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Review Articles

Risk-Reducing Measures for Cancer Prevention
Israel Oluwasegun Ayenigbara
Korean J Fam Med 2023;44(2):76-86.   Published online March 20, 2023
DOI: https://doi.org/10.4082/kjfm.22.0167
Cancer, or malignancy, continues to be one of the most serious health problems in the world, leading to death and disability. Unlike in previous years, where new cases of cancer were predominant in developed nations, the number of cases of cancer and the resultant deaths are increasing in low- and middle-income countries. This is partially attributable to the current trend of adopting a Western lifestyle, substantial urbanization, and the rise in infections, such as the human papillomavirus (HPV) and hepatitis B virus (HBV), which together account for over 30% of cancer cases in underdeveloped and developing nations. The deleterious impact of cancer, as cases multiply worldwide, is multi-dimensional. Cancer exerts serious physical, psychological, and monetary burdens, not only on cancer patients but also on their family members, close friends, health care systems, and society at large. Importantly, over half of all cancer types can be prevented globally by mitigating the risk and causative factors as well as prompt adherence to scientifically recommended prevention measures. This review provides various scientifically based and people-centered strategies that every individual could adopt to reduce their risk of developing cancer in the future. It is recommended that, for these cancer prevention strategies to be effective, there should be a strong political will from the governments of individual countries to enact specific laws and implement policies that will significantly reduce sedentary lifestyles and unhealthy eating among the general public. Likewise, HPV and HBV vaccines, as well as cancer screenings, should be made available, affordable, and accessible on a timely basis for those who are eligible to take them. Finally, intensified campaigns and numerous informative and educational programs that promote cancer prevention should be initiated globally.

Citations

Citations to this article as recorded by  
  • Vegan Diet: A Novel Trend in Healthy Living
    Gaithaongamliu Kamei, Prasad Rasane, Jyoti Singh, Sawinder Kaur, Mahendra Gunjal, Jaspreet Kaur, Raghav Gupta, Dipendra Kumar Mahato, Sushma Gurumayum, Sunil Kumar Dwivedi
    Current Nutrition & Food Science.2024; 20(8): 952.     CrossRef
  • Rising potentials of epigallocatechin gallate (EGCG) loaded lipid-based delivery platforms for breast cancer
    Sagnik Nag, Adrija Bhunia, Sourav Mohanto, Mohammed Gulzar Ahmed, Vetriselvan Subramaniyan
    Discover Applied Sciences.2024;[Epub]     CrossRef
  • Exploring the Role of Artificial Light and Tanning for Skin Cancer
    Muhammad Majid, Abdul Qayoom, Ali Haider
    Indus Journal of Bioscience Research.2024; 2(2): 1506.     CrossRef
  • Exploring the Role of Artificial Light and Tanning for Skin Cancer
    Muhammad Majid, Abdul Qayoom, Ali Haider
    Indus Journal of Bioscience Research.2024; 2(2): 1584.     CrossRef
  • Application of Machine Learning and Deep Learning Models in Prostate Cancer Diagnosis Using Medical Images: A Systematic Review
    Olusola Olabanjo, Ashiribo Wusu, Mauton Asokere, Oseni Afisi, Basheerat Okugbesan, Olufemi Olabanjo, Olusegun Folorunso, Manuel Mazzara
    Analytics.2023; 2(3): 708.     CrossRef
  • 5,221 View
  • 82 Download
  • 2 Web of Science
  • 5 Crossref
Diabetes Prevention and Measures to Ensuring a Healthy Lifestyle during COVID-19 Pandemic and after
Israel Oluwasegun Ayenigbara
Korean J Fam Med 2023;44(1):11-20.   Published online January 19, 2023
DOI: https://doi.org/10.4082/kjfm.21.0216
The incidence of diabetes mellitus (DM) is increasing exponentially globally, with 90% of the confirmed cases being type 2 DM. The global incidence of DM is expected to increase by 48% during 2017–2045. The coronavirus disease 2019 (COVID-19) pandemic continues to have a massive impact on human health, causing sudden lifestyle changes through quarantine measures, such as lockdown, social distancing, various curfews, and isolation at home. This in turn might increase the risk of developing numerous chronic diseases, such as DM, obesity, and cardiovascular diseases, which increase the severity of COVID-19. To this end, we performed a comprehensive review to determine viable measures for the prevention of DM and its subsequent upsurge globally. Additionally, we have determined strategies that should be adopted globally to ensure a healthy lifestyle during the COVID-19 pandemic and later.

Citations

Citations to this article as recorded by  
  • Post-COVID Metabolic Fallout: A Growing Threat of New-Onset and Exacerbated Diabetes
    Shaghayegh Hemat Jouy, Harry Tonchev, Sarah M. Mostafa, Abeer M. Mahmoud
    Biomedicines.2025; 13(6): 1482.     CrossRef
  • Intertwined pathways of SARS-CoV-2 infection and its clinical repercussions on glucose homeostasis: Exploring the rise of new-onset diabetes
    Vertika Awasthi, Rupinder Kaur, Chirag Pasricha, Pratima Kumari, Suruchi Chaubey, Sarita Jangra, Sanjana Mehta, Ravinder Singh
    Obesity Medicine.2025; 56: 100624.     CrossRef
  • Lifestyle prescriptions for diabetes management in primary care: a narrative review
    Hye Jun Lee, Jung-Ha Kim
    Ewha Medical Journal.2025; 48(4): e55.     CrossRef
  • Insulin therapy adherence and associated factors among diabetes mellitus patients in Southern Ethiopia
    Mulualem Gete Feleke, Tadele Lankrew Ayalew, Kidist Ashager, Bizuayehu Atinafu Ataro, Hailu Asmare Beyene
    Diabetes Epidemiology and Management.2025; 19-20: 100284.     CrossRef
  • Enhancement of Virtues: Key to a Healthy Lifestyle against Chronic Diseases and Future Health Crisis
    Dalmacito A. Cordero Jr.
    Korean Journal of Family Medicine.2023; 44(4): 244.     CrossRef
  • 5,050 View
  • 82 Download
  • 3 Web of Science
  • 5 Crossref

Brief Communication

Background

Recently, several institutions, including the American Academy of Sleep Medicine, the Sleep Research Society, and the National Sleep Foundation, have made consensus recommendations concerning appropriate sleep duration for adults. Although numerous studies conducted in Western populations have provided evidence of the harmful effects of short or long sleep duration on mental health, it is still unclear whether these consensus recommendations are appropriate in Korean culture.

Methods

Data from 1,892 subjects with no history of medical or psychiatric diagnoses were selected from the Korea National Health and Nutrition Examination Survey of 2014. Subjects were divided into seven groups based on their sleep duration (≤4, 5, 6, 7, 8, 9, and ≥10 hours). Depressive symptoms were measured using the Patient Health Questionnaire-9 and perceived stress severity was evaluated using a Likert-type scale. Group differences in depressive symptoms and severity of stress were analyzed using an analysis of covariance.

Results

Depressive symptoms in subjects with sleep duration of ≤4 hours (5.7±5.9) or 5 hours (3.4±3.9) were higher than in subjects with a sleep duration of 7 (2.2±2.9) or 8 hours (2.2±2.9) (corrected P<0.05). Furthermore, subjects with a short sleep duration (5 hours or below) had greater perceived stress severity than subjects with a sleep duration of 7 or 8 hours (corrected P<0.05).

Conclusion

Our results suggest that maintaining an appropriate sleep duration as found in the recent consensus recommendation is important for mental health, even in healthy subjects without any medical or psychiatric illnesses, in Korea.

