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Case Report

A Case Report of Male Systemic Lupus Erythematous with Antinuclear Antibodies-Negative: A Challenging Diagnosis
Ruziana Baharudin, Nur Suhaila Idris, Juliawati Muhammad, Wan Noor Hasbee Wan Abdullah
Korean J Fam Med 2022;43(2):150-154.   Published online March 17, 2022
DOI: https://doi.org/10.4082/kjfm.20.0211
Systemic lupus erythematosus (SLE) is a connective tissue disease of unknown etiology that predominantly affects women of childbearing age. We report a case of male systemic lupus erythematous with antinuclear antibodies and typical clinical presentations of multiple skin lesions, polyarticular joint pain, fatigue, anorexia, and hair loss. Full evaluations were used to establish a diagnosis of SLE. The lower prevalence of SLE among males and antinuclear antibody-negative patients poses a great challenge for diagnosis. Therefore, as primary care doctors, we need to have a high suspicion of systemic lupus erythematous even in male and antinuclear antibody-negative patients. Thus, early treatment may help patients improve their quality of life.

Citations

Citations to this article as recorded by  
  • Diagnostic Dilemma of ANA-negative Pediatric Systemic Lupus Erythematosus in a South Asian Female
    Qaisar Ali Khan, Tehmina khan, Parsa Abdi, Christopher Farkouh, Michelle Anthony, Faiza Amatul Hadi, Sumaira Iram
    Clinical Medicine Insights: Case Reports.2023;[Epub]     CrossRef
  • Unusual presentation of systemic lupus erythematosus in a male child: a case presentation
    Khyati Gupta, Vishal Dnyaneshwar Sawant, Sushma Save
    Egyptian Pediatric Association Gazette.2023;[Epub]     CrossRef
  • 5,380 View
  • 148 Download
  • 2 Web of Science
  • 2 Crossref
Original Articles
Effect of Increasing Tobacco Prices on Stages of Smoking Cessation: A Korean Nationwide Data Analysis
Jihye Kwon, Hyunji Kim, Hyoeun Kim, Sunmi Yoo, Seung Guk Park
Korean J Fam Med 2021;42(1):17-23.   Published online May 19, 2020
DOI: https://doi.org/10.4082/kjfm.19.0135
Background
In 2015, tobacco prices significantly increased in Korea as part of the government’s smoking cessation policy. This study examined the changes in the stages of smoking cessation among Korean male smokers before and after the implementation of the tobacco price policy, and identified the predictors of such changes.
Methods
The study population comprised 3,533 male current smokers (age ≥19 years) who participated in the Korea National Health and Nutrition Survey in 2012, 2013, 2015, and 2016. Current smokers were defined as persons who had smoked ≥100 cigarettes during their lifetime and are continuing to smoke. In accordance with the transtheoretical model, smokers were classified into the precontemplation stage (no plan to quit), contemplation stage, and preparation stage (planning to quit within 6 months). We examined the changes in the smoking cessation stages before and after the implementation of the policy. Multivariate logistic regression analysis was conducted to identify factors related to the likelihood of continuing smoking, after adjustments for potential confounders.
Results
Immediately after the policy implementation, the percentage of smokers in the precontemplation stage decreased from 65.6% to 60.8% (P=0.014). However, this effect was temporary. Significant risk factors for remaining in the precontemplation stage were older age (odds ratio [OR], 1.010; 95% confidence interval [CI], 1.002–1.018; P=0.004), being in the lowest income quartile (OR, 1.226; 95% CI, 1.001–1.502; P=0.049), and manual worker or unemployed status (OR, 1.256; 95% CI, 1.036–1523; P=0.020).
Conclusion
Increasing tobacco prices only temporarily change the stage of smoking cessation among Korean male smokers.

Citations

Citations to this article as recorded by  
  • Association Between Perceived Noise Pollution and Sleep Quality: Findings from the 2018 Community Health Survey
    Sujin Lee, Jae Ho Chung
    Noise and Health.2024; 26(122): 346.     CrossRef
  • Current status of tobacco use, cessation and control policy in Korea
    Cheol Min Lee
    Journal of the Korean Medical Association.2022; 65(12): 789.     CrossRef
  • Current status of health promotion in Korea
    Soo Young Kim
    Journal of the Korean Medical Association.2022; 65(12): 776.     CrossRef
  • Public Health Intervention for Smoking Cessation
    Soo Young Kim
    Korean Journal of Family Medicine.2021; 42(5): 343.     CrossRef
  • 4,011 View
  • 122 Download
  • 4 Web of Science
  • 4 Crossref
Association between Falls and Nutritional Status of Community-Dwelling Elderly People in Korea
Ah-Ra Jo, Mi-Jeong Park, Byung-Gue Lee, Young-Gyun Seo, Hong-Ji Song, Yu-Jin Paek, Kyung-Hee Park, Hye-Mi Noh
Korean J Fam Med 2020;41(2):111-118.   Published online March 19, 2020
DOI: https://doi.org/10.4082/kjfm.18.0112
Background
Malnutrition is a well-known risk factor of falls, although studies examining the association between nutritional status and falls are rare. We aimed to investigate the association between nutritional status and falls according to gender among Korean older adults.
Methods
The study included 10,675 participants (4,605 men and 6,070 women) aged 65 years and older and used data from the 2011 Survey of Living Conditions and Welfare Needs of Korean Older Persons. Nutritional status of the participants was assessed using the Nutritional Screening Initiative checklist, and the participants were categorized into the following groups: “good,” “moderate nutritional risk,” and “high nutritional risk.” Odds ratios (OR) of fall risk in the above groups based on gender were evaluated using multivariate logistic regression analyses.
Results
Fallers in both genders showed significant association with older age, lower household income, inadequate exercise, and poor nutritional status compared with non-fallers. Considering the good nutritional status group as the reference group, the high nutritional risk group showed a higher risk of falls in men (OR, 1.59; 95% confidence interval [CI], 1.26–1.99); both moderate and high nutritional risk groups showed a higher risk of falls after adjusting for confounding factors in women (OR, 1.39; 95% CI, 1.19–1.62 and OR, 1.90; 95% CI, 1.61–2.24, respectively).
Conclusion
The risk of falls was associated with poor nutritional status, and statistical significance of the association between nutritional status and falls was stronger in women than in men.

