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Korean J Fam Med > Volume 30(9); 2009 > Article
Korean Journal of Family Medicine 2009;30(9):703-709.
DOI: https://doi.org/10.4082/kjfm.2009.30.9.703    Published online September 20, 2009.
Relationship between Brand Nicotine Yield of Cigarettes and Urine Cotinine Level in Male Smokers.
Sang Ho Yoon, Yu Jin Paek, Sang Ho Yoo, Jung Jin Cho, Hong Ji Song, Kyung Hee Park, Hye Mi Chang, Jin Hwa Ban
Department of Family Medicine, Hallym University College of Medicine, Hallym Sacred Heart Hospital, Anyang, Korea. paek@hallym.co.kr
담배의 표기된 니코틴 함량과 요코티닌 수치의 관계
윤상호, 백유진, 유상호, 조정진, 송홍지, 박경희, 장혜미, 반진화
한림대학교 의과대학 한림대성심병원 가정의학교실
As one of harm reduction strategies, tobacco manufacturers have begun to introduce lower-yield cigarettes. Lower-yield cigarettes, so called light cigarettes, have been perceived as less hazardous by some smokers. However, there have been very few studies concerning smoking lower yield products the lead to lower nicotine absorption. We evaluated the association between brand nicotine yield of cigarettes and actual nicotine intake by measuring urinary cotinine. Methods: Four hundred sixty four male smokers aged 18 or over who participated in health check-ups in a hospital from May to October 2007 fi lled out a self-administered smoking questionnaire. Urinary cotinine concentration was measured at the time of participation. The subjects were divided into three groups (ultralight [nicotine: 0.05 mg], light [0.1 mg], and regular [> 0.1 mg] group) according to the level of brand nicotine yield of cigarettes which they smoked. Results: The median urinary cotinine concentrations of ultralight (N = 62), light (N = 216), and regular (N = 186) groups were 735.5 ng/mL (interquartile range, 320 to 1,300 ng/mL), 956.0 ng/mL (429 to 1,491 ng/mL), and 1,067.5 ng/mL (615 to 1,613 ng/mL), respectively. There was a signifi cant difference in urinary cotinine between the regular and the other groups (P = 0.015). However, multiple logistic regression analysis to evaluate the risk of being in the highest quartile of urinary cotinine concentration (≥ 1,532 ng/mL) after adjusting for possible confounding variables showed that the odds ratios were 0.84 (95% CI, 0.52 to 1.37) in the light nicotine group and 0.82 (95% CI, 0.38 to1.72) in the ultralight nicotine group compared to the regular nicotine group. Conclusion: There was no significant difference in the risk of elevated urinary cotinine concentrations in male adult smokers according to brand nicotine yield of cigarettes groups.
Key Words: Cigarettes; Tobacco; Smoking; Nicotine; Tar; Urinary Cotinine


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