Korean Journal of Family Medicine

"Geriatrics"

Review Article

The Impact of Pharmacist Medication Reviews on Geriatric Patients: A Scoping Review: Nor Liana Che Yaacob, Mathumalar Loganathan, Nur Azwa Hisham, Habibah Kamaruzzaman, Khairil Anuar Md Isa, Mohamed Izham Mohamed Ibrahim, Kwok-Wen Ng; Korean J Fam Med 2024;45(3):125-133. Published online April 5, 2024; DOI: https://doi.org/10.4082/kjfm.23.0220; Correction in: Korean J Fam Med 2024;45(4):235

Medication review is an intervention with the potential to reduce drug-related problems (DRPs) in the elderly. This study aimed to determine the effect of pharmacists’ medication reviews on geriatric patients. This study accessed two online databases, MEDLINE Complete and Scopus, and examined all studies published in English between 2019 and 2023, except for reviews. The studies included (1) participants over 65 years of age and (2) medication reviews conducted by pharmacists. The titles, abstracts, and full texts were reviewed for data extraction to determine whether the studies satisfied the inclusion and exclusion criteria. Forty-four of the initial 709 articles were included in this study. The articles included discussions on the incidence rates of DRPs and potentially inappropriate medications (PIMs) (n=21), hospitalization (n=14), medication adherence (n=9), quality of life (QoL) (n=8), and falls (n=7). Pharmacist medication reviews were associated with a reduced incidence of DRPs and PIMs, and improved adherence to medications. Patients’ overall QoL is also increasing. However, pharmacist medication reviews were not strongly associated with decreased hospitalization or falls. A pharmacist’s medication review may be a feasible intervention for reducing the incidence rates of DRPs and PIMs, regardless of whether it is performed as a sole intervention or supplemented with other interventions. The intervention was also effective in increasing medication adherence and QoL.

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Quality of prescribing and health-related quality of life in older adults: a narrative review with a special focus on patients with atrial fibrillation and multimorbidity
Cheima Amrouch, Deirdre A. Lane, Amaia Calderón-Larrañaga, Mirko Petrovic, Delphine De Smedt
European Geriatric Medicine.2025; 16(4): 1137. CrossRef
Effectiveness of Pharmacist Interventions in Improving Medication Use in Hospitalised Older Patients Diagnosed With Cardiovascular Diseases: INFAR Before‐and‐After Study
Romana Santos Gama, Luiz Carlos Passos, Welma Wildes Amorim, Renato Morais Souza, Marcio Galvão Oliveira
Journal of Evaluation in Clinical Practice.2025;[Epub] CrossRef
A Systematic Review of Long-Term Use of Proton Pump Inhibitors (PPIs) in Older Adults on Polypharmacy: Do PPIs Deplete Nutrients?
Muhammad Salman Shahid, Nouman Ahmed, Zeeshan Kamal, Laibah Nathaniel, Bhavna Singla, Shivam Singla, Sunita Kumawat, Munaza Batool, Osatohanmwen Ekomwereren, Nabila N Anika, Muhammad Sahil
Cureus.2025;[Epub] CrossRef
Erratum: The Impact of Pharmacist Medication Reviews on Geriatric Patients: A Scoping Review
Nor Liana Che Yaacob, Mathumalar Loganathan, Nur Azwa Hisham, Habibah Kamaruzzaman, Khairil Anuar Md Isa, Mohamed Izham Mohamed Ibrahim, Kwok-Wen Ng
Korean Journal of Family Medicine.2024; 45(4): 235. CrossRef
Application of the Statin-Associated Muscle Symptoms-Clinical Index to a Cohort of Patients with Type 2 Diabetes Mellitus Undergoing Phlebotomy at an Endocrinology Clinic
Nor Humaira Mohd Tajudin, Mathumalar Loganathan Fahrni, Rohana Abdul Ghani, Mohd Hazriq Awang, Hitesh Chopra, Ali Saleh Alkhoshaiban
Journal of Pharmacology and Pharmacotherapeutics.2024; 15(4): 389. CrossRef
Contribución de los Farmacéuticos Comunitarios en la detección y notificación de reacciones adversas en Andalucía
Miguel Romero Pérez, Manuel Sánchez Polo, José Alberto Ayala Ortiz, Blanca Contreras Aguilar, María José Zarzuelo-Romero
Ars Pharmaceutica (Internet).2024; 66(1): 25. CrossRef

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Original Articles

Risk Factors Related to Serious Adverse Drug Reactions Reported through Electronic Submission during Hospitalization in Elderly Patients: Seon-Hye Won, Sang-Yeon Suh, Eunji Yim, Hong-Yup Ahn; Korean J Fam Med 2022;43(2):125-131. Published online March 17, 2022; DOI: https://doi.org/10.4082/kjfm.21.0086