Citations

Citations to this article as recorded by  
  • Mapping sex and gender differences in falls among older adults: A scoping review
    Crista Sebastiani, Jamie Yee Xin Wong, Amandeep Litt, Julia Loewen, Karly Reece, Nicole Conlin, Tessa Dunand, Manuel Montero Odasso, Cassandra D'Amore, Stephanie Saunders, Marla Beauchamp
    Journal of the American Geriatrics Society.2024; 72(3): 903.     CrossRef
  • Temporal trends and the association between self-rated oral health and falls in community-dwelling older adults in South Korea: a secondary analysis of survey data
    Hyun-Ju Seo, Soon-Ki Ahn, Min-Jung Choi
    BMJ Open.2024; 14(4): e081549.     CrossRef
  • Age and Gender Differences in Fall-Related Factors Affecting Community-Dwelling Older Adults
    Minhee SUH, Da Hye KIM, Insook CHO, Ok Kyung HAM
    Journal of Nursing Research.2023; 31(2): e270.     CrossRef
  • Development of a protein energy malnutrition screening tool for older Thais in public residential homes
    Thitima Phodhichai, Warapone Satheannoppakao, Mathuros Tipayamongkholgul, Carol Hutchinson, Siriphan Sasat
    Public Health Nutrition.2022; 25(3): 565.     CrossRef
  • Current status of nutrient intake in Korea: focused on macronutrients
    Seung-Won Oh
    Journal of the Korean Medical Association.2022; 65(12): 801.     CrossRef
  • 5,770 View
  • 112 Download
  • 5 Web of Science
  • 5 Crossref
Association between Alcohol Consumption and Metabolic Syndrome Determined by Facial Flushing in Korean Women
Yu Ri Seo, Jong Sung Kim, Sung Soo Kim, Jin Gyu Jung, Seok Jun Yoon
Korean J Fam Med 2021;42(1):24-30.   Published online February 14, 2020
DOI: https://doi.org/10.4082/kjfm.19.0141
Background
This study aimed to examine the relationship between alcohol consumption and metabolic syndrome in Korean women as determined by facial flushing.
Methods
Of the female patients aged <65 years who visited the health promotion center at Chungnam National University Hospital from January 2016 to March 2017, 1,344 women were included. After adjusting for confounding factors such as age, body mass index, smoking, exercise, and menopausal status, multiple logistic regression analysis was performed to assess the association between alcohol consumption and the risk of metabolic syndrome in the facial flushing and non-facial flushing groups compared with the non-drinkers.
Results
Even after adjusting for confounding factors, the risk of metabolic syndrome was significantly high in all drinking subgroups (≤2 standard drinks: odds ratio [OR], 1.68; 95% confidence interval [CI], 1.10–2.68; 2<, ≤4 standard drinks: OR, 2.48; 95% CI, 1.29–4.74; and >4 standard drinks: OR, 4.16; 95% CI, 2.03–8.30) of the facial flushing group. The risk of metabolic syndrome was significantly high only in the subgroup of weekly alcohol consumption >4 standard drinks (OR, 2.20; 95% CI, 1.07–4.52) in the non-facial flushing group.
Conclusion
This study suggests that Korean women experiencing facial flushing when drinking have a higher risk of developing metabolic syndrome even with a low weekly drinking amount than those who do not experience face flushing.

Citations

Citations to this article as recorded by  
  • Microbiota for production of wine with enhanced functional components
    Armachius James, Ting Yao, Hengming Ke, Yousheng Wang
    Food Science and Human Wellness.2023; 12(5): 1481.     CrossRef
  • Current Status of Korean Alcohol Drinking in Accordance with the Korean Alcohol Guidelines for Moderate Drinking Based on Facial Flushing
    Sami Lee, Jihan Kim, Jong Sung Kim
    Korean Journal of Family Medicine.2023; 44(3): 129.     CrossRef
  • Association between Alcohol Consumption and Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Alcohol Flushing Response in Men: The Korea National Health and Nutrition Examination Survey 2019–2021
    Dae Eon Kang, Si Nae Oh
    Nutrients.2023; 15(18): 3901.     CrossRef
  • Alcohol and Testosterone Deficiency in People Who Experience Facial Flushes
    Jungun Lee
    Korean Journal of Family Medicine.2022; 43(6): 345.     CrossRef
  • Relationship between Alcohol Consumption and Testosterone Deficiency according to Facial Flushes among Middle-Aged and Older Korean Men
    Kyungmi Koh, Sung Soo Kim, Jong-Sung Kim, Jin-Gyu Jung, Seok-Joon Yoon, Won Yoon Suh, Hyun Gu Kim, Namhee Kim
    Korean Journal of Family Medicine.2022; 43(6): 381.     CrossRef
  • Does the Risk for Diabetes Related with Alcohol Drinking Depend on Facial Flushing?
    Soo Young Kim
    Korean Journal of Family Medicine.2020; 41(3): 137.     CrossRef
  • National Health Examination Metabolic Syndrome Item and Health Behavior Analysis
    Hyung-yeol Choi, Chang-hyun Jang, Soo-yeon Kim
    The Asian Journal of Kinesiology.2020; 22(4): 1.     CrossRef
  • 5,984 View
  • 157 Download
  • 6 Web of Science
  • 7 Crossref
Shift Work Is Associated with Metabolic Syndrome in Young Female Korean Workers
Kyoung Hwa Yu, Yu Hyeon Yi, Yun Jin Kim, Byung Mann Cho, Sang Yeoup Lee, Jeong Gyu Lee, Dong Wook Jeong, So Yeon Ji
Korean J Fam Med 2017;38(2):51-56.   Published online March 22, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.2.51
Background

Shift work is associated with health problems, including metabolic syndrome. This study investigated the association between shift work and metabolic syndrome in young workers.

Methods

A total of 3,317 subjects aged 20–40 years enrolled in the 2011–2012 Korean National Health and Nutrition Examination Survey were divided into shift and day workers. We conducted a cross-sectional study and calculated odds ratios using multivariate logistic regression analysis in order to examine the association between shift work and metabolic syndrome.

Results

The prevalence of metabolic syndrome was 14.3% and 7.1% among male and female shift workers, respectively. After adjusting for confounding factors, shift work was associated with metabolic syndrome in female workers (odds ratio, 2.53; 95% confidence interval, 1.12 to 5.70).

Conclusion

Shift work was associated with metabolic syndrome in young women. Timely efforts are necessary to manage metabolic syndrome in the workplace.