Citations

Citations to this article as recorded by  
  • Association Between Depression and the Short Sleep Duration on Weekdays and Weekends in South Korean Adults: A Cross-Sectional Study Using the 2016 and 2018 Korea National Health and Nutrition Examination Survey
    Mi-Jung Eum, Euna Si
    Healthcare.2025; 13(9): 1043.     CrossRef
  • U-shaped association between average daily sleep duration and depression among individuals with hypertension: a cross-sectional study based on NHANES 2017–2020
    Zhimao Cai, Ye Ye, Sixia Chen, Hualang Cai, Jiashuang Lin, Hui Peng, Wei Yang, Lingli Zeng, Rourou Li, Mengjia Chen, Weifeng Chen
    BMC Psychiatry.2025;[Epub]     CrossRef
  • Relationship between sleep duration and falls in older Mexican Americans: Sex differences in a longitudinal study
    C. Perez, S. Al Snih
    Journal of Psychosomatic Research.2025; 198: 112397.     CrossRef
  • Association of sleep duration and risk of mental disorder: a systematic review and meta-analysis
    Jinhe Zhang, Mengyang He, Xuan Wang, Hairong Jiang, Jinchang Huang, Sixiang Liang
    Sleep and Breathing.2024; 28(1): 261.     CrossRef
  • Mediating roles of sleep quality and resilience in the relationships between chronotypes and mental health symptoms
    Kean Poon, Mimi S. H. Ho, Alan P. L. Tai, Mei-Kei Leung, Meanne C. M. Chan, Way K. W. Lau
    Scientific Reports.2024;[Epub]     CrossRef
  • Sleep patterns and their associations with psychiatric symptoms among Chinese healthcare workers: a latent profile analysis
    Yingjun Xiang, Shujuan Wei, Xiaoya Sun, Weiting Yang, Yaohui Han, Xuanzhen Wu
    Frontiers in Psychology.2024;[Epub]     CrossRef
  • Longitudinal Trends in Sleep and Related Factors Among South Korean Adults From 2009 to 2018
    Jee-Eun Yoon, Dana Oh, Inha Hwang, Jung A Park, Hee-Jin Im, Daeyoung Kim, Kwang Ik Yang, Min Kyung Chu, Chang-Ho Yun
    Journal of Clinical Neurology.2023; 19(4): 392.     CrossRef
  • Prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water and sleep quality in adulthood: a retrospective cohort study
    Charlotte R. Doran, Ann Aschengrau
    Environmental Health.2022;[Epub]     CrossRef
  • Effect of cognitive behavioral therapy program on mental health status among medical student in Palestine during COVID pandemic
    Ahmad Hanani, Manal Badrasawi, Souzan Zidan, Marah Hunjul
    BMC Psychiatry.2022;[Epub]     CrossRef
  • Association of weekend catch-up sleep ratio and subjective sleep quality with depressive symptoms and suicidal ideation among Korean adolescents
    Hyunseo Lee, Yeon-Jeong Kim, Yong-Hyun Jeon, Seung Hoon Kim, Eun-Cheol Park
    Scientific Reports.2022;[Epub]     CrossRef
  • Sleep Pattern Is Related to Mental Health among Chinese Collegiate Student Athletes
    Wei Wei, Weimin Liu
    International Journal of Environmental Research and Public Health.2022; 19(15): 8961.     CrossRef
  • Association between sleep duration and mental health among disabled population over the three-year follow-ups
    Jin-Won Noh, Jae-Hyun Kim, Min-Hee Heo, So Hee Lee
    Journal of Affective Disorders Reports.2022; 10: 100422.     CrossRef
  • The associations between sleep duration, cognitive function, and depressive symptoms: An analysis of Chinese adolescents from China Family Panel Studies
    Tong Zhou, Rui Li, Yan Shi, Gang Tian, Yan Yan
    Journal of Affective Disorders.2022; 319: 252.     CrossRef
  • Comparison of the Associations between Self-Reported Sleep Quality and Sleep Duration Concerning the Risk of Depression: A Nationwide Population-Based Study in Indonesia
    Vivi Leona Amelia, Hsiu-Ju Jen, Tso-Ying Lee, Li-Fang Chang, Min-Huey Chung
    International Journal of Environmental Research and Public Health.2022; 19(21): 14273.     CrossRef
  • Effect of walking behavior on perceived stress based on binary multi-level modeling
    Dianxu Ren, Amy M. Kwon
    Journal of Public Health.2021; 29(2): 427.     CrossRef
  • The Associations between Sleep Duration, Academic Pressure, and Depressive Symptoms among Chinese Adolescents: Results from China Family Panel Studies
    Tong Zhou, Gang Cheng, Xihong Wu, Rui Li, Chao Li, Gang Tian, Simin He, Yan Yan
    International Journal of Environmental Research and Public Health.2021; 18(11): 6134.     CrossRef
  • Association of Nighttime Sleep Duration with Depressive Symptoms and Its Interaction with Regular Physical Activity among Chinese Adolescent Girls
    Xueyin Wang, Jiangli Di, Gengli Zhao, Linhong Wang, Xiaosong Zhang
    International Journal of Environmental Research and Public Health.2021; 18(21): 11199.     CrossRef
  • Association between habitual weekday sleep duration and depressive symptoms among Chinese adolescents:The role of mode of birth delivery
    Lan Guo, Tian Wang, Wanxin Wang, Beifang Fan, Bo Xie, Huimin Zhang, Yuhua Liao, Ciyong Lu
    Journal of Affective Disorders.2020; 265: 583.     CrossRef
  • Association between sleep duration and quality and depressive symptoms among university students: A cross-sectional study
    Wang Li, Jianjun Yin, Xianfeng Cai, Xin Cheng, Yongxiang Wang, Vincenzo De Luca
    PLOS ONE.2020; 15(9): e0238811.     CrossRef
  • Relationships between Physical Activity, Sleeping Time, and Psychological Distress in Community-Dwelling Elderly Japanese
    Yukio Yamamoto, Hiromi Suzuki, Yutaka Owari, Nobuyuki Miyatake
    Medicina.2019; 55(7): 318.     CrossRef
  • 7,988 View
  • 95 Download
  • 20 Web of Science
  • 20 Crossref

Original Articles

Association between Sedentary Time and Cardiovascular Risk Factors in Korean Adults
Jae-Hong Park, Hee-Kyung Joh, Gyeong-Sil Lee, Sang-Jun Je, Soo-Hwan Cho, Soo-Jin Kim, Seung-Won Oh, Hyuk-Tae Kwon
Korean J Fam Med 2018;39(1):29-36.   Published online January 23, 2018
DOI: https://doi.org/10.4082/kjfm.2018.39.1.29
Background

Sedentary behavior has been shown to have deleterious effects on cardiovascular outcomes. This study aimed to examine the association between sedentary time and cardiovascular risk factors in Korean adults.

Methods

A cross-sectional study was performed using data from adults aged 19 years and above in the 2013 Korean National Health and Nutrition Examination Survey. Sedentary time was self-reported and categorized into quintiles. Cardiovascular risk factors, including blood pressure (BP), total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, low-density lipoprotein cholesterol, and fasting glucose levels, were categorized into dichotomous variables according to the Adult Treatment Panel III criteria. Multivariate logistic regression was performed with adjustment for various demographic and lifestyle variables, body mass index (BMI), waist circumference (WC), and moderate-to-vigorous physical activity. Complex sampling design was used, and survey weights and sample design variables were applied in analyses.

Results

A total of 3,301 individuals were included in the analyses, and mean sedentary time was 6.1 h/d. Prolonged sedentary time was significantly associated with high diastolic BP (top vs. bottom quintile: adjusted odds ratio [OR], 1.71; 95% confidence interval [CI], 1.09–2.68; Ptrend=0.03) and low HDL cholesterol level (top vs. bottom quintile: adjusted OR, 1.42; 95% CI, 1.02–1.98; Ptrend=0.02) after adjustment for BMI, WC, moderate-to-vigorous physical activity, and other variables. No significant associations were found between sedentary time and other cardiovascular risk factors.

Conclusion

Prolonged sedentary time was significantly associated with high diastolic BP and low HDL cholesterol level in Korean adults. The associations were independent of general and abdominal obesity and moderate-to-vigorous physical activities.

