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"Health-Related Quality of Life"

Original Articles
Association of Thyroid Status with Health-Related Quality of Life in Korean Older Adults
Minjung Han, Seulggie Choi, Sarang Kim, Ahryoung Ko, Joung Sik Son, Sang Min Park
Korean J Fam Med 2020;41(1):38-44.   Published online January 6, 2020
DOI: https://doi.org/10.4082/kjfm.19.0054
Background
While hypothyroidism is associated with negative health effects in the general population, older adults with hypothyroidism have better physical function and comparable rates of depression and cognitive impairment relative to their euthyroid counterparts. The aim of this study was to investigate the association between thyroid status and health-related quality of life in Korean older adults.
Methods
In this population-based cross-sectional study, 1,060 adults aged over 60 years were classified by thyroid status into four groups based on their thyroid stimulating hormone (TSH) and free T4 values: overt hypothyroid, subclinical hypothyroid, euthyroid, and subclinical hyperthyroid. The main outcome measure was self-reported health-related quality of life based on the three-level version of the EuroQol-5 dimension (EQ-5D), with utility values of -0.171 and 1.000 corresponding to the worst and best health statuses, respectively. The adjusted means of the EQ-5D three-level version utility values according to thyroid status were determined using a linear regression analysis.
Results
In the adjusted analysis, the overt hypothyroid group showed significantly higher EQ-5D three-level version utility values than did the euthyroid group (0.998 vs. 0.908, P=0.000). In the subgroup analyses by sex, the overt hypothyroid group also showed significantly higher EQ-5D three-level version utility values for both men and women than did the euthyroid group (0.998 vs. 0.940, P=0.008; 0.983 vs. 0.882, P=0.001).
Conclusion
Asymptomatic Korean older adults aged over 60 years with TSH and free T4 values corresponding to overt hypothyroidism have better health-related quality of life than their euthyroid counterparts.