Citations

Citations to this article as recorded by  
  • Multimorbidity and its Associated Factors in Korean Shift Workers: Population-Based Cross-Sectional Study
    Hye Chong Hong, Young Man Kim
    JMIR Public Health and Surveillance.2024; 10: e55014.     CrossRef
  • Association between Sleep Duration, Social Jetlag, and the Metabolic Syndrome by Shift Works
    Minjung Kyung, Sungwon Park, Chang Gi Park, OiSaeng Hong
    International Journal of Environmental Research and Public Health.2024; 21(6): 668.     CrossRef
  • Association between Circadian Rhythm-Disturbing Factors and Metabolic Syndrome in Korean Adults: Korea National Health and Nutrition Examination Survey (2016–2020)
    Sujin Lee, Junhee Park, Hyunjin Cho, Jun Hyun Yoo
    Korean Journal of Family Medicine.2024;[Epub]     CrossRef
  • Association between Shift Work and Metabolic Syndrome: A 4-Year Retrospective Cohort Study
    Byeong-Jin Ye
    Healthcare.2023; 11(6): 802.     CrossRef
  • Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet
    Seán T. Anderson, Hu Meng, Thomas G. Brooks, Soon Yew Tang, Ronan Lordan, Arjun Sengupta, Soumyashant Nayak, Antonijo Mřela, Dimitra Sarantopoulou, Nicholas F. Lahens, Aalim Weljie, Gregory R. Grant, Frederic D. Bushman, Garret A. FitzGerald
    Science Translational Medicine.2023;[Epub]     CrossRef
  • Relationship between rotating shift work and white blood cell count, white blood cell differential count, obesity, and metabolic syndrome of nurses
    Wen-Pei Chang, Yen-Kuang Lin
    Chronobiology International.2022; 39(2): 159.     CrossRef
  • Metabolic syndrome and its relationship with shift work in petrochemical workers
    Payam Rashnuodi, Davood Afshari, Gholam Abbas Shirali, Arman Amiri, Marziye Raesi Zadeh, Ali Sahraneshin Samani
    Work.2022; 71(4): 1175.     CrossRef
  • The association between long-term night shift work and metabolic syndrome: a cross-sectional study of male railway workers in southwest China
    Chaohui Dong, Honglian Zeng, Bo Yang, Yi Zhang, Zhitao Li
    BMC Cardiovascular Disorders.2022;[Epub]     CrossRef
  • A systematic review and meta-analysis of the association between shift work and metabolic syndrome: The roles of sleep, gender, and type of shift work
    Masoud Khosravipour, Payam Khanlari, Sepideh Khazaie, Hadis Khosravipour, Habibolah Khazaie
    Sleep Medicine Reviews.2021; 57: 101427.     CrossRef
  • Association between shift work or long working hours with metabolic syndrome: a systematic review and dose–response meta-analysis of observational studies
    Yihui Wang, Li Yu, Yinyan Gao, Lili Jiang, Lin Yuan, Pengju Wang, Yanwen Cao, Xuping Song, Long Ge, Guowu Ding
    Chronobiology International.2021; 38(3): 318.     CrossRef
  • Association between shift work and risk of metabolic syndrome: A systematic review and meta-analysis
    Xingjin Yang, Wencheng Di, Yunhong Zeng, Dechen Liu, Minghui Han, Ranran Qie, Shengbing Huang, Yang Zhao, Yifei Feng, Dongsheng Hu, Liang Sun
    Nutrition, Metabolism and Cardiovascular Diseases.2021; 31(10): 2792.     CrossRef
  • Association between metabolic syndrome and shift work in chemical plant workers
    Seong-Ryol Chai, Soon-Chan Kwon, Yong-Jin Lee, Eun-Chul Jang, Young-Sun Min, Su-yeon Lee
    Annals of Occupational and Environmental Medicine.2021;[Epub]     CrossRef
  • Is Shift Work Sleep Disorder a Risk Factor for Metabolic Syndrome and Its Components? A Systematic Review of Cross-Sectional Studies
    Arpita Shah, Arifa Turkistani, Kanita Luenam, Sayma Yaqub, Patricia Ananias, Arunima Mariya Jose, Joao Pedro Melo, Lubna Mohammed
    Metabolic Syndrome and Related Disorders.2021;[Epub]     CrossRef
  • Metabolic syndrome: Association between prevalence and risk at worksites
    Michiru Kakinuma, Hiroo Ide, Kyoko Nakao, Daisuke Ichikawa, Ryozo Nagai, Yuji Furui
    Archives of Environmental & Occupational Health.2020; 75(4): 226.     CrossRef
  • Association between Dietary Habits, Shift Work, and the Metabolic Syndrome: The Korea Nurses’ Health Study
    Heeja Jung, Hyunju Dan, Yanghee Pang, Bohye Kim, Hyunseon Jeong, Jung Eun Lee, Oksoo Kim
    International Journal of Environmental Research and Public Health.2020; 17(20): 7697.     CrossRef
  • Shift work and metabolic syndrome: A multi‑center cross‑sectional study on females of reproductive age
    Maryam Nikpour, Aram Tirgar, Mahmod Hajiahmadi, Akram Hosseini, Behzad Heidari, Fatemeh Ghaffari, Abbas Ebadi, Fatemh Nasiri, Mojgan Firouzbakht
    Biomedical Reports.2019;[Epub]     CrossRef
  • Association between Metabolic Syndrome and Job Rank
    Ramin Mehrdad, Gholamreza Pouryaghoub, Mahboubeh Moradi
    The International Journal of Occupational and Environmental Medicine.2018; 9(1): 45.     CrossRef
  • The Relationship between Workplace Environment and Metabolic Syndrome
    Hwee-Soo Jeong
    The International Journal of Occupational and Environmental Medicine.2018; 9(4): 176.     CrossRef
  • Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health
    Santiago A. Plano, Leandro P. Casiraghi, Paula García Moro, Natalia Paladino, Diego A. Golombek, Juan J. Chiesa
    Frontiers in Neurology.2017;[Epub]     CrossRef
  • Shift Work and Health Problems
    Jungun Lee
    Korean Journal of Family Medicine.2017; 38(2): 49.     CrossRef
  • 5,764 View
  • 69 Download
  • 20 Web of Science
  • 20 Crossref
Prevalence and Predictive Factors of Sexual Dysfunction in Iranian Women: Univariate and Multivariate Logistic Regression Analyses
Ashraf Direkvand-Moghadam, Zainab Suhrabi, Malihe Akbari, Azadeh Direkvand-Moghadam
Korean J Fam Med 2016;37(5):293-298.   Published online September 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.5.293
Background

Female sexual dysfunction, which can occur during any stage of a normal sexual activity, is a serious condition for individuals and couples. The present study aimed to determine the prevalence and predictive factors of female sexual dysfunction in women referred to health centers in Ilam, the Western Iran, in 2014.

Methods

In the present cross-sectional study, 444 women who attended health centers in Ilam were enrolled from May to September 2014. Participants were selected according to the simple random sampling method. Univariate and multivariate logistic regression analyses were used to predict the risk factors of female sexual dysfunction. Diffe rences with an alpha error of 0.05 were regarded as statistically significant.

Results

Overall, 75.9% of the study population exhibited sexual dysfunction. Univariate logistic regression analysis demonstrated that there was a significant association between female sexual dysfunction and age, menarche age, gravidity, parity, and education (P<0.05). Multivariate logistic regression analysis indicated that, menarche age (odds ratio, 1.26), education level (odds ratio, 1.71), and gravida (odds ratio, 1.59) were independent predictive variables for female sexual dysfunction.

Conclusion

The majority of Iranian women suffer from sexual dysfunction. A lack of awareness of Iranian women's sexual pleasure and formal training on sexual function and its influencing factors, such as menarche age, gravida, and level of education, may lead to a high prevalence of female sexual dysfunction.