Citations

Citations to this article as recorded by  
  • Deliberating Effects of Sedentary Lifestyle on Young Adults: A Review of Literature
    Hira Iqrar, Maham Mohsin, Vaneeza Ahmad, Misbah Qayum, Wajida Perveen
    Pakistan BioMedical Journal.2025; : 02.     CrossRef
  • Correlation of Working Style to Stress, Coping Mechanism and Metabolic Syndrome Risk in Sedentary Workers
    Dominikus Raditya Atmaka, Shintia Yunita Arini, Bian Shabri Putri Irwanto, Asri Meidyah Agustin, Aliffah Nurria Nastiti, Muh. Agus Prianto, Andi Suci Rahman
    The Indonesian Journal of Occupational Safety and Health.2025; 14(1): 15.     CrossRef
  • Physical activity time and lifestyle correlates of cardiovascular disease status in older adults in Accra
    Nestor Asiamah, Kyriakos Kouveliotis, Carl Petersen, Richard Eduafo, Richard Borkey
    Journal of Public Health.2023; 31(9): 1453.     CrossRef
  • Associations between objectively measured patterns of sedentary behaviour and arterial stiffness in Chinese community-dwelling older women
    Litao Du, Guangkai Li, Pengfei Ren, Qiang He, Yang Pan, Si Chen, Xianliang Zhang
    European Journal of Cardiovascular Nursing.2023; 22(4): 374.     CrossRef
  • Detrimental Impact of Sedentary Behaviour on Health
    Suriya Kumareswaran
    European Journal of Medical and Health Sciences.2023; 5(1): 18.     CrossRef
  • Does the built environment influence location- and trip-based sedentary behaviors? Evidence from a GPS-based activity space approach of neighborhood effects on older adults
    C. Perchoux, R. Brondeel, S. Klein, O. Klein, B. Thierry, Y. Kestens, B. Chaix, P. Gerber
    Environment International.2023; 180: 108184.     CrossRef
  • Is Sedentary Behavior a Novel Risk Factor for Cardiovascular Disease?
    Andrea T. Duran, Emily Romero, Keith M. Diaz
    Current Cardiology Reports.2022; 24(4): 393.     CrossRef
  • Heart Rate Recovery as an Assessment of Cardiorespiratory Fitness in Young Adults
    J. Matthew Thomas, W. Scott Black, Philip A. Kern, Julie S. Pendergast, Jody L. Clasey
    Journal of Clinical Exercise Physiology.2022; 11(2): 44.     CrossRef
  • TV time, physical activity, sedentary behaviour and cardiometabolic biomarkers in pregnancy—NHANES 2003–2006
    Brittany A. Matenchuk, Valerie Carson, Laurel A. Riske, Allison Carnio, Margie H. Davenport
    Canadian Journal of Public Health.2022; 113(5): 726.     CrossRef
  • Improved self‐esteem and activity levels following a 12‐week community activity and healthy lifestyle programme in those with serious mental illness: A feasibility study
    Peter Gallagher, Cailín Boland, Aisling McClenaghan, Felicity Fanning, Elizabeth Lawlor, Mary Clarke
    Early Intervention in Psychiatry.2021; 15(2): 367.     CrossRef
  • The Built Environment and Socio-Demographic Correlates of Partial and Absolute Sedentary Behaviours in Community-Dwelling Older Adults in Accra, Ghana
    Nestor Asiamah, Carl Petersen, Kyriakos Kouveliotis, Richard Eduafo
    Journal of Cross-Cultural Gerontology.2021; 36(1): 21.     CrossRef
  • Nuances between sedentary behavior and physical inactivity: cardiometabolic effects and cardiovascular risk
    Erika Andressa Simões de Melo, Laryssa Elza de Santana Ferreira, Rodolfo José Ferreira Cavalcanti, Carlos Alberto de Lima Botelho Filho, Matheus Rodrigues Lopes, Romero Henrique de Almeida Barbosa
    Revista da Associação Médica Brasileira.2021; 67(2): 335.     CrossRef
  • Effects of Living Alone and Sedentary Behavior on Quality of Life in Patients With Multimorbidities: A Secondary Analysis of Cross-Sectional Survey Data Obtained From the National Community Database
    Young Eun AHN, Chin Kang KOH
    Journal of Nursing Research.2021; 29(5): e173.     CrossRef
  • Run, lift, or both? Associations between concurrent aerobic–muscle strengthening exercise with adverse cardiometabolic biomarkers among Korean adults
    Jason A Bennie, Ding Ding, Asaduzzaman Khan, Emmanuel Stamatakis, Stuart JH Biddle, Junghoon Kim
    European Journal of Preventive Cardiology.2020; 27(7): 738.     CrossRef
  • Effect of Sedentary Time on the Risk of Orthopaedic Problems in People Aged 50 Years and Older
    S.H. Kang, J.H. Joo, E.C. Park, Sung-In Jang
    The Journal of nutrition, health and aging.2020; 24(8): 839.     CrossRef
  • Objectively Measured Sedentary Behavior and Cardiovascular Disease Risk Factors
    Hoyong Sung, Jungjun Lim, Junbae Mun, Yeonsoo Kim
    The Korean Journal of Sports Medicine.2020; 38(3): 143.     CrossRef
  • Sedentary Lifestyle and Cardiovascular Health
    Soo Young Kim
    Korean Journal of Family Medicine.2018; 39(1): 1.     CrossRef
  • The effects of high-intensity interval training on reverse cholesterol transport elements: A way of cardiovascular protection against atherosclerosis
    Saleh Rahmati-Ahmadabad, Hossein Shirvani, Abbass Ghanbari-Niaki, Fatemeh Rostamkhani
    Life Sciences.2018; 209: 377.     CrossRef
  • 8,905 View
  • 130 Download
  • 17 Web of Science
  • 18 Crossref
The Effect of Lifestyle Changes on Blood Pressure Control among Hypertensive Patients
Myung Hwa Yang, Seo Young Kang, Jung Ah Lee, Young Sik Kim, Eun Ju Sung, Ka-Young Lee, Jun-Su Kim, Han Jin Oh, Hee Chul Kang, Sang Yeoup Lee
Korean J Fam Med 2017;38(4):173-180.   Published online July 20, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.4.173
Background

Hypertension is highly prevalent among patients who visit primary care clinics. Various factors and lifestyle behaviors are associated with effective blood pressure control. We aimed to identify factors and lifestyle modifications associated with blood pressure control among patients prescribed antihypertensive agents.

Methods

This survey was conducted at 15 hospital-based family practices in Korea from July 2008 to June 2010. We prospectively recruited and retrospectively assessed 1,453 patients prescribed candesartan. An initial evaluation of patients' lifestyles was performed using individual questions. Follow-up questionnaires were administered at 4, 8, and 12 weeks. We defined successful blood pressure control as blood pressure <140 mm Hg systolic and <90 mm Hg diastolic.

Results

Of the 1,453 patients, 1,139 patients with available data for initial and final blood pressures were included. In the univariate analysis of the change in performance index, weight gain (odds ratio [OR], 2.18; 95% confidence interval [CI], 1.52 to 3.11; P<0.001), physical inactivity (OR, 1.195; 95% CI, 1.175 to 3.387; P=0.011), and increased salt intake (OR, 1.461; 95% CI, 1.029 to 2.075; P=0.034) were related to inadequate blood pressure control. Salt intake also showed a significant association. Multivariate ORs were calculated for age, sex, body mass index, education, income, alcohol consumption, smoking status, salt intake, comorbidity, and family history of hypertension. In the multivariate analysis, sex (OR, 3.55; 95% CI, 2.02 to 6.26; P<0.001), salt intake (OR, 0.64; 95% CI 0.43 to 0.97; P=0.034), and comorbidity (OR, 1.82; 95% CI, 1.23 to 2.69; P=0.003) were associated with successful blood pressure control.