Citations

Citations to this article as recorded by  
  • Cost-effectiveness Analysis Comparing Conventional and Digital Software Supported Management for Hypothyroidism
    Jung Hyun Kim, Jaeyong Shin, Man S Kim, Jae Hoon Moon
    The Journal of Clinical Endocrinology & Metabolism.2025; 110(6): 1596.     CrossRef
  • Correlation of gender with health related-quality of life of patients in 13 groups of disease in Poland
    Marlena Krawczyk-Suszek, Arkadiusz Gaweł, Andrzej Kleinrok
    Scientific Reports.2025;[Epub]     CrossRef
  • Owners’ Experience and Satisfaction with Radioiodine Treatment in Hyperthyroid Cats—A Prospective Questionnaire Study
    Sofie Muthmann, Joana Léonie Tiefenbrunner, Fabienne Blunschi, Isabell Klemm, Natali Bettina Bauer, Katarina Hazuchova
    Veterinary Sciences.2025; 12(5): 458.     CrossRef
  • Prevalence and Risk Factors of Subclinical Hypothyroidism in Young and Middle‐Aged Patients With First‐Episode Drug‐Naïve Major Depressive Disorder
    Jiacheng Liu, Liying Yang, Chuanyi Kang, Xiaohong Wang, Na Zhao, Xiangyang Zhang, Drozdstoy Stoyanov
    Depression and Anxiety.2025;[Epub]     CrossRef
  • Comparison of the Changes in Quality-of-Life of Cats with Hyperthyroidism Treated with Radioiodine or Antithyroid Drugs—A Preliminary Study
    Fabienne Blunschi, Sofie Muthmann, Natali Bauer, Katarina Hazuchova
    Veterinary Sciences.2025; 12(6): 572.     CrossRef
  • Cost-Effectiveness of Proton Versus Photon Therapy for Medulloblastoma Using Updated Clinical Outcomes
    Chonnipa Nantavithya, Anussara Prayongrat, Wasin Laohavinij, Piti Techavichit, Khomsak Srilanchakon, Nattawan Utoomprurkporn, Maythinee Chantadisai, Chaisiri Wanlapakorn, Kanjana Shotelersuk
    International Journal of Particle Therapy.2025; 17: 100754.     CrossRef
  • Total Thyroidectomy and Quality of Life in Patients With Hashimoto Thyroiditis: A Systematic Scoping Review
    Marcus Sim, Emily Tan, Huiling Liew, Alvin Tan, Hao Li
    Journal of Surgical Research.2025; 316: 185.     CrossRef
  • The enigma of persistent symptoms in hypothyroid patients treated with levothyroxine: A narrative review
    Petros Perros, Christina Van Der Feltz‐Cornelis, Enrico Papini, Endre V. Nagy, Anthony P. Weetman, Laszlo Hegedüs
    Clinical Endocrinology.2023; 98(4): 461.     CrossRef
  • The Impact of Subclinical Hypothyroidism on the Quality of Life During Pregnancy: Mapping 5-Level Version of EQ-5D and ThyPRO-39
    Jan Tuzil, Barbora Filkova Pilnackova, Torquil Watt, Jan Jiskra, Marcela Koudelkova, Eva Novotna, Klara Tuzilova, Tomas Dolezal, Jana Bartakova
    Value in Health.2023; 26(7): 1085.     CrossRef
  • The Impact of Hypothyroidism on the Quality of Life of Adults in Riyadh, Saudi Arabia
    May I AlAwaji, Rana H Alhamwy
    Cureus.2023;[Epub]     CrossRef
  • Assessment of Quality of Life Among Patients With Primary Hypothyroidism: A Case-Control Study
    Ranya Ghamri, Raghad Babaker, Salwan Ezzat, Haya Alsaedi, Muruj Alkhamisi, Ragad Arbaein, Rahaf Alyahya, Shahad Fayraq, Sultan Alamri
    Cureus.2022;[Epub]     CrossRef
  • Association between Subclinical Thyroidism and Health Related Quality of Life: Based on the 6th Korea National Health and Nutrition Examination Survey
    Ho Soo Nam, Yeong Sook Yoon, Yun Jun Yang, Eon Sook Lee, Jun Hyung Lee, Hyo Sang Kook, Hyuk Jin Kwon
    Korean Journal of Family Practice.2022; 12(5): 333.     CrossRef
  • Cost-Effectiveness of Dronedarone and Amiodarone for the Treatment of Chinese Patients With Atrial Fibrillation
    Mengran Zhang, Yu Ren, Luying Wang, Jianhao Jia, Lei Tian
    Frontiers in Public Health.2021;[Epub]     CrossRef
  • 8,731 View
  • 155 Download
  • 11 Web of Science
  • 13 Crossref
Association between Body Mass Index and Quality of Life in Elderly People over 60 Years of Age
Gyeongsil Lee, Jiyoung Park, Seung-Won Oh, Hee-Kyung Joh, Seung-Sik Hwang, Jeehyun Kim, Danbee Park
Korean J Fam Med 2017;38(4):181-191.   Published online July 20, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.4.181
Background

The Korean population is aging rapidly and the number of health threats is increasing. The elderly obese population is also increasing and this study aimed to evaluate the association between body mass index (BMI) and health-related quality of life in the elderly Korean population.

Methods

The Korean version Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) was administered to elderly subjects (≥60 years) selected from welfare and health centers, and university hospitals. Sociodemographic information and subjects' height and weight were also recorded.

Results

The study population's mean age was 74.2±7.1 years, and the average BMI was 24.5±3.2 kg/m2. The 542 participants were segregated based on BMI quartiles. The SF-36 scores were compared among the sex-stratified quartile groups after adjusting for age, education level, income, smoking, alcohol, and arthritis diagnosis. The SF-36 scores were compared for four BMI quartiles stratified by sex, after adjusting for age, education level, income, smoking, alcohol consumption, and arthritis diagnosis. Men in the Q3 and Q4 groups had higher mental health scores than men in Q2 group. Additionally, men in the Q3 group had higher social function scores than those in the Q2 and Q4 groups. No differences were observed for the remaining six domains; no significant score differences were observed in any of the survey domains for the female subjects.

