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Original Article

The effect of hyaluronic acid injection compared to corticosteroids injection in hand osteoarthritis: a systematic review and meta-analysis of randomized control trials
Saran Malisorn, Non Sowanna, Kansak Boonpattharatthiti, Teerapon Dhippayom
Received May 9, 2025  Accepted July 20, 2025  Published online September 18, 2025  
DOI: https://doi.org/10.4082/kjfm.25.0125    [Epub ahead of print]
Background
Treatment of hand osteoarthritis (OA) often includes corticosteroid and hyaluronic acid (HA) injections. Some studies have reported better pain relief and improved function, whereas others have reported minimal long-term benefits. This study aimed to evaluate the effects of corticosteroids and HA injections on the management of hand OA.
Methods
PubMed, Embase, CENTRAL, and EBSCO Open Disk were searched from their inception to May 2024. Randomized controlled trials (RCTs) comparing intra-articular corticosteroid and HA injections in adults with hand OA were included. Data on demographics, interventions, and outcomes were extracted and the risk of bias was assessed using the Cochrane Risk of Bias 2. We performed a pairwise meta-analysis using a random-effects model to estimate the pooled effects of the included trials, that is, standardized mean differences (SMDs) with their corresponding 95% confidence intervals (CIs).
Results
Of 189 articles, three RCTs involving 180 participants (mean age, 62–62.9 years) were included. One RCT was identified through a database search, and two RCTs were identified through other searching techniques. The risk of bias was considered low in two trials and high in one trial. No significant difference in pain relief was found between the corticosteroid and HA treatments (SMD, 0.06; 95% CI, –0.23 to 0.35; I2=0.0%).
Conclusion
Corticosteroid and HA injections offered similar pain relief in patients with hand OA. Further long-term studies are necessary to evaluate the functional outcomes and potential side effects. However, this conclusion should be interpreted with caution due to the small sample size of the studies (PROSPERO registration number: CRD42024511411).
  • 2,093 View
  • 72 Download

Review Article

Elderly Abuse and Neglect on Population Health: Literature Review and Interventions from Selected Countries
Ahmad Nabeil Alias, Khalid Mokti, Mohd Yusof Ibrahim, Sahipudin Saupin, Mohd Faizal Madrim
Korean J Fam Med 2023;44(6):311-318.   Published online August 29, 2023
DOI: https://doi.org/10.4082/kjfm.23.0046
Elderly abuse and neglect are among the primary public health problems linked to global demographic changes in the population, impacting not only the well-being of the elderly but also the growth of the nation or economy. This article discusses the effects of elder abuse and neglect on population health from the national and international perspectives through a narrative review of previously published articles on the concept of aging, the prevalence of elderly abuse and neglect, its risk factors and effects, and finally measures, legal perspectives, and recommendations to curb it. Interventions in Malaysia and selected nations, including Indonesia, South Korea, the United States, Australia, and Hong Kong, are examined. This issue is important as the majority of countries are moving toward being elderly populations. Improving global surveillance and the monitoring of instances is essential to inform policy actions to prevent elder abuse. In addition, a thorough assessment of the identified risk factors for violence and steps to prevent violence is required.

Citations

Citations to this article as recorded by  
  • Prevalence of elder abuse and its correlated factors in Iranian community-dowelling older adults: a cross-sectional study
    Mohadese Maleki, Seyedeh Ameneh Motalebi, Mehdi Ranjbaran, Seyedehzahra Hosseinigolafshani
    BMC Geriatrics.2025;[Epub]     CrossRef
  • PTSD in Elder Abuse Survivors: Trauma Symptom Presentation and Treatment Outcomes With the PROTECT Intervention
    Clare Culver, Emily Carter, Olivia Fiallo, Nancy Wang, Talya Waxenberg, Samprit Banerjee, Isabel Rollandi, Jo Anne Sirey
    The American Journal of Geriatric Psychiatry.2025; 33(11): 1119.     CrossRef
  • Prioritizing care and addressing distinct needs of older adults with disabilities in Ghana amidst challenges
    Evans Appiah Osei, Felicia Addasah, Jenifer Oware, Mary Ani-Amponsah, Agnes Acquah, Edward Obeng Amoah, Cindy Afoakwa-Acheampong, Emmanuel Opoku-Adjei
    Geriatric Nursing.2025; 65: 103524.     CrossRef
  • When Age Meets Atrocity: Medical Realities for Israel’s Older Hostages
    John Adekoya
    Rambam Maimonides Medical Journal.2025; 16(4): e0024.     CrossRef
  • 8,584 View
  • 175 Download
  • 4 Web of Science
  • 4 Crossref

Original Article

Analysis of the Time Interval between the Physician Order for Life-Sustaining Treatment Completion and Death
Sung Yoon Joung, Chung-woo Lee, Youn Seon Choi, Seon Mee Kim, Seok Won Park, Eun Shik Mo, Jae Hyun Park, Jean Shin, Hyun Jin Lee, Hong Seok Park
Korean J Fam Med 2020;41(6):392-397.   Published online May 20, 2020
DOI: https://doi.org/10.4082/kjfm.19.0077
Background
This study aimed to explore the time interval distribution pattern between the Physicians Order for Life-Sustaining Treatment (POLST) form completion and death at a tertiary hospital in South Korea. It also examined the association between various independent parameters and POLST form completion timing.
Methods
A total of 150 critically ill patients admitted to Korea University Guro Hospital between June 1, 2018 and December 31, 2018 who completed the POLST form were retrospectively analyzed and included in this study. Data were analyzed with descriptive statistics, and group comparisons were performed using the chi-square test for categorical variables. Fisher’s exact test was also used to compare cancer versus non-cancer groups.
Results
More than half the decedents (54.7%) completed their POLST within 15 days of death and 73.4% within 30 days. The non-cancer group had the highest percentage of patients (77.8%) who died within 15 days of POLST form completion while the colorectal (39.1%) and other cancer (37.5%) groups had the lowest (P=0.336).
Conclusion
Our findings demonstrated a current need for more explicit guidance to assist physicians with initiating more timely, proactive end-of-life discussions.