Conclusion

Weight gain, physical inactivity, and high salt intake were associated with inadequate blood pressure control.

Citations

Citations to this article as recorded by  
  • Effectiveness of health promotion utilizing word puzzle games in enhancing older adults' knowledge and attitudes regarding hypertension management
    Mia Fatma Ekasari, Aan Nurhasanah, Eros Siti Suryati, Puspita Hanggit Lestari, Siti Badriah, Ahmad Jubaedi
    Healthcare in Low-resource Settings.2025;[Epub]     CrossRef
  • Joint Association of Physical Activity and Sleep Quality With Blood Pressure Control in Patients With Hypertension in Douala, Cameroon
    Elysée Claude Bika Léle, Audrey Liza Tadjoua Nenoh, Jerson Mekoulou Ndongo, Marie Solange Ndom Ebongue, Hermann Tsague Kengni, Siddick Mouliom, Wiliam Richard Guessogo, Viché Lade, Xavier Kuelang, Manuela Kamdem, Djibrilla Siddikatou, Valérie Ndobo, Samue
    Journal of Physical Activity and Health.2025; 22(5): 582.     CrossRef
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    Haili Lai, Xiaoqin Xin
    Frontiers in Public Health.2025;[Epub]     CrossRef
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    Bandar A Almabruk, Lana S Alturki, Abdullah M Alghamdi, Turki S Almutairi, Eman A Alsulami, Ahad S Alsharif, Lamiaa Saad, Showq A Alsaedi, Ola E Alkhoshiban, Nouf Alshareef, Loai A AlRabaie, Abeer Alsharif, Layan Y Khan, Talal W Bakhsh
    Cureus.2025;[Epub]     CrossRef
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    Yusuf Ari Mashuri, Vitri Widyaningsih, Alimah Premanawasti, Jaap Koot, Zinzi Pardoel, Jeanet Landsman-Dijkstra, Maarten Postma, Ari Probandari, Muhammad Maaz Arif
    PLOS ONE.2024; 19(5): e0303503.     CrossRef
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    Shweta Malakar, Shivendra Kumar Singh, Kauser Usman
    Cureus.2024;[Epub]     CrossRef
  • Evaluating the Effectiveness of Lifestyle Modifications in Managing Hypertension Among Adults
    Ali Khalid, Ayesha Khalid, Ayesha Tariq, Ume Aiman, Mahnoor Imtiaz, Roshan Ahmad, Fatima Naeem, Umer Saeed Ansari
    DEVELOPMENTAL MEDICO-LIFE-SCIENCES.2024; 1(7): 4.     CrossRef
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    Lin Yang, Zhi Zhang, Changqing Du, Lijiang Tang, Xiaowei Liu
    BMC Public Health.2024;[Epub]     CrossRef
  • Neurogenic Hypertension, the Blood–Brain Barrier, and the Potential Role of Targeted Nanotherapeutics
    Richard Nii Lante Lamptey, Chengwen Sun, Buddhadev Layek, Jagdish Singh
    International Journal of Molecular Sciences.2023; 24(3): 2213.     CrossRef
  • Can omega-3 fatty acids and vitamin E co-supplementation affect obesity indices?
    Vali Musazadeh, Arash Tandorost, Meysam Zarezadeh, Jaber Jafarzadeh, Zoha Ghavami, Parsa Jamilian, Alireza Ostadrahimi
    International Journal for Vitamin and Nutrition Research.2023; 93(5): 471.     CrossRef
  • Plant-food-derived Bioactives in Managing Hypertension: From Current Findings to Upcoming Effective Pharmacotherapies
    Monica Butnariu, Deborah Fratantonio, Jesús Herrera-Bravo, Sonal Sukreet, Miquel Martorell, Garsiya Ekaterina Robertovna, Francisco Les, Víctor López, Manoj Kumar, Marius Pentea, Ioan Sarac, Alexandra Becherescu, Natália Cruz-Martins, William N. Setzer, M
    Current Topics in Medicinal Chemistry.2023; 23(8): 589.     CrossRef
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    Dhurvendra Pandey, Sunil kant Guleri, Umesh Sinha, Smriti Pandey, Shivam Tiwari
    Asian Journal of Pharmaceutical and Clinical Research.2023; : 44.     CrossRef
  • Lifestyle Modification Determinants of Blood Pressure Status Awareness amongst Traders in A Market Community North Central Nigeria
    David Aondona Daniel, Nndunno Asheku Akwaras, Abraham Kohol, Paul Tersur Apande, Fanen Dogoh, Kashimana Tyovenda
    European Journal of Medical and Health Sciences.2023; 5(3): 39.     CrossRef
  • A Retrospective Cohort Study of the Association Between Calcium Serum Level and Hypertension in Older Adults
    Zia Sabah, Ahmed S Al Zomia, Mosab Deajim, Abdulrahman Alshahrani, Abdullah H Alamri, Ali M Alqahtani, Lama A Lahiq, Nasser A Alwaqdi, Berin Raj
    Cureus.2023;[Epub]     CrossRef
  • A Community Trial in Coastal Karnataka using Life Style Modifications to Assess its Impact on Hypertension and Diabetes
    Rashmi Kundapur, Bhavesh Modi, Anusha Rashmi, Roopa R. Mendagudli, V Sunhitha, Deepak Saxena
    Indian Journal of Community Medicine.2023; 48(5): 684.     CrossRef
  • The Impact of Non-pharmacological Interventions on Blood Pressure Control in Patients With Hypertension: A Systematic Review
    Omar M Ballut, Abdulrahman A Alzahrani, Raghad A Alzahrani, Aghnar T Alzahrani, Reem A Alzahrani, Mohammad F Alzahrani, Yousef K Alzahrani, Nouf A Alghamdi, Raghad H Alghamdi
    Cureus.2023;[Epub]     CrossRef
  • Determinants of Blood Pressure Control among Hypertensive Patients Attending a Rural Teaching Hospital in Southern Nigeria
    TIA Oseni, A Emonriken, SD Ahmed, M Dic-Ijiewere
    Nigerian Journal of Clinical Practice.2023; 26(3): 260.     CrossRef
  • Wearable technology-delivered lifestyle intervention amongst adults with overweight and obese: A systematic review and meta-regression
    Sai Ho Wong, Zhen Yang Abel Tan, Ling Jie Cheng, Siew Tiang Lau
    International Journal of Nursing Studies.2022; 127: 104163.     CrossRef
  • Self-care practice among adult hypertensive patients at ambulatory clinic of tertiary teaching Hospital in Ethiopia: a cross-sectional study
    Tsegaye Melaku, Bodena Bayisa, Helen Fekeremaryam, Alemayehu Feyissa, Alemayehu Gutasa
    Journal of Pharmaceutical Policy and Practice.2022;[Epub]     CrossRef
  • Blood pressure control status of patients with hypertension on treatment in Dessie City Northeast Ethiopia
    Zinabu Fentaw, Kidist Adamu, Shambel Wedajo
    BMC Public Health.2022;[Epub]     CrossRef
  • The association between organophosphate insecticides and blood pressure dysregulation: NHANES 2013–2014
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Review Article

Physical Inactivity, Sedentary Behavior and Chronic Diseases
Karimé González, Jorge Fuentes, José Luis Márquez
Korean J Fam Med 2017;38(3):111-115.   Published online May 23, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.3.111

New research into physical activity suggests that it is no longer sufficient just to meet minimum levels recommended by health guidelines in order to reduce cardiovascular risk. Both physical inactivity and sedentary behavior have their own health hazards and need to be addressed separately, in order to explore their different deleterious mechanisms. The aim of this review was to define and to characterize both concepts, and their relationship with major non-communicable chronic diseases. A PubMed database search was undertaken, using the following key words: physical activity, physical inactivity, sedentarism, sedentary behavior, and non-communicable chronic disease. This literature review provides an updated view on physical inactivity and sedentary behavior, and reevaluates their prevalence and association with major non-communicable chronic disease.

