Journal of the Korean Academy of Family Medicine 1990;11(9):15-22.
Published online September 1, 1990.

비궤양성 소화불량증과 스트레스에 대한 연구 (A Case Control Study on Non-Ulcer Dyspepsia and Stress)

윤방부(Youn Bang Bu),이혜리(Lee Hye Ree),박계열(Park Kye Yeol),박병일(Park Byung Il),이선권(Lee Sun Kwon),조동영(Cho Dong Yung)

연세대학교의과대학 가정의학교실 서울기독병원

Abstract

Stress is purported to be a major cause of non-ulcer dyspepsia, defined here as non-ulcer dyspepsia where peptic ulcer, esophagitis, acute gastroduodenitis, and cancer are excluded by endoscopy. The aim of the present study was to determine if stress, as measured by major life events(SRS, Social Readjustment Scale) and degree of stress perception(BEPSI), was associated with non-ulcer dyspepsia. The life change scores during the year before the diagnosis of non-ulcer dyspepsia and BEPSI scores in 88 patients were compared with those in 81 selective non-matched community controls. The negative life change scores in non-ulcer dyspepsia patients were significantly higher than those in controls(P<0.05) but there were no significant differences in positive and total life change scores between two groups. The BEPSI scores in non-ulcer dyspepsia patients were more significantly higher than those in controls(P<0.01). It was found that BEPSI scores were moderately correlated with negative life change scores(r=0.36, P<0.001) but not with positive scores. The above results indicate that the cause of non-ulcer dyspepsia may be associated with negative stresser via stress perception.