Citations

Citations to this article as recorded by  
  • An Integrative Review of the State of POLST Science: What Do We Know and Where Do We Go?
    Elizabeth E. Umberfield, Matthew C. Fields, Rachel Lenko, Teryn P. Morgan, Elissa Schuler Adair, Erik K. Fromme, Hillary D. Lum, Alvin H. Moss, Neil S. Wenger, Rebecca L. Sudore, Susan E. Hickman
    Journal of the American Medical Directors Association.2024; 25(4): 557.     CrossRef
  • Discussing POLST-facilitated hospice care enrollment in patients with terminal cancer
    Ho Jung An, Hyun Jeong Jeon, Sang Hoon Chun, Hyun Ae Jung, Hee Kyung Ahn, Kyung Hee Lee, Min-ho Kim, Ju Hee Kim, Jaekyung Cheon, Su-Jin Koh
    Supportive Care in Cancer.2022; 30(9): 7431.     CrossRef
  • The Medical Orders for Scope of Treatment (MOST) form completion: a retrospective study
    Anastasia A. Mallidou, Coby Tschanz, Elisabeth Antifeau, Kyoung Young Lee, Jenipher Kayuni Mtambo, Holly Heckl
    BMC Health Services Research.2022;[Epub]     CrossRef
  • 5,922 View
  • 90 Download
  • 2 Web of Science
  • 3 Crossref

Review Article

Chronic Constipation in the Elderly Patient: Updates in Evaluation and Management
Amir Mari, Mahmud Mahamid, Hana Amara, Fadi Abu Baker, Afif Yaccob
Korean J Fam Med 2020;41(3):139-145.   Published online February 17, 2020
DOI: https://doi.org/10.4082/kjfm.18.0182
Chronic constipation (CC) is a common disorder in the elderly population globally and is associated with comorbidities and negative implications on the quality of life. Constipation prevalence varies in different studies, primarily owing to the nonuniformity of the diagnostic criteria. However, 15%–30% of individuals aged >60 years are diagnosed with CC. Primary care physicians are the main healthcare providers that manage constipation in elderly patients in parallel with increased population aging and increased prevalence of constipation. Physical inactivity, polypharmacy, chronic medical conditions, rectal hyposensitivity, and defecatory disorders all play a role in the pathogenesis of CC in elderly patients. Detailed anamnesis, particularly history related to chronic medication use, with digital rectal examination may assist in identifying constipation causes. Additionally, blood tests and colonoscopy may identify organic causes of CC. Physiologic tests (i.e., anorectal manometry, colonic transit time with radiopaque markers, and defecography) can evaluate the physiologic function of the colon, rectum, and anus. However, generally, there are several causes of constipation in older patients, and an individualized approach is recommended. Treatment of chronic idiopathic constipation is empiric, based on the stepwise approach. Lifestyle advice, adjustment of chronic medications, and prescription of laxatives are the first steps of management. Several laxatives are available, and the treatment is evolving in the last decade. Biofeedback is an effective therapy especially for defecatory disorders. This review aimed to summarize the most updated knowledge for primary care physicians in the approach and management of CC in elderly patients.