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Original Articles
Lifestyle Habits Related to Abdominal Obesity in Korean Adolescents.
Won Chin Chung, Young Gyu Cho, Jae Heon Kang, Hyun Ah Park, Kyoung Woo Kim, Joo Ho Kang, Nu Ri Kim, Hye Jin Kim, Ok Hyun Kim
Korean J Fam Med 2010;31(7):547-554.   Published online July 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.7.547
Background
It has been reported that the abdominal obesity can cause various metabolic abnormalities not only in adults but also in adolescents. This study was conducted to investigate lifestyle habits related to abdominal obesity in Korean adolescents. Methods: This study is a cross-sectional study on 561 adolescents (305 boys and 256 girls) aged 12-18 years from the Korean National Health and Nutrition Examination Survey 2005. The abdominal obesity was defined as waist circumference at or above the 90th percentile for each age and gender based on the 2007 growth chart for Korean children. The frequency of physical activity, screen time, and the intake amount of energy and macronutrients were investigated as lifestyle habits. Results: The prevalence of abdominal obesity in Korean adolescents aged 12-18 years was 9.1% (Boys, 9.4%; Girls, 8.7%). The mean of daily screen time was 4.3 ± 0.1 hours (Boys, 4.4 ± 0.2 hours; Girls, 4.2 ± 0.2 hours). The subjects with daily screen time ≥ 5 hours had a 3.0 times increased risk of abdominal obesity compared to subjects with daily screen time < 3 hours (P-value = 0.004). The adjusted odds ratio of fat intake ≥ 35% of energy was 2.57 (95% confidence interval, 1.16 to 5.68; P-value = 0.020) with fat intake < 25% of energy as reference. The relationship between long screen time and abdominal obesity was observed in girls and high fat intake was related to abdominal obesity in boys. Conclusion: This study shows that abdominal obesity in Korean adolescents is associated to long screen time and high fat intake.

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    Joon Young Kim, Kyungchul Song, Youngha Choi, Byung-Sun Choi, Hyun Wook Chae
    Frontiers in Nutrition.2025;[Epub]     CrossRef
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The Association between Marital Status and Metabolic Syndrome in Korean Men.
Tae Heum Chung, Moon Chan Kim, Chung Hun Choi, Chang Sup Kim
Korean J Fam Med 2010;31(3):208-214.   Published online March 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.3.208
Background
We aimed to investigate the association between marital status and metabolic syndrome, and observed how their lifestyle may influence within their relationship. Methods: We analyzed the data from 12,288 Korean men over 20 years old taking a health checkup in a university hospital in Ulsan from March 2008 to February 2009. The subjects were classified as married, unmarried, separated, widowed, and divorced. The odds ratios for metabolic syndrome in each marital status were calculated after adjusting for age, educational level, and family income. In only married men and divorced men, odds ratios were calculated again after adjusting for alcohol intake, smoking, or exercise added to age, educational level, and family income. Results: After adjustment for age, educational level, and family income, the odds ratio for metabolic syndrome in divorced men was 1.48 (95% confidence internal [CI], 1.03 to 2.12; P = 0.03) compared to married men. However, the odds ratios in divorced men decreased to 1.47 (95% CI, 0.97 to 2.24; P = 0.07) after adjusting for alcohol intake added to age, educational level, and family income, 1.42 (95% CI, 0.99 to 2.04; P = 0.06) after adjusting for smoking added, 1.35 (95% CI, 0.93 to 1.96; P = 0.12) after adjusting for exercise added, and 1.37 (95% CI, 0.89 to 2.12; P = 0.15) after adjusting for alcohol intake, smoking, and exercise added. Conclusion: Divorced men were likely to have metabolic syndrome compared to married men and this finding may be mediated by their bad lifestyle.

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    Vahid Gharibi, Narges Khanjani, Ahmad Khosravi, Majid Bagheri Hossein Abadi, Pirasteh Norouzi, Mohammad Khammarnia
    Work.2020; 65(1): 127.     CrossRef
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    Young-Ah Jung, Li-Ly Kang, Ha-Nui Kim, Hoon-Ki Park, Hwan-Sik Hwang, Kye-Yeung Park
    Korean Journal of Family Medicine.2018; 39(5): 307.     CrossRef
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Complaints of Fatigue and Dietary Life in Medical Students.
Sung Min Lee, Sung Gon Lee, Jae Eun Lee, Eun Hee Kong, Jong Soon Choi
Korean J Fam Med 2009;30(11):880-886.   Published online November 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.11.880
Background
Fatigue is a common problem in medical students and is thought to be related to poor academic performance. Fatigue is expected to be highly related to dietary habits, but previous research was not enough. Therefore, the aims of this study were to investigate the relationship between dietary habits and the prevalence of fatigue and also to give an update on basic research data for improving academic performance in medical students. Methods: The study group consisted of 170 healthy second-year medical students attending three university school of medicine in Busan. They completed a questionnaire dealing with fatigue (Fatigue Severity Scale), dietary habits, lifestyle, and academic performance. Results: On multivariate logistic regression analyses, skipping breakfast (completely skipping breakfast everyday versus having breakfast everyday; odds ratio 7.23; 95% confi dence interval, 2.07 to 25.28; P = 0.002) was positively correlated with the complaints of fatigue. Conclusion: Skipping breakfast was associated with the complaints of fatigue in medical students.
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Lifestyle and Cardiovascular Risk Factors in Divorced Male Workers.
Min Woo Park, Tae Heum Chung, Chang Sup Kim, Mun Chan Kim, Deuk Kee Lee
Korean J Fam Med 2009;30(10):784-789.   Published online October 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.10.784
Background
Considering the unhealthy lifestyle observed in divorced men, we planned this study to compare the lifestyle and cardiovascular risk factors between married and divorced man. Methods: A total of 11,855 male workers took a health check-up in a University Hospital in Ulsan from March to December 2004. One hundred eight workers were recognized to have checked affi rmative on "divorced" check item on the marital status and 400 workers were matched for age and randomly selected from the "married" 10,177 workers. Comparison was performed between the two groups with the results of the main laboratory data and self-recorded life style questionnaire. Results: The divorced men were shorter in height than the married men (P = 0.022), and showed significantly higher diastolic blood pressure (P = 0.033) and gamma-glutamyl transferase (P = 0.001). In lifestyle, the divorced men had signifi cantly lower educational level, lower monthly household income, higher smoking rate, and more frequent irregular meals than the married men. Divorcing had 1.88 times the odds of having higher diastolic blood pressure compared to staying married. Conclusion: The divorced men had poorer lifestyle and higher diastolic blood pressure than the married men.
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Determinants of Responsiveness of LDL-cholesterol Lowering to Lifestyle Modification in Hypercholesterolemic Patients.
Hea Jin Lee, Young Won Seo, Kyung Eun Yun, Hye Soon Park
Korean J Fam Med 2009;30(5):369-377.   Published online May 10, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.5.369
Background
Current guidelines for the treatment of hyperlipidemia propose lifestyle modification as a first-line intervention. The aim of this study was to identify the factors which determine responsiveness of LDL-cholesterol lowering to lifestyle modifi cation in hypercholesterolemic patients.Methods: A total of 109 patients aged between 30 and 70 years (52 men and 109 women) who were diagnosed with hypercholesterolemia between July 2007 and February 2008 at Asan Medical Center were enrolled in this study. The patients were educated on lifestyle modifi cations by trained family physicians. We measured clinical, anthropometric, lifestyle parameters and lipid profiles initially and at eight weeks after education. Stepwise multiple linear regression models were used to assess covariates and variance components.Results: The serum level of LDL-cholesterol decreased in both women (8.0 ± 15.37%, P < 0 .001) and men (4.95 ± 9.81%, P < 0.001). In women, dietary adherence (Ղ = 0.267, P = 0.004), change in physical activity duration (Ղ = 0.196, P = 0.034) and menopausal state (Ղ = -0.207, P = 0.026) were signifi cant predictors in response of percent change in LDL- cholesterol. In men, dietary adherence (Ղ = 0.372, P = 0.007) was a predictor in response of percent change in LDL-cholesterol.Conclusion: Adherence to lifestyle modifi cation was a main factor which had infl uenced on response of percent change in LDL-C levels. In women, however, menopausal state was also an important factor.