Citations

Citations to this article as recorded by  
  • Translation and investigation of the psychometric properties of the revised female sexual distress scale among Iranian couples
    Roghieh Bayrami, Hamid Sharif-Nia, Roksana Janghorban, Daniz Montakhabi Oskuii, Esmaeil Hoseinzadeh
    Scientific Reports.2025;[Epub]     CrossRef
  • Sexual dysfunction, marital relationship, and subjective quality of life among women with schizophrenia: Analytical case-control study
    Puja Kumari, Rajesh Kumar, Jitendra Rohilla
    Indian Journal of Psychiatry.2024; 66(3): 280.     CrossRef
  • The effect of rose damascene extract on anxiety and sexual function of breastfeeding women: a randomized controlled trial
    Gohar Akbarzadeh, Parvin Abedi, Shayesteh Jahanfar, Hossein Sadeghi Mansurkhani, Ahmad Fakhri, Elham Maraghi
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Sexual myths during pregnancy: a comparative study
    Hüsniye Dinç Kaya, Tülay Yılmaz, Sevil Günaydın, Emine Nur Çalımlı, Elham Sadeghi
    Journal of Obstetrics and Gynaecology.2022; 42(4): 587.     CrossRef
  • Impact of pelvic floor muscle strength on female sexual function: retrospective multicentric cross-sectional study
    Luísa Pasqualotto, Cássio Riccetto, Ana Flávia Biella, Joseane Marques, Larissa Carvalho Pereira, Fabíola Kênia Alves, Anna Lygia Barbosa Lunardi, Délcia Barbosa de Vasconcelos Adami, Anita Nagib, Natalia Martinho, Adriana Piccini, Tirza Sathler, Valeria
    International Urogynecology Journal.2022; 33(6): 1591.     CrossRef
  • The Effect of the PLISSIT Model on Sexual Functions: A Systematic Review
    Serap KIRICI, Emel EGE
    Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi.2021; 3(3): 199.     CrossRef
  • Sexual functions in pregnancy: different situations in near geography:a case study on Turkey, Iran and Greece
    Mahide Demireloz Akyuz, Esin Ceber Turfan, Serap Cetintas Oner, Tugce Sakar, Dilek Mamik Aktay
    The Journal of Maternal-Fetal & Neonatal Medicine.2020; 33(2): 222.     CrossRef
  • Effects ofWithania somniferaon Reproductive System: A Systematic Review of the Available Evidence
    Ramin Nasimi Doost Azgomi, Afshar Zomorrodi, Hossein Nazemyieh, Seyed Mohammad Bagher Fazljou, Homayoun Sadeghi Bazargani, Fatemeh Nejatbakhsh, Arezoo Moini Jazani, Yadollah Ahmadi AsrBadr
    BioMed Research International.2018; 2018: 1.     CrossRef
  • 4,578 View
  • 38 Download
  • 8 Web of Science
  • 8 Crossref
Development of a Simple Tool for Identifying Alcohol Use Disorder in Female Korean Drinkers from Previous Questionnaires
Yu Ri Seo, Jong Sung Kim, Sung Soo Kim, Seok Joon Yoon, Won Yoon Suh, Kwangmi Youn
Korean J Fam Med 2016;37(1):18-24.   Published online January 27, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.1.18
Background

This study aimed to develop a simple tool for identifying alcohol use disorders in female Korean drinkers from previous questionnaires.

Methods

This research was conducted on 400 women who consumed at least one alcoholic drink during the past month and visited the health promotion center at Chungnam National University Hospital between June 2013 to May 2014. Drinking habits and alcohol use disorders were assessed by structured interviews using the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition diagnostic criteria. The subjects were also asked to answer the Alcohol Use Disorders Identification Test (AUDIT), AUDIT-Consumption, CAGE (Cut down, Annoyed, Guilty, Eye-opener), TWEAK (Tolerance, Worried, Eye-opener, Amnesia, Kut down), TACE (Tolerance, Annoyed, Cut down, Eye-opener), and NET (Normal drinker, Eye-opener, Tolerance) questionnaires. The area under receiver operating characteristic (AUROC) of each question of the questionnaires on alcohol use disorders was assessed. After combining two questions with the largest AUROC, it was compared to other previous questionnaires.

Results

Among the 400 subjects, 58 (14.5%) were identified as having an alcohol use disorder. Two questions with the largest AUROC were question no. 7 in AUDIT, "How often during the last year have you had a feeling of guilt or remorse after drinking?" and question no. 5 in AUDIT, "How often during the past year have you failed to do what was normally expected from you because of drinking?" with an AUROC (95% confidence interval [CI]) of 0.886 (0.850–0.915) and 0.862 (0.824–0.894), respectively. The AUROC (95% CI) of the combination of the two questions was 0.958 (0.934–0.976) with no significant difference as compared to the existing AUDIT with the largest AUROC.

Conclusion

The above results suggest that the simple tool consisting of questions no. 5 and no. 7 in AUDIT is useful in identifying alcohol use disorders in Korean female drinkers.

Citations

Citations to this article as recorded by  
  • Screening for Alcohol Use in Pregnancy: a Review of Current Practices and Perspectives
    Danijela Dozet, Larry Burd, Svetlana Popova
    International Journal of Mental Health and Addiction.2023; 21(2): 1220.     CrossRef
  • 4,419 View
  • 27 Download
  • 1 Web of Science
  • 1 Crossref
The Association of Lung Age with Smoking Status in Korean Men
Hye Young Oh, Hong Soo Lee, Sang Wha Lee, Kyung Won Shim, Hyejin Chun, Joo Yeon Kim
Korean J Fam Med 2014;35(1):35-41.   Published online January 23, 2014
DOI: https://doi.org/10.4082/kjfm.2014.35.1.35
Background

Lung age, calculated from sex, forced expiratory volume in one second (FEV1), and height, was developed to illustrate premature changes to the lungs and could be used to motivate smoking cessation. However, this method has not been tested in association with smoking in Korea. The purpose of this study was to investigate the association of lung age with smoking and other factors in Korean males.

Methods

We reviewed the records of 1,100 healthy men who visited a health promotion center at Ewha Womans University Medical Center from January 2008 to June 2009. Lung age was calculated from FEV1 and normal predictive values of spirometry according to age in the Korean population. The difference between lung age and chronological age was evaluated in relation to smoking status, weight, body mass index, waist, muscle mass, fat mass, and exercise.

Results

The age difference was significantly higher in current smokers than in non-smokers (12.47 ± 19.90 vs. 7.30 ± 19.52, P < 0.001). Additionally, the age difference was positively correlated with life time pack-year (β = 0.223; P < 0.001) and fat mass (β = 0.462; P < 0.001). Lung age increased 1 year for 4.48 pack-year increase or for 2.16% increase in fat mass.

Conclusion

We found a significant relationship between lung age and both smoking status and fat mass in healthy Korean males. Lung age may be a useful tool for motivating cessation of cigarette smoking and management of risk factors related to obesity.