Citations

Citations to this article as recorded by  
  • Clinical Efficacy of Abdominal Massage Combined With Moxibustion for Treatment of Chronic Constipation in Elderly Patients
    Yanan Li, Xiaowei Li, Jingpeng Zang, Lili Hao, Yawei Gao, Ying Liao
    Neurogastroenterology & Motility.2026;[Epub]     CrossRef
  • Rehabilitation for Chronic Constipation: Integrative Approaches to Diagnosis and Treatment
    Luana Alexandrescu, Ionut Eduard Iordache, Alina Mihaela Stanigut, Laura Maria Condur, Doina Ecaterina Tofolean, Razvan Catalin Popescu, Andreea Nelson Twakor, Eugen Dumitru, Andrei Dumitru, Cristina Tocia, Alexandra Herlo, Ionut Tiberiu Tofolean
    Gastrointestinal Disorders.2025; 7(1): 11.     CrossRef
  • Life’s Simple 7 and its impact on chronic bowel disorders: a study on constipation and diarrhea in the U.S. adult population
    Hongzhi Sun, Lei Qi, Yiwei Ming, Weichen Wang, Maoneng Hu
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Attenuation of intestinal peristalsis with age is attributed to decreased sensitivity of receptors in the enteric nervous system
    Tsukasa Kobayashi, Yuko Takeba, Masanori Ootaki, Yuki Ohta, Keisuke Kida, Taroh Iiri, Naoki Matsumoto
    Cell and Tissue Research.2025; 400(3): 303.     CrossRef
  • Health multidimensional evaluation of institutionalized older adults according to cognitive performance
    Beatriz Cintra Martins, Lilian Barbosa Ramos, Anna Karla Carneiro Roriz, Henrique Salmazo da Silva
    Dementia & Neuropsychologia.2025;[Epub]     CrossRef
  • Advancements in the application of botulinum toxin type a in the treatment of anorectal disorders
    Xiaojuan Chen
    Toxicon.2025; 260: 108346.     CrossRef
  • Probiotics and prebiotics in the treatment of functional constipation in the elderly individuals
    Li Xu, Jian-Tang Guo, Jing Zhao, Ming-He Liu, Chen Mo
    World Journal of Gastrointestinal Pharmacology and Therapeutics.2025;[Epub]     CrossRef
  • Evaluation of nutritional and functional characteristics of noodles formulated with chickpea flour and moringa leaf powder
    Tanjum Kabir Khuku, Sanaullah Mazumdar, Borhan Uddin, Md. Syduzzaman
    Applied Food Research.2025; 5(1): 101062.     CrossRef
  • The role of constipation in the development of dyslipidemia in the elderly
    A. V. Martynenko, S. P. Nunes
    Fundamental and Clinical Medicine.2025; 10(2): 118.     CrossRef
  • Nutrition Focused Physical Examination Components Specific to Older Adults: A Modified Delphi Study
    Christina E. Gassmann, Caroline M. Kiss, Alainn Bailey, Laura Byham‐Gray, Diane L. Rigassio Radler
    Journal of Human Nutrition and Dietetics.2025;[Epub]     CrossRef
  • The impact of ageing on the structural compositions of the mucosa of human colon
    Nicholas Baidoo, Enrica De Rasis, Dion Tahiri, Gareth J. Sanger
    Tissue and Cell.2025; 97: 103090.     CrossRef
  • Prebiotics improve motor function, cognition and gut health in a preclinical model of Huntington’s disease
    Millicent N. Ekwudo, Bethany Masson, Madeleine R. Di Natale, Pamudika Kiridena, Nicholas van de Garde, Enie Lei, Sujan Kumar Sarkar, Vinod K. Narayana, Thibault Renoir, John B. Furness, Carolina Gubert, Anthony J. Hannan
    Brain, Behavior, and Immunity.2025; 130: 106074.     CrossRef
  • Fecal Impaction: An Unusual Cause of Acute Kidney Injury in a Kidney Transplant Recipient
    Hafsa Tariq, Madhuri Ramakrishnan, Pablo Portocarrero, Mallika Gupta, Nicholas Herrera, Jeffrey Klein, Aditi Gupta, Diane Cibrik, Richa Sharma
    Case Reports in Transplantation.2025;[Epub]     CrossRef
  • Inflammatory and morphological changes in the colon reflect early aging induced by d-galactose in rats
    Cherry Azaria, Bilqis Zahra Nabila, Yustina Andwi Ari Sumiwi, Rina Susilowati, Dewajani Purnomosari
    Scientific Reports.2025;[Epub]     CrossRef
  • The Association Between Malnutrition and Constipation in Elderly Individuals: A Cross-Sectional Analysis
    Nilüfer Acar Tek, Hatice Baygut, Mehmet Mustafa Tilekli
    Uluborlu Mesleki Bilimler Dergisi.2025; 8(3): 10.     CrossRef
  • Evaluating Korean Medicine Interventions for Elderly Constipation: A Scoping Review
    Jiye Kim, Seong-woo Lim
    The Journal of Internal Korean Medicine.2025; 46(6): 1409.     CrossRef
  • A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients
    Cezary Chojnacki, Marta Mędrek-Socha, Aleksandra Błońska, Janusz Błasiak, Tomasz Popławski, Jan Chojnacki, Anita Gąsiorowska
    Nutrients.2024; 16(7): 1027.     CrossRef
  • Predictors of inadequate bowel preparation in older patients undergoing colonoscopy: A systematic review and meta-analysis
    Yuanyuan Zhang, Lining Wang, Wenbi Wu, Shi Zhang, Min Zhang, Wenjing She, Qianqian Cheng, Nana Chen, Pengxia Fan, Yuxin Du, Haiyan Song, Xianyu Hu, Jiajie Zhang, Caiyan Ding
    International Journal of Nursing Studies.2024; 149: 104631.     CrossRef
  • Laxatives in Geriatric Practice: From Preoperative Bowel Preparation to Correction of Chronic Constipation
    V. S. Ostapenko
    Russian Journal of Geriatric Medicine.2024; 16(4): 289.     CrossRef
  • Development and validation of a nomogram to predict the risk of constipation after lumbar interbody fusion surgery
    Mingxin Chen, Si Cheng, Dian Zhong, Tao Hu, Xin Wang, Zhongliang Deng, Qingshuai Yu, Zhengjian Yan
    Archives of Orthopaedic and Trauma Surgery.2024; 144(5): 1907.     CrossRef
  • A survey on functional constipation and its risk factors in older people in Shahreza, Iran
    Mina Amiri, Akbar Hassanzadeh, Majid Rahimi
    Journal of Education and Health Promotion.2024;[Epub]     CrossRef
  • Efficacy and mechanism of acupuncture for functional constipation in older adults: study protocol for a randomized controlled trial
    Yisheng Huai, Qian Fan, Yiyue Dong, Xu Li, Junwei Hu, Lumin Liu, Yuelai Chen, Ping Yin
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • An abdominal vibration combined with walking exercise (AVCWE) program for older patients with constipation: Development and feasibility study
    Yuan-Yuan Zhang, Ramoo Vimala, Ping Lei Chui, Ida Normiha Hilmi
    Saudi Journal of Gastroenterology.2024; 30(3): 173.     CrossRef
  • Chronic constipation: current options of pathogenetic therapy
    M. D. Ardatskaya, L. I. Butorova, A. A. Anuchkin, I. N. Gaivoronsky, A. I. Pavlov, O. Yu. Patsenko
    Meditsinskiy sovet = Medical Council.2024; (8): 145.     CrossRef
  • Insights into the current state of knowledge, practice, and attitudes of physicians regarding gastrointestinal motility disorders in Egypt
    Enaam Ali Al Mowafy, Marwa M. AboKresha, Sally Waheed Elkhadry, Mohamed Bassam Hashem, Ahmed Elganzory, Sayed Ahmed Sayed, Mohammad Almohamady Khaskia
    BMC Gastroenterology.2024;[Epub]     CrossRef
  • Case Report: Toxic megacolon secondary to chronic constipation and cocaine consumption
    Bertha Dimas, Guillermo Hernández, Ivonne Peralta, Ansony Godinez, Gabriela Gutierrez, Fernando Cruz
    Frontiers in Surgery.2024;[Epub]     CrossRef
  • Efficacy of Whole System Approach Ayurveda Interventions in Vibhanda W. S. R. Old Age Constipation – A Randomized Control Clinical Trial
    Ramesh Shivappa Killedar, Savita Angadi, Uma Shetti, Meghana Patil, Pradeep S. Shindhe, Sheetal Kumar Bolaj
    Journal of Ayurveda.2024; 18(3): 181.     CrossRef
  • The problem of constipation in the practice of an outpatient doctor
    I. G. Pakhomova, A. A. Lelyakova
    Meditsinskiy sovet = Medical Council.2024; (15): 158.     CrossRef
  • Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly
    Itsuro Kazama
    Kidney Research and Clinical Practice.2024; 43(6): 703.     CrossRef
  • DESIGN, DEVELOPMENT AND EVALUATION OF HERBAL LOZENGES FOR LAXATIVE ACTIVITY
    Ravali K. Battula, Aswani Borrigorla, Sivani Macha, Maddhu L. Palisetty, Sri M. Motupalli, Ravi Ketipally, Ramarao Nadendla
    INDIAN DRUGS.2024; 61(12): 43.     CrossRef
  • Global prevalence of constipation in older adults: a systematic review and meta-analysis
    Nader Salari, Mohammadrasool Ghasemianrad, Mojtaba Ammari-Allahyari, Shabnam Rasoulpoor, Shamarina Shohaimi, Masoud Mohammadi
    Wiener klinische Wochenschrift.2023; 135(15-16): 389.     CrossRef
  • Yaşlılarda Geriatrik Sendromlardan Biri Olan Kırılganlık ve Hemşirelik Bakımı
    Servet Kalyoncuo
    Black Sea Journal of Health Science.2023; 6(3): 520.     CrossRef
  • Prevalence, Symptoms, and Associated Factors of Chronic Constipation Among Older Adults in North-East of Peninsular Malaysia
    Patimah Abdul Wahab, Dariah Mohd Yusoff, Azidah Abdul Kadir, Siti Hawa Ali, Lee Yeong Yeh
    Clinical Nursing Research.2022; 31(2): 348.     CrossRef
  • The Intestinal Barrier Dysfunction as Driving Factor of Inflammaging
    Eva Untersmayr, Annette Brandt, Larissa Koidl, Ina Bergheim
    Nutrients.2022; 14(5): 949.     CrossRef
  • Prevalence of constipation and use of laxatives, and association with risk factors among older patients during hospitalization: a cross sectional study
    Hanne Konradsen, Veronica Lundberg, Jan Florin, Anne-Marie Boström
    BMC Gastroenterology.2022;[Epub]     CrossRef
  • Effect of Fresh Dendrobe Juice Consumption on Senile Habitual Constipation for Older People: A Four-Week Randomized Controlled Trial
    Yuchao Le, Shihua Cao, Mengxin Wang, Danni He, Yanfei Chen, Beiying Qian
    Sustainability.2022; 14(6): 3656.     CrossRef
  • Effects of Lactobacillus plantarum P9 Probiotics on Defecation and Quality of Life of Individuals with Chronic Constipation: Protocol for a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    Wenjun Liu, Nong-Hua Lu, Xu Zhou, Yingmeng Li, Yong Xie, Longjin Zheng, Weifeng Zhu, Qiuping Xiao, Ni Yang, Kexuan Zuo, Qingni Wu, Tielong Xu, Heping Zhang, Mohammad Hashem Hashempur
    Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1.     CrossRef
  • The effect of Cassia fistula L. syrup in geriatrics constipation in comparison with the lactulose: A randomized clinical trial
    Farangiz Sepehr, Hoda Shirafkan, Catherine Behzad, Zahra Memariani, Seyyed Ali Mozaffarpur
    Journal of Ethnopharmacology.2022; 297: 115466.     CrossRef
  • Perioperative management of elderly and senile patients. Recommendations
    Igor B. Zabolotskikh, E. S. Gorobets, E. V. Grigoryev, Yu. V. Kotovskaya, K. M. Lebedinskii, T. S. Musaeva, E. A. Mkhitaryan, A. M. Ovechkin, V. S. Ostapenko, A. V. Rozanov, N. K. Runikhina, O. N. Tkacheva, N. V. Trembach, V. E. Khoronenko, M. A. Cherdak
    Annals of Critical Care.2022; (3): 7.     CrossRef
  • Diagnostics of Gastrointestinal Motility and Function: Update for Clinicians
    Amir Mari
    Diagnostics.2022; 12(11): 2698.     CrossRef
  • The mechanism of intestinal flora dysregulation mediated by intestinal bacterial biofilm to induce constipation
    Ruibiao Fu, Zhongpeng Li, Rui Zhou, Chaoyang Li, Shuai Shao, Jin Li
    Bioengineered.2021; 12(1): 6484.     CrossRef
  • Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus
    V. T. Ivashkin, M. G. Mnatsakanyan, V. S. Ostapenko, А. P. Pogromov, V. M. Nekoval, E. A. Poluectova, Yu. V. Kotovskaya, N. K. Runikhina, N. V. Sharashkina, P. V. Tsarkov, N. O. Tkacheva, Yu. N. Belenkov
    Russian Journal of Gastroenterology, Hepatology, Coloproctology.2021; 31(4): 7.     CrossRef
  • Management of Opioid-Induced and Non–Opioid-Related Constipation in Patients With Cancer: Systematic Review and Meta-Analysis
    Pamela Ginex, Brian Hanson, Kristine LeFebvre, Yufen Lin, Kerri Moriarty, Christine Maloney, Mark Vrabel, Rebecca Morgan
    Oncology Nursing Forum.2020; 47(6): E211.     CrossRef
  • 31,581 View
  • 544 Download
  • 31 Web of Science
  • 43 Crossref