Conclusion

There was no significant association between a high BMI and a low quality of life in the elderly Korean population selected from hospitals and welfare centers, as assessed using the SF-36 scores.

Citations

Citations to this article as recorded by  
  • Overnutrition in the Elderly Population: Socio-Demographic and Behavioral Risk Factors in Hungary
    Battamir Ulambayar, Amr Sayed Ghanem, Attila Csaba Nagy
    Nutrients.2025; 17(12): 1954.     CrossRef
  • Pengaruh pengetahuan gizi dan status gizi terhadap kualitas hidup lansia di Posyandu Kampung Bambar, Kabupaten Jayapura
    Rosmin Mariati Tingginehe, Arius Togodly
    JURNAL KEPERAWATAN TROPIS PAPUA.2025; 8(1): 92.     CrossRef
  • The Role of Body Mass Index, Advanced Age, and Low Educational Attainment in Mild Cognitive Impairment among the Older Adult Population: A Study in a Rural Area in Indonesia
    Aulia Miladitiya, Achmad Zulfa Juniarto, Annta Kern Nugrohowati, Tri Indah Winarni
    Journal of Nutrition in Gerontology and Geriatrics.2023; 42(3-4): 144.     CrossRef
  • Automatic Segmentation of Periapical Radiograph Using Color Histogram and Machine Learning for Osteoporosis Detection
    Rini Widyaningrum, Enny Itje Sela, Reza Pulungan, Anindita Septiarini, Mario Dioguardi
    International Journal of Dentistry.2023; 2023: 1.     CrossRef
  • Quality of life profiles and their associations with depressive symptoms and cognitive impairment of community-dwelling older adults in Hong Kong
    Guozhi Luo, Weiping Li, Donghai Wu, Xinyue Wei, Yanpeng Zang, Jing-Dong Liu
    Frontiers in Public Health.2023;[Epub]     CrossRef
  • Association between Body Mass Index, Physical Activity and Quality of Life amongst Older People in Malaysia during COVID-19: A Cross-Sectional Analysis
    Nor Safura Mohd Noor, Nur Kamilah Mohd Fauzy, Sakinah Harith, Wan Rohani Wan Taib, Rosliza Yahaya, Almira Sitasari, Furaida Khasanah
    Malaysian Journal of Medicine and Health Sciences.2023; 19(6): 42.     CrossRef
  • The Impact of Obesity on the Health of the Older Population: A Cross-Sectional Study on the Relationship between Health-Related Quality of Life and Body Mass Index across Different Age Groups
    Patrick Reinbacher, Alexander Draschl, Maria Anna Smolle, Andrzej Hecker, Franz Gaderer, Kay-Bernd Lanner, Paul Ruckenstuhl, Patrick Sadoghi, Andreas Leithner, Stefan Nehrer, Thomas Klestil, Kevin Brunnader, Gerwin A. Bernhardt
    Nutrients.2023; 16(1): 51.     CrossRef
  • Distinct biological ages of organs and systems identified from a multi-omics study
    Chao Nie, Yan Li, Rui Li, Yizhen Yan, Detao Zhang, Tao Li, Zhiming Li, Yuzhe Sun, Hefu Zhen, Jiahong Ding, Ziyun Wan, Jianping Gong, Yanfang Shi, Zhibo Huang, Yiran Wu, Kaiye Cai, Yang Zong, Zhen Wang, Rong Wang, Min Jian, Xin Jin, Jian Wang, Huanming Yan
    Cell Reports.2022; 38(10): 110459.     CrossRef
  • New BMI Cut-Off Points for Obesity in Middle-Aged and Older Adults in Clinical Nutrition Settings in Italy: A Cross-Sectional Study
    Laura Di Renzo, Leila Itani, Paola Gualtieri, Massimo Pellegrini, Marwan El Ghoch, Antonino De Lorenzo
    Nutrients.2022; 14(22): 4848.     CrossRef
  • Social Activities and Health-Related Quality of Life in Rural Older Adults in South Korea: A 4-Year Longitudinal Analysis
    JiYeon Choi, Kyeongra Yang, Sang Hui Chu, Yoosik Youm, Hyeon Chang Kim, Yeong-Ran Park, Youn-Jung Son
    International Journal of Environmental Research and Public Health.2020; 17(15): 5553.     CrossRef
  • Association between body mass index and health-related quality of life among Chinese elderly—evidence from a community-based study
    Hua You, Xiao-lu Li, Kang-zhen Jing, Zhi-guang Li, Hong-mei Cao, Jin Wang, Lan Bai, Jing-hong Gu, Xiaoman Fan, Hai Gu