Citations

Citations to this article as recorded by  
  • Developing a predictive equation of muscular age to evaluate muscle health in Chinese community-dwelling older women
    Xiaoguang Zhao, Jiabin Yu, Nan Liu
    Health Care for Women International.2023; 44(12): 1587.     CrossRef
  • Effect of smoking status on spirometric lung age in adult Chinese Men
    Xiaoguang Zhao, Chenya Du
    Health & Social Care in the Community.2022; 30(4): 1384.     CrossRef
  • Comparison of periodontal status and salivary IL-15 and -18 levels in cigarette-smokers and individuals using electronic nicotine delivery systems
    Dena Ali, Isaac Kuyunov, Jagan Kumar Baskaradoss, Toshinari Mikami
    BMC Oral Health.2022;[Epub]     CrossRef
  • A pilot randomized controlled trial on the effectiveness of a ‘lung age’ intervention on smoking cessation: study protocol
    Imran Muhammad, Wenqi Mok, Hai Moy Toh, Daniel Sii, Wenru Wang
    Journal of Advanced Nursing.2015; 71(10): 2426.     CrossRef
  • 4,241 View
  • 41 Download
  • 10 Web of Science
  • 4 Crossref
The Functional Food Usage and Relation with Fatigue for Male Workers.
Sung Gon Lee, Sung Min Lee, Eun Hee Kong, Jong Soon Choi
Korean J Fam Med 2011;32(2):120-127.   Published online February 20, 2011
DOI: https://doi.org/10.4082/kjfm.2011.32.2.120
Background
Fatigue is a common problem in male workers as they have responsibilities in both role in home and in work place. The use of functional food has been one of the popular choices for fatigue recovery. This study was conducted to investigate the prevalence of functional food usage and its relationship with fatigue in male workers.Methods: The study subjects were male workers seen for health check up at a university hospital in Busan from May to July 2009. They completed a questionnaire including social factor, occupational factor, life style, functional food usage and disease status. The subjects were divided into groups according to fatigue severity.Results: Among 770 subjects, 267 (34.7%) consumed functional food daily. Most of them used functional food to recover fatigue as a supplement nutrition by their wife's or surrounding person's recommendation. There were significant difference between fatigue and non-fatigue group in age, occupation satisfaction, alcohol drinking, and insomnia. The prevalence of fatigue was 37.8%. The functional food usage significantly increased with fatigue severity scale (P < 0.001).Conclusion: Fatigue is common problem in male workers. The functional food usage is relation with fatigue severity.

Citations

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  • The Association between 10-Year Atherosclerotic Cardiovascular Diseases Risk Score Calculated Using 2013 American College of Cardiology/American Heart Association Guidelines and Serum 25-Hydroxyvitamin D Level among Aged 40–79 Years in Korea: The Sixth K
    Mun Hee Kim, Young Sang Kim, Hye Jin Oh, Yu Ri Kwon, Hye Won Kim
    Korean Journal of Family Medicine.2018; 39(3): 174.     CrossRef
  • Dietary Habits and the Perception and Intake of Health Functional Foods in Male Office Workers by Age
    Yun Hwa Hong, Eun Hee Lee, Hyun Sook Lim, Jong Hee Chyun
    Journal of the East Asian Society of Dietary Life.2015; 25(2): 340.     CrossRef
  • The relationship between Intake of Health Foods and Dietary Behavior in Middle-Aged Women
    Mi-Hee Kim, Hye-Jin Lee, Mi-Jeong Kim, Kyung-Hea Lee
    Korean Journal of Community Nutrition.2014; 19(5): 436.     CrossRef
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Relationship between Metabolic Syndrome and Aging Male Symptoms in Middle-Aged Males in Korea.
Gil Hyeoung Lee, Sung Goo Kang, Jin Hee Shin, Se Hong Kim, Jung Hyoun Cho, Seo Jin Park, Sang Wook Song
Korean J Fam Med 2010;31(8):613-621.   Published online August 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.8.613
Background
Metabolic syndrome is regarded as a risk factor of cardiovascular disease. We observed and compared aging males symptoms (AMS) between healthy and metabolic syndrome patients in middle-aged Korean men to evaluate clinical significance of AMS. Methods: From May 2009 to July 2009, 171 middle-aged men (over 40 years-old) who visited a health promotion center of a university hospital in Gyeonggi Province were enrolled in study. The subjects were divided into two groups; metabolic syndrome (N = 87) vs. control (N = 84) and measured the aging male symptoms (AMS) scale. AMS were also grouped according to its severity. Results: There were no significant differences except, weight, body mass index between two groups. In AMS severity, 'severe' group show higher prevalence of metabolic syndrome. And the group of metabolic syndrome gets higher AMS score than control. Among the five constitutive factors of metabolic syndrome, the prevalence of fasting blood sugar (≥ 100 mg/dL) and triglyceride (≥ 150 mg/dL) level is higher 'moderates' and 'severe' groups in AMS severity. In the subscale analysis of AMS, there are significant differences between two groups in sexual and somato-vegitative axis, but are not in psychological axis. With age-adjusted analysis, the results still show same trend.Conclusion: It might be necessary to approach aging males symptoms comprehensively during the management of metabolic syndrome in middle-aged men. And it could be helpful in treatment to recognize and control metabolic syndrome factors for the patients with severe aging males symptoms.
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Socioeconomic Factors Associated with Initiating and Quitting Cigarette Smoking Among Korean Men.
So Ra Kim, Ok Kil Kim, Kyung Eun Yun, Young Ho Khang, Hong Jun Cho
Korean J Fam Med 2009;30(6):415-425.   Published online June 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.6.415
Background
The prevalence of current cigarette smoking is the net result of different processes over the entire life course, namely initiation, continuation and cessation of smoking. This study examined the association of socioeconomic indicators with initiating and quitting smoking among South Korean men. Methods: We analyzed a total of 2,798 men aged 25-64 who participated in the Korean National Health and Nutrition Examination Survey in 2005. Odds ratios (ORs) with 95% confi dence intervals (CIs) for smoking initiation and cessation according to socioeconomic position indicators were calculated with logistic regression. Socioeconomic position was measured by education, occupation, income and marital status. Results: Greater rates of ever initiation of smoking were observed among lower educated men (OR = 1.51; 95% CI = 1.09-2.09) after controlling for other socioeconomic factors. Independent associations were found among men who performed manual labor (OR = 1.55; 95% CI = 1.12-2.14). After simultaneous adjustment for socioeconomic factors, lower likelihood of quitting smoking was detected among men who were in the middle third and the lower third income group (OR = 0.72; 95% CI = 0.55-0.92, OR = 0.60; 95% CI = 0.46-0.79, respectively), who performed manual labor (OR = 0.66; 95% CI = 0.50-0.86) or who were not married (OR for never-married = 0.65; 95% CI = 0.42-0.99 and OR for divorced or widowed = 0.56; 95% CI = 0.36-0.87, respectively). Conclusion: For Korean men, educational attainment was a strong predictor of ever initiating smoking, however, smoking cessation was independently related to income and marital status. To be effective, tobacco control interventions should consider these different social determinants in initiating and quitting smoking.