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The Effect of Lifestyle Modification Program for Medical Students' Personal Health Practices.
Si Won Hur, Hyun Su Kim, Ji Young Son, Woo Kyoung Bae, Tae Woo Yoo, Yeon Ji Lee
Korean J Fam Med 2009;30(4):277-284.   Published online April 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.4.277
Background
Lifestyle is an important risk factor for many diseases. We need to educate medical students for advocating health promoting behaviors to their patients. Teaching knowledge, however, was not enough for medical students to change their health-related lifestyle. In this study, we investigated health promoting behaviors of medical students, and the improvement of their health behaviors after competitive lifestyle modifi cation program.Methods: All sophomores of medical college in Seoul National University were included in this study. We performed lifestyle modifi cation program consisting of lecture, group competition, and feedback. We focused on reforming health behaviors like smoking, drinking, exercise, stress management and eating habits. And we also checked common symptoms of functional diseases, medication frequency for relieving these symptoms and general life satisfaction.Results: After 2 months of lifestyle modifi cation program, the obese (P = 0.0455) and the average value of BMI (P < 0.001) were decreased and two of smokers quitted smoking. Numbers of medical students with health related habits such as regular exerciser (P = 0.027), frequent user of symptom-relief medication (P < 0.001), breakfast skipper (P = 0.005) were signifi cantly changed in positive way, and the average value of general life satisfaction score (P = 0.003) was improved.Conclusion: Lifestyle modification program improved medical students' health habits and enhanced general life satis-faction.

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Health Behavior and Metabolic Syndrome.
Jeong Dae Oh, Sangyeoup Lee, Jeong Gyu Lee, Young Joo Kim, Yun Jin Kim, Byung Mann Cho
Korean J Fam Med 2009;30(2):120-128.   Published online February 10, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.2.120
Background
Life style has been shown to improve risk factor comprising the metabolic syndrome. Metabolic syndrome is prime candidate for lifestyle modification utilizing the tools of exercise, nutritional therapy so on. Therefore, we examined the prevalence of metabolic syndrome according to health behaviors. Methods: The 1,240 adults were recruited into this cross-sectional study. Subjects examined body mass index, waist circumference, blood pressure, lipid profile. Medical history was reviewed and daily calorie intake examined by food frequency questionnaire. Six healthy behavior-sleeping hours, smoking, drinking, exercise, calorie intake and boey weight of subjects were examined. Each heathy behaviors were categorized as a three groups. Metabolic syndrome were diagnosed by ATP III criteria. Results: The study subjects were consisted of 57.1% men and 42.9% women. The prevalence of metabolic syndrome was 14.3%. The prevalence of metabolic syndrome was lower in group with good healthy behaviors. Subjects with more good healthy behaviors had lower prevalence of metabolic syndrome than with less good healthy behaviors(0, 50.0%; 1, 41.0%; 2, 30.6%; 3, 13.8%; 4, 8.5%; 5, 5.3%; and 6, 4.3%). Relative to subjects with high good health behavior score, those with low good health behavior score were at significantly increased risk of metabolic syndrome (odds ratio=4.25, 95% CI 2.97-6.08). Conclusion: Subjects with greater good healthy behaviors had a substantially lower risk of being diagnosed with the metabolic syndrome compared those with lower good healthy behaviors. This finding suggests that lifestyle modification may be appropriate as a first-line intervention to metabolic syndrome.

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The Relationships between Parental Lifestyle Habits and Children's Overweight.
Sung Won Kim, Young Gyu Cho, Jae Heon Kang, Sung Hee Lee, Ji Eun Lee, Hyun Ah Park, Hye Ryoung Song, Ji Hyun Song
J Korean Acad Fam Med 2008;29(6):395-404.   Published online June 10, 2008
Background
Children of obese parents are more likely to be obese themselves. Parental lifestyle habits could induce or aggravate children's obesity. This study was conducted to assess the relationship between parental lifestyle habits and children's overweight. Methods: Children who were enrolled in this study were first grade students from elementary schools in Gwacheon and Seoul. A total of 121 children (50 overweight children and 71 normal weight children) and their parents underwent anthropometric measurements and also were surveyed by a questionnaire. Results: The children of obese parents were more likely to be diagnosed as overweight compared to the children whose parents were normal weight (Father: P=0.037, Mother: P=0.001). Among the paternal lifestyle habits, hours of watching TV or computer usage (adjusted odd ratio =2.08, 95% CI=0.90∼4.80) and eating frequency of soda, ice cream, cake and chips (adjusted OR=5.77, 95% CI=1.65∼20.22) were found to be related to their children being overweight. Among the maternal lifestyle habits, hours of watching TV or computer usage (adjusted OR=2.35, 95% CI=0.99∼5.58), the frequency of eating breakfast (adjusted OR: 2.48, 95% CI=1.07∼5.75) and the frequency of overeating (adjusted OR: 2.15, 95% CI=0.91∼5.11) were found to be related to their children being overweight. Additive adjustment of children's lifestyle habits made the relationship between maternal lifestyle habits and children's overweight reduced. However, the odds ratio of paternal lifestyle habits was not reduced. Conclusion: Parental obesigenic lifestyle habits were related to children's overweight. Maternal lifestyle habits could affect her children's weight via an effect on her children's lifestyle habits. (J Korean Acad Fam Med 2008; 29:395-404)
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Lifestyle and Health State in Individuals with Frequent Nocturnal Sleep Interruption.
Joon Sik Seo, Jae Ho Lee, Kang Kon Lee
J Korean Acad Fam Med 2006;27(12):967-974.   Published online December 10, 2006
Background
: Many studies have demonstrated that excessively long or short sleep duration and insomnia are associated with high risk of mortality. We intended to investigate the lifestyle and the state of health in frequently sleep interrupted people.

Methods : We have examined 2,540 subjects who visited a comprehensive medical testing center from January 2001 to June 2003. We divided into two groups of sleep disturbance into frequently interrupted group (two or more times per night) and infrequently interrupted group (less than twice per night). After frequency matching by age and sex, 1,900 subjects (each group of 950 subjects) were selected. Lifestyle, self-health perception, symptoms, clinical laboratory data and past history were compared by chi-square test and student's t-test. To identify the factors that influenced on sleep interruption, multiple logistic regression analysis was done.

Results : Sleep duration was not significantly different in both groups (P=0.486). The frequently interrupted group were likely to perceive themselves as bad state of health being in a (P=0.008) and to complain of various symptoms, i.e., fatigue (P<0.001), headache (P= 0.001), etc. Also, they had more incidence of mood disorders (P= 0.002), fatty liver (P=0.008), and arthritis (P=0.001) than the other group. By multiple logistic regression analysis, alcohol consumption (OR: 1.344, P= 0.007), irregular diet (OR: 1.325, P=0.003), and coffee intake (OR: 0.786, P= 0.013) were significantly different between the frequently interrupted group and the other group.

Conclusion : Patients who complain of insomnia should be evaluated on both sleep duration and interruption. The evaluation of sleep interruption is needed in patients who perceive themselves as being in a bad state of health, who complain of various symptoms (fatigue, headache, etc.), or have a history of mood disorder, fatty liver, or arthritis.
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The Lifestyle associated with Weight Gain and Persistent Overweight for 2 Years among Hospital Workers.
Sang Lo Lee, Ka Young Lee, Tae Jean Park, Young Bae June, Young Woo Son
J Korean Acad Fam Med 2005;26(11):680-685.   Published online November 10, 2005
Background
: The purpose of this study was to assess the lifestyle associated with weight gain and persistent overweight for 2 years.