Case Report

Epileptic Seizure Due to Disulfiram Treatment
Habib Erensoy, Ahmet Emre Sargin
Korean J Fam Med 2019;40(6):406-408.   Published online January 7, 2019
DOI: https://doi.org/10.4082/kjfm.18.0014
Disulfiram has been used for the treatment of alcohol dependence for nearly 65 years and is approved by the Food and Drug Administration. It causes negative reinforcement by accumulating toxic acetaldehyde due to irreversible inhibition of aldehyde dehydrogenase. Disulfiram has very few side effects when taken without alcohol. Epileptic seizure induction is a rare side effect in therapeutic doses, and its mechanism is unknown. We present a patient with a single epileptic seizure which was thought to be due to disulfiram used in the treatment of alcohol dependence. We did not find it ethical to administer disulfiram again because the patient discontinued alcohol use and was afraid of epileptic seizures.

Citations

Citations to this article as recorded by  
  • Disulfiram-Associated Generalized Tonic–Clonic Seizures
    Sivapriya Vaidyanathan, Sudharshan Raghunathan, Suma T. Udupa, Ravindra Neelakanthappa Munoli, Malkonahalli Srikanta Manjushree, Samir Kumar Praharaj
    American Journal of Therapeutics.2024; 31(4): e422.     CrossRef
  • Anticancer Effects of New Disulfiram Analogs
    Omeima Abdullah, Christopher A. Beaudoin, Ziad Omran
    Biological and Pharmaceutical Bulletin.2024; 47(11): 1804.     CrossRef
  • Disulfiram-induced epileptic seizures
    Violeta Nogueira, Mafalda Azevedo Mendes, Inês Pereira, Joana Teixeira
    BMJ Case Reports.2021; 14(3): e236296.     CrossRef
  • 10,496 View
  • 190 Download
  • 3 Web of Science
  • 3 Crossref

Original Articles

The Effect of Having a Regular Doctor as a Primary Care Provider on Emergency Room Utilization in South Korea
Su-Young Lee, Hyeong-Seok Lim
Korean J Fam Med 2017;38(6):322-326.   Published online November 14, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.6.322
Background

Because primary care is the cornerstone of an effective health care system, many developed countries have striven to establish and strengthen their primary care systems. However, the primary care system in South Korea is not well established, and primary care research is still in its infancy. This study aimed to show the benefits of regular doctors as primary care providers in South Korea by analyzing the effect of regular doctor visits on emergency room (ER) visits.