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Usefulness of Biomarkers to Screen Heavy Drinking in Korean Females.
Sang Wook Choi, Jong Sung Kim, Jin Gyu Jung, Sung Soo Kim, Seong Min Kim, Chul Sun Lim, Sun Hee Lee
J Korean Acad Fam Med 2008;29(6):412-417.   Published online June 10, 2008
Background
The present study purposed to evaluate the clinical usefulness of biological indicators in identifying Korean female heavy drinkers. Methods: Fifty five drinking women were selected among those who visited the Department of Family Medicine of Chungnam National University Hospital during the period from January to December 2006. We surveyed the alcohol intake during the recent one month. The correlation of alcohol intake with %CDT (carbohydrate- deficient transferrin), mean corpuscular volume (MCV), gamma glutamyl transferase (ՃGT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) was examined. The sensitivity, specificity, positive predictive value, negative predictive value and ROC (receiver operating characteristic) curve of the biomarkers for heavy drinking (more than 7 drinks per week, one drink= 14 g of alcohol) were also investigated. Results: The mean weekly alcohol intake showed a significant positive correlation with %CDT (r=0.583, P< 0.01), MCV (r=0.290, P<0.05) and AST (r=0.423, P<0.01). The sensitivity of %CDT, MCV, ՃGT, AST and ALT to heavy drinking were 66.7%, 13.3%, 40.0%, 26.7% and 26.7%, respectively, and the specificity 80.0%, 97.4%, 71.1%, 90.0% and 85.0%, respectively, and positive predictive values 55.6%, 66.6%, 35.3%, 50.0% and 40.0%, respectively, and negative predictive values 86.5%, 74.5%, 75.0%, 76.6% and 75.6%, respectively. The areas under the ROC curve (95% confidence interval) of %CDT, MCV, ՃGT, AST and ALT were 0.873 (0.780∼0.966), 0.806 (0.668∼0.944), 0.549 (0.372∼0.725), 0.519 (0.328∼0.710) and 0.479 (0.293∼0.666), respectively. Conclusion: %CDT is considered as the most useful marker for identifying Korean female heavy drinkers.(J Korean Acad Fam Med 2008;29:412-417)
  • 1,386 View
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The Relationship between Reduced Lung Function and High Sensitive C-reactive Protein in Healthy Adult Men.
Jung Un Lee, Yu Jin Paek
J Korean Acad Fam Med 2007;28(11):860-866.   Published online November 10, 2007
  • 1,253 View
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The Relationship between Waist Circumference/Height Ratio and Risk Factors of Cardiovascular Disease in Obese Females.
Seok Won Kim, Jae Hyeon Kwon, Jung Geum Yoon, Hyuck Ki Lee, Keun Mi Lee, Seung Pil Jung
J Korean Acad Fam Med 2004;25(10):740-745.   Published online October 10, 2004
Background
: In this study we estimated the prevalence of cardiovascular (CV) risk factors according to waist-to- height ratio (W/Ht ratio) in adult obese women to ensure the importance of abdominal obesity and determined the usefulness of W/Ht ratio as a index of abdominal obesity in adult obese women.

Methods : The study subjects were 190 adult obese women who visited an obesity clinic from August, 2001 to January, 2003. They were divided into 4 groups: Group 1; BMI<30, W/Ht<0.6, Group 2; BMI<30, W/Ht≥0.6, Group 3; BMI≥30, W/Ht<0.6, and Group 4; BMI≥30, W/Ht≥0.6. In each group, we compared the prevalence and odds ratio for CV risk factors.

Results : In obese group, the prevalence of high blood glucose (P<0.01), hypertriglyceridemia (P<0.01) were significantly higher in group 2 than group 1. In high obese group, the prevalence of systolic hypertension (P<0.01), high blood glucose (P<0.01), hypercholesterolemia (P<0.01), hypertriglyceridemia (P<0.05), and high LDL-cholesterol were significantly higher in group 4 than group 3. When odds ratio for each group with reference to group 1 were compared after adjusting for age, high blood glucose (4.48), and hypertriglyceridemia (6.10) in group 2, and systolic hypertension (2.69), high blood glucose (3.02), and hypertriglyceridemia (4.00) in group 4 were significantly higher.

Conclusion : The prevalence of CV risk factors were likely to be increased in higher W/Ht group independently to BMI. W/Ht ratio can be a simple, useful index for abdominal obesity and its related risk factors not only in adult males but also in adult obese women.
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A Study of Treatment Realities and Recognition of Male Osteoporosis.
Young Suk No, Tae Hwan Kwak, Soo Hyoun Chang
J Korean Acad Fam Med 2004;25(7):527-533.   Published online July 10, 2004
Background
: Osteoporosis has been thought of as a disease of women, but the incidence of male osteoporosis is increasing and is expected to keep rising due to alcohol abuse, smoking and increased life expectancy for men. This study was done to evaluate how many men recognized the significance of osteoporosis and its management.

Methods : There were 138 male subjects who underwent Bone Mineral Density (DEXA) from January 2000 to August 2003 at Sung Nam Central Hospital. We reviewed their BMD results and formed questionnaires which were constructed to evaluate men's recognition and treatment realities of osteoporosis. Telephone interviews and mailing services were utilized. The respondents were 96 (69.6%) and analysis was done.

Results : The average age of the 138 men was 55. Among them, there were 55 (39.9%) and 68 (49.3%) men who had been diagnosed with osteopenia and osteoporosis, respectively. Information on osteoporosis was obtained mainly from mass media like TV and newspaper (57.3% of total answers). The reason for undergoing test for osteoporosis was related to the annual screening tests (40.6% of total answers). Most of these people were likely to ignore the significance of osteoporosis, because only 26 percent answered they should receive proper treatment in case of osteoporosis although they did not have any symptoms at the time of the diagnosis. Among these osteoporotic patients, 76.7 percent did not seek any medical care and the most common reason for refusal to treatment was no existing symptoms for osteoporosis. Among the total, 67.4 percent of the patients said there had been no change of life behavior after the diagnosis.

Conclusion : We found that men had relatively more knowledge of osteoporosis than we expected, but they knew little about the need for treatment and possible severe complications like major fractures that may occur. Also, we found the diagnosis of osteoporosis has little effect on behavioral changes. In conclusion, family physicians should take more interest in the education of patients to increase compliance for its treatment.
  • 1,445 View
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Identification of Related Factors of Female Sexual Function in Family Medicine Outpatients.
Sang Yeon Suh, Taek Soo Shin, Taiwoo Yoo, Bong Yul Huh
J Korean Acad Fam Med 2003;24(8):721-730.   Published online August 10, 2003
Background
: Female sexual function is influenced by much more factors than that of male and has a close relationship with psychosocial factors. A satisfying sex life has a high correlation to a happy married life. A questionnaire provides easy access to private matters and in a multidimensional manner. The objective of this study was to identify the factors related to female sexual function to help sexual adjustment in marriage.

Methods : A hundred married women living with their spouses, who visited an outpatient clinic of family medicine department of a university hospital in Seoul were studied. After filling out the self-administered questionnaire, a face-to-face interview was done on all study subjects. For multivariate analysis of the related factors, the outcome variables were a binary response of the normal female sexual cycle ?drive, lubrication, orgasm, and satisfaction.