Background
Many studies have assessed the risk factors for adverse drug reactions (ADRs) in elderly patients. However, most of these studies have focused on risk factors for ADRs, not serious ADRs (s-ADRs). s-ADRs are commonly found in hospitalized patients. s-ADRs warrant imminent but thorough investigations, given their critical impact on patient health. Therefore, this retrospective study aimed to assess the associated risk factors for s-ADRs in elderly hospitalized patients.
Methods
In-patients aged >65 years having ADRs during hospitalization at a university hospital in Korea between 2010 and 2012 were included. Medical professionals spontaneously reported ADRs using an electronic submission system at the study hospital. Further, all descriptions of ADRs were characterized and categorized through the screening of electronic medical records. We compared the characteristics of patients having s-ADRs with those of patients not having s-ADRs.
Results
There were 353 cases of ADRs, 67 of which were s-ADRs. Patients taking more than eight concomitant drugs showed the highest odds ratio (OR, 11.99; 95% confidence interval [CI], 3.42–42.03). The ratio of aspartate aminotransferase (AST)/alanine aminotransferase (ALT) was also significantly related to s-ADRs (OR, 2.78; 95% CI, 1.33–5.81). The use of antibiotics (OR, 2.39; 95% CI, 1.13–5.02) and antineoplastics (OR, 4.17; 95% CI, 1.09–15.94) were significant risk factors.
Conclusion
Our findings highlight the importance of polypharmacy. Liver function tests (AST/ALT ratio) must be monitored carefully within high-risk groups for ADRs.

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Risk factors for severe adverse drug reactions in hospitalized patients
Nemanja Z. Petrović, Ana V. Pejčić, Miloš N. Milosavljević, Slobodan M. Janković
Open Medicine.2025;[Epub] CrossRef
Drug-Induced Serious Cutaneous Reactions in Hospitalized Patients: A Cross-Sectional Study
Warisara Jiamsathit, Kansuda Bunarong, Sonthiya Papenkort, Anthony R. Cox, Narumol Jarernsiripornkul
Journal of Clinical Medicine.2025; 14(3): 857. CrossRef
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Sopit Sittiphan, Apiradee Lim, Haris Khurram, Nurin Dureh, Kwankamon Dittakan, Obed Kwabena Offe Amponsah
PLOS ONE.2025; 20(2): e0318597. CrossRef
Potential inappropriate medications and drug–drug interactions in adverse drug reactions in the elderly: a retrospective study in a pharmacovigilance database
Huaqiao Jiang, Yanhua Lin, Weifang Ren, Lina Lu, Xiaofang Tan, Xiaoqun Lv, Ning Zhang
Frontiers in Pharmacology.2025;[Epub] CrossRef
Implementation of a line of care for older adults in a teaching hospital
Lisiane Manganelli Girardi Paskulin, Roberta Rigo Dalla Corte, Helena Barreto dos Santos, Bruno Simas da Rocha, Francine Melo da Costa, Simone Augusta Finard, Tiago Oliveira Teixeira, Renato Gorga Bandeira de Mello
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Lisiane Manganelli Girardi Paskulin, Roberta Rigo Dalla Corte, Helena Barreto dos Santos, Bruno Simas da Rocha, Francine Melo da Costa, Simone Augusta Finard, Tiago Oliveira Teixeira, Renato Gorga Bandeira de Mello
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Porrawee Pramotesiri, Krongtong Putthipokin, Sirasa Ruangritchankul
Journal of Clinical Medicine.2024; 13(6): 1638. CrossRef
Exploring the community pharmacist’s knowledge, attitude, and practices regarding adverse drug reactions and its reporting in the United Arab Emirates: a survey-based cross-sectional study
Javedh Shareef, Sathvik Belagodu Sridhar, Mullaicharam Bhupathyraaj, Atiqulla Shariff, Sabin Thomas
Therapeutic Advances in Drug Safety.2024;[Epub] CrossRef
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Jungun Lee
Korean Journal of Family Medicine.2022; 43(2): 91. CrossRef

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Association between Female Urinary Incontinence and Geriatric Health Problems: Results from Korean Longitudinal Study of Ageing (2006): Kyungjin Sohn, Chang Ki Lee, Jinyoung Shin, Jungkwon Lee; Korean J Fam Med 2018;39(1):10-14. Published online January 23, 2018; DOI: https://doi.org/10.4082/kjfm.2018.39.1.10

Abstract
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Background

Urinary incontinence (UI) is highly prevalent in the aging population. UI is one of the most common geriatric syndromes and affects overall health, quality of life, and economical burden in patients. The aims of this study were to investigate the characteristics of patients with UI and to assess its association with other geriatric health problems.

Methods

We used data from the Korean Longitudinal Study of Ageing obtained in 2006. Among the 10,254 individuals aged 45 years and older, we analyzed data from 2,418 women aged 65 years and older. Data were obtained using questionnaires for UI, comorbidities, and lifestyle factors.