Methods

We analyzed cross-sectional data on 11,293 adults aged 18 years and over collected from the 2013 Korea Health Panel Survey (beta version 1.0). We classified those participants with and without regular doctors into the treatment and control groups, respectively, and estimated the average treatment effect (ATE) of having a regular doctor on ER visits. We used counterfactual framework and propensity score analysis to adjust for unevenly distributed confounding covariates between treatments and control groups.

Results

The estimated conditional ATE of a regular doctor on ER visits was statistically insignificant in the general population (-0.4%; 95% confidence interval [CI], -2.0 to 1.2) and in the subgroup of patients with hypertension (-1.8%; 95% CI, -4.5 to 0.9). However, in patients with diabetes mellitus (DM), the estimated ATE was statistically significant (-5.0; 95% CI, -9.2 to -0.7).

Conclusion

In the total study population, having a regular doctor did not result in a significant difference in ER visits. However, there was a decrease in ER visits in patients with DM in South Korea.

Citations

Citations to this article as recorded by  
  • Demographic Disparities and Factors Influencing Cancer Treatment Decision-Making
    Safa Elkefi, Avishek Choudhury
    Journal of Cancer Education.2025; 40(5): 752.     CrossRef
  • Prevalence and Associated Factors of Having a Family Physician or Regular Doctor among Community-Dwelling Adults in South Korea: A Cross-Sectional Study
    Yookyeong Sim, Su-Min Jeong, Hee-Kyung Joh
    Korean Journal of Family Practice.2024; 14(1): 40.     CrossRef
  • The impact of primary health care reform on hospital emergency department overcrowding: Evidence from the Portuguese reform
    Alvaro Almeida, Joana Vales
    The International Journal of Health Planning and Management.2020; 35(1): 368.     CrossRef
  • 6,143 View
  • 40 Download
  • 2 Web of Science
  • 3 Crossref
Background

Homelessness is associated with an increased risk of exposure to Mycobacterium tuberculosis. Several factors, including alcoholism, malnutrition, lack of stable housing, combine to make tuberculosis more prevalent in the homeless. The aims of this study were to determine the factors associated with increasing success rate of tuberculosis treatment in the homeless.

Methods

A cross-sectional analysis of the clinical features in 142 pulmonary tuberculosis-positive homeless patients admitted to the Busan Medical Center from January 2001 to December 2010 was carried out. These results were compared with a successful treatment group and incomplete treatment group. We also evaluated the risk factors of treatment non-completion. Statistical analysis for the comparisons was performed using a χ2 test, independent samples t-test, and multiple logistic regression.

Results

Comparison of clinical characteristics showed significant differences between the two groups in the type of residence (P < 0.001), diseases with risk factors (P = 0.003), and history of tuberculosis treatment (P = 0.009). Multiple regression analysis revealed the residence (odds ratio [OR], 4.77; 95% confidence interval [CI], 2.05 to 11.10; P < 0.001) and comorbidity with risk factor (OR, 2.72; 95% CI, 1.13 to 6.53; P = 0.025) to be independently associated with treatment success.

Conclusion

To improve the success rate of tuberculosis treatment in the homeless person, anti tuberculosis medication should be taken until the end of treatment and a management system for the homeless person is required. Further social and medical concerns for stable housing and management of comorbidity may lead to an improvement in the successful tuberculosis treatment of homeless person.

Citations

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  • Prevalence of pulmonary tuberculosis and its associated factors among people who ecprience homelessness living in selected towns in Wolaita zone, southern Ethiopia
    Sisaynesh Kenu, Takele Teklu, Fithamlak Solomon Bisetegn, Getachew Alemu
    Journal of Health, Population and Nutrition.2025;[Epub]     CrossRef
  • Prevalence of Smear-Positive, Rifampicin-Resistant Mycobacterium tuberculosis and Related Factors Among Residents with Cough in Northern Ethiopian Refugee Health Facilities
    Hailemariam Mezgebe, Teklay Gebrecherkos, Dawit Hagos, Saravanan Muthupandian
    Infection and Drug Resistance.2024; Volume 17: 1135.     CrossRef
  • Prevalence and Characteristics of Tuberculosis in the Korean Homeless Population Based on Nationwide Tuberculosis Screening
    Heesang Han, Ji-Hee Lee, Sung Jun Chung, Beong Ki Kim, Yedham Kang, Hangseok Choi, Hee-Jin Kim, Seung Heon Lee
    Tuberculosis and Respiratory Diseases.2024; 87(4): 514.     CrossRef
  • Impact of Active Surveillance for Carbapenem-resistant Enterobacterales in a Homeless Patient Ward
    Dong Hoon Shin, Jeong Eun Yoon, Inhyang Eom, Namhee Kim, Mi Seon Han, Sang Won Park, Eunyoung Lee
    Korean Journal of Healthcare-Associated Infection Control and Prevention.2024; 29(2): 128.     CrossRef
  • Inadequate housing and pulmonary tuberculosis: a systematic review
    Ju-Yeun Lee, Namhee Kwon, Ga-yeon Goo, Sung-il Cho
    BMC Public Health.2022;[Epub]     CrossRef
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    Paula Hino, Thais Tiemi Yamamoto, Shyrlaine Honda Bastos, Aline Ale Beraldo, Tânia Maria Ribeiro Monteiro de Figueiredo, Maria Rita Bertolozzi
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  • 5,264 View
  • 26 Download
  • 7 Crossref