    BMC Public Health.2018;[Epub]     CrossRef
  • 8,958 View
  • 81 Download
  • 8 Web of Science
  • 11 Crossref
The Relation of Physical Activity to Helath Related Quality of Life.
Gye Hwa Lee, Cheol Hwan Kim, Ho Cheol Shin, Yong Woo Park, Eun Ju Sung
J Korean Acad Fam Med 2007;28(6):451-459.   Published online June 10, 2007
Background
Numerous studies have identified that physical activity influences decrements of both mortality and morbidity. Besides these objective indices, positive influences of physical activity on individuals' lives are being studied upon various populations. The purpose of this study was to evaluate the association of physical activity on health-related quality of life (HRQOL) in relatively healthy adults of Korea. Methods: Questionnaires were sent by mail to one thousand examinees who were scheduled for health check-up. We analyzed data from 214 men and 195 women. The physical activities were measured using the International Physical Activity Questionnaraire (IPAQ)-short form and the HRQOL was assessed by the CMCHS ver 1.0. The subjects were separated by gender and into either a recommended level of physical activity group or a lower physical activity group according to the physical activity scale. Results: The group with physical activity beyond the recommended level had better HRQOL measures than those who did not. After revising the factors that affected the HRQOL, cognition of present heath status, satisfaction for health status, bodily pain, physical function, emotional function, social function and general health measure scores were significantly higher in the female group with physical activity beyond recommended quantity than those who did not. However, there were no statical significance in the male group. Conclusion: Physical activity was associated with health related quality of life in middle aged women.
  • 2,052 View
  • 35 Download
The Relationship between Health Risk Appraisal and Health-related Quality of Life among Middle-aged Men.
Jung Il Jang, Cheol Hwan Kim, Ho Cheol Shin, Yong Woo Park, Eun Ju Sung, Eun Jung Lee, Da Hye Choi, Yu Jin Paik, Ae Jung Kim
J Korean Acad Fam Med 2006;27(7):534-539.   Published online July 10, 2006
Background
: Recently, several health risk appraisal programs have been developed to suit Korean character which is currently implemented. This study was conducted to find out the correlation with health age and health- related quality of life through health risk appraisal.

Methods : From March 1, 2004 to July 30, 2004, 107 male patients aged 30 to 59 who visited the family medicine clinic in a university hospital and had agreed to participate in the study have been assessed to determine the correlation between health age and health-related quality of life by measuring tools of health risk appraisal, CMCHS V1.0 questionnaire and Yangseng measurement questionnaire.

Results : Among the total 107 subjects, 3 were excluded because of incomplete questionnaire. There were 28 people aged in their thirties, 36 in forties, and 40 in fifties. The health age and health-related quality of life showed a negative correlation. The correlation in men in their life showed the strongest. Indexes between the health age and health perception, changes in health, vitality, morality Yangseng, diet Yangseng, sleep Yangseng and active and rest Yangseng have shown a strong negative correlation (P<0.05).

Conclusion : The lower the health age is, the better health- related quality of life in several domains of CMCHS V1.0 and Yangseng in middle aged Korean men.
  • 2,014 View
  • 20 Download
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