • 5 Web of Science
  • 4 Crossref
Gender Difference in the Level of HDL Cholesterol in Korean Adults
Hye Jin Kim, Hyun Ah Park, Young Gyu Cho, Jae Heon Kang, Kyoung Woo Kim, Joo Ho Kang, Nu-Ri Kim, Won-Chin Chung, Cheol Hwan Kim, Dong Hee Whang, Jin Kyun Park
Korean J Fam Med 2011;32(3):173-181.   Published online March 31, 2011
DOI: https://doi.org/10.4082/kjfm.2011.32.3.173
Background

High density lipoprotein (HDL) cholesterol level varies with ethnicity and gender. In Korea there has not been an agreement on standards for HDL cholesterol level. Therefore, in order to establish a foundation for research on HDL cholesterol, we investigated the gender difference in HDL cholesterol level after adjusting associated factors.

Methods

The study population included 4,465 individuals (1,833 men, 2,632 women) representing 33,502,918 Koreans 20 years of age or older, who participated in the 2005 Korean National Health and Nutrition Survey. After stratifying by gender, we analyzed the HDL cholesterol level according to the general characteristics of the study population. Then we identified independent factors associated with HDL cholesterol level. After adjusting for covariates, we estimated the gender difference in HDL cholesterol level.

Results

We demonstrated that age, current smoking, body mass index, alcohol intake, triglyceride and low density lipoprotein cholesterol level have significant impact on HDL cholesterol level. In addition, educational status was also an important factor for men, while fat intake was a significant factor for women. After adjusting associated factors, the means (standard errors) of HDL cholesterol level were 43.8 (0.2) mg/dL in men and 46.3 (0.2) mg/dL in women, respectively.

Conclusion

The mean gender difference in HDL level (2.5 mg/dL) in Korean adults was, therefore, less than those observed in previous western studies.