Review

Urinary Incontinence in Women.
Jong Bo Choi
Korean J Fam Med 2010;31(9):661-671.   Published online September 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.9.661
The International Continence Society (ICS) defines urinary incontinence (UI) as the complaint of any involuntary leakage of urine. The common pathophysiology of UI in women involves an overactive detrusor or an incompetent urethral sphincter. Therefore UI is categorized as stress urinary incontinence (SUI), urge urinary incontinence (UUI), mixed urinary incontinence (MUI) and overflow incontinence. SUI and UUI are the two most common types of UI in women. According to Korean national survey in 2005, the prevalence of UI is 24.4% and the prevalence of UI increased with age. Of those women, 48.8% reported SUI, 7.7% UUI, 41.6% mixed UI. Therefore the proper diagnostic work-up is needed to increase clinical outcome because many treatment options are being in women with UI. Non-invasive treatments include behavioral therapy, pharmacotherapy. Especially anticholinergics are the cornerstone of UUI treatment, whereas surgical treatments, such as TOT, TVT, are considered as a gold standard of SUI treatment. The cure rate of TOT or TVT surgery for SUI revealed 80-90% according to many studies and complication rate is reported about 5%. Therefore, by effectively identifying and treating incontinence it is possible to significantly improve patients' quality of life.

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    Se Bin Kim, Da Hye Gam, Ji Woo Hong, Jin Woo Kim
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  • Study on the Awareness and Demands of Korean University Students Majoring in Physical Therapy: Focus on Women’s Health Physical Therapy
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    Journal of The Korean Society of Physical Medicine.2021; 16(2): 31.     CrossRef
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    Hyun-seo Nam, Tae-hyun Baek
    The Journal of Internal Korean Medicine.2021; 42(3): 293.     CrossRef
  • Association between urinary incontinence and bone health in Korean elderly women based on data from the Korea National Health and Nutrition Examination Survey
    Ji Hyun Moon, Yun Hwan Oh, Mi Hee Kong, Jung Sik Huh, Hyeon Ju Kim
    Electronic Journal of General Medicine.2019; 16(3): em140.     CrossRef
  • Association between Muscle Loss and Urinary Incontinence in Elderly Korean Women
    Hyun-Jung Park, Se-Ryung Choo, Sang-Hyuk Kim, Hyun-Ki Lee, Ki Young Son
    Korean Journal of Family Medicine.2015; 36(1): 22.     CrossRef
  • Randomized Controlled Trial for Salvia sclarea or Lavandula angustifolia: Differential Effects on Blood Pressure in Female Patients with Urinary Incontinence Undergoing Urodynamic Examination
    Geun Hee Seol, Yun Hee Lee, Purum Kang, Ji Hye You, Mira Park, Sun Seek Min
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  • Effect of Kegel Exercise to Prevent Urinary and Fecal Incontinence in Antenatal and Postnatal Women: Systematic Review
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  • 4,181 View
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  • 8 Crossref

Original Article

A Preliminary Study for the Effect of Multidivisional Program for Social Skill Improvement on Senile Dementia.
Kwan Hong Ko, Hwan Sik Hwang, Hoon Ki Park, Hee Jung Chae, Jeong Hyun You
Korean J Fam Med 2010;31(3):182-189.   Published online March 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.3.182
Background
Aging population correspond with an increase in the numbers of dementia patients. Dementia decreases the quality of life of patients and care-givers. However, current pharmacological treatment is limited by modest efficacy and adverse effect. Nonpharmacological treatment for dementia has been considered to be a substitute treatment. Recently we developed a special planned program for dementia with depression. The aim of this study was to evaluate therapeutic effect of this program. Methods: We included patients aged 65 and older who diagnosed dementia with depression in a geriatric institution from April to June, 2006. We surveyed their sex, age, education period, and histories of hypertension, smoking, and alcohol intake. Patients in experimental group carried out our program, including cooking, painting, recreation, and activity, 9 times for 60 minutes a session. All included patients were checked Korean Mini-Mental State Examination (K-MMSE) and Korean Form of Geriatric Depression Scale (KGDS) before starting program and after 3 months when programs finished. Results: There was no difference in demographic factors between two groups. K-MMSE was significantly improved in experimental group compared with control group (P = 0.01). And, the KGDS was significantly improved in experimental group compared with control group (P = 0.00). Conclusion: Multidivisional program for social skill improvement was effective on treatment for patients of dementia with depression. Nonpharmacological treatment for dementia with depression would be developed and studied to enhance the qualities of life of patients and care of dementia.

Citations

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  • Evaluating the Efficacy of Therapeutic Programs on Improving Cognitive Function and Depression among Older Adults Living with Dementia in Korea
    Jaeeon Yoo, Sunhee Lee
    International Journal of Environmental Research and Public Health.2020; 17(9): 3218.     CrossRef
  • 2,769 View
  • 29 Download
  • 1 Crossref

Review

Diagnosis, and Treatment of Generalized Anxiety Disorder in Primary Practice.
Jeong Min Song, Jeong Ho Chae
J Korean Acad Fam Med 2005;26(9):517-528.   Published online September 10, 2005
Generalized anxiety disorder (GAD) is highly prevalent psychiatric disorder in primary care population and is a source of major morbidity. However, the underawareness and undertreatment of GAD, which is due to insufficient knowledge about the disorder, often hinder the proper management of this chronic condition. Other characteristic features such as chronic course of GAD, frequent comorbidity with other anxiety and depressive disorders, and the controversy regarding the best diagnostic criteria should be fully discussed. First of all, proper and accurate diagnosis is crucial for an appropriate management. Primary care management of GAD and associated comorbidities includes education about the nature of GAD and counseling about treatment alternatives and coping strategies is an important first step. The most effective treatment of GAD is combined psychotherapeutic and pharmacotherapeutic approach. The major psychotherapeutic approaches to GAD are cognitive-behavioral therapy with relaxation techniques. Pharmacological treatment for GAD includes benzodiazepine, buspirone, and antidepressants. In this review, these combined treatment at the view point of primary practitioners was described.
  • 1,667 View
  • 25 Download

Original Article

Clinical Characteristics, Diagnosis, Treatment, and Clinical Outcomes of TB Patients at a Private University Hospital in Korea.
Seong Hoon Choi, Woo Sung Sun, Mi Na Kim, Tae Sun Shim
J Korean Acad Fam Med 2005;26(8):481-489.   Published online August 10, 2005
Background
: Even though tuberculosis (TB) is still a major public concern in Korea, there are few data on the management of TB patients and its outcome in the private sector in contrast with those of the public sector.