Results : The multivariate analysis showed that the household income was a significant factor related to Drive (Odds Ratio: OR=0.6, 95% Confidence Interval: CI 0.4∼0.9). Age was a significant factor related to Insufficient Lubrication (OR=1.1, 95% CI 1.0∼1.3). Insufficient foreplay was a risk factor for Insufficient Lubrication (OR= 2.4, P=0.052). In multivariate analysis of the Orgasm related factors, the perceived health status showed an OR of 7.1 (95% CI 1.5∼32.6) and both marital satisfaction and open communication showed an OR of 6.0 (95% CI 1.3∼26.8) and an OR of 5.8 (95% CI 1.2∼28.2), respectively. The significant related factors to Satisfaction were in order of importance of sex life, education, and open communication, with an OR of 3.6 (95% CI 1.7∼7.6), 2.5 (95% CI 1.1∼5.9), and 2.0 (95% CI 1.0∼3.8), respectively.

Conclusion : The positively related factors to female sexual function were good perceived health status, high marital satisfaction, placing importance in sex life, and open communication regarding sexual matters. Increasing age and household income were found to be factors adverse to female sexual function.
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Influence of HMG-CoA Reductase Inhibitors on Bone Mass in Postmenopausal Women.
Sang Yeoup Lee, Yun Jin Kim
J Korean Acad Fam Med 2003;24(5):451-455.   Published online May 10, 2003
Background
: It is controversial whether the use of HMG CoA reductase inhibitors (statins) is associated with an increased bone mineral density (BMD) in humans. The purpose of this study was to assess the influence of statins on BMD in Korean postmenopausal women.

Methods : Forty-four postmenopausal women (aged 54.3±5.8 years) were included. The statin users (n=24) were administered either simvastain, atorvastatin, pravastatin, or lovastatin. The control group (n=20) did not take statins. BMD of the spine were measured by dual-energy X-ray absorptiometry. Alkaline phosphatase (ALP) was tested as a bone marker. The data were analysed with two-sample t test and paired t-test.

Results : The mean annual spinal BMD changes of the study groups were -1.5±5.6% for statin users and -0.2±4.2% for control group. There was no statistically significant difference in mean annual spinal BMD changes (P=0.696). The mean annual ALP changes of the study groups were -5.6±18.1% for the statin users and -0.4±13.9% for the control group. There was no statistically significant difference in mean annual ALP changes (P=0.246). In each group, the spinal BMD significantly was not changed after 1 year (P>0.05).

Conclusion : This study suggest that statins do not protect from bone loss in Korean postmenopausal women.
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The Development of Female Sexual Function Questionnaire in Family Medicine Outpatients.
Sang Yeon Suh, Tai Woo Yoo, Bong Yul Huh
J Korean Acad Fam Med 2003;24(2):172-182.   Published online February 10, 2003
Background
: Currently, the high quality of life associated with women's rights is strongly supported and has become an important social issue. As a result, there is an increasing need for studies concerning female sexual function. The objectives of this study was to develop a questionnaire to evaluate sexual function evaluation in Korean women.

Methods : A total of 100 married women, who visited an outpatient clinic of family medicine department of a university hospital in Seoul, were studied. After filling out the self-administered questionnaire, a face-to- face interview was done on all study subjects. The items of this questionnaire were adopted from questionnaires with proven validity and reliability. Factor analysis was done and Crohnbach's alpha was calculated.

Results : The items of this questionnaire were classified into 5 parts: Drive, Excitement, Sexual activity, Satisfaction, and Spouse. The total variance was 51.5%. The total Crohnbach's alpha was 0.82. The internal consistency was high. Study subjects were able to complete this questionnaire within 10 minutes.

Conclusion : The validity and reliability of this female sexual function questionnaire was found to be acceptable. This questionnaire can be utilized as a diagnostic adjunctive tool and feedback for treatment through further studies.
  • 1,455 View
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The Association between Body Weight and Hypertension according to Smoking Status in Male Workers.
Ka Young Lee, Byung Mann Cho
J Korean Acad Fam Med 2002;23(5):613-619.   Published online May 31, 2002
Background
: The risk of hypertension increases as body weight is gained. In most studies, smoking has been considered as a confounder in association, but such association had not been analyzed between weight and the risk of hypertension varied according to smoking status.

Methods : The subject were 1,813 male worker who had routine bealth examination from April to June in 1998. They were divided into current smokers and non smokers according to smoking status and categorized into three different weight group; normal weight (BMI<23kg/m²), overweight(23≤BMI≤25 kg/m²) and obesity(BM≥25 kg/m²). Hypertension was defined if systolic blood pressure was ≥ 140 mmHg, or diastolic blood pressure was ≥ 90 mmHg. The interaction between smoking status and BMI for prevalence of hypertension, and the prevalence odds rations for hypertension among six groups categorized according to weight and smoking status, were analyzed by multiple logistic regression.

Results : The interaction between smoking status and BMI was significant (B=-0.058, SE=0.025, P=0.021). The risk of hypertension was 1.55 times (95% C.I 0.76~3.15) higher among the non-smokers with overweight and 2.90 times (95%) C.I. 1.01~4.32) higher among the non-smokers with obesity compared to the non-smokers with normal weight after controlling for age, serum glucose, and total cholesterol. In contrast, weight was not associated with the risk of hypertension among smokers.

Conclusion : The risk of hypertension rose as the weight of non-smokers increased. However, there was no association between the weight and the risk of hypertension among current smokers.
  • 1,412 View
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The relationship between physical fitness and fatigue among female employees in general hospitals.
Chan Hee Song, Jin Hee Shin, Kyoo In Chung, Keun Sang Yeum, Kyung Soo Kim
J Korean Acad Fam Med 2002;23(3):353-364.   Published online March 1, 2002
Background
: Physiological fatigue due to excessive physical activities and lack of proper rest is commonly observed among workers. Previous studies suggested that physiological fatigue can be related to individual physical fitness. This study was conducted to investigate the relationship between physical fitness and the degree of fatigue in 95 female employees in general hospitals.

Methods : Subjects were healthy adults female volunteers who were employed by two general hospitals located in Seoul and Kyunggido. The degree of fatigue using fatigue severity scale and physical fitness including % body fat, waist-hip ratio, maximal oxygen uptake, both grip strengths, back muscle strength, sit ups, flexibility, and broad jump were assessed. Data were strengths, back muscle strength, sit ups, flexibility, and broad jump were assessed. Data were analysed to examine the relationship between the degree of fatigue and each physical fitness.

Results : 1. Fatigue severity scale was significantly increased with increasing age and commuting time. Drinking alcohol was significantly related to increased fatigue severity scale.
2. Fatigue severity scale was significantly decreased with increasing number of family members and length of service.
3. Fatigue severity scale was significantly decreased with increasing both grip strengths, maximal O₂uptake, and sit ups.

Conclusion : The physical fitness factors including both grip strengths, maximal O₂uptake, and sit ups were considered to be important predictors in the evaluation of the degree of physiological fatigue.
  • 1,229 View
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The relationship between grip strength and radial BMD in middle aged men.
Young Ah Choi, In Suk Park, Moon Jong Kim, Kyung Gin Kim, Young Gon Kang, Ho Taek Lee, Young Jin Lee, Chul Young Bae
J Korean Acad Fam Med 2001;22(10):1520-1530.   Published online October 1, 2001
Background
: Although it has become obvious that male osteoporosis represent a public health issue, few studies has been done in Korea concerning the association between grip strength and bone mineral density(BMD) in men. This study was undertaken to enforce the necessity of muscle strengthening exercise program to improve BMD in middle-aged men by evaluate the association between grip strength and BMD.