Results

Among the 2,418 women aged 65 years and older, 506 (20.9%) had UI. Cerebrovascular disease (odds ratio [OR], 2.02; 95% confidence interval [CI], 1.26 to 3.23), arthritis (OR, 1.44; 95% CI, 1.18 to 1.77), and fear of falling (OR, 1.62; 95% CI, 1.18 to 2.22) were significantly associated with UI, while chronic lung disease, psychiatric disease, difficulty in daily living due to visual and hearing problems, and experiencing a fall in the last 2 years were not associated with UI.

Conclusion

Cerebrovascular disease, arthritis, and especially fear of falls were significantly associated with UI in elderly Korean women.

Citations

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Qinggang Liu, Linna Wang, Limin Liao, Huiling Cong, Yi Gao
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Older women with urinary incontinence have higher prevalence of dynapenia: A cross-sectional study
Luis Fernando Ferreira, Jéssica Roda Cardoso, Priscilla Dalenogare, Cislaine Machado de Souza, Gabriela Tomedi Leites, Luis Henrique Telles da Rosa, Patrícia Viana da Rosa
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Patchareepon Chompoowisate, Sumattana Glangkarn, Chaloemporn Namyota
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Raquel Santana Bernardes, Regina de Sousa Barros, Felipe Sousa da Silva, Serise Amaral Pequeno, Aline Teixeira Alves, Patrícia Azevedo Garcia
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Raquel Santana Bernardes, Regina de Sousa Barros, Felipe Sousa da Silva, Serise Amaral Pequeno, Aline Teixeira Alves, Patrícia Azevedo Garcia
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Danielle Scharp, Sarah E. Harkins, Maxim Topaz
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Eda Yakit Ak, Umran Oskay
International Journal of Urological Nursing.2022; 16(2): 157. CrossRef
Efeito da incontinência urinária na autopercepção negativa da saúde e depressão em idosos: uma coorte de base populacional
Marciane Kessler, Pâmela Moraes Volz, Janaína Duarte Bender, Bruno Pereira Nunes, Karla Pereira Machado, Mirelle de Oliveira Saes, Mariangela Uhlmann Soares, Luiz Augusto Facchini, Elaine Thumé
Ciência & Saúde Coletiva.2022; 27(6): 2259. CrossRef
Prevalence and factors related to urinary incontinence in older adults women worldwide: a comprehensive systematic review and meta-analysis of observational studies
Sedighe Batmani, Rostam Jalali, Masoud Mohammadi, Shadi Bokaee
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The impact of urinary incontinence on falls: A systematic review and meta-analysis
Shinje Moon, Hye Soo Chung, Yoon Jung Kim, Sung Jin Kim, Ohseong Kwon, Young Goo Lee, Jae Myung Yu, Sung Tae Cho, Peter F.W.M. Rosier
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Jungun Lee
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Urinary incontinence in resident women in nursing homes
Isabel C. R. V. Santos, Jair L. dos Santos Júnior, Tayne F. L. da Silva, Natália M. S. de Albuquerque, Jabiael C. da Silva Filho, Marilia P. Valença
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Shelagh M. Szabo, Katherine L. Gooch, David R. Walker, Karissa M. Johnston, Adrian S. Wagg
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Geriatrics in Family Medicine Residency Program: Training Conditions and Suggestions.: Bodri Son, Chang Won Won, Il Sin Kim, Hyun Rim Choi, Byung Sung Kim; J Korean Acad Fam Med 2008;29(9):687-694. Published online September 10, 2008

Abstract
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Background: With the number of geriatric population on a steep increase, the roles of family physicians broaden to give comprehensive medical care to the elderly. Therefore, geriatrics is becoming increasingly more important for the residents of family medicine. The authors have surveyed and researched on resident's current attention, actual training conditions, and future needs on geriatrics. Methods: Family medicine residents in 79 hospitals registered to Korean Family Medicine Resident Union were enrolled. By means of electronic and postage mail surveys, informations were gathered; including demographics, the order of importance of nine training curricula, the necessity of training itself, the facility and academic conference of geriatrics training. Results: A total of 173 residents in 45 hospitals replied with return rates of 51.9%. Among the total, 169 (97.7%) of the answered agreed on the necessity of geriatrics training. Of the nine curricula, geriatrics was considered the most important. And residents considered family medicine outpatient department and inpatient ward to be the most important place for geriatrics training. Furthermore, the residents considered elderly's diseases or symptoms as more important conference title, but the parameters such as the quality of life, physiology of aging, care in nursing home were considered less important. Conclusion: The geriatrics training program is not up to the standards of residents' satisfaction. This is considered to be due to the absence of a formal training program. To provide a better care for the elderly, it is compulsory to gain broad knowledge of geriatrics and actual experience out in the field. (J Korean Acad Fam Med 2008;29:687-694)

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The Effect of Water Exercise on Stress Relief in the Aged.: Yong Jun Park, Youn Seon Choi, Myung Ho Hong, Jung Hyun Kim, Jeong A Kim, Dae Young Kim, Do Kyung Yoon, Kee Un Choi, Kyung Ok Yi; J Korean Acad Fam Med 2002;23(10):1202-1209. Published online October 10, 2002