Methods : The nine-hundred-twelve TB patients who were registered in a private university hospital from 2001 to 2002 were enrolled. The patients were divided into pulmonary (TBP), extrapulmonary (TBE), and combined (TBP+E) groups, and were also divided into initial and retreatment groups. The clinical characteristics, diagnostic methods, treatment regimens, and outcomes were analyzed and compared between the groups.

Results : The mean age of 912 patients was 49.2 years and the male-to-female ratio was 56%:44%. The number of patients of the initial and retreatment groups of TBP, and those of (TBE+TBP+E) were 449, 169, 237, 57, respectively. The bacteriological study was performed in 97.9%, and positive culture was confirmed in 54.5% and 29.6% of patients with TBP and (TBE+TBP+E), respectively (P<0.05). The AFB smear was positive in 40.8% of TBP patients. The PCR was done in 63.6% of (TBE+TBP+E) group. The MDR was detected in 7.6% of isolates. Overall, treatment completion rate was 74.6%, default rate 13.7%, and death rate 0.5%.

Conclusion : Even though the management of TB patients in a private hospital was satisfactory in terms of national guidelines, the high default rate was still a problem. Efforts to decrease the default rate is needed independently or in cooperation with the public sector.
  • 1,620 View
  • 52 Download

Review Article

The Clinical Approaches to Learning Disorder for Primary Physicians
Dong Ho Song, Young Min Lew
J Korean Acad Fam Med 2004;25(9):643-652.   Published online November 5, 2004
It is not uncommon for children and adolescents with learning disabilities to have neurologically based disorders and other associated psychosocial problems. Those children have learning disorder need systematic psychiatric and neuropsychological evaluations for proper managements. Moreover many educational test instruments and special educational literatures use an information processing model for understanding learning and learning disabilities. Any learning disorders can involve more than one area in various dysfunctional processes; input disabilities (visual and auditory perceptions, and other sensory integrations), integration disabilities (sequencing, abstraction, and organization), memory disabilities, and output disabilities (language and motor). Individuals with learning disability require appropriate interventions, whether they are clinical or educational. They must be screened primarily by family physicians, pediatricians, and psychiatrists, and have psychosocial supports for themselves and their family, and then be referred to child and adolescent psychiatrists for optimal treatment planning and multimodal managements.
  • 1,576 View
  • 46 Download

Review

Diagnosis and Treatment of Tic Disorders.
Boong Nyun Kim
J Korean Acad Fam Med 2004;25(5):359-370.   Published online May 10, 2004
Tics are brief, rapid and repetitive movement and sounds that are either simple or complex in presentation. Tics can be preceded by a premonitory urge (sensation) that decreases after tic is completed. The fourth edition of Diagnostic Statistical Manual of Mental Disorder (DSM- IV) includes diagnoses for Tourettes disorder, chronic motor or vocal tic disorder, transient tic disorder and tic disorder not otherwise specified (Table 1) according to the duration of tic symptoms and degree of complexity. The purposes of treatment of tic disorders must be set up based on the comprehensive evaluation of developmental profiles, strength, weakness, family situation, and school adaptation status. The family education must be included early in treatment process and psychosocial treatment including the cognitive behavioral therapy will be needed to develop and maintain the self-efficacy in controlling the tic symptoms. The most effective and efficient method for the reduction of tic symptoms, however, are drug treatment. The pharmacotherapy is usually one component of treatment for chronic tic disorder and Tourettes disorder. The gold standard for tic reduction is the dopaminergic receptor blocking agent (or antipsychotic agent, neuroleptics). The primary drugs are haloperidol, pimozide, and risperidone. Among theses, risperidone will be the primary choice because of its low side effect profiles, esp, neurologic side effects. In the near future, the studies on the efficacy of the olanzapine, quetiapine and ziprasidone will be more reported. As second line drugs, clionidine, guanfacine, nicotine related drugs can be considered.
  • 2,002 View
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Original Article

Desired Weight of Obesity Patients.
Hyun Ah Park, Eun Ju Sung, Yong Woo Park, Sang Woo Oh, Hye Soon Park
J Korean Acad Fam Med 2003;24(10):904-911.   Published online October 10, 2003
Background
: Although expert panels and guidelines recommend that 5∼10% weight reductions of initial body weight have beneficial effects for decreasing obesity-related complications, obese persons tend to desire greater weight losses. Little is known about the patients' expectations and the disparity of goal weight between physicians and patients. The aim of this study was to evaluate the patients' weight loss expectation, and the association between the degree of desired weight losses and treatment outcomes.

Methods : A total of 283 obese subjects (84 men, 199 women), aged ≥20 years with body mass index (BMI) over 25 kg/m2 from 19 obesity clinics were included. Patients' desired weight as evaluated using modified GRWQ (Goals and Relative Weight Questionnaire) which included goal weight, ideal weight, satisfactory weight, acceptable weight, and disappointed weight. After 12 weeks, subsequent weight changes and treatment adherence were investigated.

Results : Mean BMI of men and women were 30.9±4.2 kg/m2 and 29.1±3.8 kg/m2, respectively. Men expected 13.2 kg (14.0%) mean weight reductions and women expected 10.8 kg (15.7%) mean reductions during the 3 months. The heavier the patient's weight, the greater the reduction amount was desired in both men and women. During the 3 months, the dropout rates of men and women were 40.1% and 46.2%, respectively. In women, the amount of desired weight reduction as significantly higher in the dropout group compared to the non-dropout group. Those who attained pre-determined goal weight after 3 months were 6% for men and 4% for women. After 3 months, 81% of male subjects and 80% of female subjects had not achieved even their predefined disappointed weight.