Methods : The subjects were 580 workers (109 men, 471 women) at one university affiliated hospital. Their height and weight were measured twice in 2000 and 2002. A questionnaire, about lifestyle was filled out in 2000. The questionnaire included the average amount of alcohol intake and the number of days per week in which alcohol was consumed, smoking status, and the number of days per week in which exercise was done. Their weight change in 2 years was calculated and their weight status was classified into two groups: persistent normal weight (BMI<23 kg/m2) and persistent overweight (BMI≥23 kg/m2).

Results : Among the total, 54.3% of men and 10.0% of women had persistent overweight over 2 years. Overall 93.4% of overweight men and 68.7% of overweight women remained overweight after 2 years. Compared with male non-smokers and male ex- smokers, current male smokers gained weight as much as 1.17 kg over 2 years after adjusting for age and initial BMI (P=0.033). Compared with females who exercised less than 3 per week, those who exercised 3 or more per week lost weight as much as 1.21 kg over 2 years after adjusting for age and initial BMI (P=0.005). Compared with males who consumed alcohol an average of ≤30 g per consumption, those who consumed an average of >30 g were 4.1 times (95% C.I. 1.04∼16.21) more likely to maintain persistent overweight over 2 years after adjustment for age and frequency of alcohol use. However no particular lifestyle was shown to predict the risk of persistent overweight for women.

Conclusion : Regular exercise of moderate intensity and modest alcohol consumption seemed to prevent weight gain and persistent overweight. Such lifestyle may be encouraged to maintain healthy weight.
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Lifestyles and Gastrointestinal Disorders in Those Who Have a Postprandial Lying-down Habit.
Yong Min Ko, Jae Ho Lee, Joon Sik Seo, Joon Young Yoo, Kyu Suck Kang, Yong Chul Kim
J Korean Acad Fam Med 2004;25(12):887-894.   Published online December 10, 2004
Background
: A habit of lying-down after eating is known as a risk factor of reflux esophagitis. However the association between gastrointestinal disorders and a postprandial lying-down habit has not yet been identified. Some people believe that lying-down after meals is helpful for their health. We intended to investigate the relationship between such a habit and the health lifestyles, gastrointestinal symptoms, disorders using a questionnaires and gastrofiberscopic results of patients who visited our general health screening center.

Methods : We examined 1,030 subjects (the frequent postprandial lying-down group was 576 persons (57.7%), the rare group was 436 persons (42.3%) who visited our general health screening center for a routine check-up including a gastrofiberoscopy during the period between January 2001 to December 2002. After frequency matching by age and sex, health lifestyles (such as smoking, alcohol consumption, exercise, eating habits, night time sleep duration and awakening frequency, nap, and coffee intake), gastrointestinal symptoms (dyspepsia, epigastric pain, heart burn, chest pain, and constipation) and gastrofiberoscopic findings were compared using results from the questionnaires and gastrofiberscopic findings. Factors such as gastritis and reflux esophagitis were set as dependent variables, while postprandial lying-down was set as an independent variable. The frequent postprandial lying-down group and the rare group were analysed through stepwised multiple logistic regression analysis.

Results : Subjects with a frequent postprandial lying- down habit showed a significantly greater degree in alcohol consumption (P=0.010), irregular eating habits (P<0.001), eating between meals (P<0.001), napping (P<0.001), and night time awakening frequency (P= 0.016) than the rare group did. In addition, chest pain (P=0.031) and constipation (P=0.010) were more common in the frequent postprandial lying-down group. However, prevalence of dyspepsia (P=0.147), epigastric pain (P=0.085), and heartburn (P=0.700) showed no differences between the two groups. Being controlled with age, sex, education level, body mass index, and life style factors, postprandial lying-down group showed higher prevalence ratios in erythematous gastritis (OR 1.59; P=0.090), atrophic gastritis (OR 1.71; P= 0.059), and reflux esophagitis (OR 1.78; P=0.103).

Conclusion : A postprandial lying-down habit is associated with undesirable lifestyles and some gastrointestinal disorders. Therefore, a modification of the postprandial lying-down habit should be recommended. Further investigation is needed to clarify the causal relationships between a postprandial lying down habit and gastrointestinal symptoms and disorders.
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Relation of Lifestyle Variables to Total Mortality in a Cohort of Old Residents Aged 60-64 in a Rural Community.
Chan Hyang Park, Choong Won Lee, Bog Sang Ko
J Korean Acad Fam Med 2002;23(10):1219-1228.   Published online October 10, 2002
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Lifestyle Factors Related to Constipation in Working Women.
Hwee Soo Jung, Yun Mi Song, Jung Kwon Lee, Young Wook Kim, Seung Heon Han, Seok Cheol Kang, Yoong Eun Kim
J Korean Acad Fam Med 2002;23(9):1124-1132.   Published online September 10, 2002
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Cardiovascular risk and lifestyle advice from physician: rates recalled by patients and predicting factors.
Ho Cheol Shin
J Korean Acad Fam Med 2001;22(11):1656-1669.   Published online November 1, 2001
Background
: The relation between lifestyle and chronic diseases in now well established. For example, smoking, high dietary fat intake, lack of exercise have been identified as independent risk factors for the development of cardiovascular disease. So changing risk factors related to lifestyle is very important to minimize the burden of many kinds of chronic diseases including cardiovascular disease and cancer. Patients who are at increased risk of developing chronic diseases should be identified and if this increased risk is modifiable unhealthy behavior, appropriate advice should be given to encourage behavioral change. That is one of the most important role of primary care physician. However, we do not know how often patients with varying risk factors receive lifestyle advice from their physician in Korea. This study is to know how often patients having cardiovasculr risk factors receive lifestyle advice from their physician and what is the predicting factor of that.

Methods : Cross-sectional study was done by direct interview. Subjects were 3151 people aged 19-61 years who had consulted a physician at leat once during 12 months before interview and who were employee of the national company which had branches nationwide. Possible cardiovascular risk factors were identified from the result of health check. Subjects were asked whether they had received lifestyle advice for each of identified risk factors from physician. The data about sociodemographic characteristics also were collected during interview. We used x2 test for trend to establish whether increasing risk levels were associated with a change in the likelihood of receiving advice about modifying risky behaviors.

Results : The proportion of smokers who received advice about smoking was just 29.3%, but smoking was unhealthy behavior most likely to receive advice from physician. The proportion of subjects receiving advice about exercise was only 8.6% and was significantly higher among those who were diabetic (27.6%), hypertensive (22.7%), or who had a history of cardiovascular disease (36.4%). The proportion of subjects receiving advice about low dietary fat intake was only 6.8%. The proportion was higher among obese subjects (13.7%) and rose with increasing serum cholesterol level (x2 trend=9.46, df=1; p<0.01). The proportion of subjects receiving advice about alcohol consumption was 18.1%. Women were significantly less likely than men to receive advice about smoking, exercise, alcohol consumption except about dietary intake and weight control. Age was significantly associated with the likelihood of receiving lifestyle advice.

Conclusion : Patients reported a low rate of receiving lifestyle advice from physician. This results suggest that more preventive advice about healthy lifestyle should be given in primary care.
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The comparision of the quality of life between the well controlled hypertension group and the uncontrolled hypertension group.
Young Mook Kim, Hyun Rim Choi, Do Young Park, Jong Bum Lim, Chang Won Won, Byung Sung Kim, Yong Woo Park
J Korean Acad Fam Med 2001;22(4):565-574.   Published online April 1, 2001
Background
: Hypertension is an important as well as common disease in primary practice, so family physicians should concern about it. It is well known that if hypertension were well controlled, it could lower cardiovascular complications. However, there are few studies on the impact of hypertension affecting the quality of life. Therefore, we carried out this study to compare the quality of life in the hypertensive patients by whether it is well controlled or not.