Citations

Citations to this article as recorded by  
  • Lipid Abnormalities and Their Association with Obesity and Hypertension Among Young Adults in Delhi-NCR, India
    Oishi Choudhury, Seyielenuo Suokhrie, Kallur Nava Saraswathy, Vineet Chaudhary, Naorem Kiranmala Devi
    Obesity Medicine.2025; 53: 100581.     CrossRef
  • The potential of the serum uric acid to high-density lipoprotein cholesterol ratio as a predictive biomarker of diabetes risk: a study based on NHANES 2005–2018
    Jianming Yin, Chuanjie Zheng, Xiaoqian Lin, Chaoqiang Huang, Zhanhui Hu, Shuyuan Lin, Yiqian Qu
    Frontiers in Endocrinology.2025;[Epub]     CrossRef
  • Gender Difference in Cardiovascular Diseases Risk Factors and Scores among Health Workers: A Cross-sectional Study Based on the Cohort Study of Iran
    Seyed Jalil Masoumi, Mehrab Sayadi, Fariba Moradi Ardekani, Armin Attar, Atefeh Torabi, Leila Jamali, Maryam Yoosefinia, Fatemeh Jafari
    Research in Cardiovascular Medicine.2025; 14(1): 40.     CrossRef
  • Gender correlation between sleep duration and risk of coronary heart disease: a systematic review and meta-analysis
    Cun Li, Shun-xin Luo, Tian-wei Liang, Dan Song, Jin-xiao Fu
    Frontiers in Cardiovascular Medicine.2025;[Epub]     CrossRef
  • Evaluating the Effectiveness of Moxibustion in Hyperlipidemia: A Systematic Review and Meta-Analysis
    Mohammad A. Jareebi, Abdulsalam Humedi, Asayel Darraj, Jana Alsyrawan, Alwaleed Bamanie, Salman Alghamdi, Albaraa Marzuqi, Majd Al-matrafi, Dana Alharbi, Areej Barnawi, Jalal Abu Halimah, Aisha H. Majrashi, Amani Saad Alsriha, Adhari A. Alselmi, Ghadeer A
    Medical Principles and Practice.2025; : 1.     CrossRef
  • Dyslipidemia among adult people living with HIV on dolutegravir – based antiretroviral therapy at a private tertiary hospital in Kampala, Uganda: burden and determinants
    Vianney John Kigongo, Joaniter I. Nankabirwa, Freddy Eric Kitutu, Ronald Ssenyonga, Ronald Kasoma Mutebi, Andrew Kazibwe, Ronald Kiguba, Andrew D. Kambugu, Barbara Castelnuovo
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • Association of atherosclerosis indices, serum uric acid to high‐density lipoprotein cholesterol ratio and triglycerides‐glucose index with hypertension: A gender‐disaggregated analysis
    Rana Kolahi Ahari, Toktam Sahranavard, Amin Mansoori, Zahra Fallahi, Negin Babaeepoor, Gordon Ferns, Majid Ghayour‐Mobarhan
    The Journal of Clinical Hypertension.2024; 26(6): 645.     CrossRef
  • A Cross-Sectional Observational Study to Assess the Efficacy of Triglyceride to High-Density Lipoprotein Ratio as a Marker of Insulin Resistance in Subjects of Central Rural India
    Khalid Khan, Sabiha Quazi, Nandkishor J Bankar, Anil Wanjari, Rajesh Gosavi, Prashant Joshi, Sunil Gupta
    Cureus.2024;[Epub]     CrossRef
  • Prognostic Value of Monocyte-to-High-Density Lipoprotein Cholesterol Ratio in COVID-19 Patients
    Celal Kilit, Türkan Paşalı Kilit, Sertaş Erarslan
    Journal of Contemporary Medicine.2024; 14(6): 315.     CrossRef
  • 20-Year Trends in Metabolic Syndrome Among Korean Adults From 2001 to 2020
    Dahyun Park, Min-Jeong Shin, Jean-Pierre Després, Robert H. Eckel, Jaakko Tuomilehto, Soo Lim
    JACC: Asia.2023; 3(3): 491.     CrossRef
  • Sex difference in lipid levels in first-diagnosed drug-naïve depression patients: A case-control and 12-weeks follow-up study
    Rui Yang, Lu Wang, Song Cao, Ming Chen, Chu-Jun Wu, Floyd Silva, Man-Jun Shen, Jin-Dong Chen, Mi-Mi Tang, Bi-Lian Liu
    The World Journal of Biological Psychiatry.2022; 23(3): 228.     CrossRef
  • The Current Status of Research on High-Density Lipoproteins (HDL): A Paradigm Shift from HDL Quantity to HDL Quality and HDL Functionality
    Kyung-Hyun Cho
    International Journal of Molecular Sciences.2022; 23(7): 3967.     CrossRef
  • Interactive effects of the low‐carbohydrate diet score and genetic risk score on Hypo‐HDL‐cholesterolemia among Korean adults: A cross‐sectional analysis from the Ansan and Ansung Study of the Korean Genome and Epidemiology Study
    SoHyun Park, Min‐Jae Jang, Min Young Park, Jun‐Mo Kim, Sangah Shin
    Food Science & Nutrition.2022; 10(9): 3106.     CrossRef
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    Elisa Dietrich, Anne Jomard, Elena Osto
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
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    Elham Razmpoosh, Shima Abdollahi, Mahdieh Mousavirad, Cain C. T. Clark, Sepideh Soltani
    Diabetology & Metabolic Syndrome.2022;[Epub]     CrossRef
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    Lina Albitar
    Heliyon.2022; 8(12): e12195.     CrossRef
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    Nafiseh Shokri-Mashhadi, Sajjad Moradi, Hamed Mohammadi, Abed Ghavami, Mohammad Hossein Rouhani
    European Journal of Cardiovascular Nursing.2021; 20(6): 588.     CrossRef
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    Giovanni Mario Pes, Yong-Moon Park, Gian Pietro Sechi
    Neurology.2021; 96(10): 465.     CrossRef
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    Metabolites.2021; 11(5): 326.     CrossRef
  • Rapid Decrease in HDL-C in the Puberty Period of Boys Associated with an Elevation of Blood Pressure and Dyslipidemia in Korean Teenagers: An Explanation of Why and When Men Have Lower HDL-C Levels Than Women
    Kyung-Hyun Cho, Jae-Ryong Kim
    Medical Sciences.2021; 9(2): 35.     CrossRef
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    Yu-Huei Li, Chieh-Hua Lu, Fu-Huang Lin, Sheng-Chiang Su, Jhih-Syuan Liu, Chang-Hsun Hsieh, Yi-Jen Hung, Yi-Shing Shieh, Chien-Hsing Lee
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    Tsui-Wen Hsu, Disline Manli Tantoh, Kuan-Jung Lee, Oswald Nfor Ndi, Long-Yau Lin, Ming-Chih Chou, Yung-Po Liaw
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    Resuscitation.2019; 145: 26.     CrossRef
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    Huan-Cheng Chang, Chuan-Fa Hsieh, Disline Manli Tantoh, Pei-Chieh Ko, Ya-Yu Kung, Mei-Chi Lin, Yi-Ching Liaw, Yung-Po Liaw
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    Journal of Cardiovascular Nursing.2017; 32(6): 514.     CrossRef
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The Role of C-reactive Protein as a Inflammation-related Factor in Metabolic Syndrome.
Jeon Su Park, Yun Jin Kim, Jeong Gyu Lee, Young Joo Kim, Sangyeoup Lee, Hong Gi Min, Byung Mann Cho
Korean J Fam Med 2009;30(6):449-456.   Published online June 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.6.449
Background
The metabolic syndrome has been known as the cluster of insulin resistance, dyslipidemia, hypertension, and abdominal obesity. There have been many studies about the infl ammatory role in atherosclerosis and cardiovascular diseases, also. We aimed to elucidate the role of high sensitivity C-reactive protein (hs-CRP) as a infl ammation-related factor in metabolic syndrome in Korean adults by correlation and factor analysis. Methods: A cross sectional study was carried out in 1,512 men and 1,836 women (over 20 years old) who had an examination at a center for health promotion of an university hospital from May 2004 through March 2005. The NCEP-ATP III definition and Asian-Pacific adjusted criteria were used to obtain the metabolic syndrome group. And we evaluated the role and gender difference of hs-CRP in metabolic syndrome by correlation and factor analysis.Results: In women, hs-CRP was statistically correlated with most metabolic variables, especially insulin resistance. In factor analysis, 3 factors (obesity, blood pressure, and insulin resistance) were obtained in men and 4 factors (obesity, blood pressure, insulin resistance, and dyslipidemia) in women, respectively. In women, hs-CRP was a part of dyslipidemia factor.Conclusion: In factor anaylsis of metabolic syndrome factors with hs-CRP, hs-CRP was not a signifi cant factor in men, but was included as a part of dyslipidemia factor in women.

Citations

Citations to this article as recorded by  
  • The Relationship between Metabolic Syndrome Risk Factors and High Sensitive C-reactive Protein in Abdominal Obesity Elderly Women
    Kyung-A Shin
    The Korean Journal of Clinical Laboratory Science.2017; 49(2): 121.     CrossRef
  • Clinical Outcomes after Modified Fasting Therapy Supplied with Gamrosu: A Retrospective Observational Study
    Seung-Uoo Shin, Dong-Hwan Kim, Hyun-Taeg Shin, Dal-Seok Oh
    Journal of Korean Medicine for Obesity Research.2016; 16(1): 36.     CrossRef
  • 2,960 View
  • 26 Download
  • 2 Crossref
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