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Original Article

The Effect of Vitamin C for Mercury Excretion by Hair Mercury Analysis.

Jeong Yun Lee, Ho Seob Lihm, Jong Soon Choi, Hyeong Soo Cha
Korean Journal of Family Medicine 2009;30(9):717-722.
Published online: September 20, 2009
1Department of Family Medicine, Kosin University College of Medicine, Busan, Korea. fmcjs@naver.com
2Centum Family Clinic, Busan, Korea.
고신대학교 의과대학 가정의학교실, 1센텀가정의원
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Background
Humans are exposed to mercury via many different routes and in different forms. Studies concerned with the exposure in the general population were done many times in the past. But, the treatment of mercury exposure and mercury intoxication is limited. Therefore, chelators such as birth anti lewistite, 2,3-dimercaptopropanol (BAL), dimercaptopropane-1-sulphonate (DMPS), and dimercaptosuccinic acid (DMSA) were given to patients with acute symptoms resulting from the central nervous system due to confi rmed mercury poisoning. In this paper, we reported the effects of oral Vitamin C on mercury excretion Methods: This study has been reviewed in the clinical fi ndings of 213 patients aged 30-80 who visited Kosin University Gospel Hospital during 3 months from March to September 2007. We measured hair mercury levels at the initial visit and at 3-4 months after the oral vitamin C (4 g/day) treatment. Results: The number of patients who had initial hair mercury level over 1.5 ppm were 57 patients among 213 patients, and 41 patients rechecked the hair mercury level. Twenty patients who had hair mercury level over 1.5 ppm were treated with oral vitamin C for 3 months and rechecked the hair mercury level and 21 patients without vitamin C treatment. The vitamin treatment group had a hair mercury level that was three times lower than the non-treated group. Conclusion: The vitamin C oral treatment signifi cantly decreased the level of hair mercury.

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