Conclusion : Obese patients seeking treatment expected average of 15% weight reduction, greater than 'medically reasonable or successful' weight reductions. The disparities between patients' expectations and physicians' recommendations could influence treatment adherence.
  • 1,594 View
  • 10 Download

Review

Evaluation and Management of Chronic Pain.
Yoon Kyoo Kang
J Korean Acad Fam Med 2003;24(2):103-111.   Published online February 10, 2003
Chronic pain is a self-sustaining, self-reinforcing, and self- regenerating process. It persists beyond 3∼6 months regardless of initial diagnostic category. It is not a symptom of an underlying acute somatic injury but rather, a destructive illness in its own right. It is an illness of the whole person and not a disease caused by the pathological state of an organ system. Chronic pain is persistent, long-lived, and progressive. Pain perception is markedly enhanced. Pain related behaviour becomes maladaptive and grossly disproportional to any underlying noxious stimulus, which usually has healed and no longer serves as an underlying pain generator. The purpose of this paper to present an approach to the prevention of chronic pain and disability, and to provide the clinician with potentially useful tools for the recognition of individuals at risk for chronic illness for whom multidisciplinary treatment is indicated.
  • 2,003 View
  • 40 Download

Original Article

The Factors Associated with Change in Percent Obesity after Obesity Treatment among Obese Children and Adolescents.
Ka Young Lee, Jin Kyung Kim, Nam Su Lee, Jeong Hee Han, Tae Jin Park, Hye Nyeon Jeon
J Korean Acad Fam Med 2003;24(1):64-71.   Published online January 10, 2003
Background
: The purpose of this study was to find changes in percentage obesity and the factors associated with the changes after its treatment in obese children and adolescents.

Methods : A total of 42 obese children from 3- to 17- year-olds (males 60%) were enrolled in an obesity treatment program at least 3 times. They were provided with an individual weight control program that included dietary, activity, and behavioral change information. The paired t-test, Kruskal-Wallis test, Mann-Whitney test, and linear regression were used for analyses.

Results : The means of BMI, percent body fat, and percent obesity were 27.4 kg/m2, 39.4%, and 52.3%, respectively. Among them, 85.3% of obese children had one or more abnormalities on biochemical tests and 32.4% of them had 3 or more abnormalities. There was a significant reduction in weight (1.4 kg), BMI (1.1 kg/m2), percent body fat (1.8%) and percent obesity (7.1%), whereas height increased significantly by 1.3 cm after the treatment. The decrease in percent obesity was associated significantly with the number of follow-up, the number of accompanied biochemical abnormality, and the duration of treatment. The decrease in percent obesity was 12.9% among obese children who were followed-up 6 times or more, by 12.2% among those who did not accompany biochemical abnormality and by 13.3% among those who were retained in the program for 76 days or over. However, the change in % obesity was not associated with sex, age groups (<12, ≥12-year-old), severity of obesity and parental obesity. The percent obesity decreased by 5.2% as the number of follow-up (n=3/4, 5/6∼17) increased after adjusting for sex, age groups and the number of biochemical abnormalities. The number of follow-up also explained 38% for the variance of change in percent obesity in that model.

Conclusion : Continuous program retention was an effective factor to reduce percent obesity. Therefore, further investigation is needed to develop methods to enforce program retention.
  • 1,679 View
  • 12 Download

Reviews

Clinical Importance and Application of Hyaluronic Acid.
Jeung Tak Suh
J Korean Acad Fam Med 2002;23(9):1071-1079.   Published online September 10, 2002
  • 1,617 View
  • 26 Download
Diagnosis and Treatment of HIV Infection.
Young Goo Song
J Korean Acad Fam Med 2002;23(8):988-998.   Published online August 10, 2002
  • 1,350 View
  • 12 Download
Original Articles
Improvement of insight in patients with alcohol dependence by treatmen programs.
Jong Sung Kim, Byoung Kang Park, In Sul Yu, Mi Kyeung Oh
J Korean Acad Fam Med 2000;21(9):1180-1187.   Published online September 1, 2000
Background
: The first step for the recovery of alcoholics is the formation of true insight which enables them to admit that they are alcoholic. This study was designed to analyze the changes in insight status by treatment programs.

Methods : The subjects were 214 alcohol dependents who participated in the insight-oriented treatment programs for at least 1 week. Their insight status were measured through HAIS before and after treatment.

Results : Of 214 sjbjects, 83(38.3%) were in poor-, 103 (48.1%) in fair-, and 28 (13.1%) in good-insight before treatment, and 56 (26.2%) in poor-, 97(45.3%) in fair-, and 61(28.5%) in good-insight after treatment. Mean HAIS scores of the subjects were 5.35 (SD=8.04) after treatment. The magnitude of insight-improvement was negatively correlated with the HAIS scores before treatment in poor-insight group and positively correlated with the duration of participation in treatment in fair-insight group.

Conclusion : We confirmed the fact that the insight status of patients could be improved by treatment. It was also suggested that the therapeutic strategy needed an individual approach according to the insight state of a patient.
  • 1,674 View
  • 29 Download
Development of an OPD-based childhood obesity control program and the effects of its utilization.
Hye Ree Lee, Yun Ju Kang, Jae Yong Shim
J Korean Acad Fam Med 1998;19(10):787-800.   Published online October 1, 1998
Background
: Although childhood obesity is an increasing public health problem in our society and a number of regimens have been developed and distributed for the treatment of adult obesity, few studies have focused on therapeutic programs for obese children. The objective of this study was to develop and measure the effects of an OPD-based childhood obesity control program.

Methods : The OPD-based childhood obesity control program was developed by reviewing the preexisting literature and consulting specialists. It was applied to the 4-6th grade obese(obesity index≥30%) children. The effects of intervention were assessed by the changes in obesity-related behavior, caloric and nutrient intake and exercise amount. The effects in the OPD-based group(group I) were also compared with the school-based group(group II)and the no intervention group(group III).

Results : The OPD-based program was developed based on behavioral modification principles such as self monitoring, stimulus control, positive reinforcement, social support, cognitive change and behavioral contracts and contained diet and exercise therapy. The developed program was applied to 34 pairs(child and mother) in the treatment group of which 21 pairs completed the basic sessions and 17 pairs completed the additional follow up session. Significant changes, decreases in obesity index were observed in the OPD-based group. No significant changes were found in the school-based group whereas increased degrees of obesity were found in the no intervention group. Obesity related behavior scores were significantly increased in both the OPD- and school-based groups. The children in both the OPD-based group showed significant decrease in dietary intake and increase in exercise amount.

Conclusion : Although it was a short-term treatment result, the OPD-based program was more effective than the school-based program in childhood obesity control. We suggest that a control program of comparable intensity and individualization as ours is required, for effective childhood obesity control.
  • 1,590 View
  • 13 Download
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