Methods : The study was performed from January to December 1998 in the health screening center of CHA hospital with 174 men who measured both BMD and grip strength. BMD was measured at the proximal and distal radius of the dominant hand using Osteoplan p-DXA and grip strength was measured from the dominant hand using dynamometer. Daily calcium intake was measured through the interview with the diet therapist. Other datas were obtained from the questionnaire.

Results : We found a significant positive correlation between grip strength and BMD of distal and proximal radius(r=0.208; P<0.01, r=0.2555; P<0.01) and a significant negative correlation between age and BMD of distal and proximal radius(r=-0.313; P<0.01,r=-0.190; P<0.05). There was no correlation between calcium intake and BMD. BMI was correlated significantly only with BMD of distal Radius(r=0.194; P<0.05). There was no significant difference in BMD either by smoking or exercise. The multiple regression analysis showed that grip strength was independently correlated with BMD of the proximal radius significantly(β=1.731, P<0.05), but not with BMD of the distal radius after adjusting the confounding variables.

Conclusion : In conclusion, there is a significant correlation between grip strength and BMD in middle aged men. Therefore it can be safely concluded that it is helpful to carry out muscle strengthening program to improve muscle strength and increase BMD for preventing male osteoporosis.
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Relationship between total testosterone and serum lipid in middle aged men.
In Suk Park, Young Ah Choi, Moon Jong Kim, Sang Hyun Lee, Young Gon Kang, Ho Taek Lee, Young Jin Lee, Chul Young Bae
J Korean Acad Fam Med 2001;22(7):1126-1136.   Published online July 1, 2001
Background
: The prevalance of coronary heat disease is significantly higher in men than in premenopausal women of the same age. Impact that endogenous androgens have on serum lipid has many arguments and few researches were made in Korea. So this study was made to investigate correlation between total testosterone and serum lipid known as effect on cardiovascular disease.

Methods : This was a cross-sectional study on 560 middle aged men undertaken health screening program in Pundang General Hospital. Korea for June 1999 to June 2000. We surveyed informations concerning exercise, consumption of alcohol and smoking by means of self questionnaire records and total testosterone and serum lipid were measured at fasting state.

Results : Body mass index was positively correlated with total cholesterol and triglycerides(r=2.023;P<0.01, r=0.229;P<0.01) but negatively correlated with HDL-cholesterol (r=-0.284;P<0.001). Total testosterone concentrations were negatively correlated with total cholesterol and triglyceride(r=-0.096; P<0.05, r=-0.145; P<0.01) but positively correlated with HDL-cholesterol(r=0.155; P<0.001). Total testosterone concentrations were independently correlated with HDL-cholesterol after age and body mass index were adjusted(B=0.734; P<0.05). And after statistical adjustment for age, body mass index, exercise, smoking and alcohol, total, testosterone concentrations were significantly correlated with triglyceride(B=-10.467; P<0.05).

Conclusion : The result indicate that total testosterone can be a independent determinant of HDL-cholesterol and we expect that appropriate maintenance of total tetosterone concentrations will have a protective effect for cardiovascular disease.
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The effects of Cigarrete Smoking on Serum Lipid Profile in young-and middle-aged men.
Young Sung Suh
J Korean Acad Fam Med 1998;19(4):383-393.   Published online April 1, 1998
Background
: Cigarette smoking is a major risk factor for cardiovascular disease and a correctable risk factor. In middle and old-aged men, cardiovascular disease is in prevalence than at any other age. Most smokes, start smoking in their twenties and continued to do of that in middle and old aged men, especially in young-and middle-aged men. We examined the association between smoking and their level of plasma lipids.

Methods : Subjects were 238 healthy male non-smokers and 238 male smoker of 21-45 years of age, age matched, and were comparatively observed from May 1 to November 30, 1997 in a university hospital, Taegu, Korea. Subjects were interviewed by a research doctor who recorded subject's sociodemographic data, drinking amount, exercise, smoking status and smoking amount. We checked the level of serum total cholesterol, HDL-cholesterol, triglyceride on a fasting state and BMI.

Results : The results showed that smoking had a remarkable influence on HDL cholecterol, triglyceride, atherogenic index(ratio of total cholesterol to HDL cholesterol) between HDL cholesterol of smoking group in 31-35 year age group were obviously lower than nonsmoking that age group. The level of triglyceride in 31-35, 41-45 year age group were obviously higher than same nonsmoking groups. Atherogenic index in 31-35 year age group was obviously higher than nonsmoking that age group. But, no association between cigarette smoking and level of plasma total cholesterol was observed. HDL cholesterol, triglyceride, atherogenic index were significantly different beyond 11 pack-years or 20 cigarettes/day smoking groups than nonsmoking groups.

Conclusion : Based on the these findings, it is recommend that smoking cessation strategies for perceived healthy third decade and fourth decade men build up. I suggest smoking cessation education should start in the early age as soon as possible.
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Relationship of Family Function and cellular Immunity in Healthy Adult Males.
Young Mee Lee, Yoon Seen Choi, Soo Young Yoon, Kap No Lee, Hey Kyung Park, Myung Ho Hong
J Korean Acad Fam Med 1998;19(2):177-190.   Published online February 1, 1998
Background
: The immune system is controlled by a complex network of regulatory mechanisms which include neurologic and psychological factors. Previous studies of psychopathological population and population challenged by significant life events have shown that high levels of anxiety and depression are associated with impaired cellular immunity. However, less is known about the psychoimmunological relevance of family function with the immune function in healthy population. The aim of the present study was to investigate the presence and direction of relationship between family function and cellular immunity.

Methods : Design : Cross sectional, observational study. Participants : 41 healthy adult males from a family medicine ambulatory care unit in a tertiary hospital completed a series of psychometric instruments that include the Family APGAR(Adaptation, Partnership, Growth, Affection, and Resolve), FACES III. In parallel, lymphocyte subset assay, lymphocyte proliferative responses to the mitogen concanavalin(ConA), interleukin 1-beta, interleukin-2 was analysed to assess cell-mediated immune function.

Results : Family adaptability was inversely correlated with total T cell, B cell counts, helper T cell(T₄) and lymphocyte proliferative response to low dose mitogen Con A(p<0.05). Family cohesion was inversely correlated with suppressor T cell(T8)(p<0.05). In the lymphocyte proliferative response to low dose Con A stimulation, the extreme family showed the highest response compared to midrange and healthy family(p<0.05). Relative to moderately dysfucntional family, severe dysfucntional family and healthy family had significantly higher lymphocyte proliferative responses to the high dose Con A(p<0.05).

Conclusion : We suggest that family function could be related with immune function and it may impact on health and susceptibility to illness in healthy adult males. Further studies are required to elucidate the direction of relationship of family function and cellular immunity and the psychosocial mechanisms involved in the immune system.
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