Methods : The authors surveyed the quality of life using the questionnaire named as CMC Health Survey Version 1.0 for the hypertensive patients. The subjects had no complications and no other diseases, and aged 40 or more, and visited doctors at the Department of Family Medicine, Kyung-Hee University Hospital or the Department of Internal Medicine, Sungmin Hospital from May 1 to Aug 31, 1998. We categorized the subjects into the two groups of the well-controlled group(SBP<140mmHg and DBP<90 mmHg) and the uncontrolled group(SBP≥140mmHg or DBP ≥ 90mmHg) and compared the quality of life and lifestyle.

Results : The total number of subjects was 119, that of well-controlled group was 69, and that of the uncontrolled group was 50. Mean systolic and diastolic blood pressure was 133.1±7.5mmHg and 85.3±5.2 mmHg in the well-controlled group, 159.2±7.4 mmHg and 100.2±5.5 mmHg in the uncontrolled group. The comparison of the distribution of age, sex, education, occupation, and monthly income between the two groups showed no difference. The comparision of the lifestyle between two groups by Alameda-7 questionnaire showed no difference, too. As for the comparison of quality of life between two groups, the well-controlled group had significantly higher scores in the domain of physical function, social function, general health, vitality(above P<0.01), emotional function, role limitation, and health perception(above P<0.05) than uncontrolled group. However, the scores of the domain of change in health, satisfaction, bodily pain were not significantly different between two groups. After covariated by obesity, the comparison of quality of life between two groups showed similar results.

Conclusion : We confirmed that the well-controlled group had better quality of life than the uncontrolled group. So family physicians should consider the quality of life when they consult the patients with hypertension.
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Effects of changes in lifestyle and biological parameters on blood lipid levels in middle aged men.
Hoon Il Kang, Young Ho Youn, Jin Yi Kang, Jung Jin Cho
J Korean Acad Fam Med 2000;21(6):782-791.   Published online June 1, 2000
Background
: Death form coronary heart disease is increasing and this study is to evaluate the effect of longitudinal changes of lifestyle and biological parameters on the blood lipid levels, as the risk factor of the coronary heart disease.

Methods : Total cholesterol and total cholesterol to HDL-cholesterol ratio (atherosclerogenic index) as an indicator for risk of coronary heart disease were examined longitudinally in sample(n=463) of middle-aged men by 2 years. The independent variables were body mass index, smoking, alcohol, exercise, diastolic blood pressure, uric acid. All data was drawn form questionnaire, blood chemistry, and review of chart.

Results : ANOVA test according to categorized variables revealed that for total cholesterol, uric acid (P<0.01) and diastolic blood pressure (P<0.01), and for atherosclerogenic index, and body mass index (P<0.001) were significant. In correlation analysis, total cholesterol was associated with uric acid (r=0.20, P<0.001), diastolic blood pressure(r=0.15, P<0.001) and body mass index(r=0.30, P<0.05). and for atherosclerogenic index so was body mass index (r=0.18, P<0.001). In regression, uric acid(β=6.07, P<0.001), diastolic blood pressre(β=0.36, P<0.01) for total cholesterol, and body mass index(β=0.22, P<0.001) for atherosclerogenic index were significant. But changes in alcohol consumption, smoking, and exercise were not statistically significant.

Conclusion : In order to reduce risks of coronary heart disease, the more aggressive medical intervention for the uric acid, DBP, and BMI, would be essential. This study was done without medical intervention. So, further study with intervention, adequate duration and intensity for parameters modification is required.
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Compliance with lifestyle modification in patients with hypertension.
Byung Kwan Lee, Yun Mi Song, Kong Jin Kim, Sung Ho Do
J Korean Acad Fam Med 1999;20(12):1709-1720.   Published online December 1, 1999
Background
: Advising lifestyle modification to patients suffering from hypertension is important. However, how strictly hypertensive patients in Korea are adherent to non-pharmacologic recommendation has not been well known. This study was performed to determine the compliance of hypertensive patients to the recommendation for life style modification and to find out on factors related to compliance.

Methods : Ninety ? six patients, diagnosed as hypertensive between November 1997 and April 1998 in the Department of Family Medicine, Samsung Medical Center were educated on lifestyle modifications by their physicians during routine outpatient consult questionnaires inquiring of demographic and clinical characteristics, and health habits were Self administered done before and after the education. Blood pressure, height, and weight were measured repeatedly. The relationships between various characteristics and the compliance with lifestyle modification and follow-up visits were evaluated using Chi-square test and multiple logistic regression analysis.

Results : Among 96 patients, 47 patients(49.0%) attended for regular check-up two months after being diagnosed as hypertension. Being prescribed with antihypertensive agent, non-smoking, and doing regular exercise were the significant factors related to higher compliance with regular check-up. A total of 19 patients (40.4%) among 47 patients who have attended for regular check-up were adherent to the recommendation for modification of one or more health habits. The proportion of patients doing regular exercise increased significantly after education. Although 15 patients(53.6%) among 28 patients whose body mass indices were over 25 km/㎡ reported that they had made efforts to reduce body weight, no significant differences were observed in the change of body mass index between patients who reported their efforts for reducing body weight and those who did not. There was no association between various characteristics and compliance with lifestyle modification.

Conclusion : Low compliance with recommendation for lifestyle modification during routine outpatient consultation and no association between various clinical and demographic characteristics and patient compliance suggests the necessity of developing special program and its active application to all hypertensive patients. ( J Korean Acad Fam Med 1999;20:1709-1720)
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A study of subjective symptoms and life styles among long term computer users.
Se Hyeung Park, Chang Hee Park, Young Sung Suh, Dae Hyun Kim, Seong Ryong Lee
J Korean Acad Fam Med 1998;19(8):630-641.   Published online August 1, 1998
Background
: The effect of Video Display Terminals(VDT) Syndrome is well documented. The purpose of this study is to examine the difference in systemic subjective symptoms between long term users of computers with that of the general population and to help plan to avoid the risk of developing Video Display Terminal Syndrome.

Methods : Data was collected for this study between August 1996 and February 1997. Two groups consisting of seventy(70) long term computer users(Exposed Subjects) and fifty-nine(59) non users(Non Exposed Subjects), were selected for the survey. Data were gathered from the exposed subjects through their response to the survey questionnaire posted on the internet requiring detailed responses concerning ten systemic subjective symptoms that were experienced as a result of the long term exposure to VDT. Data were gathered from the non-exposed subjects through written responses to the questionnaire.

Results : Among the more significant difference was the experience of ocular symptoms among the exposed group. The exposed group experienced in descending order eleven items of ocular symptoms: congestion, strain, decreased visual acuity, ocular pain, and dryness. Among seven items of lifestyle, the exposed group characteristically exercised less(P<0.05) and did more home activity(P<0.05), characteristically lead healthier life than the non-exposed group. Particiption in exercise differed most among the groups. The exposed group participating in moderate exercise scored 517±551.6 compared to the non-exposed group which exercised very vigorously(p<0.05). In comparison of subjective symptom and life styles per daily exposure time(over 8, 10, 16 hours daily) there was significant difference between 8 and 10 hour exposers only in the stress item(P<0.05). In the exposure group there were less cardiovascular symptoms(P<0.05) due to more art activity(P<0.05), more cardiovascular symptoms and less sleep activity(P<0.001) and more ocular symptoms(P<0.05) due to higher levels of stress.

Conclusion : By exercising, exposers can decrease the respiratory symptoms, and by seeking methods that enable efficient management of work time, the subjects can benefit from the reduced work time, and by seeking methods so that one receive less stress and can resolve them they can reduce their ocular symptoms, sleep problems, cardiovascular symptoms. And in their spare time, the subjects can be recommended to involve in art activity for each person, through PC indirectly. Designing the development of cyber gallery, museum, literature room, concert can reduce the occurrence rate of cardiovascular symptoms.
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